CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome.

DNA Repair and Mutagenesis

Friedberg, E. C., Walker, G. C., Siede, W., Wood, R. D., Schultz, R. A., & Ellenberger, T. (2005) · doi:10.1128/9781555816704 · Cited by 5,683

Function and regulation of cullin–RING ubiquitin ligases

Petroski, M. D., & Deshaies, R. J. (2005) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1547 · Cited by 2,148

The Ubiquitin Proteasome System in Neurodegenerative Diseases

Ciechanover, A. J., & Brundin, P. (2003) · Neuron · doi:10.1016/s0896-6273(03)00606-8 · Cited by 1,000

The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage

Groisman, R., Polanowska, J., Kuraoka, I., Sawada, J.-I., Saijo, M., Drapkin, R., Kisselev, A. F., Tanaka, K., & Nakatani, Y. (2003) · Cell · doi:10.1016/s0092-8674(03)00316-7 · Cited by 756

ERCC6, a member of a subfamily of putative helicases, is involved in Cockayne's syndrome and preferential repair of active genes

Troelstra, C., van Gool, A., de Wit, J., Vermeulen, W., Bootsma, D., & Hoeijmakers, J. H. J. (1992) · Cell · doi:10.1016/0092-8674(92)90390-x · Cited by 729

The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH

Henning, K. A., Li, L., Iyer, N., McDaniel, L. D., Reagan, M. S., Legerski, R., Schultz, R. A., Stefanini, M., Lehmann, A. R., Mayne, L. V., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90028-4 · Cited by 507

Mechanisms of transcription-coupled DNA repair

Svejstrup, J. Q. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm703 · Cited by 380

ATP-Dependent Chromatin Remodeling by the Cockayne Syndrome B DNA Repair-Transcription-Coupling Factor

Citterio, E., van den Boom, V., Schnitzler, G. R., Kanaar, R., Bonte, E. J., Kingston, R. E., Hoeijmakers, J. H. J., & Vermeulen, W. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.20.7643-7653.2000 · Cited by 376

Defective Transcription-Coupled Repair in Cockayne Syndrome B Mice Is Associated with Skin Cancer Predisposition

van der Horst, G. T. J., STEEG, H. V., Berg, R. J. W., van Gool, A. J., de Wit, J., Weeda, G., Morreau, H., Beems, R. B., van Kreijl, C. F., de Gruijl, F. R., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80223-8 · Cited by 339

UV-induced ubiquitination of RNA polymerase II: a novel modification deficient in Cockayne syndrome cells.

Bregman, D. B., Halaban, R., van Gool, A. J., Henning, K. A., Friedberg, E. C., & Warren, S. L. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.21.11586 · Cited by 331

Understanding nucleotide excision repair and its roles in cancer and ageing

Marteijn, J. A., Lans, H., Vermeulen, W., & Hoeijmakers, J. H. J. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3822 · Cited by 1,192

DNA repair mechanisms in dividing and non-dividing cells

Iyama, T., & Wilson, D. M. (2013) · DNA Repair · doi:10.1016/j.dnarep.2013.04.015 · Cited by 697

Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery

Angers, S., Li, T., Yi, X., MacCoss, M. J., Moon, R. T., & Zheng, N. (2006) · Nature · doi:10.1038/nature05175 · Cited by 674

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1

Jin, J., Arias, E. E., Chen, J., Harper, J. W., & Walter, J. C. (2006) · Molecular Cell · doi:10.1016/j.molcel.2006.08.010 · Cited by 632

Ubiquitin, Hormones and Biotic Stress in Plants

Dreher, K. A., & Callis, J. (2007) · Annals of Botany · doi:10.1093/aob/mcl255 · Cited by 512

Transcription-coupled nucleotide excision repair in mammalian cells: Molecular mechanisms and biological effects

Fousteri, M., & Mullenders, L. H. (2008) · Cell Research · doi:10.1038/cr.2008.6 · Cited by 487

The Molecular Basis of CRL4DDB2/CSA Ubiquitin Ligase Architecture, Targeting, and Activation

Fischer, E. S., Scrima, A., Böhm, K., Matsumoto, S., Lingaraju, G. M., Faty, M., Yasuda, T., Cavadini, S., Wakasugi, M., Hanaoka, F., et al. (2011) · Cell · doi:10.1016/j.cell.2011.10.035 · Cited by 460

DCAFs, the Missing Link of the CUL4-DDB1 Ubiquitin Ligase

Lee, J., & Zhou, P. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.06.001 · Cited by 460

Sunlight damage to cellular DNA: focus on oxidatively generated lesions

Schuch, A. P., Moreno, N. C., Schuch, N. J., Menck, C. F. M., & Garcia, C. C. M. (2017) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2017.01.029 · Cited by 436

Regulation of the Nrf2–Keap1 Antioxidant Response by the Ubiquitin Proteasome System: An Insight into Cullin-Ring Ubiquitin Ligases

Villeneuve, N. F., Lau, A., & Zhang, D. D. (2010) · Antioxidants and Redox Signaling · doi:10.1089/ars.2010.3211 · Cited by 423

CUL4–DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation

Higa, L. A., Wu, M., Ye, T., Kobayashi, R., Sun, H., & Zhang, H. (2006) · Nature Cell Biology · doi:10.1038/ncb1490 · Cited by 426

DNA repair deficiency in neurodegeneration

Jeppesen, D. K., Bohr, V. A., & Stevnsner, T. (2011) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2011.04.013 · Cited by 374

DNA Repair in Mammalian Cells: Nucleotide excision repair: variations on versatility

Nouspikel, T. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-8737-y · Cited by 330

The DNA damage response to transcription stress

Lans, H., Hoeijmakers, J. H. J., Vermeulen, W., & Marteijn, J. A. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0169-4 · Cited by 321

UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair

Schwertman, P., Lagarou, A., Dekkers, D. H. W., Raams, A., van der Hoek, A. C., Laffeber, C., Hoeijmakers, J. H. J., Demmers, J. A. A., Fousteri, M., Vermeulen, W., et al. (2012) · Nature Genetics · doi:10.1038/ng.2230 · Cited by 279

Mutation update for the CSB / ERCC6 and CSA / ERCC8 genes involved in Cockayne syndrome

Laugel, V., Dalloz, C., Durand, M., Sauvanaud, F., Kristensen, U., Vincent, M., Pasquier, L., Odent, S., Cormier‐Daire, V., Gener, B., et al. (2009) · Human Mutation · doi:10.1002/humu.21154 · Cited by 238

A promiscuous α-helical motif anchors viral hijackers and substrate receptors to the CUL4–DDB1 ubiquitin ligase machinery

Li, T., Robert, E. I., Breugel, P. C. V., Strubin, M., & Zheng, N. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1719 · Cited by 223

Mutations in UVSSA cause UV-sensitive syndrome and destabilize ERCC6 in transcription-coupled DNA repair.

Zhang, X., Horibata, K., Saijo, M., Ishigami, C., Ukai, A., Kanno, S.-I., Tahara, H., Neilan, E. G., Honma, M., Nohmi, T., et al. (2012) · Nature Genetics · doi:10.1038/ng.2228 · Cited by 201

Multiomic Analysis of the UV-Induced DNA Damage Response

Boeing, S., Williamson, L. M., Encheva, V., Gori, I., Saunders, R. E., Instrell, R., Aygün, O., Rodríguez‐Martínez, M., Weems, J. C., Kelly, G. P., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.04.047 · Cited by 201

Cell cycle–dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

Kim, J. M., Kee, Y., Gurtan, A. M., & D’Andrea, A. D. (2008) · Blood · doi:10.1182/blood-2007-09-113092 · Cited by 199

CUL4A Abrogation Augments DNA Damage Response and Protection against Skin Carcinogenesis

Liu, L., Lee, S. B., Zhang, J., Peters, S. B., Hannah, J., Zhang, Y., Yin, Y., Koff, A., Ma, L., & Zhou, P. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.04.020 · Cited by 188

Mammalian Transcription-Coupled Excision Repair

Vermeulen, W., & Fousteri, M. (2013) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a012625 · Cited by 184

The cooperative action of CSB, CSA, and UVSSA target TFIIH to DNA damage-stalled RNA polymerase II

van der Weegen, Y., Golan-Berman, H., Mevissen, T. E. T., Apelt, K., González‐Prieto, R., Goedhart, J., Heilbrun, E. E., Vertegaal, A. C. O., van den Heuvel, D., Walter, J. C., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-15903-8 · Cited by 177

Teratogenic effects of thalidomide: molecular mechanisms

Ito, T., Ando, H., & Handa, H. (2011) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-010-0619-9 · Cited by 187

DNA damage response and transcription

Lagerwerf, S., Vrouwe, M. G., Overmeer, R., Fousteri, M. I., & Mullenders, L. H. F. (2011) · DNA repair · doi:10.1016/j.dnarep.2011.04.024 · Cited by 165

Deletion of DDB1 in Mouse Brain and Lens Leads to p53-Dependent Elimination of Proliferating Cells

Cang, Y., Zhang, J., Nicholas, S. A., Bastien, J., Li, B., Zhou, P., & Goff, S. P. (2006) · Cell · doi:10.1016/j.cell.2006.09.045 · Cited by 152

Structural basis of human transcription–DNA repair coupling

Kokić, G., Wagner, F., Chernev, A., Urlaub, H., & Cramer, P. (2021) · Nature · doi:10.1038/s41586-021-03906-4 · Cited by 139

DNA damage during the G0/G1 phase triggers RNA-templated, Cockayne syndrome B-dependent homologous recombination

Wei, L., Nakajima, S., Böhm, S., Bernstein, K. A., Shen, Z., Tsang, M., Levine, A. S., & Lan, L. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1507105112 · Cited by 147

The Cellular Response to Transcription-Blocking DNA Damage

Gregersen, L. H., & Svejstrup, J. Q. (2018) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2018.02.010 · Cited by 150

Ubiquitin-binding domains and their role in the DNA damage response

Hofmann, K. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.01.003 · Cited by 142

CRL4Cdt2

Abbas, T., & Dutta, A. (2011) · Cell Cycle · doi:10.4161/cc.10.2.14530 · Cited by 147

A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage

Nardò, T., Oneda, R., Spivak, G., Vaz, B., Mortier, L., Thomas, P., Orioli, D., Laugel, V., Stary, A., Hanawalt, P. C., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0902113106 · Cited by 140

A Ubiquitin-Binding Domain in Cockayne Syndrome B Required for Transcription-Coupled Nucleotide Excision Repair

Anindya, R., Mari, P., Kristensen, U., Kool, H., Giglia‐Mari, G., Mullenders, L. H. F., Fousteri, M. I., Vermeulen, W., Egly, J., & Svejstrup, J. Q. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.04.017 · Cited by 133

Stealing the spotlight: CUL4-DDB1 ubiquitin ligase docks WD40-repeat proteins to destroy.

Higa, L. A., & Zhang, H. (2007) · Cell Division · doi:10.1186/1747-1028-2-5 · Cited by 126

DDB1 Targets Chk1 to the Cul4 E3 Ligase Complex in Normal Cycling Cells and in Cells Experiencing Replication Stress

Leung‐Pineda, V., Huh, J., & Piwnica-Worms, H. M. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-3382 · Cited by 130

Mechanisms of Disease: DNA repair defects and neurological disease

Subba Rao, K. (2007) · Nature Clinical Practice Neurology · doi:10.1038/ncpneuro0448 · Cited by 121

USP7 Is a Master Regulator of Genome Stability

Valles, G. J., Bezsonova, I., Woodgate, R., & Ashton, N. W. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00717 · Cited by 114

Transcription-Coupled Nucleotide Excision Repair and the Transcriptional Response to UV-Induced DNA Damage

Moreno, N. N., Olthof, A. M., & Svejstrup, J. Q. (2023) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-052621-091205 · Cited by 119

Ubiquitin proteasome system (UPS): what can chromatin do for you?

O’Connell, B. C., & Harper, J. W. (2007) · Current Opinion in Cell Biology · doi:10.1016/j.ceb.2007.02.014 · Cited by 115

Distinct and overlapping functions of the cullin E3 ligase scaffolding proteins CUL4A and CUL4B

Hannah, J., & Zhou, P. (2015) · Gene · doi:10.1016/j.gene.2015.08.064 · Cited by 112

Contending with transcriptional arrest during RNAPII transcript elongation

Svejstrup, J. Q. (2007) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2007.02.005 · Cited by 107

Transcription-Coupled DNA Repair: From Mechanism to Human Disorder

van den Heuvel, D., van der Weegen, Y., Boer, D. E. C., Ogi, T., & Luijsterburg, M. S. (2021) · Trends in Cell Biology · doi:10.1016/j.tcb.2021.02.007 · Cited by 105

Isolation of XAB2 Complex Involved in Pre-mRNA Splicing, Transcription, and Transcription-coupled Repair

Kuraoka, I., Ito, S., Wada, T., Hayashida, M., Lee, L., Saijo, M., Nakatsu, Y., Matsumoto, M., Matsunaga, T., Handa, H., et al. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m706647200 · Cited by 102

UV-Induced Association of the CSB Remodeling Protein with Chromatin Requires ATP-Dependent Relief of N-Terminal Autorepression

Lake, R. J., Geyko, A., Hemashettar, G., Zhao, Y., & Fan, H.-Y. (2010) · Molecular Cell · doi:10.1016/j.molcel.2009.10.027 · Cited by 107

Regulation of damage recognition in mammalian global genomic nucleotide excision repair

Sugasawa, K. (2009) · Mutation research. Fundamental and molecular mechanisms of mutagenesis · doi:10.1016/j.mrfmmm.2009.08.004 · Cited by 102

Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability

Geijer, M. E., Zhou, D., Selvam, K., Steurer, B., Mukherjee, C., Evers, B., Cugusi, S., van Toorn, M., van der Woude, M., Janssens, R. C., et al. (2021) · Nature Cell Biology · doi:10.1038/s41556-021-00692-z · Cited by 91

An Abundant Evolutionarily Conserved CSB-PiggyBac Fusion Protein Expressed in Cockayne Syndrome

Newman, J. C., Bailey, A. D., Fan, H.-Y., Pavelitz, T., & Weiner, A. M. (2008) · PLoS Genetics · doi:10.1371/journal.pgen.1000031 · Cited by 91

The Involvement of DNA-Damage and -Repair Defects in Neurological Dysfunction

Kulkarni, A., & Wilson, D. M. (2008) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2008.01.009 · Cited by 89

Overview of DNA Repair in Trypanosoma cruzi, Trypanosoma brucei, and Leishmania major

Passos-Silva, D. G., Rajão, M. A., de Aguiar, P. H. N., Vieira‐da‐Rocha, J. P., Machado, C. R., & Furtado, C. (2010) · Journal of Nucleic Acids · doi:10.4061/2010/840768 · Cited by 88

Global and transcription-coupled repair of 8-oxoG is initiated by nucleotide excision repair proteins

Kumar, N., Theil, A. F., Roginskaya, V. Y., Ali, Y., Calderon, M. J., Watkins, S. C., Barnes, R. P., Opresko, P. L., Pines, A., Lans, H., et al. (2022) · Nature Communications · doi:10.1038/s41467-022-28642-9 · Cited by 79

PCNA-coupled p21 degradation after DNA damage: The exception that confirms the rule?

Soria, G., & Gottifredi, V. (2010) · DNA repair · doi:10.1016/j.dnarep.2009.12.003 · Cited by 85

Role of Deubiquitinating Enzymes in DNA Repair

Kee, Y., & Huang, T. T. (2015) · Molecular and Cellular Biology · doi:10.1128/mcb.00847-15 · Cited by 81

Molecular Regulation of UV ‐Induced DNA Repair

Shah, P., & He, Y. (2015) · Photochemistry and Photobiology · doi:10.1111/php.12406 · Cited by 75

The DDB1a interacting proteins ATCSA-1 and DDB2 are critical factors for UV-B tolerance and genomic integrity in Arabidopsis thaliana

Biedermann, S., & Hellmann, H. A. (2010) · The Plant Journal · doi:10.1111/j.1365-313x.2010.04157.x · Cited by 78

The Multifunctions of WD40 Proteins in Genome Integrity and Cell Cycle Progression

Zhang, C., & Zhang, F. (2015) · Journal of Genomics · doi:10.7150/jgen.11015 · Cited by 74

Aberrations in DNA repair pathways in cancer and therapeutic significances

Motegi, A., Masutani, M., Yoshioka, K., & Bessho, T. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.02.005 · Cited by 76

Cockayne syndrome group B (CSB) protein: At the crossroads of transcriptional networks

Vélez-Cruz, R., & Egly, J. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.03.004 · Cited by 74

The interface between transcription and mechanisms maintaining genome integrity

Svejstrup, J. Q. (2010) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2010.02.001 · Cited by 73

Damage control: DNA repair, transcription, and the ubiquitin–proteasome system

Daulny, A., & Tansey, W. P. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.01.017 · Cited by 73

Cdt1 degradation to prevent DNA re-replication: conserved and non-conserved pathways

Kim, Y., & Kipreos, E. T. (2007) · Cell Division · doi:10.1186/1747-1028-2-18 · Cited by 74

Regulated degradation of FANCM in the Fanconi anemia pathway during mitosisPreprint

Kee, Y., Kim, J. M., & D’Andrea, A. D. (2009) · Genes & Development · doi:10.1101/gad.1761309 · Cited by 74

Nucleotide excision repair and neurological diseases

Nouspikel, T. (2008) · DNA repair · doi:10.1016/j.dnarep.2008.03.015 · Cited by 73

KIAA1530 Protein Is Recruited by Cockayne Syndrome Complementation Group Protein A (CSA) to Participate in Transcription-coupled Repair (TCR)

Fei, J., & Chen, J. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.398131 · Cited by 70

Mechanism of immunomodulatory drugs' action in the treatment of multiple myeloma

Chang, X.-B., Zhu, Y., Shi, C., & Stewart, A. K. (2013) · Acta Biochimica et Biophysica Sinica · doi:10.1093/abbs/gmt142 · Cited by 72

Structural basis of DNA lesion recognition for eukaryotic transcription-coupled nucleotide excision repair

Wang, W., Xu, J., Chong, J. P. C., & Wang, D. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.08.006 · Cited by 68

Regulation of DNA damage response pathways by the cullin-RING ubiquitin ligases

Hannah, J., & Zhou, P. (2009) · DNA repair · doi:10.1016/j.dnarep.2009.01.011 · Cited by 65

Current and emerging roles of Cockayne syndrome group B (CSB) protein

Tiwari, V., Baptiste, B. A., Okur, M. N., & Bohr, V. A. (2021) · Nucleic Acids Research · doi:10.1093/nar/gkab085 · Cited by 64

DDB1 is essential for genomic stability in developing epidermis

Cang, Y., Zhang, J., Nicholas, S. A., Kim, A. L., Zhou, P., & Goff, S. P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0611311104 · Cited by 60

What happens at the lesion does not stay at the lesion: Transcription-coupled nucleotide excision repair and the effects of DNA damage on transcription in cis and trans

Geijer, M. E., & Marteijn, J. A. F. (2018) · DNA repair · doi:10.1016/j.dnarep.2018.08.007 · Cited by 64

CSA and CSB proteins interact with p53 and regulate its Mdm2-dependent ubiquitination

Latini, P., Frontini, M., Caputo, M., Gregáň, J., Čipák, L., Filippi, S., Kumar, V., Vélez-Cruz, R., Stefanini, M., & Proietti‐De‐Santis, L. (2011) · Cell Cycle · doi:10.4161/cc.10.21.17905 · Cited by 60

Formation and Recognition of UV-Induced DNA Damage within Genome Complexity

Berens, P. J. T., & Molinier, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21186689 · Cited by 59

Cockayne syndrome pathogenesis: Lessons from mouse models

Jaarsma, D., van der Pluijm, I., van der Horst, G. T. J., & Hoeijmakers, J. H. J. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.04.003 · Cited by 59

Detecting UV‐lesions in the genome: The modular CRL4 ubiquitin ligase does it best!

Scrima, A., Fischer, E. S., Lingaraju, G. M., Böhm, K., Cavadini, S., & Thomä, N. H. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.04.064 · Cited by 66

The role of Cockayne syndrome group A (CSA) protein in transcription-coupled nucleotide excision repair

Saijo, M. (2013) · Mechanisms of Ageing and Development · doi:10.1016/j.mad.2013.03.008 · Cited by 54

The Caenorhabditis elegans Replication Licensing Factor CDT-1 Is Targeted for Degradation by the CUL-4/DDB-1 Complex

Kim, Y., & Kipreos, E. T. (2006) · Molecular and Cellular Biology · doi:10.1128/mcb.00736-06 · Cited by 56

Cockayne Syndrome: The many challenges and approaches to understand a multifaceted disease

Vessoni, A. T., Guerra, C. C. C., Kajitani, G. S., Nascimento, L. L. S., & Garcia, C. C. M. (2020) · Genetics and Molecular Biology · doi:10.1590/1678-4685-gmb-2019-0085 · Cited by 57

Transcription-coupled DNA–protein crosslink repair by CSB and CRL4CSA-mediated degradation

van Sluis, M., Yu, Q. S., van der Woude, M., Gonzalo-Hansen, C., Dealy, S., Janssens, R. C., Somsen, H. B., Ramadhin, A. R., Dekkers, D. H. W., Wienecke, H. L., et al. (2024) · Nature Cell Biology · doi:10.1038/s41556-024-01394-y · Cited by 55

UVR8 mediated plant protective responses under low UV-B radiation leading to photosynthetic acclimation

Singh, S., Agrawal, S. B., & Agrawal, M. (2014) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2014.03.026 · Cited by 51

Nedd8-Activating Enzyme Inhibitor MLN4924 Provides Synergy with Mitomycin C through Interactions with ATR, BRCA1/BRCA2, and Chromatin Dynamics Pathways

Garcia, K., Blank, J. L., Bouck, D. C., Liu, X. J., Sappal, D. S., Hather, G., Cosmopoulos, K., Thomas, M. P., Kuranda, M., Pickard, M. D., et al. (2014) · Molecular Cancer Therapeutics · doi:10.1158/1535-7163.mct-13-0634 · Cited by 52

Dealing with transcription-blocking DNA damage: Repair mechanisms, RNA polymerase II processing and human disorders

Jia, N., Guo, C., Nakazawa, Y., van den Heuvel, D., Luijsterburg, M. S., & Ogi, T. (2021) · DNA repair · doi:10.1016/j.dnarep.2021.103192 · Cited by 50

DNA damage mediated transcription arrest: Step back to go forward

Mullenders, L. H. F. (2015) · DNA repair · doi:10.1016/j.dnarep.2015.09.005 · Cited by 51

The Role of the COP9 Signalosome and Neddylation in DNA Damage Signaling and Repair

Chung, D., & Dellaire, G. (2015) · Biomolecules · doi:10.3390/biom5042388 · Cited by 50

TRiC controls transcription resumption after UV damage by regulating Cockayne syndrome protein A

Pines, A., Dijk, M., Makowski, M. M., Meulenbroek, E. M., Vrouwe, M. G., van der Weegen, Y., Baltissen, M. P. A., French, P. J., van Royen, M. E., Luijsterburg, M. S., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-03484-6 · Cited by 48

Nucleotide excision repair deficient mouse models and neurological disease

Niedernhofer, L. J. (2008) · DNA repair · doi:10.1016/j.dnarep.2007.12.006 · Cited by 50

The 3' processing factor CstF functions in the DNA repair response

Mirkin, N., Fonseca, D., Mohammed, S., Cevher, M. A., Manley, J. L., & Kleiman, F. E. (2008) · Nucleic Acids Research · doi:10.1093/nar/gkn005 · Cited by 52

UVSSA and USP7, a new couple in transcription-coupled DNA repair

Schwertman, P., Vermeulen, W., & Marteijn, J. A. (2013) · Chromosoma · doi:10.1007/s00412-013-0420-2 · Cited by 49

The role and mechanism of CRL4 E3 ubiquitin ligase in cancer and its potential therapy implications

Sang, Y., Fan, Y., & Ren, X. (2015) · Oncotarget · doi:10.18632/oncotarget.6052 · Cited by 50

Human Immunodeficiency Virus Type 1 Vpr Links Proteasomal Degradation and Checkpoint Activation

DeHart, J. L., & Planelles, V. (2007) · Journal of Virology · doi:10.1128/jvi.01628-07 · Cited by 49

BRCA1 contributes to transcription-coupled repair of DNA damage through polyubiquitination and degradation of Cockayne syndrome B protein.

Wei, L., Lan, L., Yasui, A., Tanaka, K., Saijo, M., Matsuzawa, A., Kashiwagi, R., Maseki, E., Hu, Y., Parvin, J. D., et al. (2011) · Cancer Science · doi:10.1111/j.1349-7006.2011.02037.x · Cited by 48

Hepatocyte-specific deletion of DDB1 induces liver regeneration and tumorigenesis

Yamaji, S., Zhang, M., Zhang, J., Endo, Y., Бибикова, Е., Goff, S. P., & Cang, Y. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1015793108 · Cited by 47

Arabidopsis Cockayne Syndrome A-Like Proteins 1A and 1B Form a Complex with CULLIN4 and Damage DNA Binding Protein 1A and Regulate the Response to UV Irradiation

Zhang, C., Guo, H., Zhang, J., Guo, G., Schumaker, K. S., & Guo, Y. (2010) · The Plant Cell · doi:10.1105/tpc.110.073973 · Cited by 46

Promoters of ASCL1‐ and NEUROD1‐dependent genes are specific targets of lurbinectedin in SCLC cells

Costanzo, F., Martínez, M., Núñez, G. S., Díaz‐Hernandéz, J. I., Robles, C. M. G., Pérez, J. D., Compe, E., Ricci, R., Li, T., Coin, F., et al. (2022) · EMBO Molecular Medicine · doi:10.15252/emmm.202114841 · Cited by 45

DCAF26, an Adaptor Protein of Cul4-Based E3, Is Essential for DNA Methylation in Neurospora crassa

Xu, H., Wang, J., Hu, Q., Quan, Y., Chen, H., Cao, Y., Li, C., Wang, Y., & He, Q. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001132 · Cited by 45

Initiation of DNA interstrand cross‐link repair in mammalian cells

Hlavin, E. M., Smeaton, M. B., & Miller, P. S. (2010) · Environmental and Molecular Mutagenesis · doi:10.1002/em.20559 · Cited by 46

COP9 signalosome function in the DDR

Hannß, R., & Dubiel, W. (2011) · FEBS Letters · doi:10.1016/j.febslet.2011.04.027 · Cited by 48

Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation

Park, J.-M., & Kang, T.-H. (2016) · International Journal of Molecular Sciences · doi:10.3390/ijms17111840 · Cited by 44

Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation

Okur, M. N., Lee, J., Osmani, W. A., Kimura, R., Demarest, T. G., Croteau, D. L., & Bohr, V. A. (2019) · Nucleic Acids Research · doi:10.1093/nar/gkz1242 · Cited by 44

Transcription coupled repair at the interface between transcription elongation and mRNP biogenesis

Gaillard, H., & Aguilera, A. (2012) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2012.09.008 · Cited by 46

Nucleotide excision repair leaves a mark on chromatin: DNA damage detection in nucleosomes

Apelt, K., Lans, H., Schärer, O. D., & Luijsterburg, M. S. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03984-7 · Cited by 45

Nucleotide excision repair and the ubiquitin proteasome pathway—Do all roads lead to Rome?

Reed, S. H., & Gillette, T. G. (2006) · DNA repair · doi:10.1016/j.dnarep.2006.10.026 · Cited by 44

CSA-dependent proteasomal degradation of CSB establishes a link between complementation factors of the Cockayne syndrome.

Groisman, R., Kisselev, A. F., Tanaka, K., & Nakatani, Y. (2004) · The Japan Radiation Research Society Annual Meeting Abstracts The 47th Annual Meeting of The Japan Radiation Research Society · doi:10.11513/jrrsabst.2004.0_55_5

Structural Biology of Cockayne Syndrom e Proteins, Their Interactions and Insights into DNA Repair Mechanisms

Ahmad, S. I. (2009) · CRC Press eBooks · doi:10.1201/9781498712705-12

Cockayne Syndrome Group B Cellular and Biochemical Functions

Licht, C. L., Stevnsner, T., & Bohr, V. A. (2003) · The American Journal of Human Genetics · doi:10.1086/380399 · Cited by 161

Multisystem analyses of two Cockayne syndrome associated proteins CSA and CSB reveal shared and unique functions

Wu, Z., Zhu, X., Qian, Y., Xu, Y., & Wang, Y. (2019) · DNA repair · doi:10.1016/j.dnarep.2019.102696 · Cited by 6

CS proteins and ubiquitination: orchestrating DNA repair with transcription and cell division

Costanzo, F., Paccosi, E., Proietti‐De‐Santis, L., & Egly, J. (2024) · Trends in Cell Biology · doi:10.1016/j.tcb.2024.06.002 · Cited by 14