A Novel N-Methyltransferase in Arabidopsis Appears to Feed a Conserved Pathway for Nicotinate Detoxification among Land Plants and Is Associated with Lignin Biosynthesis
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MT and COMT might have facilitated the retention of the Preiss-Handler pathway in land plants.
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Its synthesis from NA via methylation confers protective and adaptive functions, without an established reutilization as a Preiss-Handler substrate.
“Its synthesis from NA via methylation confers protective and adaptive functions4,48, without an established reutilization as a Preiss–Handler substrate49,50.”
From Trigonelline Is an NAD+ Precursor That Improves Muscle Function during Ageing and Is Reduced in Human Sarcopenia (2024) · cites this paper as [49]
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Self-citation
- Authors
- Li, W., Zhang, F., Wu, R., Jia, L., Li, G., Guo, Y., Liu, C., & Wang, G.
- Affiliations
- Chinese Academy of Sciences (CN)
- State Key Laboratory of Plant Genomics and National Center for Plant Gene Research, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China
- State Key Laboratory of Systematic and Evolutionary Botany, Institute of Botany, Chinese Academy of Sciences, Beijing 100093, China
- Venue
- Plant Physiology
- Publisher
- Oxford University Press (OUP)
- Published
- 2017-05-22
- Volume
- 174
- Issue
- 3
- Pages
- 1492-1504
- ISSN
- 0032-0889 (ISSN-L)
- 1532-2548
- PMC
- PMC5490898
- OpenAlex
- W2618568624
- Cited by
- 34
- References
- 47
- Citations by year
- 2026: 4 · 2025: 6 · 2024: 3 · 2023: 3 · 2022: 5 · 2021: 4 · 2020: 3 · 2019: 3 · 2018: 3
- FWCI
- 1.01
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- cc-by
- Locations
- PLANT PHYSIOLOGY (publishedVersion, cc-by)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Institute of Botany, CAS Institutional Repository (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant Gene Expression Analysis
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Plant Molecular Biology Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Plant biochemistry and biosynthesis
- Keywords
- N-methyltransferase, Preiss-Handler pathway, lignin biosynthesis, catechol-O-methyltransferase, Arabidopsis thaliana, land plants, nicotinate metabolism
- MeSH terms
- Alkaloids, Lignin, Inactivation, Metabolic, NAD, Niacin, Phylogeny, Subcellular Fractions, Arabidopsis, Plant Roots, Arabidopsis Proteins, Structural Homology, Protein, Biocatalysis
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