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Elevated Mouse Hepatic Betatrophin Expression Does Not Increase Human β-Cell Replication in the Transplant Setting

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Loss of HGF/c-Met Signaling in Pancreatic β-Cells Leads to Incomplete Maternal β-Cell Adaptation and Gestational Diabetes Mellitus

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Distinct Roles of HNF1 Β , HNF1 α , and HNF4 α in Regulating Pancreas Development, Β -Cell Function and Growth

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Down-Regulation of Hepatic HNF4α Gene Expression during Hyperinsulinemia via SREBPs

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Mechanisms in the adaptation of maternal β-cells during pregnancy

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Coordinate Regulation of Lipid Metabolism by Novel Nuclear Receptor Partnerships

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The orphan nuclear receptors at their 25-year reunion

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FoxM1 Is Up-Regulated by Obesity and Stimulates β-Cell Proliferation

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Advancements and challenges in generating accurate animal models of gestational diabetes mellitus

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HNF4α Antagonists Discovered by a High-Throughput Screen for Modulators of the Human Insulin Promoter

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Hepatocyte Nuclear Factor-4α Promotes Gut Neoplasia in Mice and Protects against the Production of Reactive Oxygen Species

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Hepatocyte nuclear factor 4α contributes to an intestinal epithelial phenotype in vitro and plays a partial role in mouse intestinal epithelium differentiation

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Pregnancy‐induced changes in β‐cell function: what are the key players?

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RBM5 Is a Male Germ Cell Splicing Factor and Is Required for Spermatid Differentiation and Male Fertility

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Nuclear Receptor Hepatocyte Nuclear Factor 4α1 Competes with Oncoprotein c-Myc for Control of the p21/WAF1 Promoter

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Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer

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Glucose and aging control the quiescence period that follows pancreatic beta cell replication

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How to make β cells?

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Natural mixtures of POPs affected body weight gain and induced transcription of genes involved in weight regulation and insulin signaling

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The ‘de novo’ DNA methyltransferase Dnmt3b compensates the Dnmt1-deficient intestinal epithelium

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Role of Insulin-Like Growth Factor-Binding Protein 5 (IGFBP5) in Organismal and Pancreatic β-Cell Growth

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Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium

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Deregulation of hepatocyte nuclear factor 4 (HNF4)as a marker of epithelial tumors progression.

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A Brief Review of the Mechanisms of β-Cell Dedifferentiation in Type 2 Diabetes

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Human duct cells contribute to β cell compensation in insulin resistance

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ICA512 signaling enhances pancreatic β-cell proliferation by regulating cyclins D through STATs

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Roles of HNF1α and HNF4α in Pancreatic β-Cells

Yamagata, K. (2014) · Vitamins and hormones · doi:10.1016/b978-0-12-800174-5.00016-8 · Cited by 59 · see citing works

Epistasis of Transcriptomes Reveals Synergism between Transcriptional Activators Hnf1α and Hnf4α

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VHL deficiency augments anthracycline sensitivity of clear cell renal cell carcinomas by down-regulating ALDH2

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Metabolic adaptations to pregnancy in healthy and gestational diabetic pregnancies: the pancreas - placenta Axis

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Adiponectin-Mediated Antilipotoxic Effects in Regenerating Pancreatic Islets

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Pdx-1 Activates Islet α- and β-Cell Proliferation via a Mechanism Regulated by Transient Receptor Potential Cation Channels 3 and 6 and Extracellular Signal-Regulated Kinases 1 and 2

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Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes

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Functional screen of inflammatory bowel disease genes reveals key epithelial functions

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Regulation of beta cell replication

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(Re)generating Human Beta Cells: Status, Pitfalls, and Perspectives

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HNF4α orchestrates a set of 14 genes to down-regulate cell proliferation in kidney cells

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On the origin of the β cellPreprint

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Proteomic Analysis of Native Hepatocyte Nuclear Factor-4α (HNF4α) Isoforms, Phosphorylation Status, and Interactive Cofactors

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Overexpression of Hepatocyte Nuclear Factor-4α Initiates Cell Cycle Entry, but Is not Sufficient to Promote β-Cell Expansion in Human Islets

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Epigenetics and diabetes treatment: an unrealized promise?

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High-throughput Functional Genomics Identifies Regulators of Primary Human Beta Cell Proliferation

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Anakinra and Tocilizumab Enhance Survival and Function of Human Islets during Culture: Implications for Clinical Islet Transplantation

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Piecing together the puzzle of pancreatic islet adaptation in pregnancy

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Pancreatic Stem Cells Remain Unresolved

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Maternal diabetes, programming of beta-cell disorders and intergenerational risk of type 2 diabetes

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Consequences of gestational diabetes to the brain and behavior of the offspring

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Islet-1 Regulates Arx Transcription during Pancreatic Islet α-Cell Development

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Weighing up β-cell mass in mice and humans: Self-renewal, progenitors or stem cells?

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Ductal Malformation and Pancreatitis in Mice Caused by Conditional Jag1 Deletion

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Nuclear Receptor Location Analyses in Mammalian Genomes: From Gene Regulation to Regulatory Networks

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Research Resource: A Dual Proteomic Approach Identifies Regulated Islet Proteins During β-Cell Mass Expansion In Vivo

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Pancreatic prolactin receptor signaling regulates maternal glucose homeostasis

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Anks4b, a Novel Target of HNF4α Protein, Interacts with GRP78 Protein and Regulates Endoplasmic Reticulum Stress-induced Apoptosis in Pancreatic β-Cells

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Stem cells to restore insulin production and cure diabetes

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Loss of Foxd3 Results in Decreased β-Cell Proliferation and Glucose Intolerance During Pregnancy

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Chemical Starting Matter for HNF4α Ligand Discovery and Chemogenomics

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Slow and steady is the key to β‐cell replication

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Maternal diet during pregnancy and adaptive changes in the maternal and fetal pancreas have implications for future metabolic health

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Ginseng Berry Extract Supplementation Improves Age-Related Decline of Insulin Signaling in Mice

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MafB Is Important for Pancreatic β -Cell Maintenance under a MafA-Deficient Condition

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LC‑MS/MS proteomic analysis revealed novel associations of 37 proteins with T2DM and notable upregulation of immunoglobulins

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The protein architecture and allosteric landscape of HNF4α

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Late Cognitive Consequences of Gestational Diabetes to the Offspring, in a New Mouse Model

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Nutriepigenomics and Malnutrition

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Regeneration in Liver and Pancreas: Time to Cut the Umbilical Cord?

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Sfrp5 mediates glucose-induced proliferation in rat pancreatic β-cells

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Pancreatic Stem Cells: From Possible to Probable

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SAT-162 Hepatocyte Nuclear Factor-4α (HNF44α) as a Target to Treat DM

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Overexpression of Hepatocyte Nuclear Factor-4α Initiates Cell Cycle Entry, but Is not Sufficient to Promote β-Cell Expansion in Human Islets

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Hepatocyte Nuclear Factor 4-α (HNF4α) controls the insulin resistance-induced pancreatic β-cell mass expansion

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Roles of HNF1α and HNF4α in Pancreatic β-Cells

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Tissue-specific transcription factor HNF4α inhibits cell proliferation and induces apoptosis in the pancreatic INS-1 β-cell line

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