p53 in the DNA–Damage–Repair Process

WAF1, a potential mediator of p53 tumor suppression

El-Deiry, W. S., Tokino, T., Velculescu, V. E., Levy, D. B., Parsons, R., Trent, J. M., Lin, D., Mercer, W. E., Kinzler, K. W., & Vogelstein, B. (1993) · Cell · doi:10.1016/0092-8674(93)90500-p · Cited by 8,321 · see citing works

The ATM protein kinase: regulating the cellular response to genotoxic stress, and more

Shiloh, Y., & Ziv, Y. (2013) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3546 · Cited by 1,649 · see citing works

Understanding nucleotide excision repair and its roles in cancer and ageing

Marteijn, J. A., Lans, H., Vermeulen, W., & Hoeijmakers, J. H. J. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3822 · Cited by 1,192 · see citing works

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles

Yin, Y., Tainsky, M. A., Bischoff, F. Z., Strong, L. C., & Wahl, G. M. (1992) · Cell · doi:10.1016/0092-8674(92)90244-7 · Cited by 1,089 · see citing works

Repair of Strand Breaks by Homologous RecombinationPreprint

Jasin, M., & Rothstein, R. J. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012740 · Cited by 877 · see citing works

A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis

Gao, Y., Sun, Y., Frank, K. M., Dikkes, P., Fujiwara, Y., Seidl, K. J., Sekiguchi, J. M., Rathbun, G. A., Swat, W., Wang, J., et al. (1998) · Cell · doi:10.1016/s0092-8674(00)81714-6 · Cited by 688 · see citing works

Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development

Gao, Y., Ferguson, D., Xie, W., Manis, J., Sekiguchi, J., Frank, K., Chaudhuri, J., Horner, J., DePinho, R., & Alt, F. (2000) · Nature · doi:10.1038/35009138 · Cited by 608 · see citing works

Expression of the <i>p48</i> xeroderma pigmentosum gene is p53-dependent and is involved in global genomic repair

Hwang, B. J., Ford, J. M., Hanawalt, P. C., & Chu, G. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.2.424 · Cited by 581 · see citing works

p53 modulation of TFIIH–associated nucleotide excision repair activity

Wang, X. W., Yeh, H., Schaeffer, L., Roy, R., Moncollin, V., Egly, J., Wang, Z., Friedberg, E. C., Evans, M. K., Taffe, B. G., et al. (1995) · Nature Genetics · doi:10.1038/ng0695-188 · Cited by 550 · see citing works

p53: traffic cop at the crossroads of DNA repair and recombination

Sengupta, S., & Harris, C. C. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1546 · Cited by 544 · see citing works

Human RecQ Helicases in DNA Repair, Recombination, and Replication

Croteau, D. L., Popuri, V., Opresko, P. L., & Bohr, V. A. (2014) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060713-035428 · Cited by 535 · see citing works

A Conserved Checkpoint Pathway Mediates DNA Damage–Induced Apoptosis and Cell Cycle Arrest in C. elegans

Gartner, A., Milstein, S., Ahmed, S. C., Hodgkin, J., & Hengartner, M. O. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80438-4 · Cited by 513 · see citing works

DNA Ligase IV Deficiency in Mice Leads to Defective Neurogenesis and Embryonic Lethality via the p53 Pathway

Frank, K. M., Sharpless, N. E., Gao, Y., Sekiguchi, J., Ferguson, D. O., Zhu, C., Manis, J. P., Horner, J. W., DePinho, R. A., & Alt, F. W. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80264-6 · Cited by 492 · see citing works

Identification of redox/repair protein Ref-1 as a potent activator of p53.Preprint

Jayaraman, L., Murthy, K. G. K., Zhu, C., Curran, T., Xanthoudakis, S., & Prives, C. L. (1997) · Genes & Development · doi:10.1101/gad.11.5.558 · Cited by 479 · see citing works

Caenorhabditis elegans p53: Role in Apoptosis, Meiosis, and Stress Resistance

Derry, W. B., Putzke, A. P., & Rothman, J. H. (2001) · Science · doi:10.1126/science.1065486 · Cited by 464 · see citing works

Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage

Deriano, L., & Roth, D. B. (2013) · Annual Review of Genetics · doi:10.1146/annurev-genet-110711-155540 · Cited by 448 · see citing works

Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?

Bétermier, M., Bertrand, P., & López, B. S. (2014) · PLoS Genetics · doi:10.1371/journal.pgen.1004086 · Cited by 420 · see citing works

p53 and its 14 kDa C-terminal domain recognize primary DNA damage in the form of insertion/deletion mismatches

Lee, S., Elenbaas, B., Levine, A. J., & Griffith, J. D. (1995) · Cell · doi:10.1016/s0092-8674(05)80006-6 · Cited by 405 · see citing works

Involvement of the p53 tumor suppressor in repair of u.v.-type DNA damage.

Smith, M. L., Chen, I. T., Zhan, Q., O'Connor, P. M., & Fornace, A. J. (1995) · PubMed · Cited by 364 · see citing works

Expression of Wild-type p53 Is Required for Efficient Global Genomic Nucleotide Excision Repair in UV-irradiated Human Fibroblasts

Ford, J. M., & Hanawalt, P. C. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.44.28073 · Cited by 357 · see citing works

The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

Schumacher, B., Hofmann, K., Boulton, S. J., & Gartner, A. (2001) · Current Biology · doi:10.1016/s0960-9822(01)00534-6 · Cited by 355 · see citing works

Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance.

Ford, J. M., & Hanawalt, P. C. (1995) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.92.19.8876 · Cited by 343 · see citing works

A role for p53 in base excision repair

Zhou, J., Ahn, J., Wilson, S. H., & Prives, C. (2001) · The EMBO Journal · doi:10.1093/emboj/20.4.914 · Cited by 333 · see citing works

p53 and DNA damage-inducible expression of the xeroderma pigmentosum group C gene

Adimoolam, S., & Ford, J. M. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.202485699 · Cited by 321 · see citing works

Selenomethionine regulation of p53 by a ref1-dependent redox mechanism

Seo, Y. R., Kelley, M. R., & Smith, M. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.212319799 · Cited by 280 · see citing works

Caenorhabditis elegans HUS-1 Is a DNA Damage Checkpoint Protein Required for Genome Stability and EGL-1-Mediated Apoptosis

Hofmann, E. R., Milstein, S., Boulton, S. J., Ye, M., Hofmann, J., Stergiou, L., Gartner, A., Vidal, M., & Hengartner, M. O. (2002) · Current Biology · doi:10.1016/s0960-9822(02)01262-9 · Cited by 280 · see citing works

V(D)J recombination activates a p53-dependent DNA damage checkpoint in scid lymphocyte precursors.Preprint

Guidos, C. J., Williams, C. J., Grandal, I., Knowles, G. C., Huang, M. T. F., & Danska, J. S. (1996) · Genes & Development · doi:10.1101/gad.10.16.2038 · Cited by 272 · see citing works

Ref‐1 regulates the transactivation and pro‐apoptotic functions of p53 in vivo

Gaiddon, C., Moorthy, N. C., & Prives, C. (1999) · The EMBO Journal · doi:10.1093/emboj/18.20.5609 · Cited by 244 · see citing works

p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage

Rubbi, C. P., & Milner, J. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg082 · Cited by 229 · see citing works

Evidence for Replicative Repair of DNA Double-Strand Breaks Leading to Oncogenic Translocation and Gene Amplification

Difilippantonio, M. J., Petersen, S., Chen, H. T., Johnson, R., Jasin, M., Kanaar, R., Ried, T., & Nussenzweig, A. (2002) · The Journal of Experimental Medicine · doi:10.1084/jem.20020851 · Cited by 225 · see citing works

Translational Repression of C. elegans p53 by GLD-1 Regulates DNA Damage-Induced Apoptosis

Schumacher, B., Hanazawa, M., Lee, M., Nayak, S., Volkmann, K., Hofmann, R., Hengartner, M. O., Schedl, T., & Gartner, A. (2005) · Cell · doi:10.1016/j.cell.2004.12.009 · Cited by 214 · see citing works

BLM helicase‐dependent transport of p53 to sites of stalled DNA replication forks modulates homologous recombination

Sengupta, S., Linke, S. P., Pedeux, R., Yang, Q., Farnsworth, J., Garfield, S. H., Valerie, K. C., Shay, J. W., Ellis, N. A., Wasylyk, B., et al. (2003) · The EMBO Journal · doi:10.1093/emboj/cdg114 · Cited by 210 · see citing works

p53 modulates homologous recombination by transcriptional regulation of the RAD51 gene

Arias, C., Lazaro‐Trueba, I., Kerr, P., Lord, C. J., Dexter, T., Iravani, M., Ashworth, A., & Silva, A. (2005) · EMBO Reports · doi:10.1038/sj.embor.7400587 · Cited by 206 · see citing works

Mutations in the <i>WRN</i> Gene in Mice Accelerate Mortality in a p53-Null Background

Lombard, D. B., Beard, C., Johnson, B., Marciniak, R. A., Dausman, J., Bronson, R., Buhlmann, J. E., Lipman, R., Curry, R., Sharpe, A., et al. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.9.3286-3291.2000 · Cited by 187 · see citing works

C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage

Schumacher, B., Schertel, C., Wittenburg, N., Tuck, S., Mitani, S., Gartner, A., Conradt, B., & Shaham, S. (2004) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401539 · Cited by 186 · see citing works

Role of p53 in Sensing Oxidative DNA Damage in Response to Reactive Oxygen Species-Generating Agents

Achanta, G., & Huang, P. (2004) · Cancer Research · doi:10.1158/0008-5472.can-04-0494 · Cited by 184 · see citing works

p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA binding

Liu, Y. (2001) · Carcinogenesis · doi:10.1093/carcin/22.6.851 · Cited by 183 · see citing works

Physical and Functional Interaction between p53 and the Werner's Syndrome Protein

Blander, G., Kipnis, J., Martínez-Leal, J. F., Yu, C., Schellenberg, G. D., & Oren, M. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.41.29463 · Cited by 181 · see citing works

p53-Mediated apoptosis is attenuated in Werner syndrome cellsPreprint

Spillare, E. A., Robles, A. I., Wang, X. W., Shen, J.-C., Yu, C., Schellenberg, G. D., & Harris, C. C. (1999) · Genes & Development · doi:10.1101/gad.13.11.1355 · Cited by 178 · see citing works

p53 interacts with hRAD51 and hRAD54, and directly modulates homologous recombination.

Linke, S. P., Sengupta, S., Khabie, N., Jeffries, B. A., Buchhop, S., Miska, S., Henning, W., Pedeux, R., Wang, X. W., Hofseth, L. J., et al. (2003) · PubMed · Cited by 178 · see citing works

DNA Substrate Dependence of p53-Mediated Regulation of Double-Strand Break Repair

Akyüz, N., Boehden, G. S., Süße, S., Rimek, A., Preuß, U., Scheidtmann, K., & Wiesmüller, L. (2002) · Molecular and Cellular Biology · doi:10.1128/mcb.22.17.6306-6317.2002 · Cited by 175 · see citing works

Functional interactions between p53 and the TFIIH complex are affected by tumour‐associated mutations.

Léveillard, T., Anděra, L., Bissonnette, N., Schaeffer, L., Bracco, L. P., Egly, J., & Wasylyk, B. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00506.x · Cited by 173 · see citing works

Mutations in the p53 and SCID genes cooperate in tumorigenesis.Preprint

Nacht, M., Strasser, A., Chan, Y. R., Harris, A. W., Schlissel, M. S., Bronson, R. T., & Jacks, T. (1996) · Genes & Development · doi:10.1101/gad.10.16.2055 · Cited by 171 · see citing works

Functional Interaction of p53 and BLM DNA Helicase in Apoptosis

Wang, X. W., Tseng, A., Ellis, N. A., Spillare, E. A., Linke, S. P., Robles, A. I., Seker, H., Yang, Q., Hu, P., Beresten, S. F., et al. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103298200 · Cited by 145 · see citing works

Direct involvement of p53 in the base excision repair pathway of the DNA repair machinery

Offer, H., Wolkowicz, R., Matas, D., Blumenstein, S., Livneh, Z., & Rotter, V. (1999) · FEBS Letters · doi:10.1016/s0014-5793(99)00505-0 · Cited by 144 · see citing works

Is homologous recombination really an error-free process?

Guirouilh‐Barbat, J., Lambert, S., Bertrand, P., & López, B. S. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00175 · Cited by 142 · see citing works

The Processing of Holliday Junctions by BLM and WRN Helicases Is Regulated by p53

Yang, Q., Zhang, R., Wang, X. W., Spillare, E. A., Linke, S. P., Subramanian, D., Griffith, J. D., Li, J. L., Hickson, I. D., Shen, J., et al. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m204111200 · Cited by 136 · see citing works

Human RECQ helicases: Roles in DNA metabolism, mutagenesis and cancer biology

Monnat, R. J. (2010) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2010.10.002 · Cited by 122 · see citing works

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint

Saintigny, Y., Rouillard, D., Chaput, B., Soussi, T., & López, B. S. (1999) · Oncogene · doi:10.1038/sj.onc.1202941 · Cited by 121 · see citing works

Characterisation of the promoter region of the human DNA-repair gene Rad51.

Hasselbach, L. A., Haase, S., Fischer, D., Kolberg, H., & Stürzbecher, H. W. (2005) · PubMed · Cited by 115 · see citing works

Implication of p53 in base excision DNA repair: in vivo evidence

Seo, Y. R., Fishel, M. L., Amundson, S. A., Kelley, M. R., & Smith, M. L. (2002) · Oncogene · doi:10.1038/sj.onc.1205129 · Cited by 115 · see citing works

DNA-PK, ATM and ATR collaboratively regulate p53–RPA interaction to facilitate homologous recombination DNA repair

Serrano, M. A., Li, Z., Dangeti, M., Musich, P. R., Patrick, S., Roginskaya, M., Cartwright, B., & Zou, Y. (2012) · Oncogene · doi:10.1038/onc.2012.257 · Cited by 112 · see citing works

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage

Zaky, A., Busso, C., Izumi, T., Chattopadhyay, R., Bassiouny, A., Mitra, S., & Bhakat, K. K. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkm1173 · Cited by 111 · see citing works

p53 isoform Δ113p53/Δ133p53 promotes DNA double-strand break repair to protect cell from death and senescence in response to DNA damage

Gong, L., Gong, H., Pan, X., Chang, C., Ou, Z., Ye, S., Yin, L., Yang, L., Tao, T., Zhang, Z., et al. (2015) · Cell Research · doi:10.1038/cr.2015.22 · Cited by 110 · see citing works

RECQL4 is essential for the transport of p53 to mitochondria in normal human cells in the absence of exogenous stress

De, S., Kumari, J., Mudgal, R., Modi, P., Gupta, S., Futami, K., Goto, H., Lindor, N. M., Furuichi, Y., Mohanty, D., et al. (2012) · Journal of Cell Science · doi:10.1242/jcs.101501 · Cited by 107 · see citing works

hMSH2 Recruits ATR to DNA Damage Sites for Activation during DNA Damage-induced Apoptosis

Pabla, N., Ma, Z., McIlhatton, M. A., Fishel, R., & Dong, Z. (2011) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.210989 · Cited by 107 · see citing works

The onset of p53-dependent DNA repair or apoptosis is determined by the level of accumulated damaged DNA

Offer, H., Erez, N., Zurer, I., Tang, X., Milyavsky, M., Goldfinger, N., & Rotter, V. (2002) · Carcinogenesis · doi:10.1093/carcin/23.6.1025 · Cited by 107 · see citing works

P53 modulates the effect of loss of DNA mismatch repair on the sensitivity of human colon cancer cells to the cytotoxic and mutagenic effects of cisplatin.

Lin, X., Ramamurthi, K., Mishima, M., Kondo, A., Christen, R. D., & Howell, S. B. (2001) · PubMed · Cited by 106 · see citing works

The interaction of p53 with replication protein A mediates suppression of homologous recombination

Romanova, L. Y., Willers, H., Blagosklonny, M. V., & Powell, S. N. (2004) · Oncogene · doi:10.1038/sj.onc.1207982 · Cited by 105 · see citing works

p53 Modulates the Exonuclease Activity of Werner Syndrome Protein

Brosh, R. M., Karmakar, P., Sommers, J. A., Yang, Q., Wang, X. W., Spillare, E. A., Harris, C. C., & Bohr, V. A. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m103332200 · Cited by 104 · see citing works

Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control

Willers, H., McCarthy, E. E., Wu, B., Wunsch, H., Tang, W., Taghian, D. G., Xia, F., & Powell, S. N. (2000) · Oncogene · doi:10.1038/sj.onc.1203142 · Cited by 104 · see citing works

p53 and c-Jun Functionally Synergize in the Regulation of the DNA Repair Gene hMSH2 in Response to UV

Scherer, S. J., Maier, S. M., Seifert, M., Hanselmann, R. G., Zang, K. D., Müller‐Hermelink, H. K., Angel, P. E., Welter, C., & Schartl, M. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m006990200 · Cited by 102 · see citing works

Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells

Rooney, S., Sekiguchi, J., Whitlow, S. R., Eckersdorff, M., Manis, J. P., Lee, C., Ferguson, D. O., & Alt, F. W. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0308757101 · Cited by 102 · see citing works

Regulation of damage recognition in mammalian global genomic nucleotide excision repair

Sugasawa, K. (2009) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2009.08.004 · Cited by 99 · see citing works

p53 modulates base excision repair activity in a cell cycle-specific manner after genotoxic stress.

Offer, H., Zurer, I., Bánfalvi, G., Rehak, M., Falcovitz, A., Milyavsky, M., Goldfinger, N., & Rotter, V. (2001) · PubMed · Cited by 98 · see citing works

The DDB2 nucleotide excision repair gene product p48 enhances global genomic repair in p53 deficient human fibroblasts

Fitch, M. E., Cross, I. V., Turner, S. J., Adimoolam, S., Lin, C., Williams, K. G., & Ford, J. M. (2003) · DNA repair · doi:10.1016/s1568-7864(03)00066-1 · Cited by 96 · see citing works

Genetic pathway to recurrent chromosome translocations in murine lymphoma involves V(D)J recombinase

Vanasse, G. J., Halbrook, J., Thomas, S., Burgess, A., Hoekstra, M. F., Distèche, C. M., & Willerford, D. M. (1999) · Journal of Clinical Investigation · doi:10.1172/jci6658 · Cited by 89 · see citing works

The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice

Gladdy, R. A., Taylor, M. D., Williams, C. J., Grandal, I., Karásková, J., Squire, J. A., Rutka, J. T., Guidos, C. J., & Danska, J. S. (2003) · Cancer Cell · doi:10.1016/s1535-6108(02)00236-2 · Cited by 84 · see citing works

Tumor suppressor p53 represses transcription of RECQ4 helicase

Sengupta, S., Shimamoto, A., Koshiji, M., Pedeux, R., Rusin, M., Spillare, E. A., Shen, J., Huang, E. L., Lindor, N. M., Furuichi, Y., et al. (2005) · Oncogene · doi:10.1038/sj.onc.1208380 · Cited by 80 · see citing works

ATM-Mediated Stabilization of hMutL DNA Mismatch Repair Proteins Augments p53 Activation during DNA Damage

Luo, Y., Lin, F., & Lin, W.-C. (2004) · Molecular and Cellular Biology · doi:10.1128/mcb.24.14.6430-6444.2004 · Cited by 79 · see citing works

p53 responsive nucleotide excision repair gene products p48 and XPC, but not p53, localize to sites of UV-irradiation-induced DNA damage, in vivo

Fitch, M. E. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg031 · Cited by 79 · see citing works

Structural and functional involvement of p53 in BER in vitro and in vivo

Offer, H., Milyavsky, M., Erez, N., Matas, D., Zurer, I., Harris, C. C., & Rotter, V. (2001) · Oncogene · doi:10.1038/sj.onc.1204120 · Cited by 73 · see citing works

The role of p53 in base excision repair following genotoxic stress

Zurer, I. (2003) · Carcinogenesis · doi:10.1093/carcin/bgg186 · Cited by 72 · see citing works

Female embryonic lethality in mice nullizygous for both Msh2 and p53

Cranston, A. N., Bocker, T., Reitmair, A. H., Palazzo, J., Wilson, T., Mak, T. W., & Fishel, R. A. (1997) · Nature Genetics · doi:10.1038/ng0997-114 · Cited by 71 · see citing works

Redox factor 1 (Ref-1) enhances specific DNA binding of p53 by promoting p53 tetramerization

Hanson, S., Kim, E., & Deppert, W. (2005) · Oncogene · doi:10.1038/sj.onc.1208351 · Cited by 70 · see citing works

Regulation of developmental rate and germ cell proliferation in Caenorhabditis elegans by the p53 gene network

Derry, W. B., Bierings, R., van Iersel, M., Satkunendran, T., Reinke, V., & Rothman, J. H. (2006) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4402075 · Cited by 69 · see citing works

Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.

Wani, M. A., Zhu, Q., El-Mahdy, M. A., Venkatachalam, S., & Wani, A. A. (2000) · PubMed · Cited by 63 · see citing works

RECQL4 and p53 potentiate the activity of polymerase γ and maintain the integrity of the human mitochondrial genome

Gupta, S., De, S., Srivastava, V. K., Hussain, M., Kumari, J., Muniyappa, K., & Sengupta, S. (2013) · Carcinogenesis · doi:10.1093/carcin/bgt315 · Cited by 62 · see citing works

MUTYH, an adenine DNA glycosylase, mediates p53 tumor suppression via PARP-dependent cell death

Oka, S., Leon, J., Tsuchimoto, D., Sakumi, K., & Nakabeppu, Y. (2014) · Oncogenesis · doi:10.1038/oncsis.2014.35 · Cited by 58 · see citing works

Decreased DNA Repair Efficiency by Loss or Disruption of p53 Function Preferentially Affects Removal of Cyclobutane Pyrimidine Dimers from Non-transcribed Strand and Slow Repair Sites in Transcribed Strand

Zhu, Q., Wani, M. A., El-Mahdy, M. A., & Wani, A. A. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.275.15.11492 · Cited by 58 · see citing works

Association of p53 and MSH2 with recombinative repair complexes during S phase

Zink, D., Mayr, C., Janz, C., & Wiesmüller, L. (2002) · Oncogene · doi:10.1038/sj.onc.1205614 · Cited by 56 · see citing works

UV wavelength-dependent regulation of transcription-coupled nucleotide excision repair in p53-deficient human cells

Mathonnet, G., Léger, C., Desnoyers, J., Drouin, R., Therrien, J., & Drobetsky, E. A. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1232161100 · Cited by 56 · see citing works

The effect of p53‐RNAi and p53 knockout on human 8‐oxoguanine DNA glycosylase (hOgg1) activity

Chatterjee, A., Mambo, E., Osada, M., Upadhyay, S. K., & Sidransky, D. (2005) · The FASEB Journal · doi:10.1096/fj.04-3423fje · Cited by 55 · see citing works

Interaction of Werner and Bloom syndrome genes with p53 in familial breast cancer

Wirtenberger, M. (2005) · Carcinogenesis · doi:10.1093/carcin/bgi374 · Cited by 54 · see citing works

Faculty DNA polymerase δ/ɛ-mediated excision repair in response to γ radiation or ultraviolet light in p53-deficient fibroblast strains from affected members of a cancer-prone family with Li-Fraumeni syndrome

Mirzayans, R., Enns, L., Dietrich, K. D., et al. (1996) · Carcinogenesis · doi:10.1093/carcin/17.4.691 · Cited by 52 · see citing works

The Werner syndrome protein contributes to induction of p53 by DNA damage

Blander, G., Zalle, N., Martínez-Leal, J. F., Bar‐Or, R. L., Yu, C., & Oren, M. (2000) · The FASEB Journal · doi:10.1096/fj.00-0171fje · Cited by 49 · see citing works

Interactions between p53, hMSH2-hMSH6 and HMG I(Y) on Holliday junctions and bulged bases

Subramanian, D. (2002) · Nucleic Acids Research · doi:10.1093/nar/30.11.2427 · Cited by 47 · see citing works

The MutSβ complex is a modulator of p53-driven tumorigenesis through its functions in both DNA double-strand break repair and mismatch repair

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Cellular Responses to DNA Damage

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