p53 isoforms can regulate p53 transcriptional activity

Antibodies, a laboratory manual

(1989) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(89)90130-3 · Cited by 12,318

T antigen is bound to a host protein in SY40-transformed cells

Lane, D. P., & Crawford, L. V. (1979) · Nature · doi:10.1038/278261a0 · Cited by 2,456

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

Linzer, D. I. H., & Levine, A. J. (1979) · Cell · doi:10.1016/0092-8674(79)90293-9 · Cited by 1,814

p53 mutant mice that display early ageing-associated phenotypes

Tyner, S. D., Venkatachalam, S., Choi, J., Jones, S., Ghebranious, N., Igelmann, H., Lu, X., Soron, G., Cooper, B., Brayton, C., et al. (2002) · Nature · doi:10.1038/415045a · Cited by 1,459

Decision making by p53: life, death and cancer

Oren, M. (2003) · Cell Death and Differentiation · doi:10.1038/sj.cdd.4401183 · Cited by 1,085

Detection of a transformation-related antigen in chemically induced sarcomas and other transformed cells of the mouse.

DeLeo, A. B., Jay, G. D., Appella, E., DuBois, G. C., Law, L. W., & Old, L. J. (1979) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.76.5.2420 · Cited by 721

Modulation of mammalian life span by the short isoform of p53

Maier, B., Gluba, W., Bernier, B., Turner, T., Mohammad, K., Guise, T., Sutherland, A., Thorner, M., & Scrable, H. (2004) · Genes & Development · doi:10.1101/gad.1162404 · Cited by 586

Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

Xirodimas, D. P., Saville, M. K., Bourdon, J.-C., Hay, R. T., & Lane, D. P. (2004) · Cell · doi:10.1016/j.cell.2004.06.016 · Cited by 570

On the shoulders of giants: p63, p73 and the rise of p53

Yang, A., Kaghad, M., Caput, D., & McKeon, F. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(02)02595-7 · Cited by 496

Drosophila p53 Binds a Damage Response Element at the reaper Locus

Brodsky, M. H., Nordstrom, W., Tsang, G., Kwan, E., Rubin, G. M., & Abrams, J. (2000) · Cell · doi:10.1016/s0092-8674(00)80627-3 · Cited by 474

Status of p53 in first-trimester cytotrophoblastic cells

Cohen, M., Meisser, A., Haenggeli, L., Irminger‐Finger, I., & Bischof, P. (2006) · Molecular Human Reproduction · doi:10.1093/molehr/gal105 · Cited by 14

p53 Pathway Alterations in Brain Tumors

Yin, S., & Meir, E. G. V. (2009) · Humana Press eBooks · doi:10.1007/978-1-60327-553-8_14 · Cited by 15

Biochemical and Functional Evidence of p53 Homology Is Inconsistent with Molecular Phylogenetics for Distant Sequences

Fernandes, A. D., & Atchley, W. R. (2008) · Journal of Molecular Evolution · doi:10.1007/s00239-008-9124-2 · Cited by 14

Dissecting Genomic Aberrations in Myeloproliferative Neoplasms by Multiplex-PCR and Next Generation Sequencing

Kirschner, M., Schemionek, M., Schubert, C., Chatain, N., Sontag, S., Isfort, S., Ortiz‐Brüchle, N., Schmitt, K., Krüger, L., Zerres, K., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0123476 · Cited by 14

Increased Expression of the Δ133p53β Isoform Enhances Brain Metastasis

Jesus, A. N. B. D., Taha, A. J., Wang, D., Mehta, P. M., Mehta, S. Y., Reily-Bell, A. L., Lekamlage, S. P., Saraiva, A. M., Tahmeedzaman, T., Ziad, F., et al. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24021267 · Cited by 13

Role of p53 isoforms in the DNA damage response during Drosophila oogenesis

Park, J., Nguyen, T. T. N., Lee, E.-M., Castro-Aceituno, V., Wagle, R., Lee, K.-S., Choi, J., & Song, Y. (2019) · Scientific Reports · doi:10.1038/s41598-019-47913-y · Cited by 13

RNA-Seq reveals the existence of a CDKN1C-E2F1-TP53 axis that is altered in human T-cell lymphoblastic lymphomas

López‐Nieva, P., Fernández‐Navarro, P., Vaquero‐Lorenzo, C., Villa‐Morales, M., Graña‐Castro, O., Cobos-Fernández, M., Lorenzo, J. L. L., Llamas, P., González-Sánchez, L., Sastre, I., et al. (2018) · BMC Cancer · doi:10.1186/s12885-018-4304-y · Cited by 13

Helpers of the cellular gatekeeper—miRNAs dance in P53 network

Shi, M., Liu, D., Shen, B., & Guo, N. (2009) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2009.12.001 · Cited by 13

Cellular responses to DNA damage: Current state of the field and review of the 52nd Benzon Symposium

Lukas, J., Bohr, V. A., & Halazonetis, T. D. (2006) · DNA repair · doi:10.1016/j.dnarep.2006.01.006 · Cited by 13

(Intrinsically disordered) splice variants in the proteome: implications for novel drug discovery

Uversky, V. N. (2016) · Genes & Genomics · doi:10.1007/s13258-015-0384-0 · Cited by 13

p53 isoform expression promotes a stemness phenotype and inhibits doxorubicin sensitivity in breast cancer

Reinhardt, L. S., Groen, K., Zhang, X., Morten, B. C., Wawruszak, A., & Avery‐Kiejda, K. A. (2023) · Cell Death and Disease · doi:10.1038/s41419-023-06031-4 · Cited by 12

Re-appraising the evidence for the source, regulation and function of p53-family isoforms

López, I., Valdivia, I. L., Vojtěšek, B., Fåhræus, R., & Coates, P. J. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae855 · Cited by 13

Circular RNA role in Atherosclerosis Development and Progression

Greco, S., Gaetano, C., Mazzaccaro, D., & Martelli, F. (2025) · Current Atherosclerosis Reports · doi:10.1007/s11883-025-01306-x · Cited by 18

Characterization of the human PAP1 gene and its homologue possible involvement in mouse embryonic development

Shu, K., Wu, L., Xie, Y., Zhao, J., Liang, Y., & Li, B. (2006) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2006.05.021 · Cited by 12

MDM2 Implications for Potential Molecular Pathogenic Therapies of Soft-Tissue Tumors

Sun, S. Y. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12113638 · Cited by 12

Prevalence of Allelic Loss at TP53 in Endometrial Carcinomas

Semczuk, A., Schneider‐Stock, R., & Szewczuk, W. (2010) · Oncology · doi:10.1159/000314353 · Cited by 12

p53 protein expression in chronic lymphocytic leukemia

Sellmann, L., Carpinteiro, A., Nückel, H., Scholtysik, R., Siemer, D., Klein-Hipass, L., Kube, D., Dürig, J., Dührsen, U., Stanelle, J., et al. (2012) · Leukemia & lymphoma/Leukemia and lymphoma · doi:10.3109/10428194.2011.654115 · Cited by 12

The Δ133p53 Isoform Reduces Wtp53-induced Stimulation of DNA Pol γ Activity in the Presence and Absence of D4T

Liu, K., Zang, Y., Guo, X., Wei, F., Yin, J., Pang, L., & Chen, D. (2017) · Aging and Disease · doi:10.14336/ad.2016.0910 · Cited by 12

MOLECULAR BIOLOGY OF COLORECTAL CANCER

(2008) · Elsevier eBooks · doi:10.1016/b978-0-7020-2723-9.50029-4 · Cited by 12

In vivo evaluation of the role of DNp73α protein in regulating the p53‐dependent apoptotic pathway after treatment with cytotoxic drugs

Sabatino, M. A., Previdi, S., & Broggini, M. (2006) · International Journal of Cancer · doi:10.1002/ijc.22362 · Cited by 12

A p53 Axis Regulates B Cell Receptor-Triggered, Innate Immune System-Driven B Cell Clonal Expansion

Lee, H., Haque, S., Nieto, J., Trott, J., Inman, J. K., McCormick, S. A., Chiorazzi, N., & Mongini, P. K. A. (2012) · The Journal of Immunology · doi:10.4049/jimmunol.1103037 · Cited by 13

Interaction of p53 with the Δ133p53α and Δ160p53α isoforms regulates p53 conformation and transcriptional activity

Tomas, F., Roux, P., & Gire, V. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-07213-4 · Cited by 11

Pushing the annotation of cellular activities to a higher resolution: Predicting functions at the isoform level

Li, W., Liu, C.-C., Kang, S., Li, J., Tseng, Y., & Zhou, X. J. (2015) · Methods · doi:10.1016/j.ymeth.2015.07.016 · Cited by 11

Detection and Functional Analysis of TP53 Mutations in CLL

Pavlová, Š., Šmardová, J., Tom, N., & Trbušek, M. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-8876-1_6 · Cited by 11

New insights into the interactions of HPV-16 E6*I and E6*II with p53 isoforms and induction of apoptosis in cancer-derived cell lines

Antonio-Véjar, V., Ortíz-Sánchez, E., Chalma, P. R., Patiño-Morales, C. C., Guido‐Jiménez, M., Alvarado-Ortiz, E., Hernández, G., & García-Carrancá, A. M. (2022) · Pathology - Research and Practice · doi:10.1016/j.prp.2022.153890 · Cited by 11

The Important Role of Protein Kinases in the p53 Sestrin Signaling Pathway

Gülow, K., Tümen, D., & Kunst, C. (2023) · Cancers · doi:10.3390/cancers15225390 · Cited by 13

Protective effect of copper II ‐albumin complex against aflatoxin B1 ‐ induced hepatocellular toxicity: The impact of Nrf2, PPAR ‐γ, and NF‐kB in these protective effects

Abo‐Hiemad, H. M., Nassar, A. Y., Shatat, A. R., Mohamed, M. A., Soliman, M., Abdelrady, Y. A., & Sayed, A. M. M. (2022) · Journal of Food Biochemistry · doi:10.1111/jfbc.14160 · Cited by 11

Analysis of p53–RNA interactions in cultured human cells

Riley, K. J.-L., & Maher, L. J. (2007) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2007.08.181 · Cited by 13

Accumulation of inactive p53 protein in oral squamous cell carcinoma: stabilization by protein interaction

Francis, G., Kumar, U. D., Nalinakumari, K. R., Jayasree, K., & Kannan, S. (2012) · European Journal Of Oral Sciences · doi:10.1111/eos.12007 · Cited by 11

Cells Expressing Murine RAD52 Splice Variants Favor Sister Chromatid Repair

Thorpe, P. H., Marrero, V. A., Savitzky, M. H., Šunjevarić, I., Freeman, T. C., & Rothstein, R. J. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.26.10.3752-3763.2006 · Cited by 11

Distinct functions of wild-type and R273H mutant Δ133p53α differentially regulate glioblastoma aggressiveness and therapy-induced senescence

Joruiz, S. M., von Muhlinen, N., Horikawa, I., Gilbert, M. R., & Harris, C. C. (2024) · Cell Death and Disease · doi:10.1038/s41419-024-06769-5 · Cited by 13

An Alternatively Spliced Gain-of-Function NT5C2 Isoform Contributes to Chemoresistance in Acute Lymphoblastic Leukemia

Torres-Diz, M., Reglero, C., Falkenstein, C. D., Castro, A., Hayer, K. E., Radens, C. M., Quesnel-Vallières, M., Ang, Z., Sehgal, P. D., Li, M. M., et al. (2024) · Cancer Research · doi:10.1158/0008-5472.can-23-3804 · Cited by 10

Identification and characterization of the binding sequences and target genes of p53 lacking the 1st transactivation domain

Suzuki, S., Tsutsumi, S., Chen, Y., Ozeki, C., Okabe, A., Kawase, T., Aburatani, H., & Ohki, R. (2019) · Cancer Science · doi:10.1111/cas.14279 · Cited by 10

CCR4‑NOT transcription complex subunit�2�regulates TRAIL sensitivity in non‑small‑cell lung cancer cells via the STAT3 pathway

Kim, E. O., Kang, S., Choi, M., Rhee, K., & Yun, M. (2019) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2019.4425 · Cited by 10

Identification of a novel, transactivation-defective splicing variant of p53 gene in patients with chronic lymphocytic leukemia

Peková, Š., Čmejla, R., Smolej, L., Kozák, T., Špaček, M., & Průcha, M. (2007) · Leukemia Research · doi:10.1016/j.leukres.2007.06.022 · Cited by 10

Cooperation of p53 Mutations with Other Oncogenic Alterations in Cancer

Girardini, J. E., Walerych, D., & Sal, G. D. (2014) · Sub-cellular biochemistry/Subcellular biochemistry · doi:10.1007/978-94-017-9211-0_3 · Cited by 10

ΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion

Yang, K., Wu, W., Chen, Y.-C., Lo, S. H., & Liao, Y. (2016) · PLoS ONE · doi:10.1371/journal.pone.0147542 · Cited by 10

Structural-functional diversity of p53 proteoforms

Naryzhny, S., & Legina, O. K. (2019) · Biomeditsinskaya Khimiya · doi:10.18097/pbmc20196504263 · Cited by 10

Genetic Drivers of Head and Neck Squamous Cell Carcinoma: Aberrant Splicing Events, Mutational Burden, HPV Infection and Future Targets

Dlamini, Z., Alaouna, M., Mbatha, S. Z., Bhayat, A., Mabongo, M., Chatziioannou, A. A., & Hull, R. (2021) · Genes · doi:10.3390/genes12030422 · Cited by 11

Tracing the protectors path from the germ line to the genome

Coutandin, D., Ou, H. D., Löhr, F., & Dötsch, V. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1001069107 · Cited by 10

p53 Isoform Δ113p53 in Zebrafish

Chen, J., & Peng, J. (2009) · Zebrafish · doi:10.1089/zeb.2009.0598 · Cited by 10

A naturally occurring 4-bp deletion in the intron 4 of p53 creates a spectrum of novel p53 isoforms with anti-apoptosis function

Shi, H., Tao, T., Huang, D., Ou, Z., Chen, J., & Peng, J. (2014) · Nucleic Acids Research · doi:10.1093/nar/gku1359 · Cited by 10

Mutant p53 protein expression and antioxidant status deficiency in breast cancer

Milićević, Z., Kasapović, J., Gavrilović, L., Milovanović, Z., Bajić, V., & Spremo‐Potparević, B. (2014) · Europe PMC (PubMed Central) · doi:10.17877/de290r-6859 · Cited by 10

Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription

Hudson, C. D., Sayan, E., Melino, G., Knight, R. A., Latchman, D. S., & Budhram-Mahadeo, V. S. (2008) · Cell Death and Differentiation · doi:10.1038/cdd.2008.45 · Cited by 10

p73 expression modulates p63 and Mdm2 protein presence in complex with p53 family-specific DNA target sequence in squamous cell carcinogenesis

Johnson, J. L., Lagowski, J. P., Lawson, S. K., Liu, Y., & Kulesz-Martin, M. F. (2007) · Oncogene · doi:10.1038/sj.onc.1210941 · Cited by 10

Navigating the complexity of p53-DNA binding: implications for cancer therapy

Thayer, K. M., Stetson, S., Caballero, F., Chiu, C., & Han, I. S. M. (2024) · Biophysical Reviews · doi:10.1007/s12551-024-01207-4 · Cited by 9

Germline variant affecting p53β isoforms predisposes to familial cancer

Schubert, S. A., Ruano, D., Joruiz, S. M., Stroosma, J., Glavak, N., Montali, A., Pinto, L., Rodríguez‐Girondo, M., Barge‐Schaapveld, D. Q. C. M., Nielsen, M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-52551-8 · Cited by 10

Decoding the general role of tRNA queuosine modification in eukaryotes

Díaz-Rullo, J., González-Moreno, L., del Arco, A., & González‐Pastor, J. E. (2025) · Scientific Reports · doi:10.1038/s41598-024-83451-y · Cited by 9

p53—Guardian AngelandArchangel

Chakarov, S., Petkova, R., & Russev, G. C. (2012) · Biotechnology & Biotechnological Equipment · doi:10.5504/bbeq.2011.0145 · Cited by 8

Nonsense-mediated mRNA decay inhibition synergizes with MDM2 inhibition to suppress TP53 wild-type cancer cells in p53 isoform-dependent manner

Li, Y., Wu, M. Y., Zhang, L., Wan, L., Li, H., Zhang, L., Sun, G., Huang, W., Zhang, J., Su, F., et al. (2022) · Cell Death Discovery · doi:10.1038/s41420-022-01190-3 · Cited by 10

Do p53 stress responses impact organismal aging?

Hasty, P., Campisi, J., & Sharp, Z. D. (2016) · Translational Cancer Research · doi:10.21037/tcr.2016.12.02 · Cited by 9

Δ40p53 is involved in the inactivation of autophagy and contributes to inhibition of cell death in HCT116-Δ40p53 cells

Zang, Y., Shi, Y., Liu, K., Qiao, L., Guo, X., & Chen, D. (2017) · Oncotarget · doi:10.18632/oncotarget.14460 · Cited by 9

Loss of digestive organ expansion factor (Diexf) reveals an essential role during murine embryonic development that is independent of p53

Aryal, N. K., Wasylishen, A. R., Pant, V., Riley-Croce, M., & Lozano, G. (2017) · Oncotarget · doi:10.18632/oncotarget.22087 · Cited by 9

The first two confirmed sub-Saharan African families with germline TP53 mutations causing Li-Fraumeni syndrome

Macaulay, S., Goodyear, Q. C., Kruger, M., Chen, W. C., Essop, F., & Krause, A. (2018) · Familial Cancer · doi:10.1007/s10689-018-0075-5 · Cited by 9

p53 transcriptional pathways in breast cancer: the good, the bad and the complex

Thompson, A. M., & Lane, D. P. (2009) · The Journal of Pathology · doi:10.1002/path.2674 · Cited by 9

Loss of heterozygosity of the p53 gene and deregulated expression of its mRNA and protein in human brain tumors

Rohini, K., Jothi, M., Prabhu, P. D. A. H., Subbakrishna, D., Gope, M. L., Chandramouli, B. A., Sampath, S., Anandh, B., & Gope, R. (2006) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-006-9374-5 · Cited by 9

p53: It Has It All, But Will It Make It to the Clinic As a Marker in Bladder Cancer?

Real, F. X. (2007) · Journal of Clinical Oncology · doi:10.1200/jco.2007.13.1904 · Cited by 9

Combining TP53 mutation and isoform has the potential to improve clinical practice

Das, S. R., Delahunt, B., Lasham, A., Li, K., Wright, D., Print, C. G., Slatter, T. L., Braithwaite, A. W., & Mehta, S. Y. (2024) · Pathology · doi:10.1016/j.pathol.2024.02.003 · Cited by 8

p53 Dysregulation in Breast Cancer: Insights on Mutations in the TP53 Network and p53 Isoform Expression

Reinhardt, L. S., Groen, K., Xavier, A., & Avery‐Kiejda, K. A. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241210078 · Cited by 8

Biological Effects of HDAC Inhibitors Vary with Zinc Binding Group: Differential Effects on Zinc Bioavailability, ROS Production, and R175H p53 Mutant Protein Reactivation

Flores, B., Uppalapati, C. K., Pascual, A. S., Vong, A., Baatz, M., Harrison, A. M., Leyva, K. J., & Hull, E. E. (2023) · Biomolecules · doi:10.3390/biom13111588 · Cited by 8

Updates from the TP53 universe

Pentimalli, F. (2017) · Cell Death and Differentiation · doi:10.1038/cdd.2017.190 · Cited by 8

Expression of p53 isoforms in response to two levels of hypoxia and effects of p53 knock‐down in glyceraldehyde‐3‐phosphate dehydrogenase in the white shrimp Litopenaeus vannamei

Nuñez-Hernandez, D. M., Camacho‐Jiménez, L., Leyva‐Carrillo, L., Peregrino-Uriarte, A. B., Valenzuela-Soto, E. M., Gómez‐Jiménez, S., González‐Ríos, H., & Yepiz-Plascencia, G. M. (2021) · Aquaculture Research · doi:10.1111/are.15083 · Cited by 8

p53 Protein Isoform Profiles in AML: Correlation with Distinct Differentiation Stages and Response to Epigenetic Differentiation Therapy

Haaland, I., Hjelle, S. M., Reikvam, H., Sulen, A., Ryningen, A., McCormack, E., Bruserud, Ø., & Gjertsen, B. T. (2021) · Cells · doi:10.3390/cells10040833 · Cited by 9

ΔNp73, TAp73 and Δ133p53 Extracellular Vesicle Cargo as Early Diagnosis Markers in Colorectal Cancer

Rodríguez‐Cobos, J., Viñal, D., Poves, C. F., Fernández‐Aceñero, M. J., Peinado, H., Pastor‐Morate, D., Prieto, M. I., Barderas, R., Rodrı́guez-Salas, N., & Domínguez, G. (2021) · Cancers · doi:10.3390/cancers13092240 · Cited by 8

Δ133p53 coordinates ECM-driven morphogenesis and gene expression in three-dimensional mammary epithelial acini

Lee, S., Robertson, C., Diot, A., Meuray, V., Bourdon, J., & Bissell, M. J. (2022) · Journal of Cell Science · doi:10.1242/jcs.259673 · Cited by 8

Sonic hedgehog signaling: Alternative splicing and pathogenic role in medulloblastoma

Qu, M., He, Q., Luo, J., Shen, T., Gao, R., Xu, Y., Xu, C., Barkat, M. Q., Zeng, L., & Wu, X. (2022) · Genes & Diseases · doi:10.1016/j.gendis.2022.10.014 · Cited by 8

Leukocyte p53 protein biosignature through standard-aligned two-dimensional immunoblotting

Hjelle, S. M., Sulen, A., Øye, O. K., Jørgensen, K. M., McCormack, E., Hollund, B. E., & Gjertsen, B. T. (2012) · Journal of Proteomics · doi:10.1016/j.jprot.2012.07.021 · Cited by 8

Differential forms of p53 in medulloblastoma primary tumors, cell lines and xenografts

Ekström (2010) · International Journal of Oncology · doi:10.3892/ijo.2010.884 · Cited by 8

The Molecular Biology of Cancer

Tobias, E. S. (2013) · Elsevier eBooks · doi:10.1016/b978-0-12-383834-6.00021-5 · Cited by 8

Comparison of the QuantiGene 2.0 Assay and Real-Time RT-PCR in the Detection of p53 Isoform mRNA Expression in Formalin-Fixed Paraffin-Embedded Tissues- A Preliminary Study

Morten, B. C., Scott, R. J., & Avery‐Kiejda, K. A. (2016) · PLoS ONE · doi:10.1371/journal.pone.0165930 · Cited by 8

Amniotic Fluid Cells, Stem Cells, and p53: Can We Stereotype p53 Functions?

Rodrigues, M., Blattner, C., & Stuppia, L. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092236 · Cited by 8

Conservation and implications of eukaryote transcriptional regulatory regions across multiple species

Wan, L., Li, D., Zhang, D., Liu, X., Fu, W. J., Zhu, L., Deng, M., Sun, F., & Qian, M. (2008) · BMC Genomics · doi:10.1186/1471-2164-9-623 · Cited by 8

DEC1 and MIC-1

Qian, Y., Jung, Y.-S., & Chen, X. (2012) · Cell Cycle · doi:10.4161/cc.21962 · Cited by 8

Δ133p53α-mediated inhibition of astrocyte senescence and neurotoxicity as a possible therapeutic approach for neurodegenerative diseases

Horikawa, I., Yamada, L., Harris, B. T., & Harris, C. C. (2025) · Neuroscience · doi:10.1016/j.neuroscience.2025.06.031 · Cited by 7

The Role of p53‐Mediated Cellular Senescence in Idiopathic Pulmonary Fibrosis

Jin, Y., Jiang, M., Bu, W., Zhou, Y., Tang, J., Bao, S., Zhao, R., Zhao, X., & Cheng, D. (2025) · Comprehensive physiology · doi:10.1002/cph4.70041 · Cited by 8

Targeting RNA G-Quadruplexes for Potential Therapeutic Applications

Pandey, S., Agarwala, P., & Maiti, S. (2017) · Topics in medicinal chemistry · doi:10.1007/7355_2016_22 · Cited by 7

It is not all about the alpha: elevated expression of p53β variants is associated with lower probability of survival in a retrospective melanoma cohort

Groen, K., Reinhardt, L. S., Bourdon, J., & Avery‐Kiejda, K. A. (2023) · Cancer Cell International · doi:10.1186/s12935-023-03083-6 · Cited by 7

A Potential Prognostic Gene Signature Associated with p53-Dependent NTRK1 Activation and Increased Survival of Neuroblastoma Patients

Currie, D., Wong, N., Zane, I., Rix, T., Vardakastanis, M., Claxton, A., Ong, K. K. V., Macmorland, W., Poivet, A., Brooks, A., et al. (2024) · Cancers · doi:10.3390/cancers16040722 · Cited by 7

p53 Genetics and Biology in Lung Carcinomas: Insights, Implications and Clinical Applications

Benitez, D. A., Cumplido-Laso, G., Olivera-Gómez, M., Pino, N. D. V.-D., Díaz-Pizarro, A., Mulero‐Navarro, S., Román-García, A., & Carvajal-González, J. M. (2024) · Biomedicines · doi:10.3390/biomedicines12071453 · Cited by 9

Targeting p53 as a Promising Therapeutic Option for Cancer By Re-Activating the Wt Or Mutant p53’s Tumor Suppression

Węsierska‐Gądek, J. (2018) · Future Medicinal Chemistry · doi:10.4155/fmc-2017-0175 · Cited by 7

Regulation of miR-186-YY1 axis by the p53 translational isoform ∆40p53: implications in cell proliferation

Katoch, A., Tripathi, S. K., Pal, A., & Das, S. (2021) · Cell Cycle · doi:10.1080/15384101.2021.1875670 · Cited by 7

Alternative RNA splicing in cancer: what about adult T-cell leukemia?

Tram, J., Mesnard, J.-M., & Péloponèse, J. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.959382 · Cited by 6

The Expression of Pax6 Variants Is Subject to Posttranscriptional Regulation in the Developing Mouse Eyelid

Shi, F., Fan, Y., Zhang, L., Meng, L., Zhi, H., Hu, H., & Lin, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0053919 · Cited by 9

Integrative p53, micro-RNA and Cathepsin Protease Co-Regulatory Expression Networks in Cancer

Soond, S. M., Kozhevnikova, M. V., Townsend, P. A., & Zamyatnin, A. A. (2020) · Cancers · doi:10.3390/cancers12113454 · Cited by 7

Effects of exogenous p53 transfection on the gene expression in the human brain glioma cell line U251

Shu, K., Li, B., Liang, Y., Xie, Y., Zhang, J.-C., & Wei, J.-M. (2006) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2005.12.005 · Cited by 7

The Presence of a Short Form of p53 in Chicken Lymphoblastoid Cell Lines during Apoptosis

Takagi, M., Takeda, T., Asada, Y., Sugimoto, C., Onuma, M., & Ohashi, K. (2006) · Journal of Veterinary Medical Science · doi:10.1292/jvms.68.561 · Cited by 7

G:C > A:T mutations and potential epigenetic regulation of p53 in breast cancer

Kouidou, S., Malousi, A., Kyventidis, A., Fragou, A., & Maglaveras, N. (2007) · Breast Cancer Research and Treatment · doi:10.1007/s10549-007-9514-y · Cited by 7

Evolution of affinity between p53 transactivation domain and MDM2 across the animal kingdom demonstrates high plasticity of motif‐mediated interactions

Mihalič, F., Åberg, E., Farkhondehkish, P., Theys, N., Andersson, E., & Jemth, P. (2023) · Protein Science · doi:10.1002/pro.4684 · Cited by 6

Advances in the diagnosis of colorectal cancer: the application of molecular biomarkers and imaging techniques: a literature review

Huey, A. K. S., Uwishema, O., Mshaymesh, S., Choudhary, K., Salem, F. K., Sengar, A. S., Patel, R. P., Kazan, Z., & Wellington, J. (2024) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000002830 · Cited by 6

Expression of p53β and Δ133p53 isoforms in different gastric tissues.

Ji, W., Zhang, N., Zhang, H., Ma, J., Zhong, H., Jiao, J., & Gao, Z. (2015) · PubMed Central · Cited by 6

DNA signals at isoform promoters

Dai, Z., Xiong, Y., & Dai, X. (2016) · Scientific Reports · doi:10.1038/srep28977 · Cited by 6

The “LINC” between Δ40p53-miRNA Axis in the Regulation of Cellular Homeostasis

Pal, A., Ghosh, P. K., & Das, S. (2023) · Molecular and Cellular Biology · doi:10.1080/10985549.2023.2213147 · Cited by 6

Alternative Transcripts Diversify Genome Function for Phenome Relevance to Health and Diseases

Carrion, S. A., Michal, J. J., & Jiang, Z. (2023) · Genes · doi:10.3390/genes14112051 · Cited by 6

p53 binding to human genome: crowd control navigation in chromatin context

Botcheva, K. (2014) · Frontiers in Genetics · doi:10.3389/fgene.2014.00447 · Cited by 6

Fludarabine nucleoside induces accumulations of p53, p63 and p73 in the nuclei of human B ‐lymphoid cell lines, with cytosolic and mitochondrial increases in p53

Almazi, J. G., Mactier, S., Best, G., Crossett, B., Mulligan, S. P., & Christopherson, R. I. (2012) · PROTEOMICS - CLINICAL APPLICATIONS · doi:10.1002/prca.201200003 · Cited by 6

Advances on mutant p53 research

Li, D. (2008) · Hereditas (Beijing) · doi:10.3724/sp.j.1005.2008.00697 · Cited by 6

AG1031 induces apoptosis through suppressing SIRT1/p53 pathway in human neuroblastoma cells

Fu, J., Zhang, H., Zhang, Y., & Zhang, T. (2018) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-018-3461-2 · Cited by 6

Calpain‐mediated cleavage of p53 in human cytomegalovirus‐infected lung fibroblasts

Chen, Z., Boor, P. J., Finnerty, C. C., Herndon, D. N., & Albrecht, T. (2018) · FASEB BioAdvances · doi:10.1096/fba.1028 · Cited by 6

The characterization of two novel IRF-3 transcripts starting from intron 2 of the wild type of IRF-3

Ren, W., Xu, H., Lu, C., Jin, R., Zou, L., Wang, Y., & Zhou, G. (2010) · Molecular Biology Reports · doi:10.1007/s11033-010-0569-1 · Cited by 6

The Isoforms of the p53 Protein

Khoury, M. P., & Bourdon, J.-C. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000927 · Cited by 191

p53 Isoforms as Modifiers of the p53-Dependent Responses: A Hidden Code?

Bartolomei, L., Pretto, B., Brugnara, S., Sontacchi, A., Dassi, V., Bousrih, A., Damaggio, C., Flangini, F., Bisio, A., & Ciribilli, Y. (2026) · Cancers · doi:10.3390/cancers18071057 · Cited by 3

P53 and cancer

Das, D. (2011)

p53: link to the past, bridge to the futurePreprint

Mills, A. A. (2005) · Genes & Development · doi:10.1101/gad.1362905 · Cited by 81

p53 Family Isoforms

Bourdon, J. (2007) · Current Pharmaceutical Biotechnology · doi:10.2174/138920107783018444 · Cited by 81