The DOI matches its Crossref record; 156 of the 156 references it cites were found in a registry or an index.
Non-Smad Signaling Pathways of the TGF-β Family
Open accessAbstract
Transforming growth factor β (TGF-β) and structurally related factors use several intracellular signaling pathways in addition to Smad signaling to regulate a wide array of cellular functions. These non-Smad signaling pathways are activated directly by ligand-occupied receptors to reinforce, attenuate, or otherwise modulate downstream cellular responses. This review summarizes the current knowledge of the mechanisms by which non-Smad signaling pathways are directly activated in response to ligand binding, how activation of these pathways impinges on Smads and non-Smad targets, and how final cellular responses are affected in response to these noncanonical signaling modes.
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Cites
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Metadata
- Authors
- Zhang, Y. E.
- Venue
- Cold Spring Harbor Perspectives in Biology
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2016-11-18
- Volume
- 9
- Issue
- 2
- Pages
- a022129
- ISSN
- 1943-0264 (ISSN-L)
- OpenAlex
- W2551413444
- Cited by
- 697
- References
- 156
- Type
- posted content
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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