Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration
Open accessAbstract
Syndecan-3 and syndecan-4 function as coreceptors for tyrosine kinases and in cell adhesion. Syndecan-3-/- mice exhibit a novel form of muscular dystrophy characterized by impaired locomotion, fibrosis, and hyperplasia of myonuclei and satellite cells. Explanted syndecan-3-/- satellite cells mislocalize MyoD, differentiate aberrantly, and exhibit a general increase in overall tyrosine phosphorylation. Following induced regeneration, the hyperplastic phenotype is recapitulated. While there are fewer apparent defects in syndecan-4-/- muscle, explanted satellite cells are deficient in activation, proliferation, MyoD expression, myotube fusion, and differentiation. Further, syndecan-4-/- satellite cells fail to reconstitute damaged muscle, suggesting a unique requirement for syndecan-4 in satellite cell function.
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Skeletal muscle has substantial regenerative capacity because of adult muscle stem cells, also called satellite cells, which are important for postnatal muscle growth and repair.
“skeletal muscle harbors considerable regenerative capacity due to the presence of adult muscle stem cells (MuSC), also known as satellite cells, which play a major role in postnatal muscle growth and repair (Collins et al., 2005; Cornelison et al., 2004; Kuang et al., 2007; Montarras et al., 2005; Sacco et al., 2008).”
From Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice (2010) · cites this paper as Cornelison et al., 2004
Sdc4 is expressed in SCs and is required for SC activation.
“Syndecan-4 (Sdc4) is expressed in SCs and is required for SC activation21,22, but a role for Sdc4 in myofibers remains elusive.”
From In vivo partial reprogramming of myofibers promotes muscle regeneration by remodeling the stem cell niche (2021) · cites this paper as [22]
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Myogenic satellite cells: physiology to molecular biology
Hawke, T. J., & Garry, D. J. (2001) · Journal of Applied Physiology · doi:10.1152/jappl.2001.91.2.534 · Cited by 1,646 · see citing works
Cornelison, D., & Wold, B. J. (1997) · Developmental Biology · doi:10.1006/dbio.1997.8721 · Cited by 934 · see citing works
Self-citationSyndecans: multifunctional cell-surface co-receptors
Carey, D. J. (1997) · Biochemical Journal · doi:10.1042/bj3270001 · Cited by 687 · see citing works
HGF/SF Is Present in Normal Adult Skeletal Muscle and Is Capable of Activating Satellite Cells
Tatsumi, R., Anderson, J. E., Nevoret, C. J., Halevy, O., & Allen, R. E. (1998) · Developmental Biology · doi:10.1006/dbio.1997.8803 · Cited by 685 · see citing works
A New Look at the Origin, Function, and “Stem-Cell” Status of Muscle Satellite Cells
Seale, P., & Rudnicki, M. A. (2000) · Developmental Biology · doi:10.1006/dbio.1999.9565 · Cited by 590 · see citing works
Skeletal muscle satellite cells
Schultz, E., & McCormick, K. M. (1994) · Reviews of physiology, biochemistry and pharmacology · doi:10.1007/bfb0030904 · Cited by 526 · see citing works
Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4
Echtermeyer, F. G., Streit, M., Wilcox‐Adelman, S. A., Saoncella, S., Denhez, F., Detmar, M. J., & Goetinck, P. F. (2001) · Journal of Clinical Investigation · doi:10.1172/jci10559 · Cited by 427 · see citing works
Self-citationHepatocyte growth factor activates quiescent skeletal muscle satellite cells in vitro
Allen, R. E., Sheehan, S. M., Taylor, R. G., Kendall, T. L., & Rice, G. M. (1995) · Journal of Cellular Physiology · doi:10.1002/jcp.1041650211 · Cited by 422 · see citing works
Cornelison, D., Filla, M. S., Stanley, H. M., Rapraeger, A. C., & Olwin, B. B. (2001) · Developmental Biology · doi:10.1006/dbio.2001.0416 · Cited by 399 · see citing works
Self-citationMyoD−/− Satellite Cells in Single-Fiber Culture Are Differentiation Defective and MRF4 Deficient
Cornelison, D., Olwin, B. B., Rudnicki, M. A., & Wold, B. J. (2000) · Developmental Biology · doi:10.1006/dbio.2000.9682 · Cited by 314 · see citing works
Self-citationThe syndecans, tuners of transmembrane signaling
Zimmermann, P., & David, G. (1999) · The FASEB Journal · doi:10.1096/fasebj.13.9001.s91 · Cited by 216 · see citing works
Reizes, O., Lincecum, J. M., Wang, Z., Goldberger, O., Huang, L., Kaksonen, M., Ahima, R. S., Hinkes, M. T., Barsh, G. S., Rauvala, H., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00415-9 · Cited by 212 · see citing works
Self-citationSyndecan-Regulated Receptor Signaling
Rapraeger, A. C. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.5.995 · Cited by 197 · see citing works
Self-citationSyndecan-3-Deficient Mice Exhibit Enhanced LTP and Impaired Hippocampus-Dependent Memory
Kaksonen, M., Pavlov, I., Võikar, V., Lauri, S. E., Hienola, A., Riekki, R., Lakso, M., Taira, T., & Rauvala, H. (2002) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.2002.1167 · Cited by 158 · see citing works
Self-citationSyndecan-4 Modulates Focal Adhesion Kinase Phosphorylation
Wilcox‐Adelman, S. A., Denhez, F., & Goetinck, P. F. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m201283200 · Cited by 142 · see citing works
Self-citationRole of the basement membrane in the regeneration of skeletal muscle
Caldwell, C., Mattey, D. L., & Weller, R. (1990) · Neuropathology and Applied Neurobiology · doi:10.1111/j.1365-2990.1990.tb01159.x · Cited by 115 · see citing works
Functional characteristics of dystrophic skeletal muscle: insights from animal models
Watchko, J. F., O’Day, T. L., & Hoffman, E. P. (2002) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01242.2001 · Cited by 111 · see citing works
Syndecan-1 Expression Is Down-regulated during Myoblast Terminal Differentiation
Larraı́n, J., Cizmeci-Smith, G., Troncoso, V., Stahl, R. C., Carey, D. J., & Brandan, E. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.29.18418 · Cited by 84 · see citing works
Expression and localization of proteoglycans during limb myogenic activation
Olguín, H. C., & Brandan, E. (2001) · Developmental Dynamics · doi:10.1002/dvdy.1129 · Cited by 40 · see citing works
Flagged first, then by citations
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Satellite Cells and the Muscle Stem Cell Niche
Yin, H., Price, F., & Rudnicki, M. A. (2013) · Physiological Reviews · doi:10.1152/physrev.00043.2011 · Cited by 2,166 · see citing works
Heparan sulphate proteoglycans fine-tune mammalian physiology
Bishop, J. R., Schuksz, M., & Esko, J. D. (2007) · Nature · doi:10.1038/nature05817 · Cited by 1,631 · see citing works
Heparan Sulfate ProteoglycansPreprint
Sarrazin, S., Lamanna, W. C., & Esko, J. D. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004952 · Cited by 1,524 · see citing works
Järvinen, T. A. H., Järvinen, T. L. N., Kääriäinen, M., Kalimo, H., & Järvinen, M. (2005) · The American Journal of Sports Medicine · doi:10.1177/0363546505274714 · Cited by 1,069 · see citing works
Satellite Cells and Skeletal Muscle Regeneration
Dumont, N. A., Bentzinger, C. F., Sincennes, M., & Rudnicki, M. A. (2015) · Comprehensive Physiology · doi:10.1002/cphy.c140068 · Cited by 719 · see citing works
Rejuvenation of the muscle stem cell population restores strength to injured aged muscles
Cosgrove, B. D., Gilbert, P. M., Porpiglia, E., Mourkioti, F., Lee, S. P., Corbel, S. Y., Llewellyn, M. E., Delp, S. L., & Blau, H. M. (2014) · Nature Medicine · doi:10.1038/nm.3464 · Cited by 677 · see citing works
Bernet, J. D., Doles, J. D., Hall, J. K., Kelly Tanaka, K., Carter, T. A., & Olwin, B. B. (2014) · Nature Medicine · doi:10.1038/nm.3465 · Cited by 573 · see citing works
Self-citationOlguín, H. C., & Olwin, B. B. (2004) · Developmental Biology · doi:10.1016/j.ydbio.2004.08.015 · Cited by 573 · see citing works
Self-citationGrand, F. L., Jones, A., Seale, V., Scimè, A., & Rudnicki, M. A. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.03.013 · Cited by 531 · see citing works
Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice
Sacco, A., Mourkioti, F., Tran, R., Choi, J., Llewellyn, M., Kraft, P., Shkreli, M., Delp, S., Pomerantz, J. H., Artandi, S. E., et al. (2010) · Cell · doi:10.1016/j.cell.2010.11.039 · Cited by 512 · see citing works
Collagen VI regulates satellite cell self-renewal and muscle regeneration
Urciuolo, A., Quarta, M., Morbidoni, V., Gattazzo, F., Molon, S., Grumati, P., Montemurro, F., Tedesco, F. S., Blaauw, B., Cossu, G., et al. (2013) · Nature Communications · doi:10.1038/ncomms2964 · Cited by 511 · see citing works
Niche Regulation of Muscle Satellite Cell Self-Renewal and Differentiation
Kuang, S., Gillespie, M. A., & Rudnicki, M. A. (2008) · Cell Stem Cell · doi:10.1016/j.stem.2007.12.012 · Cited by 507 · see citing works
Muscle stem cells in development, regeneration, and diseasePreprint
Shi, X., & Garry, D. J. (2006) · Genes & Development · doi:10.1101/gad.1419406 · Cited by 502 · see citing works
Dhawan, J., & Rando, T. A. (2005) · Trends in Cell Biology · doi:10.1016/j.tcb.2005.10.007 · Cited by 466 · see citing works
Tkachenko, E., Rhodes, J., & Simons, M. (2005) · Circulation Research · doi:10.1161/01.res.0000159708.71142.c8 · Cited by 457 · see citing works
Transmembrane Signaling Proteoglycans
Couchman, J. (2010) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev-cellbio-100109-104126 · Cited by 403 · see citing works
Fibronectin Regulates Wnt7a Signaling and Satellite Cell Expansion
Bentzinger, C. F., Wang, Y. X., von Maltzahn, J., Soleimani, V. D., Yin, H., & Rudnicki, M. A. (2013) · Cell Stem Cell · doi:10.1016/j.stem.2012.09.015 · Cited by 386 · see citing works
De Micheli, A. J., Laurilliard, E. J., Heinke, C. L., Ravichandran, H., Fraczek, P., Soueid-Baumgarten, S., De Vlaminck, I., Elemento, O., & Cosgrove, B. D. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.02.067 · Cited by 373 · see citing works
The emerging biology of satellite cells and their therapeutic potential
Kuang, S., & Rudnicki, M. A. (2008) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2007.12.004 · Cited by 339 · see citing works
Skeletal muscle stem cells in developmental versus regenerative myogenesis
Tajbakhsh, S. (2009) · Journal of Internal Medicine · doi:10.1111/j.1365-2796.2009.02158.x · Cited by 333 · see citing works
Stem Cell Trafficking in Tissue Development, Growth, and Disease
Laird, D. J., von Andrian, U. H., & Wagers, A. J. (2008) · Cell · doi:10.1016/j.cell.2008.01.041 · Cited by 331 · see citing works
Pallafacchina, G., François, S., Regnault, B., Czarny, B., Dive, V., Cumano, A., Montarras, D., & BUCKINGHAM, M. E. (2009) · Stem Cell Research · doi:10.1016/j.scr.2009.10.003 · Cited by 278 · see citing works
Wen, Y., Bi, P., Liu, W., Asakura, A., Keller, C., & Kuang, S. (2012) · Molecular and Cellular Biology · doi:10.1128/mcb.06753-11 · Cited by 271 · see citing works
The p38α/β MAPK functions as a molecular switch to activate the quiescent satellite cell
Jones, N. C., Tyner, K. J., Nibarger, L., Stanley, H. M., Cornelison, D., Fedorov, Y. V., & Olwin, B. B. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200408066 · Cited by 272 · see citing works
Self-citationKelly, K. K., Hall, J. K., Troy, A. A., Cornelison, D., Majka, S. M., & Olwin, B. B. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.01.016 · Cited by 249 · see citing works
Self-citationA role for the myogenic determination gene Myf5 in adult regenerative myogenesis
Gayraud-Morel, B., Chrétien, F. C., Flamant, P., Gomès, D., Zammit, P. S., & Tajbakhsh, S. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.08.059 · Cited by 240 · see citing works
Ohkawara, B., Glinka, A., & Niehrs, C. (2011) · Developmental Cell · doi:10.1016/j.devcel.2011.01.006 · Cited by 226 · see citing works
Regulation of skeletal muscle stem cells by fibroblast growth factors
Pawlikowski, B. T., Vogler, T. O., Gadek, K. E., & Olwin, B. B. (2017) · Developmental Dynamics · doi:10.1002/dvdy.24495 · Cited by 204 · see citing works
Self-citationLying low but ready for action: the quiescent muscle satellite cell
Montarras, D., L’honoré, A., & BUCKINGHAM, M. E. (2013) · FEBS Journal · doi:10.1111/febs.12372 · Cited by 199 · see citing works
Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD
Kanisicak, O., Mendez, J. J., Yamamoto, S., Yamamoto, M., & Goldhamer, D. J. (2009) · Developmental Biology · doi:10.1016/j.ydbio.2009.05.554 · Cited by 192 · see citing works
Stem cell activation in skeletal muscle regeneration
Fu, X., Wang, H.-T., & Hu, P. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1819-5 · Cited by 161 · see citing works
3D Timelapse Analysis of Muscle Satellite Cell Motility
Siegel, A. L., Atchison, K., Fisher, K. E., Davis, G. E., & Cornelison, D. (2009) · Stem Cells · doi:10.1002/stem.178 · Cited by 184 · see citing works
Self-citationSyndecan 4 is required for endothelial alignment in flow and atheroprotective signaling
Baeyens, N., Mulligan‐Kehoe, M. J., Corti, F., Simon, D., Ross, T. D., Rhodes, J., Wang, T. Z., Mejean, C. O., Simons, M., Humphrey, J. D., et al. (2014) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1413725111 · Cited by 172 · see citing works
The extracellular matrix dimension of skeletal muscle development
Thorsteinsdóttir, S., Deries, M., Cachaço, A. S., & Bajanca, F. (2011) · Developmental Biology · doi:10.1016/j.ydbio.2011.03.015 · Cited by 167 · see citing works
Lee, S., Huynh, T. V., Lee, Y., Sebald, S. M., Wilcox‐Adelman, S. A., Iwamori, N., Lepper, C., Matzuk, M. M., & Fan, C. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1206410109 · Cited by 167 · see citing works
Self-citationAcuña, M. J., Pessina, P., Olguín, H. C., Cabrera, D., Vio, C. P., Bäder, M., Muñoz‐Cánoves, P., Santos, R. A. S., Cabello‐Verrugio, C., & Brandan, E. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt514 · Cited by 159 · see citing works
Increased Stiffness in Aged Skeletal Muscle Impairs Muscle Progenitor Cell Proliferative Activity
Lacraz, G., Rouleau, A.-J., Couture, V., Söllrald, T., Drouin, G., Veillette, N., Grandbois, M., & Grenier, G. (2015) · PLoS ONE · doi:10.1371/journal.pone.0136217 · Cited by 156 · see citing works
Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions
Olguín, H. C., & Pisconti, A. (2011) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2011.01348.x · Cited by 147 · see citing works
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy
Morales, M. G., Gutiérrez, J., Cabello‐Verrugio, C., Cabrera, D., Lipson, K. E., Goldschmeding, R., & Brandan, E. (2013) · Human Molecular Genetics · doi:10.1093/hmg/ddt352 · Cited by 146 · see citing works
Molecular regulation of satellite cell function
Holterman, C. E., & Rudnicki, M. A. (2005) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2005.07.004 · Cited by 141 · see citing works
Skeletal muscle stem cell birth and properties
Sambasivan, R., & Tajbakhsh, S. (2007) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2007.09.013 · Cited by 143 · see citing works
Satellite Cells and Skeletal Muscle Regeneration
Dumont, N. A., Bentzinger, C., Sincennes, M.-C., & Rudnicki, M. (2015) · Comprehensive Physiology · doi:10.1002/j.2040-4603.2015.tb00646.x · Cited by 682 · see citing works
Cosgrove, B. D., Sacco, A., Gilbert, P. M., & Blau, H. M. (2009) · Differentiation · doi:10.1016/j.diff.2009.08.004 · Cited by 135 · see citing works
Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay
Hausburg, M. A., Doles, J. D., Clement, S. L., Cadwallader, A. B., Hall, M. N., Blackshear, P. J., Lykke‐Andersen, J., & Olwin, B. B. (2015) · eLife · doi:10.7554/elife.03390 · Cited by 136 · see citing works
Self-citationCarnes, M. E., & Pins, G. D. (2020) · Bioengineering · doi:10.3390/bioengineering7030085 · Cited by 141 · see citing works
ERK2 is required for efficient terminal differentiation of skeletal myoblasts
Li, J., & Johnson, S. E. (2006) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2006.05.051 · Cited by 137 · see citing works
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS
Lathia, J. D., Patton, B. L., Eckley, D. M., Magnus, T., Mughal, M. R., Sasaki, T., Caldwell, M. A., Rao, M. S., Mattson, M. P., & ffrench‐Constant, C. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21520 · Cited by 135 · see citing works
The Muscle Stem Cell Niche in Health and Disease
Mashinchian, O., Pisconti, A., Moal, E. L., & Bentzinger, C. F. (2017) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2017.08.003 · Cited by 127 · see citing works
Syndecan-3 and Notch cooperate in regulating adult myogenesis
Pisconti, A., Cornelison, D., Olguín, H. C., Antwine, T. L., & Olwin, B. B. (2010) · The Journal of Cell Biology · doi:10.1083/jcb.201003081 · Cited by 126 · see citing works
Self-citationPrmt5 is a regulator of muscle stem cell expansion in adult mice
Zhang, T., Günther, S., Looso, M., Kuenne, C. T., Krüger, M., Kim, J., Zhou, Y., & Braun, T. W. (2015) · Nature Communications · doi:10.1038/ncomms8140 · Cited by 131 · see citing works
Gutiérrez, J., & Brandan, E. (2010) · Molecular and Cellular Biology · doi:10.1128/mcb.01164-09 · Cited by 122 · see citing works
Ellefsen, S., Hammarström, D., Strand, T. A., Zacharoff, E., Whist, J. E., Rauk, I., Nygaard, H., Vegge, G., Hanestadhaugen, M., Wernbom, M., et al. (2015) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00497.2014 · Cited by 122 · see citing works
Wang, C., Rabadan Ros, R., Martinez-Redondo, P., Ma, Z., Shi, L., Xue, Y., Guillen-Guillen, I., Huang, L., Hishida, T., Liao, H.-K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-23353-z · Cited by 119 · see citing works
Millette, E., Rauch, B. H., Kenagy, R. D., Daum, G., & Clowes, A. W. (2005) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2005.11.003 · Cited by 119 · see citing works
Prevention of Muscle Aging by Myofiber-Associated Satellite Cell Transplantation
Hall, J. K., Banks, G., Chamberlain, J., & Olwin, B. (2010) · Science Translational Medicine · doi:10.1126/scitranslmed.3001081 · Cited by 124 · see citing works
Self-citationThe Muscle Stem Cell Niche: Regulation of Satellite Cells During Regeneration
Boonen, K. J. M., & Post, M. J. (2008) · Tissue Engineering Part B Reviews · doi:10.1089/ten.teb.2008.0045 · Cited by 114 · see citing works
Six1 regulates stem cell repair potential and self-renewal during skeletal muscle regeneration
Grand, F. L., Grifone, R., Mourikis, P., Houbron, C., Gigaud, C., Pujol, J., Maillet, M., Pagès, G., Rudnicki, M. A., Tajbakhsh, S., et al. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201201050 · Cited by 113 · see citing works
Dews, I. C., & MacKenzie, K. R. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0708909105 · Cited by 113 · see citing works
Slow-dividing satellite cells retain long-term self-renewal ability in adult muscle
Ono, Y., Masuda, S., Nam, H.-S., Benezra, R., Miyagoe‐Suzuki, Y., & Takeda, S. (2012) · Journal of Cell Science · doi:10.1242/jcs.096198 · Cited by 109 · see citing works
Neural cell adhesion molecule (NCAM) marks adult myogenic cells committed to differentiation
Capkovic, K. L., Stevenson, S. E., Johnson, M. C., Thelen, J. J., & Cornelison, D. (2008) · Experimental Cell Research · doi:10.1016/j.yexcr.2008.01.021 · Cited by 109 · see citing works
Self-citationMultifunctionality of extracellular and cell surface heparan sulfate proteoglycans
Kirn‐Safran, C. B., Farach‐Carson, M. C., & Carson, D. D. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0096-1 · Cited by 103 · see citing works
Anderson, J. E. (2006) · Journal of Experimental Biology · doi:10.1242/jeb.02088 · Cited by 103 · see citing works
Cell–matrix interactions in muscle disease
Carmignac, V., & Durbeej, M. (2011) · The Journal of Pathology · doi:10.1002/path.3020 · Cited by 100 · see citing works
Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells
Gayraud-Morel, B., Chrétien, F. C., Jory, A., Sambasivan, R., Négroni, E., Flamant, P., Soubigou, G., Coppée, J., Santo, J. P. D., Cumano, A., et al. (2012) · Journal of Cell Science · doi:10.1242/jcs.097006 · Cited by 92 · see citing works
Skeletal Muscle as a Paradigm for Regenerative Biology and Medicine
Gayraud-Morel, B., Chrétien, F. C., & Tajbakhsh, S. (2009) · Regenerative Medicine · doi:10.2217/17460751.4.2.293 · Cited by 93 · see citing works
Morton, A. B., Norton, C. E., Jacobsen, N. L., Fernando, C. A., Cornelison, D., & Segal, S. S. (2019) · Skeletal Muscle · doi:10.1186/s13395-019-0213-2 · Cited by 90 · see citing works
Self-citationSox15 and Fhl3 transcriptionally coactivate Foxk1 and regulate myogenic progenitor cells
Meeson, A. P., Shi, X., Alexander, M. S., Williams, R. S., Allen, R. E., Jiang, N., Adham, I. M., Goetsch, S. C., Hammer, R. E., & Garry, D. J. (2007) · The EMBO Journal · doi:10.1038/sj.emboj.7601635 · Cited by 88 · see citing works
Comparative myogenesis in teleosts and mammals
Rossi, G., & Messina, G. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1604-5 · Cited by 81 · see citing works
Collins, C. A. (2006) · Current Opinion in Pharmacology · doi:10.1016/j.coph.2006.01.006 · Cited by 87 · see citing works
Kalus, I., Salmen, B., Viebahn, C., FIGURA, K. V., Schmitz, D., D’Hooge, R., & Dierks, T. (2008) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2008.00558.x · Cited by 82 · see citing works
Myostatin: a skeletal muscle chalone
Lee, S.-J. (2023) · Annual Review of Physiology · doi:10.1146/annurev-physiol-012422-112116 · Cited by 84 · see citing works
Extracellular matrix: Brick and mortar in the skeletal muscle stem cell niche
Schüler, S. C., Liu, Y., Dumontier, S., Grandbois, M., Moal, E. L., Cornelison, D., & Bentzinger, C. F. (2022) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2022.1056523 · Cited by 82 · see citing works
Self-citationMASTR directs MyoD-dependent satellite cell differentiation during skeletal muscle regenerationPreprint
Mokalled, M. H., Johnson, A. N., Creemers, E. E., & Olson, E. N. (2012) · Genes & Development · doi:10.1101/gad.179663.111 · Cited by 81 · see citing works
Heparan Sulfate Chain Valency Controls Syndecan-4 Function in Cell Adhesion
Gopal, S., Bober, A., Whiteford, J. R., Multhaupt, H. A. B., Yoneda, A., & Couchman, J. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m109.056945 · Cited by 80 · see citing works
Langsdorf, A. E., Do, A.-T., Kusche‐Gullberg, M., Emerson, C. P., & Ai, X. (2007) · Developmental Biology · doi:10.1016/j.ydbio.2007.08.053 · Cited by 80 · see citing works
Role of skeletal muscle proteoglycans during myogenesis
Brandan, E., & Gutiérrez, J. (2013) · Matrix Biology · doi:10.1016/j.matbio.2013.03.007 · Cited by 79 · see citing works
Syndecan-4 Clustering Induces Cell Migration in a PDZ-Dependent Manner
Tkachenko, E., Elfenbein, A., Tı̂rziu, D., & Simons, M. (2006) · Circulation Research · doi:10.1161/01.res.0000225283.71490.5a · Cited by 79 · see citing works
Heparan sulfate proteoglycans: A GAGgle of skeletal‐hematopoietic regulators
Bungartz, K. D., Antonio, J. D. S., & Jacenko, O. (2008) · Developmental Dynamics · doi:10.1002/dvdy.21593 · Cited by 78 · see citing works
Stra13 regulates satellite cell activation by antagonizing Notch signaling
Sun, H., Li, L., Vercherat, C., Gülbağcı, N. T., Acharjee, S., Li, J., Chung, T., Thin, T. H., & Taneja, R. (2007) · The Journal of Cell Biology · doi:10.1083/jcb.200609007 · Cited by 76 · see citing works
Notch and Wnt Signaling, Physiological Stimuli and Postnatal Myogenesis
Tsivitse, S. K. (2010) · International Journal of Biological Sciences · doi:10.7150/ijbs.6.268 · Cited by 72 · see citing works
Eph/ephrin interactions modulate muscle satellite cell motility and patterning
Stark, D. A., Karvas, R. M., Siegel, A. L., & Cornelison, D. (2011) · Development · doi:10.1242/dev.068411 · Cited by 72 · see citing works
Self-citationComplexity of Extracellular Matrix and Skeletal Muscle Regeneration
Grounds, M. D. (2008) · Springer eBooks · doi:10.1007/978-1-4020-6768-6_13 · Cited by 71 · see citing works
Sun, L., Yang, H., Chen, M., Ma, D., & Lin, C. (2013) · PLoS ONE · doi:10.1371/journal.pone.0069441 · Cited by 71 · see citing works
Mahalingam, Y., Gallagher, J. T., & Couchman, J. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m604938200 · Cited by 71 · see citing works
Molecular and cell-based therapies for muscle degenerations: a road under construction
Berardi, E., Annibali, D., Cassano, M., Crippa, S., & Sampaolesi, M. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00119 · Cited by 69 · see citing works
Minireview: Syndecans and their crucial roles during tissue regeneration
Chung, H., Multhaupt, H. A. B., Oh, E., & Couchman, J. (2016) · FEBS Letters · doi:10.1002/1873-3468.12280 · Cited by 68 · see citing works
Tsika, R. W., Schramm, C., Simmer, G., Fitzsimons, D. P., Moss, R. L., & Ji, J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m807461200 · Cited by 65 · see citing works
Cho, D. S., & Doles, J. D. (2017) · Gene · doi:10.1016/j.gene.2017.09.014 · Cited by 64 · see citing works
Syndecan-1 deficiency aggravates anti-glomerular basement membrane nephritis
Rops, A. L. W. M. M., Götte, M., Baselmans, M., van den Hoven, M. J., Steenbergen, E. J., Lensen, J. F. M., Wijnhoven, T. J. M., Cevikbas, F., van den Heuvel, L. P., Kuppevelt, T. H. V., et al. (2007) · Kidney International · doi:10.1038/sj.ki.5002514 · Cited by 64 · see citing works
Kucherenko, M. M., Pantoja, M., Yatsenko, A. S., Shcherbata, H. R., Fischer, K. A., Maksymiv, D. V., Chernyk, Y. I., & Ruohola‐Baker, H. (2008) · PLoS ONE · doi:10.1371/journal.pone.0002418 · Cited by 63 · see citing works
Stem Cells for Skeletal Muscle Regeneration: Therapeutic Potential and Roadblocks
Rinaldi, F., & Perlingeiro, R. (2013) · Translational Research: The Journal of Laboratory and Clinical Medicine · doi:10.1016/j.trsl.2013.11.006 · Cited by 59 · see citing works
Velleman, S. G., Nestor, K., Coy, C. S., Harford, I., & ANTHONY, N. B. (2010) · International Journal of Poultry Science · doi:10.3923/ijps.2010.417.425 · Cited by 63 · see citing works
Incidence and severity of myofiber branching with regeneration and aging
Pichavant, C., & Pavlath, G. K. (2014) · Skeletal Muscle · doi:10.1186/2044-5040-4-9 · Cited by 61 · see citing works
Lopes, N., Galluso, J., Escalière, B., Carpentier, S., Kerdiles, Y. M., & Vivier, É. (2022) · Cell Reports Medicine · doi:10.1016/j.xcrm.2022.100812 · Cited by 62 · see citing works
Isaac, C. E., Wright, A., Ūsas, A., Li, H., Tang, Y., Mu, X., Greco, N., Dong, Q. D., Vo, N. N., Kang, J. D., et al. (2012) · Journal of Orthopaedic Research® · doi:10.1002/jor.22236 · Cited by 61 · see citing works
In vitro indeterminate teleost myogenesis appears to be dependent on Pax3
Froehlich, J. M., Galt, N. J., Charging, M. J., Meyer, B. M., & Biga, P. R. (2013) · In Vitro Cellular & Developmental Biology - Animal · doi:10.1007/s11626-013-9616-2 · Cited by 60 · see citing works
Syndecan-4 in Tumor Cell Motility
Keller-Pintér, A., Gyulai-Nagy, S., Becsky, D., László, A., & Rovó, L. (2021) · Cancers · doi:10.3390/cancers13133322 · Cited by 59 · see citing works
Ghadiali, R. S., Guimond, S. E., Turnbull, J. E., & Pisconti, A. (2016) · Matrix Biology · doi:10.1016/j.matbio.2016.07.007 · Cited by 52 · see citing works
A Conserved Role for Syndecan Family Members in the Regulation of Whole-Body Energy Metabolism
Luca, M. D., Klimentidis, Y., Casazza, K., Chambers, M. M., Cho, R., Harbison, S. T., Jumbo-Lucioni, P., Zhang, S.-Y., Leips, J., & Fernández, J. R. (2010) · PLoS ONE · doi:10.1371/journal.pone.0011286 · Cited by 45 · see citing works
Serum syndecan-4 is a novel biomarker for patients with chronic heart failure
Takahashi, R., Negishi, K., Watanabe, A., Arai, M., Naganuma, F., Ohyama, Y., & Kurabayashi, M. (2011) · Journal of Cardiology · doi:10.1016/j.jjcc.2011.01.012 · Cited by 52 · see citing works
- Authors
- Cornelison, D. D. W., Wilcox-Adelman, S. A., Goetinck, P. F., Rauvala, H., Rapraeger, A. C., & Olwin, B. B.
- Affiliations
- University of Helsinki (FI)
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2004-09-15
- Volume
- 18
- Issue
- 18
- Pages
- 2231-2236
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- PMC
- PMC517515
- OpenAlex
- W2094191351
- Cited by
- 317
- References
- 20
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 14 · 2023: 12 · 2022: 14 · 2021: 11 · 2020: 21 · 2019: 12 · 2018: 7 · 2017: 12 · 2016: 14 · 2015: 17 · 2014: 18 · 2013: 26 · 2012: 21
- Type
- posted content
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Genes & Development (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- American Heart Association
- National Institutes of Health (AR39467)
- National Institute of General Medical Sciences (GM 48850, R01GM048850)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR39467, R01AR039467)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD37490, HD21881, R01HD037490)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Proteoglycans and glycosaminoglycans research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Keywords
- syndecan-3, syndecan-4, skeletal muscle development, muscle regeneration, satellite cells, muscular dystrophy, MyoD, myotube fusion, satellite cell differentiation, tyrosine phosphorylation, muscle fibrosis
- MeSH terms
- Animals, Cell Division, Cells, Cultured, Female, Membrane Glycoproteins, Mice, Mutant Strains, Muscular Dystrophies, Proteoglycans, Regeneration, MyoD Protein, Muscle, Skeletal, Muscle Fibers, Skeletal, Gene Expression Regulation, Developmental, Muscle Development, Satellite Cells, Skeletal Muscle, Mice, Syndecan-3, Syndecan-4
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