Neuropathological Alterations in Alzheimer Disease

Serrano-Pozo, A., Frosch, M. P., Masliah, E., Hyman, B. T.·2011·Cold Spring Harbor Perspectives in Medicine

DOI 10.1101/cshperspect.a006189

Cited by (1,029)

Items 201–300 of 1,029

Sleep Duration and Subsequent Cortical Thinning in Cognitively Normal Older Adults
Adam P. Spira, Christopher E. Gonzalez, Vijay K. Venkatraman, Mark N. Wu, Jennifer L. Pacheco, Eleanor Marie Simonsick, Luigi Ferrucci, Susan M. Resnick · 2016 · SLEEP
Role of the peripheral innate immune system in the development of Alzheimer's disease
Aurélie Y. Le Page, Gilles Dupuis, Eric H. Frost, Anis Larbi, Graham Pawelec, Jacek Maciej Witkowski, Tamàs Fülöp · 2017 · Experimental Gerontology
Alzheimer’s Disease Pathogenesis: Role of Autophagy and Mitophagy Focusing in Microglia
Eshraghi, Mehdi, Adlimoghaddam, Aida, Mahmoodzadeh, Amir, Sharifzad, Farzaneh, Yasavoli-Sharahi, Hamed, Lorzadeh, Shahrokh, Albensi, Benedict C., Ghavami, Saeid · 2021 · International Journal of Molecular Sciences
Brain somatic mutations observed in Alzheimer’s disease associated with aging and dysregulation of tau phosphorylation
Park, Jun Sung, Lee, Junehawk, Jung, Eun Sun, Kim, Myeong-Heui, Kim, Il Bin, Son, Hyeonju, Kim, Sangwoo, Kim, Sanghyeon, Park, Young Mok, Mook-Jung, Inhee et al. · 2019 · Nature Communications
Synthesis and Multitarget Biological Profiling of a Novel Family of Rhein Derivatives As Disease-Modifying Anti-Alzheimer Agents
Elisabet Viayna, Irene Sola, Manuela Bartolini, Angela De Simone, Cheril Tapia‐Rojas, Felipe G. Serrano, Raimon Sabaté, Jordi Juárez‐Jiménez, Belén Pérez, Francisco Javier Luque et al. · 2014 · Journal of Medicinal Chemistry
Passive immunotherapies targeting Aβ and tau in Alzheimer's disease
Steven Samuel Plotkin, Neil R. Cashman · 2020 · Neurobiology of Disease
Neuroinflammation represents a common theme amongst genetic and environmental risk factors for Alzheimer and Parkinson diseases
Rachel J. Boyd, Dimitrios Avramopoulos, Lauren L. Jantzie, Andrew S. McCallion · 2022 · Journal of Neuroinflammation
Mechanism involved in insulin resistance via accumulation of β-amyloid and neurofibrillary tangles: link between type 2 diabetes and Alzheimer’s disease
Sima Kianpour Rad, Aditya Arya, Hamed Karimian, Priya Madhavan, Farzana Rizwan, Shajan Koshy, Girish Prabhu · 2018 · Drug Design Development and Therapy
Is Alzheimer’s Disease Risk Modifiable?
Alberto Serrano‐Pozo, John H. Growdon · 2019 · Journal of Alzheimer s Disease
Alzheimer’s Disease as a Membrane Disorder: Spatial Cross-Talk Among Beta-Amyloid Peptides, Nicotinic Acetylcholine Receptors and Lipid Rafts
Camila Fabiani, Silvia S. Antollini · 2019 · Frontiers in Cellular Neuroscience
Amyloid-β-dependent compromise of microvascular structure and function in a model of Alzheimer’s disease
Adrienne E. Dorr, Bhupinder Sahota, Lakshminarayan V. Chinta, Mary E. Brown, Aaron Y. Lai, Keran Ma, Cheryl A. Hawkes, JoAnne McLaurin, Bojana Stefanovic · 2012 · Brain
Recent advances in the neurobiology and neuropharmacology of Alzheimer’s disease
Kushal Kumar, Ashwani Kumar, Richard M. Keegan, Rahul R Deshmukh · 2017 · Biomedicine & Pharmacotherapy
A Life-Course Study of Cognitive Reserve in Dementia—From Childhood to Old Age
Serhiy Dekhtyar, Hui‐Xin Wang, Kirk Scott, Anna Goodman, Ilona Koupil, Agneta Herlitz · 2015 · American Journal of Geriatric Psychiatry
Pathology of the Aging Brain in Domestic and Laboratory Animals, and Animal Models of Human Neurodegenerative Diseases
Sameh A. Youssef, Maria Tresa Capucchio, Jaime Rofina, James Kenn CHAMBERS, Kazuyuki Uchida, Hiroyuki Nakayama, Elizabeth Head · 2016 · Veterinary Pathology
Exosomes in Alzheimer's disease
Tarja Malm, Sanna H. Loppi, Katja M. Kanninen · 2016 · Neurochemistry International
Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect Aβ aggregation features and cross the blood–brain-barrier: Implications for therapy of Alzheimer disease
Laura Bana, Stefania Minniti, Elisa Salvati, Silvia Sesana, Vanessa Zambelli, Alfredo Cagnotto, Antonina Orlando, Emanuela Cazzaniga, Rob Zwart, Wiep Scheper et al. · 2013 · Nanomedicine Nanotechnology Biology and Medicine
TNF-α-dependent neuronal necroptosis regulated in Alzheimer's disease by coordination of RIPK1-p62 complex with autophagic UVRAG
Chong Xu, Jialin Snow Wu, Yiqun Wu, Zhichu Ren, Yuyuan Yao, Guobing Chen, Evandro Fei Fang, Ji Heon Noh, Yong Liu, Libin Wei et al. · 2021 · Theranostics
Spreading of Tau Pathology in Sporadic Alzheimer’s Disease Along Cortico-cortical Top-Down Connections
Braak, Heiko, Del Tredici, Kelly · 2018 · Cerebral Cortex
Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer’s Disease
Fabian Cabezas-Opazo, Katiana Vergara-Pulgar, Maria Jose Perez J., Claudia Jara, Cesár Osorio‐Fuentealba, Rodrigo A. Quintanilla · 2015 · Oxidative Medicine and Cellular Longevity
Amyloid β oligomers (AβOs) in Alzheimer’s disease
Barbara Mroczko, Magdalena Groblewska, Ala Litman‐Zawadzka, Johannes Kornhuber, Piotr Lewczuk · 2017 · Journal of Neural Transmission
Profound degeneration of wake‐promoting neurons in Alzheimer's disease
Jun Yeop Oh, Rana April Eser, Alexander J. Ehrenberg, Dulce Ovando Morales, Cathrine Petersen, Jessica Kudlacek, Sara Rose Dunlop, Panos Theofilas, Elisa de Paula França Resende, Celica Glenn Cosme et al. · 2019 · Alzheimer s & Dementia
The amyloid plaque proteome in early onset Alzheimer’s disease and Down syndrome
Drummond, Eleanor, Kavanagh, Tomas, Pires, Geoffrey, Marta-Ariza, Mitchell, Kanshin, Evgeny, Nayak, Shruti, Faustin, Arline, Berdah, Valentin, Ueberheide, Beatrix, Wisniewski, Thomas · 2022 · Acta Neuropathologica Communications
Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration
Peng Liu, Miranda N. Reed, Linda Kotilinek, Marianne K. O. Grant, Colleen L. Forster, Wei Qiang, Samantha L. Shapiro, John H. Reichl, Angie C.A. Chiang, Joanna L. Jankowsky et al. · 2015 · Cell Reports
Gold Nanoparticles Treatment Reverses Brain Damage in Alzheimer’s Disease Model
Natália dos Santos Tramontin, Sabrina da Silva, Rychard Arruda, Kellen Ugioni Simon, Paula Bortoluzzi Canteiro, Gustavo de Bem Silveira, Carolini Mendes, Paulo César Lock Silveira, Alexandre Pastoris Muller · 2019 · Molecular Neurobiology
Liver Dysfunction as a Novel Player in Alzheimer’s Progression: Looking Outside the Brain
Estrada, Lisbell D., Ahumada, Pablo, Cabrera, Daniel, Arab, Juan P. · 2019 · Frontiers in Aging Neuroscience
Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models
Sethu Sankaranarayanan, Donna M. Barten, Laurel Vana, Nino Devidze, Ling Yang, Gregory W. Cadelina, Nina Hoque, Lynn B. DeCarr, Stefanie Keenan, Alan Lin et al. · 2015 · PLoS ONE
Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer¿s disease
Hwan‐Ching Tai, Bo Y. Wang, Alberto Serrano‐Pozo, Matthew P. Frosch, Tara L. Spires‐Jones, Bradley T. Hyman · 2014 · Acta Neuropathologica Communications
EGCG ameliorates high‐fat– and high‐fructose‐induced cognitive defects by regulating the IRS/AKT and ERK/CREB/BDNF signaling pathways in the CNS
Yashi Mi, Guoyuan Qi, Rong Fan, Qinglian Qiao, Yali Sun, Yu-Qi Gao, Xuebo Liu · 2017 · The FASEB Journal
Copper Toxicity Links to Pathogenesis of Alzheimer’s Disease and Therapeutics Approaches
Hafza Wajeeha Ijaz, Wei Wang, Minglin Lang · 2020 · International Journal of Molecular Sciences
Why looking at the whole hippocampus is not enough—a critical role for anteroposterior axis, subfield and activation analyses to enhance predictive value of hippocampal changes for Alzheimer’s disease diagnosis
Aleksandra Maruszak, Sandrine Thuret · 2014 · Frontiers in Cellular Neuroscience
Templated misfolding of Tau by prion-like seeding along neuronal connections impairs neuronal network function and associated behavioral outcomes in Tau transgenic mice
Stancu, Ilie-Cosmin, Vasconcelos, Bruno, Ris, Laurence, Wang, Peng, Villers, Agnès, Peeraer, Eve, Buist, Arjan, Terwel, Dick, Baatsen, Peter, Oyelami, Tutu et al. · 2015 · Acta Neuropathologica
Stem cell models of Alzheimer’s disease: progress and challenges
Arber, Charles, Lovejoy, Christopher, Wray, Selina · 2017 · Alzheimer's Research & Therapy
Inadequate supply of vitamins and DHA in the elderly: Implications for brain aging and Alzheimer-type dementia
Mohajeri, M. Hasan, Troesch, Barbara, Weber, Peter · 2015 · Nutrition
G lycation in P arkinson's disease and Alzheimer's disease
Hugo Vicente Miranda, Omar M. A. El‐Agnaf, Tiago F. Outeiro · 2016 · Movement Disorders
Specific Signatures of Serum miRNAs as Potential Biomarkers to Discriminate Clinically Similar Neurodegenerative and Vascular-Related Diseases
Cristina Barbagallo, Giovanni Mostile, Gloriangela Baglieri, Flavia Giunta, Antonina Luca, Loredana Raciti, Mario Zappia, Michele Purrello, Marco Ragusa, Alessandra Susie Quesado Nicoletti · 2019 · Cellular and Molecular Neurobiology
The Relation of the Brain-Derived Neurotrophic Factor with MicroRNAs in Neurodegenerative Diseases and Ischemic Stroke
Ceren Eyileten, Lucia Sharif, Zofia Wicik, Daniel Jakubik, Joanna Jarosz-Popek, Aleksandra Soplińska, Marek A Postula, Anna Członkowska, Agnieszka Kapłon‐Cieślicka, Dagmara Maria Mirowska-Guzel · 2020 · Molecular Neurobiology
Ocular Neurodegenerative Diseases: Interconnection between Retina and Cortical Areas
Nicoletta Marchesi, Foroogh Fahmideh, Federica Boschi, Alessia Pascale, Annalisa Barbieri · 2021 · Cells
Flavonoids as Promising Neuroprotectants and Their Therapeutic Potential against Alzheimer’s Disease
Tarun Minocha, Hareram Birla, Ahmad A. Obaid, Vipin Rai, Sushma Pradeep, Chandan Shivamallu, Mahmoud Moustafa, Mohammed Al-Shehri, Ahmed Al‐Emam, Maria A. Tikhonova et al. · 2022 · Oxidative Medicine and Cellular Longevity
The Role of the JAK/STAT Signaling Pathway in the Pathogenesis of Alzheimer’s Disease: New Potential Treatment Target
Marta Rusek, Joanna Smith, Kamel El-Khatib, Kennedy Aikins, Stanisław Jerzy Czuczwar, Ryszard M. Pluta · 2023 · International Journal of Molecular Sciences
APOE Stabilization by Exercise Prevents Aging Neurovascular Dysfunction and Complement Induction
Soto, Ileana, Graham, Leah C., Richter, Hannah J., Simeone, Stephen N., Radell, Jake E., Grabowska, Weronika, Funkhouser, W. Keith, Howell, Megan C., Howell, Gareth R. · 2015 · PLOS Biology
Cardiolipin Profile Changes are Associated to the Early Synaptic Mitochondrial Dysfunction in Alzheimer's Disease
Vera Filipa Monteiro-Cardoso, Maria Manuel Oliveira, Tânia Melo, M. Rosário Domingues, Paula Isabel Moreira, Elisabete B. Ferreiro, Francisco Peixoto, Romeu António Videira · 2014 · Journal of Alzheimer s Disease
Chitosan as a suitable nanocarrier material for anti-Alzheimer drug delivery
Jayrajsinh Sarvaiya, Yadvendra Kumar Agrawal · 2014 · International Journal of Biological Macromolecules
Review: Neurodegenerative processes in temporal lobe epilepsy with hippocampal sclerosis: Clinical, pathological and neuroimaging evidence
Xin You Tai, Boris C. Bernhardt, Maria Thom, Pamela Jane Thompson, Sallie Baxendale, Matthias J. Koepp, Neda Bernasconi · 2017 · Neuropathology and Applied Neurobiology
Therapeutic Potentials of Microalgae in the Treatment of Alzheimer’s Disease
Tosin Abiola Olasehinde, Ademola Olufolahan Olaniran, Anthony Ifeanyi Okoh · 2017 · Molecules
COVID-19 and Alzheimer’s disease: how one crisis worsens the other
Xiaohuan Xia, Yi Wang, Jialin Zheng · 2021 · Translational Neurodegeneration
Removing endogenous tau does not prevent tau propagation yet reduces its neurotoxicity
Wegmann, Susanne, Maury, Eduardo A, Kirk, Molly J, Saqran, Lubna, Roe, Allyson, DeVos, Sarah L, Nicholls, Samantha, Fan, Zhanyun, Takeda, Shuko, Cagsal‐Getkin, Ozge et al. · 2015 · The EMBO Journal
Intracellular Calcium Dysregulation: Implications for Alzheimer’s Disease
Simona Magi, Pasqualina Castaldo, Maria Loredana Macrì, Marta Maiolino, Alessandra Matteucci, Guendalina Bastioli, Santo Gratteri, Salvatore Amoroso, Vincenzo Lariccia · 2016 · BioMed Research International
Targeting Neuroinflammation as a Therapeutic Strategy for Alzheimer’s Disease: Mechanisms, Drug Candidates, and New Opportunities
Wing‐Yu Fu, Xiujiao Wang, Nancy Y. Ip · 2018 · ACS Chemical Neuroscience
A Machine Learning Approach for the Differential Diagnosis of Alzheimer and Vascular Dementia Fed by MRI Selected Features
Castellazzi, Gloria, Cuzzoni, Maria Giovanna, Cotta Ramusino, Matteo, Martinelli, Daniele, Denaro, Federica, Ricciardi, Antonio, Vitali, Paolo, Anzalone, Nicoletta, Bernini, Sara, Palesi, Fulvia et al. · 2020 · Frontiers in Neuroinformatics
Contribution of the Nrf2 Pathway on Oxidative Damage and Mitochondrial Failure in Parkinson and Alzheimer’s Disease
Francisca Villavicencio-Tejo, Rodrigo A. Quintanilla · 2021 · Antioxidants
Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment
Chakrabarti, Sasanka, Kumar Khemka, Vineet, Banerjee, Anindita, Chatterjee, Gargi, Ganguly, Anirban, Biswas, Atanu · 2015 · Aging and disease
Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease
Melissa K. Edler, Chet C. Sherwood, Richard S. Meindl, William Donald Hopkins, John J. Ely, JOSEPH M. ERWIN, Elliott Jay Mufson, Patrick R. Hof, Mary Ann Raghanti · 2017 · Neurobiology of Aging
Molecular Insight into the Therapeutic Promise of Flavonoids against Alzheimer’s Disease
Md. Sahab Uddin, Md. Tanvir Kabir, Kamal Niaz, Philippe Jeandet, Christophe Clément, Bijo Mathew, Abdur Rauf, Kannan R. R. Rengasamy, Eduardo Sobarzo‐Sánchez, Ghulam Md Ashraf et al. · 2020 · Molecules
Glycolytic Metabolism, Brain Resilience, and Alzheimer’s Disease
Zhang, Xin, Alshakhshir, Nadine, Zhao, Liqin · 2021 · Frontiers in Neuroscience
Cognitive Decline in Preclinical Alzheimer’s Disease: Amyloid-Beta versus Tauopathy
Colin M. Huber, Connor Yee, Taylor May, Apoorva Dhanala, Cassie S. Mitchell · 2017 · Journal of Alzheimer s Disease
Region-specific depletion of synaptic mitochondria in the brains of patients with Alzheimer’s disease
Eleanor K. Pickett, Jamie L. Rose, Caoimhe McCrory, Chris-Anne McKenzie, Declan King, Colin Smith, Thomas Henry Gillingwater, Christopher M. Henstridge, Tara L. Spires‐Jones · 2018 · Acta Neuropathologica
Neurotheranostics as Personalized Medicines
Kevadiya, Bhavesh D., Ottemann, Brendan M., Thomas, Midhun Ben, Mukadam, Insiya, Nigam, Saumya, McMillan, JoEllyn, Gorantla, Santhi, Bronich, Tatiana K., Edagwa, Benson, Gendelman, Howard E. · 2019 · Advanced Drug Delivery Reviews
Small RNA sequencing revealed dysregulated piRNAs in Alzheimer's disease and their probable role in pathogenesis
Roy, Jyoti, Sarkar, Arijita, Parida, Sibun, Ghosh, Zhumur, Mallick, Bibekanand · 2017 · Molecular BioSystems
Interaction between pathogenic proteins in neurodegenerative disorders
K. A. Jellinger · 2011 · Journal of Cellular and Molecular Medicine
Olfactory discrimination predicts cognitive decline among community-dwelling older adults
Hamid Reza Sohrabi, Kristyn Alissa Bates, Michael Weinborn, Amy N.B. Johnston, Amitice Bahramian, Kevin Taddei, Simon Matthew Laws, Mark A. Rodrigues, Michael Morici, M Howard et al. · 2012 · Translational Psychiatry
Tau Antibody Targeting Pathological Species Blocks Neuronal Uptake and Interneuron Propagation of Tau in Vitro
Nobuhara, Chloe K., DeVos, Sarah L., Commins, Caitlin, Wegmann, Susanne, Moore, Benjamin D., Roe, Allyson D., Costantino, Isabel, Frosch, Matthew P., Pitstick, Rose, Carlson, George A. et al. · 2017 · The American Journal of Pathology
Neuroprotective role of astaxanthin in hippocampal insulin resistance induced by Aβ peptides in animal model of Alzheimer’s disease
Syed Obaidur Rahman, Bibhu Prasad Panda, Suhel Parvez, Madhu Kaundal, Salman Hussain, Mohd Akhtar, Abul Kalam Najmi · 2018 · Biomedicine & Pharmacotherapy
Blood-brain barrier integrity in the pathogenesis of Alzheimer’s disease
Zhangsen Huang, Lik‐Wei Wong, Yixun Su, Xiaomin Huang, Nan Wang, Hui Chen, Chenju Yi · 2020 · Frontiers in Neuroendocrinology
In vivo rate-determining steps of tau seed accumulation in Alzheimer’s disease
Meisl, Georg, Hidari, Eric, Allinson, Kieren, Rittman, Timothy, DeVos, Sarah L., Sanchez, Justin S., Xu, Catherine K., Duff, Karen E., Johnson, Keith A., Rowe, James B. et al. · 2021 · Science Advances
Characterization of the 18 kDa translocator protein (TSPO) expression in post‐mortem normal and Alzheimer's disease brains
Gui, Yaxing, Marks, Jordan D., Das, Sudeshna, Hyman, Bradley T., Serrano‐Pozo, Alberto · 2020 · Brain Pathology
G-Protein-Coupled Receptors in CNS: A Potential Therapeutic Target for Intervention in Neurodegenerative Disorders and Associated Cognitive Deficits
Shofiul Azam, Md. Ezazul Haque, Md. Jakaria, Song-Hee Jo, In‐Su Kim, Dong‐Kug Choi · 2020 · Cells
Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease
Shi-Yu Chen, Yue Gao, Jiayi Sun, Xianli Meng, Dong Yang, Linhong Fan, Xiang Li, Ping Wang · 2020 · Frontiers in Pharmacology
Genetic architecture of Alzheimer's disease
Neuner, Sarah M., TCW, Julia, Goate, Alison M. · 2020 · Neurobiology of Disease
ABCA7 and Pathogenic Pathways of Alzheimer’s Disease
Tomonori Aikawa, Marie‐Louise Holm, Takahisa Kanekiyo · 2018 · Brain Sciences
Analysis of brain sub regions using optimization techniques and deep learning method in Alzheimer disease
D. Chitradevi, S. Prabha · 2019 · Applied Soft Computing
Cortical atrophy in patients with cerebral amyloid angiopathy: a case-control study
Fotiadis, Panagiotis, van Rooden, Sanneke, van der Grond, Jeroen, Schultz, Aaron, Martinez-Ramirez, Sergi, Auriel, Eitan, Reijmer, Yael, van Opstal, Anna M, Ayres, Alison, Schwab, Kristin M et al. · 2016 · The Lancet Neurology
From cellular senescence to Alzheimer’s disease: The role of telomere shortening
Boccardi, Virginia, Pelini, Luca, Ercolani, Sara, Ruggiero, Carmelinda, Mecocci, Patrizia · 2015 · Ageing Research Reviews
Targeting Oxidative Stress Mechanisms to Treat Alzheimer’s and Parkinson’s Disease: A Critical Review
Aborode, Abdullahi Tunde, Pustake, Manas, Awuah, Wireko Andrew, Alwerdani, Mariam, Shah, Parth, Yarlagadda, Rohan, Ahmad, Shahzaib, Silva Correia, Inês F., Chandra, Ayush, Nansubuga, Esther Patience et al. · 2022 · Oxidative Medicine and Cellular Longevity
Microglia in Alzheimer’s Disease in the Context of Tau Pathology
Juan Ramón Perea, Marta Bolós, Jesús Ávila · 2020 · Biomolecules
The Role of Vitamins in Neurodegenerative Disease: An Update
Sachchida Nand, Payal Singh, Harry W.M. Steinbusch, Emanuel Vamanu, Ghulam Md Ashraf, Mohan Prasad Singh · 2021 · Biomedicines
Traumatic brain injury history is associated with an earlier age of dementia onset in autopsy-confirmed Alzheimer’s disease.
Schaffert, Jeff, LoBue, Christian, White, Charles L., Chiang, Hsueh-Sheng, Didehbani, Nyaz, Lacritz, Laura, Rossetti, Heidi, Dieppa, Marisara, Hart, John, Cullum, C. Munro · 2018 · Neuropsychology
Molecular regulation of dendritic spine dynamics and their potential impact on synaptic plasticity and neurological diseases
Panchanan Maiti, Jayeeta Manna, G. Ilavazhagan, Julien Rossignol, Gary Leo Dunbar · 2015 · Neuroscience & Biobehavioral Reviews
PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation
Juan Manuel Zolezzi, Manuel J. Santos, Sussy Bastias Candia, Claudio Pinto, Juan Alejandro Godoy, Nibaldo C. Inestrosa · 2017 · Biological reviews/Biological reviews of the Cambridge Philosophical Society
Multi-Omics Analysis of Microglial Extracellular Vesicles From Human Alzheimer’s Disease Brain Tissue Reveals Disease-Associated Signatures
Whitaker Cohn, Mikhail Melnik, Calvin Huang, Bruce Teter, Sujyoti Chandra, Chunni Zhu, Laura Beth McIntire, Varghese John, Karen H. Gylys, Tina V. Bilousova · 2021 · Frontiers in Pharmacology
Monoclonal Antibodies against Aβ42 Fibrils Distinguish Multiple Aggregation State Polymorphisms in Vitro and in Alzheimer Disease Brain
Asa Hatami, Ricardo Albay, Sanaz Monjazeb, Saskia C. F. Milton, Charles G. Glabe · 2014 · Journal of Biological Chemistry
Green synthesized cerium oxide nanoparticle: A prospective drug against oxidative harm
Debanjan Dutta, Riya Mukherjee, Mousumi Patra, Milon Banik, Rakhi Dasgupta, M. Mukherjee, Tarakdas Basu · 2016 · Colloids and Surfaces B Biointerfaces
Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease
Adam R. Smith, Rebecca G. Smith, Ehsan Pishva, Eilis J. Hannon, Janou A. Y. Roubroeks, Joe Burrage, Claire Troakes, Safa Al‐Sarraj, Carolyn Sloan, Jonathan S. Mill et al. · 2019 · Clinical Epigenetics
Future Therapeutic Perspectives into the Alzheimer’s Disease Targeting the Oxidative Stress Hypothesis
Jéssika Poliana Teixeira, Alexandre Alves de Castro, Flávia V. Soares, Elaine F. F. da Cunha, Teodorico C. Ramalho · 2019 · Molecules
Iatrogenic Creutzfeldt-Jakob disease with Amyloid-β pathology: an international study
Ignazio Calì, Mark L. Cohen, Stéphane Haı̈k, Piero Parchi, Giorgio Giaccone, Steven John Collins, Diane Kofskey, Han Wang, Catriona McLean, Jean‐Philippe Brandel et al. · 2018 · Acta Neuropathologica Communications
The role of innate immunity in Alzheimer's disease
Hannah E. Ennerfelt, John R. Lukens · 2020 · Immunological Reviews
Mitochondrial Ca2+ Signaling in Health, Disease and Therapy
Lorenzo Modesti, Alberto Danese, Veronica Angela Maria Vitto, Daniela Ramaccini, Gianluca Aguiari, Roberta Gafà, Giovanni Lanza, Carlotta Giorgi, Paolo Pinton · 2021 · Cells
Is synaptic loss a unique hallmark of Alzheimer’s disease?
Scheff, Stephen W., Neltner, Janna H., Nelson, Peter T. · 2014 · Biochemical Pharmacology
Hyperphosphorylated tau mediates neuronal death by inducing necroptosis and inflammation in Alzheimer’s disease
Yue Dong, Hanqiao Yu, Xueqi Li, Kelong Bian, Yayuan Zheng, Mingrui Dai, Xuejian Feng, Yao Sun, Yu Ting He, Bin Yu et al. · 2022 · Journal of Neuroinflammation
Microglia prevent peripheral immune cell invasion and promote an anti-inflammatory environment in the brain of APP-PS1 transgenic mice
Michael Stefan Unger, P. Schernthaner, Julia Marschallinger, Heike Mrowetz, Ludwig Aigner · 2018 · Journal of Neuroinflammation
Longitudinal 18F-MK-6240 tau tangles accumulation follows Braak stages
Tharick Ali Pascoal, Andréa Lessa Benedet, Dana Tudorascu, Joseph Therriault, Sulantha Sanjeewa Mathotaarachchi, Mélissa Savard, Firoza Zubeida Lussier, Cécile Tissot, Mira Chamoun, Min Su Kang et al. · 2021 · Brain
Alzheimer's disease pathology is attenuated in a CD 38‐deficient mouse model
Blacher, Eran, Dadali, Tulin, Bespalko, Alina, Haupenthal, Viola J., Grimm, Marcus O. W., Hartmann, Tobias, Lund, Frances E., Stein, Reuven, Levy, Ayelet · 2015 · Annals of Neurology
The Many Faces of Astrocytes in Alzheimer's Disease
Monterey, Michael D., Wei, Haichao, Wu, Xizi, Wu, Jia Qian · 2021 · Frontiers in Neurology
Neurodegeneration and Alzheimer's disease (AD). What Can Proteomics Tell Us About the Alzheimer's Brain?
Guillermo Moya‐Alvarado, Noga Gershoni‐Emek, Eran Perlson, Francisca C. Bronfman · 2016 · Molecular & Cellular Proteomics
Synaptic Dysfunction in Alzheimer’s Disease: Aβ, Tau, and Epigenetic Alterations
Ke Li, Qing Wei, Fangfang Liu, Fan Hu, Ao‐Ji Xie, Ling‐Qiang Zhu, Dan Liu · 2017 · Molecular Neurobiology
Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning
Md. Tanvir Kabir, Md. Sahab Uddin, Mst. Marium Begum, Shanmugam Thangapandiyan, Md. Sohanur Rahman, Lotfi Aleya, Bijo Mathew, Muniruddin Ahmed, George Emilio Barreto, Ghulam Md Ashraf · 2019 · Current Pharmaceutical Design
Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2) and Mitochondrial Dynamics/Mitophagy in Neurological Diseases
Tae‐Cheon Kang · 2020 · Antioxidants
Mitochondrial permeability transition pore: a potential drug target for neurodegeneration
Komal Kalani, Shi Fang Yan, Shirley ShiDu Yan · 2018 · Drug Discovery Today
Neuropathogenesis-on-chips for neurodegenerative diseases
Sarnai Amartumur, Huong Mai Nguyen, Thuy Huynh, Testaverde S. Kim, Ran‐Sook Woo, Eungseok Oh, Kyeong Kyu Kim, Luke P. Lee, Chaejeong Heo · 2024 · Nature Communications
Interplay between protein glycosylation pathways in Alzheimer’s disease
Moran Frenkel‐Pinter, Merav D. Shmueli, Chen Raz, Michaela Yanku, Shai Zilberzwige‐Tal, Ehud Gazit, Daniel Segal · 2017 · Science Advances
Different Force Fields Give Rise to Different Amyloid Aggregation Pathways in Molecular Dynamics Simulations
Suman Samantray, Feng Yin, Batuhan Kav, Birgit Strodel · 2020 · Journal of Chemical Information and Modeling