Cited by 420Light effects on plantsSkin Protection and AgingPlant Gene Expression Analysis

Flavonoids Can Protect Maize DNA from the Induction of Ultraviolet Radiation Damage

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Stapleton, A. E., Walbot, V.·1994·Plant Physiology

Abstract

Diverse flavonoid compounds are widely distributed in angiosperm families. Flavonoids absorb radiation in the ultraviolet (UV) region of the spectrum, and it has been proposed that these compounds function as UV filters. We demonstrate that the DNA in Zea mays plants that contain flavonoids (primarily anthocyanins) is protected from the induction of damage caused by UV radiation relative to the DNA in plants that are genetically deficient in these compounds. DNA damage was measured with a sensitive and simple assay using individual monoclonal antibodies, one specific for cyclobutane pyrimidine dimer damage and the other specific for pyrimidine(6,4)pyrimidone damage.

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Crossref · 10.1104/pp.105.3.881

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  • Plants have acquired two main protective strategies against UVR: shielding by flavonoids and phenolic compounds, and DNA repair by photoreactivation.

    “To avoid the deleterious effects of UVR, plants have acquired two main protective strategies; shielding by flavonoids and phenolic compounds [168, 169] and DNA repair by photoreactivation.”

    From Molecular Mechanisms of Ultraviolet Radiation‐Induced DNA Damage and Repair (2010) · cites this paper as [168]

    The paper’s Results (page not supplied) show that flavonoid-containing maize tissue had less UV-induced DNA damage, supporting flavonoid shielding. Our copy does not establish shielding by phenolic compounds beyond flavonoids. The citation is attached to the shielding clause, not the subsequent photoreactivation clause. (LLM, conf=0.84)

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Research works printed but not linked: 1

  1. Rivin CJ, Zimmer EA, Walbot V (1982) Isolation of DNA. and DNA recombinants from maize. In WF Sheridan, ed, Maize fo;: Biological 445-450 5 0 451-457 1985-1992 47-78 17-29 Downloaded from https://academic.oup.com/plphys/article/105/3/881/6068122 by guest on 22 October 2023

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Authors
Stapleton, A. E., & Walbot, V.
Affiliations
Stanford University (US)
Venue
Plant Physiology
Published
1994-07-01
Volume
105
Issue
3
Pages
881-889
ISSN
  • 0032-0889 (ISSN-L)
  • 1532-2548
OpenAlex
W2120833079
Cited by
420
References
41
Citations by year
2026: 1 · 2025: 13 · 2024: 8 · 2023: 8 · 2022: 11 · 2021: 11 · 2020: 9 · 2019: 10 · 2018: 9 · 2017: 14 · 2016: 14 · 2015: 15 · 2014: 9 · 2013: 10 · 2012: 18
FWCI
16.84
Type
journal article
Language
en
Open access
Locations
  • PLANT PHYSIOLOGY (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Institutes of Health (1f32es005545-01)
  • National Institute of Environmental Health Sciences (F32 ES05545)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Light effects on plants
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant Gene Expression Analysis
Keywords
flavonoids, anthocyanins, maize, ultraviolet radiation, DNA damage, UV protection, cyclobutane pyrimidine dimers, monoclonal antibodies, UV filters
MeSH terms
Anthocyanins, Zea mays, DNA, DNA Damage, Dose-Response Relationship, Radiation, Flavonoids, Kinetics, Ultraviolet Rays

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