Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.

Cited by (834)

Items 601–700 of 834

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8. The effect of protein levels of ABO on pregnancy related outcomes: a Mendelian randomization study
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9. Mendelian randomization revealing the protective effect of sodium-glucose cotransporter 2 inhibition on prostate cancer with verified evidence from electronic healthcare and biological data
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10. Membranous Nephropathy: Muti-omics Mendelian randomization and colocalization analysis
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11. Single-cell and genome-wide Mendelian randomization identifies causative genes for gout
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12. Therapeutic Targets for Colorectal Cancer: Proteome-Wide and Genome-Wide Mendelian Randomization and Colocalization Analyses
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13. Circulating inflammatory proteins may be potential drug targets for Idiopathic Membranous Nephropathy: proteome-wide Mendelian Randomization and colocalization analysis
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14. Type 2 Diabetes Mellitus and the Risk of Prostate Cancer: A Mendelian Randomization Study
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16. Response to Yarmolinsky, Tzoulaki, Gunter, et al.
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17. The Associations of Circulating Inflammatory-Related Proteins with Asthma: A Mendelian Randomization Study
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18. Reverse Mendelian randomization separates causes from early proteomic biomarkers of glioma
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19. Dissecting shared genetic architecture between hypothyroidism and immune-related diseases
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20. Additional file 2 of Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis
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21. Additional file 1 of Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage
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22. Additional file 1 of Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome
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23. Large-Scale Proteome-Wide Mendelian Randomization Identifies Novel Proteins for Glaucoma and Related Traits
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24. Genetic mapping of plasma proteome on brain structure
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25. Mendelian randomization Identifies RSPO3 in Serum as a Potential Target for Endometriosis
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26. Large-Scale Proteome-Wide Mendelian Randomization Identifies Novel Proteins for Glaucoma and Related Traits
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27. Identification of MAN1A2 as Potential Drug Target for Restless Legs Syndrome: A Comprehensive Mendelian Randomization Study
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28. Associations between genetically predicted TIMP-3 levels and risk of venous thromboembolism: A two sample Mendelian randomization study
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29. Cause or consequence in idiopathic pulmonary fibrosis: using genetic data to back the right horse
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32. Identification of Emerging Drug Targets for Pulmonary Functions Through Mendelian Randomization Analysis of the Plasma Proteome
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33. Genetically-Proxied Lower PAR1 and Renal Phenotypes: A Drug-Target Mendelian Randomization Study
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35. Potential drug targets for prostate cancer ： A mendelian randomization study and application for target-derived drug design
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36. Mendelian randomization suggests a causal link between glycemic traits and thoracic aortic structures and diseases
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37. Angiotensin-converting enzyme inhibition and Alzheimer’s disease: Findings from proteome-wide Mendelian randomization and a large prospective cohort study
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38. Elucidating the Causal Impact of Plasma Proteins on Osteoporosis Risk and the Mediating Role of Immune Cells through Integrated Multi-omics Data Analysis
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39. Novel common target genes for breast cancer and colorectal cancer: A mendelian randomization and spatial transcriptomics study
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40. Comprehensive Druggable Genome-Wide Mendelian Randomization Reveals Therapeutic Targets for Kidney Diseases
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41. Computational Approaches to Identification and Characterization of Masitinib as Potential Treatment for Alzheimer's Disease through Molecular Docking and Two-sample Mendelian Randomization
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42. CCN3/NOV as a potential therapeutic target for diverticular disease: A proteome-wide Mendelian randomization study
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43. Revealing potential drug targets in schizophrenia through proteome-wide Mendelian randomization genetic insights
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44. Long-Chain Polysaturated Fatty Acid in Atrial Fibrillation–Associated Stroke: Lipidomic-GWAS Study
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45. Identification of biomarkers for chronic lymphocytic leukemia risk: a proteome-wide Mendelian randomization study
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46. Serum proteomic correlates of mental health symptoms in a representative UK population sample
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47. Identification of CD209 as an Intervention Target for Type 2 Diabetes After COVID-19 Infection: Insights From Proteome-Wide Mendelian Randomization
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48. Assessing the Causal Impact of the Circulating Proteome on Susceptibility to Gastrointestinal Cancer-Associated Characteristics
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49. Oral Metformin May Exacerbate Diabetic Neuropathy: A Two-Sample Mendelian Randomization Study
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50. Prioritization of potential drug targets in ovarian-related diseases: Mendelian randomization and colocalization analyses
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51. Discovering genetically-supported drug targets for multisite chronic pain through multi-omics Mendelian randomization and single-cell RNA-sequencing.
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52. Identifying Circulating Protein Mediators in the Link Between Smoking and Abdominal Aortic Aneurysm: An Integrated Analysis of Human Proteomic and Genomic Data
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55. Therapeutic Targets for Multiple System Atrophy
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56. Potential Therapeutic Strategies Targeting CRELD1: Regulation of the Immune Microenvironment in Clear Cell Renal Cell Carcinoma
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58. Causal Associations of Metformin with Five Interleukin Receptors: Uncovering Potential Anti-inflammatory Mechanisms through Mendelian Randomization
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59. Shared proteomic landscape between arteriosclerosis and cardiovascular endpoints: a Mendelian randomization and observational study integrating AlphaFold3 for structural prediction
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60. Causal Associations of Cardiovascular Proteins and Diabetic Nephropathy Revealed by Mediation and Phenome-Wide Mendelian Randomization
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61. Mendelian randomization analysis reveals the potential of the IKZF1 gene as a therapeutic target in colorectal cancer
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62. Evidence from a Comprehensive Bioinformatics Analysis Point to Possible Therapeutic Targets for Vitiligo
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63. Exploring causal plasma protein level ratios and potential drug targets for depression: A proteomics Mendelian randomization study
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64. The long non-coding RNA TRIB1AL links metabolic dysfunction-associated steatotic liver disease, cardiometabolic risk and human lifespan
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72. Mechanistic Study of NT5E in Reg3β-Induced Macrophage Polarization and Cooperation with Plasma Proteins in Myocarditis Injury and Repair
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