The DOI matches its Crossref record; 46 of the 46 references it cites were found in a registry or an index.
The Arabidopsis Photomorphogenic Mutant hy1 Is Deficient in Phytochrome Chromophore Biosynthesis as a Result of a Mutation in a Plastid Heme Oxygenase
Open accessAbstract
The HY1 locus of Arabidopsis is necessary for phytochrome chromophore biosynthesis and is defined by mutants that show a long hypocotyl phenotype when grown in the light. We describe here the molecular cloning of the HY1 gene by using chromosome walking and mutant complementation. The product of the HY1 gene shows significant similarity to animal heme oxygenases and contains a possible transit peptide for transport to plastids. Heme oxygenase activity was detected in the HY1 protein expressed in Escherichia coli. Heme oxygenase catalyzes the oxygenation of heme to biliverdin, an activity that is necessary for phytochrome chromophore biosynthesis. The predicted transit peptide is sufficient to transport the green fluorescent protein into chloroplasts. The accumulation of the HY1 protein in plastids was detected by using immunoblot analysis with an anti-HY1 antiserum. These results indicate that the Arabidopsis HY1 gene encodes a plastid heme oxygenase necessary for phytochrome chromophore biosynthesis.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
A Revised Medium for Rapid Growth and Bio Assays with Tobacco Tissue Cultures
Murashige, T., & Skoog, F. (1962) · Physiologia Plantarum · doi:10.1111/j.1399-3054.1962.tb08052.x · Cited by 67,392
Antibodies, a laboratory manual
(1989) · Biomedicine & Pharmacotherapy · doi:10.1016/0753-3322(89)90130-3 · Cited by 12,366
Church, G. M., & Gilbert, W. (1984) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.81.7.1991 · Cited by 8,116
Binary Agrobacterium vectors for plant transformation
Bevan, M. (1984) · Nucleic Acids Research · doi:10.1093/nar/12.22.8711 · Cited by 2,166
Genetic applications of an inverse polymerase chain reaction.
Ochman, H., Gerber, A. S., & Hartl, D. L. (1988) · Genetics · doi:10.1093/genetics/120.3.621 · Cited by 1,859
A procedure for mapping Arabidopsis mutations using co‐dominant ecotype‐specific PCR‐based markers
Konieczny, A., & Ausubel, F. M. (1993) · The Plant Journal · doi:10.1046/j.1365-313x.1993.04020403.x · Cited by 1,570
Engineered GFP as a vital reporter in plants
Chiu, W.-L., Niwa, Y., Zeng, W., Hirano, T., Kobayashi, H., & Sheen, J. (1996) · Current Biology · doi:10.1016/s0960-9822(02)00483-9 · Cited by 1,364
Valvekens, D., Montagu, M. V., & Lijsebettens, M. V. (1988) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.85.15.5536 · Cited by 1,277
Domain structure of mitochondrial and chloroplast targeting peptides
von HEIJNE, G., STEPPUHN, J., & HERRMANN, R. G. (1989) · European Journal of Biochemistry · doi:10.1111/j.1432-1033.1989.tb14679.x · Cited by 1,187
Sharrock, R. A., & Quail, P. H. (1989) · Genes & Development · doi:10.1101/gad.3.11.1745 · Cited by 838
Cited by
Loboda, A., Damulewicz, M., Pyza, E., Jozkowicz, A., & Dulak, J. (2016) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2223-0 · Cited by 2,632
Heme oxygenase: colors of defense against cellular stress
Otterbein, L. E., & Choi, A. M. K. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.6.l1029 · Cited by 870
Phytochrome Signaling Mechanisms
Li, J., Li, G., Wang, H., & Wang Deng, X. (2011) · The Arabidopsis Book · doi:10.1199/tab.0148 · Cited by 561
The Mg-chelatase H subunit is an abscisic acid receptor
Shen, Y.-Y., Wang, X.-F., Wu, F.-Q., Du, S.-Y., Cao, Z., Shang, Y., Wang, X.-L., Peng, C.-C., Yu, X.-C., Zhu, S.-Y., et al. (2006) · Nature · doi:10.1038/nature05176 · Cited by 538
Origins and estimates of uncertainty in predictions of twenty-first century temperature rise
Stott, P. A., & Kettleborough, J. A. (2002) · Nature · doi:10.1038/416723a · Cited by 373
Metadata
- Authors
- Muramoto, T., Kohchi, T., Yokota, A., Hwang, I., & Goodman, H. M.
- Venue
- The Plant Cell
- Publisher
- Oxford University Press (OUP)
- Published
- 1999-03
- Volume
- 11
- Issue
- 3
- Pages
- 335-347
- ISSN
- 1040-4651 (ISSN-L)
- 1532-298X
- OpenAlex
- W2130471243
- Cited by
- 323
- References
- 46
- FWCI
- 26.24
- Type
- journal article
- Language
- en
- Open access
- green
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: The Arabidopsis Photomorphogenic Mutant hy1 Is Deficient in Phytochrome Chromophore Biosynthesis as a Result of a Mutation in a Plastid Heme Oxygenase. https://app.cochat.ai/papers/10.1105/tpc.11.3.335
- The paper
- Muramoto, T., Kohchi, T., Yokota, A., Hwang, I., & Goodman, H. M. (1999). The Arabidopsis Photomorphogenic Mutant hy1 Is Deficient in Phytochrome Chromophore Biosynthesis as a Result of a Mutation in a Plastid Heme Oxygenase. The Plant Cell. https://doi.org/10.1105/tpc.11.3.335
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
