Skin lesion analysis toward melanoma detection: A challenge at the 2017 International symposium on biomedical imaging (ISBI), hosted by the international skin imaging collaboration (ISIC)
Open accessAbstract
This article describes the design, implementation, and results of the latest installment of the dermoscopic image analysis benchmark challenge. The goal is to support research and development of algorithms for automated diagnosis of melanoma, the most lethal skin cancer. The challenge was divided into 3 tasks: lesion segmentation, feature detection, and disease classification. Participation involved 593 registrations, 81 pre-submissions, 46 finalized submissions (including a 4-page manuscript), and approximately 50 attendees, making this the largest standardized and comparative study in this field to date. While the official challenge duration and ranking of participants has concluded, the dataset snapshots remain available for further research and development.
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Neural networks can leverage additional data by integrating multiple modalities into a general framework.
“Previous works demonstrate the ability of neural networks to leverage additional data by integrating multiple modalities into a general framework.[11,27,28]”
From Multimodal skin lesion classification using deep learning (2018) · cites this paper as [11]
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Cites
Siegel, R. L., Miller, K. D., & Jemal, A. (2016) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21332 · Cited by 16,003 · see citing works
Siegel, R. L., Miller, K. D., & Jemal, A. (2017) · CA: A Cancer Journal for Clinicians · doi:10.3322/caac.21387 · Cited by 14,712 · see citing works
PH<sup>2</sup> - A dermoscopic image database for research and benchmarking
Mendonca, T., Ferreira, P. M., Marques, J. S., Marcal, A. R. S., & Rozeira, J. (2013) · 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2013.6610779 · Cited by 1,009 · see citing works
The US dermatology workforce: a specialty remains in shortage.
Kimball, A. B., & Resneck, J. S. (2008) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2008.06.037 · Cited by 257 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Tschandl, P., Rosendahl, C., & Kittler, H. (2018) · Scientific Data · doi:10.1038/sdata.2018.161 · Cited by 3,628 · see citing works
Self-citationThe Liver Tumor Segmentation Benchmark (LiTS)
Bilic, P., Christ, P., Li, H. B., Vorontsov, E., Ben-Cohen, A., Kaissis, G., Szeskin, A., Jacobs, C., Mamani, G. E. H., Chartrand, G., et al. (2023) · Medical Image Analysis · doi:10.1016/j.media.2022.102680 · Cited by 1,412 · see citing works
Automated Melanoma Recognition in Dermoscopy Images via Very Deep Residual Networks
Yu, L., Chen, H., Dou, Q., Qin, J., & Heng, P.-A. (2017) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2016.2642839 · Cited by 1,140 · see citing works
Machine Learning Methods for Histopathological Image Analysis
Komura, D., & Ishikawa, S. (2018) · Computational and Structural Biotechnology Journal · doi:10.1016/j.csbj.2018.01.001 · Cited by 937 · see citing works
Automatic skin lesion segmentation using deep fully convolutional networks with jaccard distance.
Yuan, Y., Chao, M., & Lo, Y.-C. (2017) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2017.2695227 · Cited by 687 · see citing works
Towards a guideline for evaluation metrics in medical image segmentation
Müller, D., Soto-Rey, I., & Kramer, F. (2022) · BMC Research Notes · doi:10.1186/s13104-022-06096-y · Cited by 668 · see citing works
Brinker, T. J., Hekler, A., Enk, A. H., Klode, J., Hauschild, A., Berking, C., Schilling, B., Haferkamp, S., Schadendorf, D., Holland-Letz, T., et al. (2019) · European Journal of Cancer · doi:10.1016/j.ejca.2019.04.001 · Cited by 605 · see citing works
Skin cancer detection: A review using deep learning techniques
Dildar, M., Akram, S., Irfan, M., Khan, H. U., Ramzan, M., Mahmood, A. R., Alsaiari, S. A., Saeed, A. H. M., Alraddadi, M. O., & Mahnashi, M. H. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18105479 · Cited by 597 · see citing works
Seven-point checklist and skin lesion classification using multitask multimodal neural nets
Kawahara, J., Daneshvar, S., Argenziano, G., & Hamarneh, G. (2019) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2018.2824327 · Cited by 584 · see citing works
Tschandl, P., Codella, N., Akay, B. N., Argenziano, G., Braun, R. P., Cabo, H., Gutman, D., Halpern, A., Helba, B., Hofmann-Wellenhof, R., et al. (2019) · The Lancet Oncology · doi:10.1016/s1470-2045(19)30333-x · Cited by 555 · see citing works
Self-citationSegment anything model for medical images?
Huang, Y., Yang, X., Liu, L., Zhou, H., Chang, A., Zhou, X., Chen, R., Yu, J., Chen, J., Chen, C., et al. (2024) · Medical Image Analysis · doi:10.1016/j.media.2023.103061 · Cited by 536 · see citing works
Multimodal skin lesion classification using deep learning
Yap, J., Yolland, W., & Tschandl, P. (2018) · Experimental Dermatology · doi:10.1111/exd.13777 · Cited by 326 · see citing works
Analysis of the ISIC image datasets: Usage, benchmarks and recommendations
Cassidy, B., Kendrick, C., Brodzicki, A., Jaworek-Korjakowska, J., & Yap, M. H. (2022) · Medical Image Analysis · doi:10.1016/j.media.2021.102305 · Cited by 307 · see citing works
Artificial Intelligence in Dermatology: A Primer
Young, A. T., Xiong, M., Pfau, J., Keiser, M. J., & Wei, M. L. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.02.026 · Cited by 249 · see citing works
Han, S. S., Park, I., Eun Chang, S., Lim, W., Kim, M. S., Park, G. H., Chae, J. B., Huh, C. H., & Na, J.-I. (2020) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2020.01.019 · Cited by 248 · see citing works
Naeem, A., Farooq, M. S., Khelifi, A., & Abid, A. (2020) · IEEE Access · doi:10.1109/access.2020.3001507 · Cited by 189 · see citing works
Structure Boundary Preserving Segmentation for Medical Image With Ambiguous Boundary
Lee, H. J., Kim, J. U., Lee, S., Kim, H. G., & Ro, Y. M. (2020) · 2020 IEEE/CVF Conference on Computer Vision and Pattern Recognition (CVPR) · doi:10.1109/cvpr42600.2020.00487 · Cited by 180 · see citing works
Skin disease diagnosis with deep learning: a review
Li, H., Pan, Y., Zhao, J., & Zhang, L. (2021) · Neurocomputing · doi:10.1016/j.neucom.2021.08.096 · Cited by 178 · see citing works
Deep Learning-Based Transfer Learning for Classification of Skin Cancer
Jain, S., Singhania, U., Tripathy, B., Nasr, E. A., Aboudaif, M. K., & Kamrani, A. K. (2021) · Sensors · doi:10.3390/s21238142 · Cited by 169 · see citing works
Operationalising ethics in artificial intelligence for healthcare: a framework for AI developers
Solanki, P., Grundy, J., & Hussain, W. (2023) · AI and Ethics · doi:10.1007/s43681-022-00195-z · Cited by 157 · see citing works
Brinker, T. J., Hekler, A., Hauschild, A., Berking, C., Schilling, B., Enk, A. H., Haferkamp, S., Karoglan, A., von Kalle, C., Weichenthal, M., et al. (2019) · European Journal of Cancer · doi:10.1016/j.ejca.2018.12.016 · Cited by 157 · see citing works
Assessing Reliability and Challenges of Uncertainty Estimations for Medical Image Segmentation
Jungo, A., & Reyes, M. (2019) · Lecture Notes in Computer Science · doi:10.1007/978-3-030-32245-8_6 · Cited by 156 · see citing works
FusionM4Net: a multi-stage multi-modal learning algorithm for multi-label skin lesion classification
Tang, P., Yan, X., Nan, Y., Xiang, S., Krammer, S., & Lasser, T. (2022) · Medical Image Analysis · doi:10.1016/j.media.2021.102307 · Cited by 131 · see citing works
Federated learning for healthcare applications
Chaddad, A., Wu, Y., & Desrosiers, C. (2024) · IEEE Internet of Things Journal · doi:10.1109/jiot.2023.3325822 · Cited by 136 · see citing works
Transparent medical image AI via an image–text foundation model grounded in medical literature
Kim, C., Gadgil, S. U., DeGrave, A. J., Omiye, J. A., Cai, Z. R., Daneshjou, R., & Lee, S.-I. (2024) · Nature Medicine · doi:10.1038/s41591-024-02887-x · Cited by 125 · see citing works
Reviewing Federated Machine Learning and Its Use in Diseases Prediction
Moshawrab, M., Adda, M., Bouzouane, A., Ibrahim, H., & Raad, A. (2023) · Sensors · doi:10.3390/s23042112 · Cited by 114 · see citing works
Pham, T.-C., Luong, C.-M., Hoang, V.-D., & Doucet, A. (2021) · Scientific Reports · doi:10.1038/s41598-021-96707-8 · Cited by 101 · see citing works
A Multimodal Vision Foundation Model for Clinical Dermatology
Yan, S., Yu, Z., Primiero, C., Vico-Alonso, C., Wang, Z., Yang, L., Tschandl, P., Hu, M., Ju, L., Tan, G., et al. (2025) · Nature Medicine · doi:10.1038/s41591-025-03747-y · Cited by 117 · see citing works
“This approach contrasts with previous efforts, such as SwAVDerm 35 , which relied on web-sourced skin data, inad-vertently incorporating images from commonly used benchmarks such as ISIC 55 and DermNet 44 , increasing the risk of data leakage and compromising evaluation validity.”
InfluentialSelf-citationOlayah, F., Senan, E. M., Ahmed, I. A., & Awaji, B. (2023) · Diagnostics · doi:10.3390/diagnostics13071314 · Cited by 97 · see citing works
Accuracy of a smartphone application for triage of skin lesions based on machine learning algorithms
Udrea, A., Mitra, G. D., Costea, D., Noels, E. C., Wakkee, M., Siegel, D. M., de Carvalho, T. M., & Nijsten, T. E. C. (2020) · Journal of the European Academy of Dermatology and Venereology · doi:10.1111/jdv.15935 · Cited by 96 · see citing works
Effects of Label Noise on Deep Learning-Based Skin Cancer Classification
Hekler, A., Kather, J. N., Krieghoff-Henning, E., Utikal, J. S., Meier, F., Gellrich, F. F., Upmeier zu Belzen, J., French, L., Schlager, J. G., Ghoreschi, K., et al. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00177 · Cited by 58 · see citing works
Deep Learning Approach for Medical Image Analysis
Adegun, A. A., Viriri, S., & Ogundokun, R. O. (2021) · Computational Intelligence and Neuroscience · doi:10.1155/2021/6215281 · Cited by 52 · see citing works
Naeem, A., & Anees, T. (2024) · PLoS ONE · doi:10.1371/journal.pone.0297667 · Cited by 48 · see citing works
De, A., Mishra, N., & Chang, H.-T. (2024) · PeerJ Computer Science · doi:10.7717/peerj-cs.1884 · Cited by 42 · see citing works
Self-citationClaret, S. P. A., Dharmian, J. P., & Manokar, A. M. (2024) · Egyptian Journal of Medical Human Genetics · doi:10.1186/s43042-024-00522-5 · Cited by 40 · see citing works
Zhong, F., He, K., Ji, M., Chen, J., Gao, T., Li, S., Zhang, J., & Li, C. (2024) · Scientific Reports · doi:10.1038/s41598-024-59436-2 · Cited by 37 · see citing works
<i>auto</i>SMIM: Automatic Superpixel-Based Masked Image Modeling for Skin Lesion Segmentation
Wang, Z., Lyu, J., & Tang, X. (2023) · IEEE Transactions on Medical Imaging · doi:10.1109/tmi.2023.3290700 · Cited by 35 · see citing works
Pre-training in Medical Data: A Survey
Qiu, Y., Lin, F., Chen, W., & Xu, M. (2023) · Machine Intelligence Research · doi:10.1007/s11633-022-1382-8 · Cited by 30 · see citing works
Nunnari, F., Bhuvaneshwara, C., Ezema, A. O., & Sonntag, D. (2020) · Lecture Notes in Computer Science · doi:10.1007/978-3-030-57321-8_11 · Cited by 24 · see citing works
Yue, G., Wei, P., Zhou, T., Song, Y., Zhao, C., Wang, T., & Lei, B. (2024) · IEEE Journal of Biomedical and Health Informatics · doi:10.1109/jbhi.2023.3319516 · Cited by 24 · see citing works
Aksoy, S., Demircioglu, P., & Bogrekci, I. (2024) · Dermato · doi:10.3390/dermato4040015 · Cited by 20 · see citing works
Enhancing skin lesion classification: a CNN approach with human baseline comparison
Ajabani, D., Shaikh, Z. A., Yousef, A., Ali, K., & Albahar, M. A. (2025) · PeerJ Computer Science · doi:10.7717/peerj-cs.2795 · Cited by 18 · see citing works
Ahammed, S., Cui, X., Lu, W., & Yap, M. H. (2025) · 2025 IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW) · doi:10.1109/cvprw67362.2025.00027 · Cited by 12 · see citing works
Sarhan, A. M., Ali, H. A., Yasser, S., Gobara, M., Kandil, A. A., Sherif, G., & Moustafa, E. (2025) · Journal of Electrical Systems and Information Technology · doi:10.1186/s43067-025-00243-8 · Cited by 14 · see citing works
Fair Machine Learning in Healthcare: A Survey
Feng, Q., Du, M., Zou, N., & Hu, X. (2025) · IEEE Transactions on Artificial Intelligence · doi:10.1109/tai.2024.3361836 · Cited by 12 · see citing works
Multimodal dual-stage feature refinement for robust skin lesion classification
Khurshid, M., Singh, R., & Vatsa, M. (2025) · Scientific Reports · doi:10.1038/s41598-025-14839-7 · Cited by 13 · see citing works
Machine learning approaches for skin neoplasm diagnosis
Asaduzzaman, A., Thompson, C. C., & Uddin, M. J. (2024) · ACS Omega · doi:10.1021/acsomega.4c03640 · Cited by 3 · see citing works
Kanber, B. M., Gou, S., Liu, B., Noaman, N. F., Mukred, M., & Al Smadi, A. (2026) · Neurocomputing · doi:10.1016/j.neucom.2026.134426
- Authors
- Codella, N. C. F., Gutman, D., Celebi, M. E., Helba, B., Marchetti, M. A., Dusza, S. W., Kalloo, A., Liopyris, K., Mishra, N., Kittler, H., & Halpern, A.
- Affiliations
- IBM (United States) (US)
- Emory University (US)
- University of Central Arkansas (US)
- Kitware (United States) (US)
- Memorial Sloan Kettering Cancer Center (US)
- Missouri University of Science and Technology (US)
- Medical University of Vienna (AT)
- ORCID
- Venue
- 2018 IEEE 15th International Symposium on Biomedical Imaging (ISBI 2018)
- Publisher
- IEEE
- Published
- 2018-04
- Pages
- 168-172
- OpenAlex
- W2346705140
- Cited by
- 2,620
- References
- 4
- Citations by year
- 2026: 335 · 2025: 402 · 2024: 402 · 2023: 336 · 2022: 263 · 2021: 284 · 2020: 228 · 2019: 188 · 2018: 131 · 2017: 44 · 2016: 5
- FWCI
- 448.07
- Type
- conference paper
- Language
- en
- Open access
- green
- arxiv.org
- Locations
- IEEE International Symposium on Biomedical Imaging (ISBI) (publishedVersion)
- arXiv (Cornell University) (submittedVersion)
- arXiv (Cornell University)
- Topics
- Health Sciences › Medicine › Oncology › Cutaneous Melanoma Detection and Management
- Physical Sciences › Computer Science › Artificial Intelligence › AI in cancer detection
- Physical Sciences › Computer Science › Computer Vision and Pattern Recognition › Medical Image Segmentation Techniques
- Keywords
- melanoma detection, dermoscopic images, skin lesion segmentation, feature detection, skin cancer classification, benchmark challenge, automated diagnosis, ISIC dataset
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