The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells

Bracken, Adrian P., Kleine-Kohlbrecher, Daniela, Dietrich, Nikolaj, Pasini, Diego, Gargiulo, Gaetano, Beekman, Chantal, Theilgaard-Mönch, Kim, Minucci, Saverio +4 more·2007·Genes & Development

Cited by (850)

Items 801–850 of 850

  1. Protein kinase D1 phosphorylates CBX8 to facilitate the disassociation of PRC1 complex from p16 promoter and promotes cell senescence
    Yuanyuan Su, Yao Liang, Chenzhong Xu, Na Zhang, Doudou Liu, Guodong Li, Tanjun Tong, Jun Chen · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
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  3. Functional characterization of histidine domain-protein tyrosine phosphatase (HD-PTP) in tumor development
    Sanaz Manteghi · 2016
  4. フリーター五右衛門(2)コガネムシの羽音
    昌典 神田 · 2005 · 文蔵
  5. Age-Associated Features of the Expression Level of Apoptosis Markers in Cardiomyocytes of Patients with Dilated Cardiomyopathy
    K. Kravchenko, Kirill Lenarovich Kozlov, А. О. Дробинцева, Д С Медведев, Victoria Olegovna Polyakova · 2022 · Advances in Gerontology
  6. Interplay between Polycomb PCGF protein interactomes revealed by screening under endogenous conditions
    Nayla Munawar, Kieran J. Wynne, Giorgio Oliviero · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  7. Resolving Geroplasticity to the Balance of Rejuvenins and Geriatrins
    SIAMAK S. TABIBZADEH · 2022 · Aging and Disease
  8. Effects of histone 3.3K27M-mutation on CREB binding protein (CBP/p300)- and bromodomain and extra terminal domain (BET) protein- mediated gene regulation in diffuse intrinsic pontine gliomas (DIPG)
    Klaudia Kubiak · 2023
  9. Reorganization of the Senescent Genome via Spatial CTCF Clustering
    Spiros Palikyras · 2023
  10. PRC1 Protein Subcomplexes Architecture: Focus on the Interplay between Distinct PCGF Subunits in Protein Interaction Networks
    Nayla Munawar, Kieran J. Wynne, Giorgio Oliviero · 2024 · International Journal of Molecular Sciences
  11. Prostate Cancer and EZH2 Signaling
    Mohammed Kavei, Siavash Seifollahy Fakhr, Afsaneh Mousaei, Bita Ghaffari, Nazanin Fatemeh Fadavinia, Tara Noroozi Yeganeh, Nasim Ebrahimi, Mostafa Haji-Fatahaliha, Amir Reza Aref · 2024 · Springer eBooks
  12. Genetic Determinants of Cancer Susceptibility
    Robin Lesley Williams, Kyle Brandon Williams · 2024 · Elsevier eBooks
  13. Evolutionary conserved reciprocal senescence and tumor suppressor signals limit lifetime cancer
    Liqiong Liu, Stephani A. Davis, Shamila Yusuff, Ann Strange, Yonghua Zhuang, Prasanna Kumar Vaddi, Kathleen Flaherty, Kelly Jara, Joseph Kramer, Christine Archer et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  14. iPSC-derived NF1 - CDKN2A -PRC2 deficient neural crest mimics MPNST glial-to-neuro-mesenchymal transition and uncover new therapeutic opportunities
    Itziar Uriarte-Arrazola, Miriam Magallón‐Lorenz, Juana Fernández‐Rodríguez, Jiajing Zhang, Emily Lee, Sara Ortega‐Bertran, Edgar Creus‐Bachiller, Judit Farrés-Casas, Kelli M. Wilson, Crystal McKnight et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  15. The pseudogene RPS27AP5 expresses ubiquitin and ribosomal protein variants with potential roles in ribosome function
    Anna Meller, Jennifer Raisch, Dominique Lévesque, Étienne Fafard-Couture, Michelle S. Scott, Xavier Roucou, François‐Michel Boisvert · 2025 · Biochemistry and Cell Biology
  16. Phosphorylation of CBX8 by PKD1 suppresses PRC1 activity and promotes cell senescence
    Zhiqiang Fang, Doudou Liu, Yuanyuan Su, Fengxin Hao, Ruodong Qin, Guodong Li, Jun Chen · 2025 · Oncogene
  17. Malignant Rhabdoid Tumor: Epigenetic Mechanism of Tumorogenesis
    Sima Kheradmand Kia · 2015 · Springer eBooks
  18. CHD8, a novel ATP-dependent chromatin remodeling enzyme
    Brandi A. Thompson · 2009 · Deep Blue (University of Michigan)
  19. Additional file 1 of Bmi-1 alleviates adventitial fibroblast senescence by eliminating ROS in pulmonary hypertension
    Li, Kai, Li, Yan, Yu, Youjia, Ding, Jingjing, Huang, Huijie, Chu, Chunyan, Hu, Li, Yu, Yanfang, Cao, Yue, Xu, Peng et al. · 2021 · Figshare
  20. Plasminogen Activator Inhibitor 1, Cell Senescence, and Aging-Related Diseases
    Rui-Ming Liu, Mary F. Nakamya · 2026 · Cells
  21. Fonction différentielle des protéines du groupe Polycomb durant le développement de la drosophile
    Samy Sakr · 2011
  22. Les cellules sénecentes comme niche de survie : rôle de la voie TSP1-CD47
    Marie Moreau · 2017 · theses.fr (ABES)
  23. Pharmacogenomic and High-Throughput Data Analysis to Overcome Triple Negative Breast Cancers Drug Resistance
    Benjamin Sadacca · 2017 · theses.fr (ABES)
  24. Altérations épigénétiques des cellules souches musculaires au cours du vieillissement naturel : implications dans la sarcopénie
    Delphine Bauer · 2017 · theses.fr (ABES)
  25. Etude de l'implication de mécanismes épigénétiques dans la physiopathologie du myélome multiple et dans la différenciation plasmocytaire normale
    Laurie Herviou · 2018 · theses.fr (ABES)
  26. TP53INP1 et PLZF : acteurs du vieillissement dans l’hématopoïèse
    Bochra Zidi · 2019
  27. Applying Systems Biology and Multi-layered Profiling Towards a Comprehensive Understanding of Cell Aging
    José Américo Nabuco Leva Ferreira de Freitas · 2020 · theses.fr (ABES)
  28. Caractérisation de la sénescence des cardiomyocytes et identification de marqueurs associés
    Damien Maggiorani · 2017 · theses.fr (ABES)
  29. Révéler le lien entre la sénescence cellulaire et la pathologie de l'arthrose : un rôle des cellules souches mésenchymateuses et du facteur Chi3L1
    Yassin Tachikart · 2019 · theses.fr (ABES)
  30. Comprendre les mécanismes d’action d’Hsp27 conduisant à la résistance à la castration des cancers de la prostate
    Chaïma Cherif · 2019
  31. Identification of molecular players essential to the anti‐leukemic effect of anti-CD3 mAbs in T cell acute lymphoblastic leukemia
    Benedetta Zaniboni · 2020
  32. Etudes des mécanismes d'action de l'interféron alpha associé au trioxyde d'arsenic dans un modèle de néoplasie myéloproliférative JAK2 V617F.
    Nabih Maslah · 2020 · theses.fr (ABES)
  33. Metabolic homeostasis and regulatory mechanisms of cellular senescence : roles of ITPR2-mediated calcium fluxes and mevalonate pathway
    Dorian V. Ziegler · 2020
  34. Impact comportemental et épigénétique à long terme d’une exposition chronique au stress en milieu de vie chez la souris et effet d’un traitement d’iHDAC
    Kyrian Nicolay-Kritter · 2021 · theses.fr (ABES)
  35. L’échappement à la sénescence induite par chimiothérapie : Un nouveau rôle de la protéine AGR2
    Amine Maarouf · 2021 · theses.fr (ABES)
  36. Rôle du calcium et de son homéostasie dans la sénescence cellulaire et ses effets paracrines : implication de la protéine tamponnant le calcium, CALB1
    Clotilde Raynard · 2021
  37. Identification of Biomarkers Associated With the Combination of Immunotherapy and Anti-Angiogenic Drugs in the Treatment of Mesothelioma : Translational Analyses of the PEMBIB Clinical Trial Combining the Anti-PD1 Monoclonal Antibody Embrolizumab and the Anti-Angiogenic Tyrosine Kinase Inhibitor Nintedanib
    François‐Xavier Danlos · 2021 · theses.fr (ABES)
  38. Rôles de très longs ARNs non codants intergéniques dans la réorganisation 3D du génome au cours de la sénescence
    Julien Ouvrard · 2023 · theses.fr (ABES)
  39. Physiopathological mechanisms leading to two congenital thrombocytopenias, congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia 2 (THC2)
    Francesca Basso‐Valentina · 2021 · theses.fr (ABES)
  40. Régulation de l’expression d’UNC5A par l’axe OGT/EZH2 : une nouvelle connexion entre nutrition, épigénétique et cancer colorectal ?
    Amélie Decourcelle · 2020 · theses.fr (ABES)
  41. Innovative approaches for managing relapsed or refractory peripheral T-cell lymphoma
    Brian T. Grainger, Joshua M. L. Casan, Chathuri Abeyakoon, Salvia Sanjay Jain, Henry Miles Prince · 2026 · Expert Opinion on Pharmacotherapy
  42. ChIPmentation-based mapping of histone modifications in aging: Experimental design and analytical considerations
    Amalanandan Johna, Sreedarsanam Sreya, Tiyas Sengupta, Pavithra Elumalai, Avik Sengupta, Rahul Kumar, Mayilaadumveettil Nishana · 2026 · Methods in enzymology on CD-ROM/Methods in enzymology
  43. Induced pluripotent stem cell–derived models of malignant nerve sheath tumor progression mimic glial to neuro-mesenchymal transition and uncover therapeutic opportunities
    Itziar Uriarte-Arrazola, Miriam Magallón‐Lorenz, Juana Fernández‐Rodríguez, Jiajing Zhang, Emily Lee, Sara Ortega‐Bertran, Edgar Creus‐Bachiller, Judit Farrés-Casas, Kelli M. Wilson, Crystal G. McKnight et al. · 2026 · Nature Communications
  44. Psc and Su(z)2 safeguard intestinal stem cell identity and prevent chinmo-dependent tumorigenesis
    Ruxue Wei, Haimeng Yu, Qingyu Sun, Yongchao Zhang, Yaxin Yu, Rongwen Xi · 2026 · EMBO Reports
  45. Chromatin topology and distal elements underlie divergent cell-type-specific regulation of 9p21 locus cell cycle genes
    Elena Torlai Triglia, Tyler E. Miller, Neva C. Durand, Kyung Lock Kim, Salvador Casaní-Galdón, Joshua D’Antonio, Nauman Javed, Alessandro Paz Hernandez, Ayush Raman, Anna J. Cruz et al. · 2026 · Cell Genomics
  46. Beyond senescence entry: Individual-cell fates, population outcomes and therapeutic implications in ageing and disease
    Guosong Wang, Yang Meng, Junhong Han · 2026 · Ageing Research Reviews
  47. Therapy induced senescence promotes immunogenicity in acute myeloid Leukemia through reduced EZH2 activity
    Diego Gilioli, Simona Fusco, Teresa Tavella, Tatiana Volpari, Antonella Santoro, Martin Schönlein, Kety Giannetti, Edoardo Carsana, Nicolò Gualandi, Roberta Noberini et al. · 2026 · Nature Communications
  48. Histone-modifying Enzymes as Therapeutic Targets in Glioma
    Briana A. Santo, A. Karim Ahmed, Samuel Emerson · 2026 · Hematology/Oncology Clinics of North America
  49. The Senescent Cell Induced Bystander Effect
    James Wordsworth · 2014
  50. Networks of Histone Demethylases and Their Relevance to the Regulation of Chromatin Structure and Dynamics
    Edyta Marcon, Sandra Smiley, Andrei L. Turinsky, Jack F. Greenblatt · 2013 · Springer eBooks