The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
FGF signaling pathways in endochondral and intramembranous bone development and human genetic disease
Open accessAbstract
Over the last decade the identification of mutations in the receptors for fibroblast growth factors (FGFs) has defined essential roles for FGF signaling in both endochondral and intramembranous bone development.FGF signaling pathways are essential for the earliest stages of limb development and throughout skeletal development.In this review, we examine the role of FGF signaling in bone development and in human genetic diseases that affect bone development.We also explore what is presently known about how FGF signaling pathways interact with other major signaling pathways that regulate chondrogenesis and osteogenesis.
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Cites
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Self-citationReceptor Specificity of the Fibroblast Growth Factor Family
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Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation
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A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome
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Disruption of the fibroblast growth factor-2 gene results in decreased bone mass and bone formation
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“However, no defects in chondrogenesis were observed (Montero et al. 2000).”
BackgroundFunctional haploinsufficiency of the human homeobox gene MSX2 causes defects in skull ossification
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Cited by
Stöckl, S., Göttl, C., Grifka, J., & Grässel, S. (2013) · Cellular Physiology and Biochemistry · doi:10.1159/000350089 · Cited by 4,656
Fibroblast growth factor signalling: from development to cancer
Turner, N., & Grose, R. (2010) · Nature Reviews Cancer · doi:10.1038/nrc2780 · Cited by 2,693
Extracellular Matrix Degradation and Remodeling in Development and Disease
Lu, P., Takai, K., Weaver, V. M., & Werb, Z. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005058 · Cited by 2,265
Receptor Specificity of the Fibroblast Growth Factor Family
Zhang, X., Ibrahimi, O. A., Olsen, S. K., Umemori, H., Mohammadi, M., & Ornitz, D. M. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m601252200 · Cited by 1,164
Self-citationGenetic Control of Bone Formation
Karsenty, G., Kronenberg, H. M., & Settembre, C. (2009) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.042308.113308 · Cited by 667
Metadata
- Authors
- Ornitz, D. M., & Marie, P. J.
- Venue
- Genes & Development
- Publisher
- Cold Spring Harbor Laboratory
- Published
- 2002-06-15
- Volume
- 16
- Issue
- 12
- Pages
- 1446-1465
- ISSN
- 0890-9369 (ISSN-L)
- 1549-5477
- OpenAlex
- W2102894828
- Cited by
- 905
- References
- 9
- Type
- posted content
- Language
- en
- Open access
- diamond
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