Genetic Control of Bone Formation

Notch Signaling: Cell Fate Control and Signal Integration in Development

Artavanis-Tsakonas, S., Rand, M. D., & Lake, R. J. (1999) · Science · doi:10.1126/science.284.5415.770 · Cited by 5,909 · see citing works

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell · doi:10.1016/j.cell.2006.10.018 · Cited by 5,568 · see citing works

The Wnt Signaling Pathway in Development and Disease

Logan, C. Y., & Nusse, R. (2004) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.20.010403.113126 · Cited by 5,325 · see citing works

Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation

Ducy, P., Zhang, R., Geoffroy, V., Ridall, A. L., & Karsenty, G. (1997) · Cell · doi:10.1016/s0092-8674(00)80257-3 · Cited by 4,246 · see citing works

Targeted Disruption of Results in a Complete Lack of Bone Formation owing to Maturational Arrest of Osteoblasts

Komori, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., Shimizu, Y., Bronson, R. T., Gao, Y.-H., Inada, M., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80258-5 · Cited by 4,244 · see citing works

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

Nakashima, K., Zhou, X., Kunkel, G., Zhang, Z., Deng, J. M., Behringer, R. R., & de Crombrugghe, B. (2002) · Cell · doi:10.1016/s0092-8674(01)00622-5 · Cited by 3,608 · see citing works

An Integrated Stress Response Regulates Amino Acid Metabolism and Resistance to Oxidative Stress

Harding, H. P., Zhang, Y., Zeng, H., Novoa, I., Lu, P. D., Calfon, M. A., Sadri, N., Yun, C., Popko, B., Paules, R. S., et al. (2003) · Molecular Cell · doi:10.1016/s1097-2765(03)00105-9 · Cited by 3,336 · see citing works

Hedgehog signaling in animal development: paradigms and principlesPreprint

Ingham, P. W., & McMahon, A. P. (2001) · Genes & Development · doi:10.1101/gad.938601 · Cited by 2,987 · see citing works

AP-1 function and regulation

Karin, M., Liu, Z.-G., & Zandi, E. (1997) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(97)80068-3 · Cited by 2,904 · see citing works

Developmental regulation of the growth plate

Kronenberg, H. M. (2003) · Nature · doi:10.1038/nature01657 · Cited by 2,859 · see citing works

Endocrine regulation of energy metabolism by the skeleton

Lee, N. K., Sowa, H., Hinoi, E., Ferron, M., Ahn, J. D., Confavreux, C., Dacquin, R., Mee, P. J., McKee, M. D., Jung, D. Y., et al. (2007) · Cell · doi:10.1016/j.cell.2007.05.047 · Cited by 2,554 · see citing works

LDL Receptor-Related Protein 5 (LRP5) Affects Bone Accrual and Eye Development

Gong, Y., Slee, R. B., Fukai, N., Rawadi, G., Roman-Roman, S., Reginato, A. M., Wang, H., Cundy, T., Glorieux, F. H., Lev, D., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00571-2 · Cited by 2,235 · see citing works

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

Gerber, H. P., Vu, T. H., Ryan, A. M., Kowalski, J., Werb, Z., & Ferrara, N. (1999) · Nature Medicine · doi:10.1038/9467 · Cited by 2,089 · see citing works

Leptin Inhibits Bone Formation through a Hypothalamic Relay

Ducy, P., Amling, M., Takeda, S., Priemel, M., Schilling, A. F., Beil, F. T., Shen, J., Vinson, C., Rueger, J. M., & Karsenty, G. (2000) · Cell · doi:10.1016/s0092-8674(00)81558-5 · Cited by 2,077 · see citing works

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

Vortkamp, A., Lee, K., Lanske, B., Segre, G. V., Kronenberg, H. M., & Tabin, C. J. (1996) · Science · doi:10.1126/science.273.5275.613 · Cited by 1,999 · see citing works

Receptor Specificity of the Fibroblast Growth Factor Family

Ornitz, D. M., Xu, J., Colvin, J. S., McEwen, D. G., MacArthur, C. A., Coulier, F., Gao, G., & Goldfarb, M. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.25.15292 · Cited by 1,871 · see citing works

WNT and β-catenin signalling: diseases and therapies

Moon, R. T., Kohn, A. D., Ferrari, G. V. D., & Kaykas, A. (2004) · Nature Reviews Genetics · doi:10.1038/nrg1427 · Cited by 1,763 · see citing works

Sox9 is required for cartilage formation

Bi, W., Deng, J. M., Zhang, Z., Behringer, R. R., & Crombrugghe, B. D. (1999) · Nature Genetics · doi:10.1038/8792 · Cited by 1,760 · see citing works

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formationPreprint

St‐Jacques, B., Hammerschmidt, M., & McMahon, A. P. (1999) · Genes & Development · doi:10.1101/gad.13.16.2072 · Cited by 1,742 · see citing works

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

Vu, T. H., Shipley, J. M., Bergers, G., Berger, J. E., Helms, J. A., Hanahan, D., Shapiro, S. D., Senior, R. M., & Werb, Z. (1998) · Cell · doi:10.1016/s0092-8674(00)81169-1 · Cited by 1,737 · see citing works

Leptin Regulates Bone Formation via the Sympathetic Nervous System

Takeda, S., Elefteriou, F., Levasseur, R., Liu, X., Zhao, L., Parker, K. L., Armstrong, D., Ducy, P., & Karsenty, G. (2002) · Cell · doi:10.1016/s0092-8674(02)01049-8 · Cited by 1,735 · see citing works

The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of <i>Sox5</i> and <i>Sox6</i>

Akiyama, H., Chaboissier, M.-C., Martin, J. F., Schedl, A., & de Crombrugghe, B. (2002) · Genes &amp; Development · doi:10.1101/gad.1017802 · Cited by 1,721 · see citing works

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

Schroeter, E. H., Kisslinger, J. A., & Kopan, R. (1998) · Nature · doi:10.1038/30756 · Cited by 1,624 · see citing works

Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis

Day, T. F., Guo, X., Garrett-Beal, L., & Yang, Y. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.03.016 · Cited by 1,616 · see citing works

Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

Foster, J. W., Dominguez-Steglich, M., Guioli, S., Kwok, C., Weller, P., Stevanović, M., Weissenbach, J., Mansour, S., Young, I., Goodfellow, P., et al. (1994) · Nature · doi:10.1038/372525a0 · Cited by 1,602 · see citing works

Reaching a Genetic and Molecular Understanding of Skeletal Development

Karsenty, G., & Wagner, E. F. (2002) · Developmental Cell · doi:10.1016/s1534-5807(02)00157-0 · Cited by 1,594 · see citing works

Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9.

Wagner, T., Wirth, J., Meyer, J., Zabel, B., Held, M., Zimmer, J., Pasantes, J., Bricarelli, F. D., Keutel, J., Hustert, E., et al. (1994) · Cell · doi:10.1016/0092-8674(94)90041-8 · Cited by 1,592 · see citing works

High Bone Density Due to a Mutation in LDL-Receptor–Related Protein 5

Boyden, L. M., Mao, J., Belsky, J., Mitzner, L., Farhi, A., Mitnick, M. A., Wu, D., Insogna, K., & Lifton, R. P. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013444 · Cited by 1,591 · see citing works

The serotonin signaling system: from basic understanding to drug development for functional GI disorders

Gershon, M. D., & Tack, J. (2007) · Gastroenterology · doi:10.1053/j.gastro.2006.11.002 · Cited by 1,563 · see citing works

Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation.

Glass, D. A., Bialek, P., Ahn, J. D., Starbuck, M., Patel, M. S., Clevers, H., Taketo, M. M., Long, F., McMahon, A. P., Lang, R. A., et al. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.02.017 · Cited by 1,558 · see citing works

A new member of the frizzled family from Drosophila functions as a Wingless receptor

Bhanot, P., van den Brink, M. R. M., Samos, C. H., Hsieh, J.-C., Wang, Y., Macke, J. P., Andrew, D. J., Nathans, J., & Nusse, R. (1996) · Nature · doi:10.1038/382225a0 · Cited by 1,504 · see citing works

Mutations Involving the Transcription Factor CBFA1 Cause Cleidocranial Dysplasia

Mundlos, S., Otto, F., Mundlos, C., Mulliken, J. B., Aylsworth, A. S., Albright, S. G., Lindhout, D., Cole, W. G., Henn, W., Knoll, J. H. M., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80260-3 · Cited by 1,502 · see citing works

PTH/PTHrP Receptor in Early Development and Indian Hedgehog—Regulated Bone Growth

Lanske, B., Karaplis, A. C., Lee, K., Luz, A., Vortkamp, A., Pirro, A. E., Karperien, M., Defize, L. H. K., Ho, C., Mulligan, R. C., et al. (1996) · Science · doi:10.1126/science.273.5275.663 · Cited by 1,325 · see citing works

Leptin regulation of bone resorption by the sympathetic nervous system and CART

Elefteriou, F., Ahn, J. D., Takeda, S., Starbuck, M., Yang, X., Liu, X., Kondo, H., Richards, W. G., Bannon, T. W., Noda, M., et al. (2005) · Nature · doi:10.1038/nature03398 · Cited by 1,311 · see citing works

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia.

Shiang, R., Thompson, L., Zhu, Y.-Z., Church, D., Fielder, T., Bocian, M., Winokur, S., & Wasmuth, J. (1994) · Cell · doi:10.1016/0092-8674(94)90302-6 · Cited by 1,291 · see citing works

Structural and functional diversity in the FGF receptor multigene family.

Johnson, D. E., & Williams, L. (1993) · Advances in Cancer Research · doi:10.1016/s0065-230x(08)60821-0 · Cited by 1,270 · see citing works

A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva

Shore, E. M., Xu, M., Feldman, G. J., Fenstermacher, D., Cho, T., Choi, I. H., Connor, J. M., Delai, P. L. R., Glaser, D. L., Merrer, M. F. L., et al. (2006) · Nature Genetics · doi:10.1038/ng1783 · Cited by 1,215 · see citing works

Lethal skeletal dysplasia from targeted disruption of the parathyroid hormone-related peptide gene.Preprint

Karaplis, A. C., Luz, A., Glowacki, J., Bronson, R. T., Tybulewicz, V. L. J., Kronenberg, H. M., & Mulligan, R. C. (1994) · Genes & Development · doi:10.1101/gad.8.3.277 · Cited by 1,151 · see citing works

Fibroblast growth factor receptor 3 is a negative regulator of bone growth.

Deng, C.-X., Wynshaw-Boris, A., Zhou, F., Kuo, A., & Leder, P. (1996) · Cell · doi:10.1016/s0092-8674(00)81069-7 · Cited by 1,095 · see citing works

Canonical Wnt/β-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes

Hill, T. P., Später, D., Taketo, M. M., Birchmeier, W., & Hartmann, C. (2005) · Developmental Cell · doi:10.1016/j.devcel.2005.02.013 · Cited by 1,086 · see citing works

SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene

Lefebvre, V., Huang, W., Harley, V. R., Goodfellow, P. N., & Crombrugghe, B. D. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.4.2336 · Cited by 1,077 · see citing works

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

Rousseau, F., Bonaventure, J., Legeai-Mallet, L., Pelet, A., Rozet, J., Maroteaux, P., Merrer, M. L., & Munnich, A. (1994) · Nature · doi:10.1038/371252a0 · Cited by 920 · see citing works

FGF signaling pathways in endochondral and intramembranous bone development and human genetic diseasePreprint

Ornitz, D. M., & Marie, P. J. (2002) · Genes & Development · doi:10.1101/gad.990702 · Cited by 902 · see citing works

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3

Colvin, J. S., Bohne, B. A., Harding, G. W., McEwen, D. G., & Ornitz, D. M. (1996) · Nature Genetics · doi:10.1038/ng0496-390 · Cited by 868 · see citing works

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

Yadav, V. K., Ryu, J.-H., Suda, N., Tanaka, K. F., Gingrich, J. A., Schütz, G., Glorieux, F. H., Chiang, C. Y., Zajac, J. D., Insogna, K. L., et al. (2008) · Cell · doi:10.1016/j.cell.2008.09.059 · Cited by 837 · see citing works

ATF4 Is a Substrate of RSK2 and an Essential Regulator of Osteoblast Biology

Yang, X., Matsuda, K., Bialek, P., Jacquot, S., Masuoka, H. C., Schinke, T., Li, L., Brancorsini, S., Sassone‐Corsi, P., Townes, T. M., et al. (2004) · Cell · doi:10.1016/s0092-8674(04)00344-7 · Cited by 822 · see citing works

Hypoxia in cartilage: HIF-1α is essential for chondrocyte growth arrest and survivalPreprint

Schipani, E., Ryan, H. E., Didrickson, S., Kobayashi, T., Knight, M. C., & Johnson, R. S. (2001) · Genes & Development · doi:10.1101/gad.934301 · Cited by 812 · see citing works

A new long form of Sox5 (L‐Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene

Lefebvre, V., Li, P., & de Crombrugghe, B. (1998) · The EMBO Journal · doi:10.1093/emboj/17.19.5718 · Cited by 811 · see citing works

Histone Deacetylase 4 Controls Chondrocyte Hypertrophy during Skeletogenesis

Vega, R. B., Matsuda, K., Oh, J., Barbosa, A. C. C., Yang, X., Meadows, E., McAnally, J., Pomajzl, C., Shelton, J. M., Richardson, J. A., et al. (2004) · Cell · doi:10.1016/j.cell.2004.10.024 · Cited by 805 · see citing works

Interactions between Sox9 and β-catenin control chondrocyte differentiationPreprint

Akiyama, H., Lyons, J. P., Mori–Akiyama, Y., Yang, X., Zhang, R., Zhang, Z., Deng, J. M., Taketo, M. M., Nakamura, T., Behringer, R. R., et al. (2004) · Genes & Development · doi:10.1101/gad.1171104 · Cited by 755 · see citing works

Msx2 deficiency in mice causes pleiotropic defects in bone growth and ectodermal organ formation

Satokata, I., Ma, L., Ohshima, H., Bei, M., Woo, I., Nishizawa, K., Maeda, T., Takano, Y., Uchiyama, M., Heaney, S., et al. (2000) · Nature Genetics · doi:10.1038/74231 · Cited by 737 · see citing works

A Constitutively Active Mutant PTH-PTHrP Receptor in Jansen-Type Metaphyseal Chondrodysplasia

Schipani, E., Kruse, K., & Jüppner, H. (1995) · Science · doi:10.1126/science.7701349 · Cited by 675 · see citing works

A Twist Code Determines the Onset of Osteoblast Differentiation

Bialek, P., Kern, B., Yang, X., Schrock, M., Šošić, D., Hong, N. A., Wu, H., Yu, K., Ornitz, D. M., Olson, E. N., et al. (2004) · Developmental Cell · doi:10.1016/s1534-5807(04)00058-9 · Cited by 674 · see citing works

Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation

Long, F., Zhang, X. M., Karp, S. J., Yang, Y., & McMahon, A. P. (2001) · Development · doi:10.1242/dev.128.24.5099 · Cited by 654 · see citing works

Mutations in TWIST, a basic helix–loop–helix transcription factor, in Saethre-Chotzen syndrome

Howard, T. D., Paznekas, W. A., Green, E. D., Chiang, L. C., Ma, N. S. F., Luna, R. I. O. D., Delgado, C. G., Gonzalez-Ramos, M., Kline, A. D., & Jabs, E. W. (1997) · Nature Genetics · doi:10.1038/ng0197-36 · Cited by 645 · see citing works

Mutations of the TWIST gene in the Saethre-Chotzene syndrome

Ghouzzi, V. E., Merrer, M. F. L., Perrin‐Schmitt, F., Lajeunie, E., Bénit, P., Rénier, D., Bourgeois, P., Bolcato‐Bellemin, A., Münnich, A., & Bonaventure, J. (1997) · Nature Genetics · doi:10.1038/ng0197-42 · Cited by 639 · see citing works

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

Hilton, M. J., Tu, X., Wu, X., Bai, S., Zhao, H., Kobayashi, T., Kronenberg, H. M., Teitelbaum, S. L., Ross, F. P., Kopan, R., et al. (2008) · Nature Medicine · doi:10.1038/nm1716 · Cited by 604 · see citing works

The Transcription Factors L-Sox5 and Sox6 Are Essential for Cartilage Formation

Smits, P. J., Li, P., Mandel, J., Zhang, Z., Deng, J. M., Behringer, R. R., Crombrugghe, B. D., & Lefèbvre, V. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00003-x · Cited by 600 · see citing works

Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3

Tavormina, P. L., Shiang, R., Thompson, L., Zhu, Y.-Z., Wilkin, D. J., Lachman, R., Wilcox, W., Rimoin, D., Cohn, D., & Wasmuth, J. (1995) · Nature Genetics · doi:10.1038/ng0395-321 · Cited by 591 · see citing works

Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehogPreprint

Yoshida, C. A., Yamamoto, H., Fujita, T., Furuichi, T., Ito, K., Inoue, K., Yamana, K., Zanma, A., Takada, K., Ito, Y., et al. (2004) · Genes & Development · doi:10.1101/gad.1174704 · Cited by 588 · see citing works

Bone and Mineral Research/4

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The Molecular Clock Mediates Leptin-Regulated Bone Formation

Fu, L., Patel, M. S., Bradley, A., Wagner, E. F., & Karsenty, G. (2005) · Cell · doi:10.1016/j.cell.2005.06.028 · Cited by 575 · see citing works

Missense mutations abolishing DNA binding of the osteoblast-specific transcription factor OSF2/CBFA1 in cleidocranial dysplasia

Lee, B., Thirunavukkarasu, K., Zhou, L., Pastore, L., Baldini, A., Hecht, J. T., Geoffrey, V., Ducy, P. F., & Karsenty, G. (1997) · Nature Genetics · doi:10.1038/ng0797-307 · Cited by 567 · see citing works

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

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Fos/AP‐1 proteins in bone and the immune system

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Graded activation of fibroblast growth factor receptor 3 by mutations causing achondroplasia and thanatophoric dysplasia

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SATB2 Is a Multifunctional Determinant of Craniofacial Patterning and Osteoblast Differentiation

Dobreva, G. D., Chahrour, M. H., Dautzenberg, M., Chirivella, L., Kanzler, B., Fariñas, I., Karsenty, G., & Grosschedl, R. (2006) · Cell · doi:10.1016/j.cell.2006.05.012 · Cited by 522 · see citing works

Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient micePreprint

Takeda, S., Bonnamy, J.-P., Owen, M. J., Ducy, P. F., & Karsenty, G. (2001) · Genes & Development · doi:10.1101/gad.845101 · Cited by 518 · see citing works

Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18.Preprint

Liu, Z.-H., Xu, J.-S., Colvin, J. S., & Ornitz, D. (2002) · Genes & Development · doi:10.1101/gad.965602 · Cited by 501 · see citing works

NFAT and Osterix cooperatively regulate bone formation

Koga, T., Matsui, Y., Asagiri, M., Kodama, T., Crombrugghe, B. D., Nakashima, K., & Takayanagi, H. (2005) · Nature Medicine · doi:10.1038/nm1270 · Cited by 490 · see citing works

FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis.Preprint

Ohbayashi, N., Shibayama, M., Kurotaki, Y., Imanishi, M., Fujimori, T., Itoh, N., & Takada, S. (2002) · Genes & Development · doi:10.1101/gad.965702 · Cited by 487 · see citing works

Dual roles of Wnt signaling during chondrogenesis in the chicken limb

Hartmann, C., & Tabin, C. J. (2000) · Development · doi:10.1242/dev.127.14.3141 · Cited by 472 · see citing works

MEF2C Transcription Factor Controls Chondrocyte Hypertrophy and Bone Development

Arnold, M., Kim, Y., Czubryt, M. P., Phan, D., McAnally, J., Qi, X., Shelton, J. M., Richardson, J. A., Bassel‐Duby, R., & Olson, E. N. (2007) · Developmental Cell · doi:10.1016/j.devcel.2007.02.004 · Cited by 456 · see citing works

Bone morphogenetic protein-3 is a negative regulator of bone density

Daluiski, A., Engstrand, T., Bahamonde, M. E., Gamer, L. W., Agius, E., Stevenson, S., Cox, K. A., Rosen, V., & Lyons, K. M. (2001) · Nature Genetics · doi:10.1038/83810 · Cited by 427 · see citing works

Convergence between bone and energy homeostases: Leptin regulation of bone mass

Karsenty, G. (2006) · Cell Metabolism · doi:10.1016/j.cmet.2006.10.008 · Cited by 415 · see citing works

Dimorphic effects of Notch signaling in bone homeostasis

Engin, F., Yao, Z., Yang, T., Zhou, G. D., Bertin, T., Jiang, M. M., Chen, Y., Wang, L. E., Zheng, H., Sutton, R. E., et al. (2008) · Nature Medicine · doi:10.1038/nm1712 · Cited by 413 · see citing works

Patterning Mechanisms Controlling Vertebrate Limb Development

Capdevila, J., & Belmonte, J. C. I. (2001) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.17.1.87 · Cited by 399 · see citing works

Wnt5aandWnt5bexhibit distinct activities in coordinating chondrocyte proliferation and differentiation

Yang, Y., Topol, L. Z., Lee, H., & Wu, J. (2003) · Development · doi:10.1242/dev.00324 · Cited by 398 · see citing works

FGF signaling inhibits chondrocyte proliferation and regulates bone development through the STAT-1 pathway.Preprint

Sahni, M., Ambrosetti, D., Mansukhani, A., Gertner, R., Levy, D., & Basilico, C. (1999) · Genes & Development · doi:10.1101/gad.13.11.1361 · Cited by 391 · see citing works

Up-regulation of the chondrogenic Sox9 gene by fibroblast growth factors is mediated by the mitogen-activated protein kinase pathway

Murakami, S., Kan, M., McKeehan, W. L., & Crombrugghe, B. D. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.97.3.1113 · Cited by 377 · see citing works

Overexpression of ΔFosB transcription factor(s) increases bone formation and inhibits adipogenesis

Sabatakos, G., Sims, N. A., Chen, J., Aoki, K., Kelz, M. B., Amling, M., Bouali, Y., Mukhopadhyay, K., Ford, K.-K., Nestler, E. J., et al. (2000) · Nature Medicine · doi:10.1038/79683 · Cited by 337 · see citing works

Activation of Statl by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism

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Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1

Jochum, W., David, J., Elliott, C., Wutz, A., Plenk, H., Jr., Matsuo, K., & Wagner, E. F. (2000) · Nature Medicine · doi:10.1038/79676 · Cited by 310 · see citing works

BMPs Are Required at Two Steps of Limb Chondrogenesis: Formation of Prechondrogenic Condensations and Their Differentiation into Chondrocytes

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Core-binding factor β interacts with Runx2 and is required for skeletal development

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