The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
MicroRNAs in plants
Open accessAbstract
MicroRNAs (miRNAs) are an extensive class of ∼22-nucleotide noncoding RNAs thought to regulate gene expression in metazoans. We find that miRNAs are also present in plants, indicating that this class of noncoding RNA arose early in eukaryotic evolution. In this paper 16 Arabidopsis miRNAs are described, many of which have differential expression patterns in development. Eight are absolutely conserved in the rice genome. The plant miRNA loci potentially encode stem–loop precursors similar to those processed by Dicer (a ribonuclease III) in animals. Mutation of an Arabidopsis Dicer homolog, CARPEL FACTORY, prevents the accumulation of miRNAs, showing that similar mechanisms direct miRNA processing in plants and animals. The previously described roles of CARPEL FACTORY in the development of Arabidopsis embryos, leaves, and floral meristems suggest that the miRNAs could play regulatory roles in the development of plants as well as animals.
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Cites
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Cited by
Bartel (2004) · doi:10.1016/s0092-8674(04)00045-5 · Cited by 34,714
MicroRNAs: small RNAs with a big role in gene regulation
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Real-time quantification of microRNAs by stem-loop RT-PCR
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Asymmetry in the Assembly of the RNAi Enzyme Complex
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Metadata
- Authors
- Reinhart, B. J., Weinstein, E. G., Rhoades, M. W., Bartel, B., & Bartel, D. P.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2002-07-01
- Volume
- 16
- Issue
- 13
- Pages
- 1616-1626
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W4212941976
- Cited by
- 1,948
- References
- 8
- Type
- posted content
- Language
- en
- Open access
- diamond
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