KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development

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Identification of Jumonji AT-Rich Interactive Domain 1A Inhibitors and Their Effect on Cancer Cells

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Targeting Histone Modifications in Breast Cancer: A Precise Weapon on the Way

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PHF8 Plays an Oncogene Function in Hepatocellular Carcinoma Formation

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Hydroxylation mediates chromatin demethylation

Tsukada, Y.-I. (2012) · The Journal of Biochemistry · doi:10.1093/jb/mvs003 · Cited by 30 · see citing works

Histone deacetylation promotes mouse neural induction by restricting Nodal-dependent mesendoderm fate

Liu, P., Dou, X., Liu, C., Wang, L., Xing, C., Peng, G., Chen, J., Yu, F., Qiao, Y., Song, L., et al. (2015) · Nature Communications · doi:10.1038/ncomms7830 · Cited by 28 · see citing works

Catalysis by KDM6 Histone Demethylases – A Synergy between the Non‐Heme Iron(II) Center, Second Coordination Sphere, and Long‐Range Interactions

Rifayee, S. B. J. S., Chaturvedi, S. S., Warner, C., Wildey, J., White, W., Thompson, M. J., Schofield, C. J., & Christov, C. Z. (2023) · Chemistry - A European Journal · doi:10.1002/chem.202301305 · Cited by 27 · see citing works

Histones, Their Variants and Post-translational Modifications in Zebrafish Development

Cavalieri, V. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00456 · Cited by 26 · see citing works

Emerging epigenetic therapeutics for myeloid leukemia: modulating demethylase activity with ascorbate

Das, A. B., Smith-Díaz, C. C., & Vissers, M. C. M. (2020) · Haematologica · doi:10.3324/haematol.2020.259283 · Cited by 25 · see citing works

Intrinsic regulations in neural fate commitment

Tang, K., Peng, G., Qiao, Y., Song, L., & Jing, N. (2015) · Development Growth & Differentiation · doi:10.1111/dgd.12204 · Cited by 25 · see citing works

Chemical Inhibitors Targeting the Histone Lysine Demethylase Families with Potential for Drug Discovery

Das, N. D., Niwa, H., & Umehara, T. (2023) · Epigenomes · doi:10.3390/epigenomes7010007 · Cited by 25 · see citing works

Histone Demethylase KDM7A Contributes to the Development of Hepatic Steatosis by Targeting Diacylglycerol Acyltransferase 2

Kim, J.-H., Nagappan, A., Jung, D. Y., Suh, N., & Jung, M. H. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222011085 · Cited by 24 · see citing works

JMJD-1.2/PHF8 controls axon guidance by regulating Hedgehog-like signaling

Riveiro, A. R., Mariani, L. L., Malmberg, E., Amendola, P. G., Peltonen, J., Wong, G., & Salcini, A. E. (2017) · Development · doi:10.1242/dev.142695 · Cited by 22 · see citing works

The dual histone demethylase KDM7A promotes neural induction in early chick embryos

Huang, C., Chen, J., Zhang, T., Zhu, Q., Xiang, Y., Chen, C. D., & Jing, N. (2010) · Developmental Dynamics · doi:10.1002/dvdy.22465 · Cited by 22 · see citing works

Epigenetic influences on the developing brain: effects of hormones and nutrition

McCarthy, M. M., & Nugent, B. M. (2015) · Advances in Genomics and Genetics · doi:10.2147/agg.s58625 · Cited by 21 · see citing works

Characterization of the Rx1‐dependent transcriptome during early retinal development

Giudetti, G., Giannaccini, M., Biasci, D., Mariotti, S., Degl’Innocenti, A., Perrotta, M., Barsacchi, G., & Andreazzoli, M. (2014) · Developmental Dynamics · doi:10.1002/dvdy.24145 · Cited by 21 · see citing works

Analysis of Histone Antibody Specificity with Peptide Microarrays

Cornett, E. M., Dickson, B. M., & Rothbart, S. B. (2017) · Journal of Visualized Experiments · doi:10.3791/55912 · Cited by 21 · see citing works

Methyltransferase and demethylase profiling studies during brown adipocyte differentiation

Son, M. J., Kim, W. K., Oh, K., Park, A., Lee, D. S., Han, B., Lee, S. C., & Bae, K. (2016) · BMB Reports · doi:10.5483/bmbrep.2016.49.7.062 · Cited by 20 · see citing works

Molecular Mechanisms of Apical Periodontitis

Mehrazarin, S., Alshaikh, A., & Kang, M. (2016) · Dental Clinics of North America · doi:10.1016/j.cden.2016.08.003 · Cited by 20 · see citing works

Chromatin composition alterations and the critical role of MeCP2 for epigenetic silencing of progesterone receptor-B gene in endometrial cancers

Chu, Y., Wang, Y., Zhang, G., Chen, H., Dowdy, S. C., Xiong, Y., Liu, F., Zhang, R., Li, J., & Jiang, S. W. (2014) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-014-1580-9 · Cited by 19 · see citing works

Mechanistic and structural studies of KDM ‐catalysed demethylation of histone 1 isotype 4 at lysine 26

Walport, L. J., Hopkinson, R. J., Chowdhury, R., Zhang, Y., Bonnici, J., Schiller, R., Kawamura, A., & Schofield, C. J. (2018) · FEBS Letters · doi:10.1002/1873-3468.13231 · Cited by 19 · see citing works

Epigenetic biomarkers as tools for chemical hazard assessment: Gene expression profiling using the model Danio rerio

Torres, T., Ruivo, R., & Santos, M. M. (2021) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2020.144830 · Cited by 18 · see citing works

The histone demethylase PHF8 is a molecular safeguard of the IFNγ response

Asensio-Juan, E., Fueyo, R., Pappa, S., Iacobucci, S., Badosa, C., Lois, S., Balada, M., Bosch‐Presegué, L., Vaquero, A., Gutiérrez, S., et al. (2017) · Nucleic Acids Research · doi:10.1093/nar/gkw1346 · Cited by 18 · see citing works

The histone lysine demethylase KDM7A is required for normal development and first cell lineage specification in porcine embryos

Rissi, V. B., Glanzner, W. G., de Macedo, M. P., Gutierrez, K., Baldassarre, H., Gonçalves, P. B. D., & Bordignon, V. (2019) · Epigenetics · doi:10.1080/15592294.2019.1633864 · Cited by 18 · see citing works

JmjC Lysine Demethylases

Cheng, X., & Trievel, R. C. (2015) · Royal Society of Chemistry eBooks · doi:10.1039/9781782621959-00210 · Cited by 17 · see citing works

Hydroxysafflor yellow A promotes osteogenesis and bone development via epigenetically regulating β-catenin and prevents ovariectomy-induced bone loss

Wang, P., Wang, M., Zhuo, T., Li, Y., Lin, W., Ding, L., Zhang, M., Zhou, C., Zhang, J., Li, G., et al. (2021) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2021.106033 · Cited by 17 · see citing works

Gestational Age Dependence of the Maternal Circulating Long Non-Coding RNA Transcriptome During Normal Pregnancy Highlights Antisense and Pseudogene Transcripts

Kleinbrink, E. L., Gomez‐Lopez, N., Ju, D., Done, B., Goustin, A. S., Tarca, A. L., Romero, R. J., & Lipovich, L. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.760849 · Cited by 17 · see citing works

A novel mutation of SATB2 inhibits odontogenesis of human dental pulp stem cells through Wnt/β-catenin signaling pathway

Xin, T., Li, Q., Bai, R., Zhang, T., Zhou, Y.-H., Zhang, Y., Han, B., & Yang, R. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-021-02660-8 · Cited by 17 · see citing works

JHDM1D and HDAC1–3 mRNA expression levels in peripheral blood mononuclear cells of patients with systemic lupus erythematosus

Nawrocki, M. J., Strugała, A., Piotrowski, P., Wudarski, M., Olesińska, M., & Jagodziński, P. P. (2015) · Zeitschrift für Rheumatologie · doi:10.1007/s00393-015-1619-9 · Cited by 17 · see citing works

Regulators of H3K4 methylation mutated in neurodevelopmental disorders control axon guidance in Caenorhabditis elegans

Nørgaard, S., Attianese, B., Boreggio, L., & Salcini, A. E. (2020) · Development · doi:10.1242/dev.190637 · Cited by 16 · see citing works

Endothelial Brg1 fine-tunes Notch signaling during zebrafish heart regeneration

Xiao, C., Hou, J., Wang, F., Song, Y., Zheng, J., Luo, L., Wang, J., Ding, W., Zhu, X., & Xiong, J. (2023) · npj Regenerative Medicine · doi:10.1038/s41536-023-00293-4 · Cited by 15 · see citing works

Genome-wide identification of Chiari malformation type I associated candidate genes and chromosomal variations

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Distribution and prediction of catalytic domains in 2-oxoglutarate dependent dioxygenases

Kundu, S. (2012) · BMC Research Notes · doi:10.1186/1756-0500-5-410 · Cited by 15 · see citing works

Exploring the potential of histone demethylase inhibition in multi-therapeutic approaches for cancer treatment

Li, D., Liang, H., Wei, Y., Xiao, H., Peng, X., & Pan, W. (2023) · European Journal of Medicinal Chemistry · doi:10.1016/j.ejmech.2023.115999 · Cited by 14 · see citing works

Jumonji family histone demethylases in neural development

Fueyo, R., García, M. A., & Martínez‐Balbás, M. A. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1924-7 · Cited by 14 · see citing works

Glutamate regulates gliosis of BMSCs to promote ENS regeneration through α-KG and H3K9/H3K27 demethylation

Fan, M., Shi, H., Yao, H., Wang, W., Zhang, Y., Jiang, C., & Lin, R. (2022) · Stem Cell Research & Therapy · doi:10.1186/s13287-022-02936-7 · Cited by 13 · see citing works

Histone demethylases in neurodevelopment and neurodegenerative diseases

Wang, H., Guo, B., & Guo, X. (2023) · International Journal of Neuroscience · doi:10.1080/00207454.2023.2276656 · Cited by 13 · see citing works

Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans

Hanqing, Lin, L., Yiqin, Wang, Yanru, Feng, Tian, T., Pu, P., ̆, Y., yu, Y., et al. (2010) · Cell Research

KDM2B is a histone H3K79 demethylase and induces transcriptional repression via sirtuin‐1‐mediated chromatin silencing

Kang, J., Kim, J., Kim, K., Park, J. W., Cho, H., Hahm, J. Y., Chae, Y., Kim, D., Kook, H. Y., Rhee, S., et al. (2018) · The FASEB Journal · doi:10.1096/fj.201800242r · Cited by 97 · see citing works

The histone lysine demethylase KDM7A is required for normal development and first cell lineage specification in porcine embryos

Rissi, V. B., Glanzner, W. G., de Macedo, M. P., Gutierrez, K., Baldassarre, H., Gonçalves, P. B. D., & Bordignon, V. (2019) · Epigenetics · doi:10.1080/15592294.2019.1633864 · Cited by 18 · see citing works

Lysine-specific demethylase 7A (KDM7A): A potential target for disease therapy

Li, C.-Y., Liu, Y., Tao, F., Chen, R.-Y., Shi, J.-J., Lu, J., Yang, G., & Chen, J. (2023) · Biochemical Pharmacology · doi:10.1016/j.bcp.2023.115799 · Cited by 12 · see citing works

Histone demethylases in neurodevelopment and neurodegenerative diseases

Wang, H., Guo, B., & Guo, X. (2023) · International Journal of Neuroscience · doi:10.1080/00207454.2023.2276656 · Cited by 13 · see citing works