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Cochlear Implants: System Design, Integration, and Evaluation
Open accessAbstract
As the most successful neural prosthesis, cochlear implants have provided partial hearing to more than 120000 persons worldwide; half of which being pediatric users who are able to develop nearly normal language. Biomedical engineers have played a central role in the design, integration and evaluation of the cochlear implant system, but the overall success is a result of collaborative work with physiologists, psychologists, physicians, educators, and entrepreneurs. This review presents broad yet in-depth academic and industrial perspectives on the underlying research and ongoing development of cochlear implants. The introduction accounts for major events and advances in cochlear implants, including dynamic interplays among engineers, scientists, physicians, and policy makers. The review takes a system approach to address critical issues in cochlear implant research and development. First, the cochlear implant system design and specifications are laid out. Second, the design goals, principles, and methods of the subsystem components are identified from the external speech processor and radio frequency transmission link to the internal receiver, stimulator and electrode arrays. Third, system integration and functional evaluation are presented with respect to safety, reliability, and challenges facing the present and future cochlear implant designers and users. Finally, issues beyond cochlear implants are discussed to address treatment options for the entire spectrum of hearing impairment as well as to use the cochlear implant as a model to design and evaluate other similar neural prostheses such as vestibular and retinal implants.
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Citations
Cites
Speech Recognition with Primarily Temporal Cues
Shannon, R., Zeng, F.-G., Kamath, V., Wygonski, J., & Ekelid, M. (1995) · Science · doi:10.1126/science.270.5234.303 · Cited by 3,302
Self-citationAcoustic Theory of Speech Production
Fant, G. (1971) · De Gruyter eBooks · doi:10.1515/9783110873429 · Cited by 2,966
Class E-A new class of high-efficiency tuned single-ended switching power amplifiers
Sokal, N., & Sokal, A. D. (1975) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.1975.1050582 · Cited by 2,036
Structure and function of auditory cortex: music and speech
Zatorre, R. J., Belin, P., & Penhune, V. B. (2002) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01816-7 · Cited by 1,582
van de Ven, & Haines, A. (1999) · Medical Entomology and Zoology · Cited by 1,421
Better speech recognition with cochlear implants
Wilson, B. S., Finley, C. C., Lawson, D. T., Wolford, R. D., Eddington, D. K., & Rabinowitz, W. M. (1991) · Nature · doi:10.1038/352236a0 · Cited by 1,211
Temporal information in speech: acoustic, auditory and linguistic aspects
Rosen, S. (1992) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1992.0070 · Cited by 1,142
Factors Governing the Intelligibility of Speech Sounds
French, N. R., & Steinberg, J. C. (1947) · The Journal of the Acoustical Society of America · doi:10.1121/1.1916407 · Cited by 1,137
Bryson, J. (2017) · Routledge eBooks · doi:10.4324/9781315256894-38 · Cited by 1,135
Rf, G. (1985) · Cited by 949
Research works printed but not linked: 21
- luxford, 1985, Cochlear Implants, 92105, 1
- 10.1177/000348940711600401 · DOI
- 10.1097/MAO.0b013e318184f492 · DOI
- 1997, Multichannel Cochlear Implant System Including Wearable Speech Processor
- 2003, Multichannel Cochlear Implant with Neural Response Telemetry
- 2004, Transcutaneous Power Optimization Circuit for Cochlear Implant
- 2001, Power Transfer Circuit for Implanted Devices
- 1991, Transcutaneous Power and Signal Transmission System and Methods for Increased Signal Transmission Efficiency
- 1985, Cochlear Implant System for an Auditory Prosthesis
- robert, 2002, House Ear Institute Nucleus Research Interface (HEINRI) Users Guide
- 1998, Embedded Data Link and Protocol
- ricketts, 2002, Middle Ear Implants, 6
- 10.1097/01.mlg.0000167993.05007.35 · DOI
- 10.1080/00016480260000021 · DOI
- fraysse, 1998, Cochlear implants for adults obtaining marginal benefit from acoustic amplification, Am J Otol, 19, 591
- 10.1007/s101620020013 · DOI
- 10.1002/cii.45 · DOI
- 2006, Digitally Controlled RF Amplifier with Wide Dynamic Range Output
- 2001, High Compliance Output Stage for a Tissue Stimulator
- 2001, Programmable Current Output Stimulus Stage for Implantable Device
- 2006, Remote Control Unit for Use with an Implantable Neural Stimulator
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Development of a Multi-Channel Piezoelectric Acoustic Sensor Based on an Artificial Basilar Membrane
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Jiang, D., Demosthenous, A., Perkins, T. A., Liu, X., & Donaldson, N. (2011) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2011.2138139 · Cited by 54
μLED‐based optical cochlear implants for spectrally selective activation of the auditory nerve
Dieter, A., Klein, E., Keppeler, D., Jablonski, L., Harczos, T., Hoch, G., Rankovic, V., Paul, O., Jeschke, M., Ruther, P., et al. (2020) · EMBO Molecular Medicine · doi:10.15252/emmm.202012387 · Cited by 57
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Wang, Y., Bergeson, T. R., & Houston, D. M. (2017) · Journal of Speech Language and Hearing Research · doi:10.1044/2017_jslhr-h-17-0149 · Cited by 53
Zhang, G., Chen, R., Ghorbani, H., Li, W., Minasyan, A., Huang, Y., Lin, S., & Shao, M. (2025) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10752 · Cited by 58
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Liu, Y.-W. (2012) · InTech eBooks · doi:10.5772/37727 · Cited by 52
MEMS Capacitive Accelerometer-Based Middle Ear Microphone
Young, D. J., Zurcher, M. A., Semaan, M. T., Megerian, C. A., & Ko, W. H. (2012) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2012.2195782 · Cited by 51
Lumbreras, V., Bas, E., Gupta, C., & Rajguru, S. M. (2014) · Journal of Neurophysiology · doi:10.1152/jn.00253.2014 · Cited by 50
Cochlear implants: current status and future potential
Cosetti, M. K., & Waltzman, S. B. (2011) · Expert Review of Medical Devices · doi:10.1586/erd.11.12 · Cited by 51
Biomimetic Artificial Basilar Membranes for Next‐Generation Cochlear Implants
Jang, J., Jang, J. H., & Choi, H. (2017) · Advanced Healthcare Materials · doi:10.1002/adhm.201700674 · Cited by 51
Ahmadi, M. M., & Ghandi, S. (2018) · IEEE Sensors Journal · doi:10.1109/jsen.2018.2851605 · Cited by 51
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Kokkinakis, K., Azimi, B., Hu, Y., & Friedland, D. R. (2012) · Trends in Amplification · doi:10.1177/1084713812456906 · Cited by 50
Finke, M., Strauß-Schier, A., Kludt, E., Büchner, A., & Illg, A. (2017) · Hearing Research · doi:10.1016/j.heares.2017.03.002 · Cited by 50
Wang, S.-H., & Hung, C.-C. (2020) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2020.2982912 · Cited by 50
Fletcher, M. D., Mills, S. R., & Goehring, T. (2018) · Trends in Hearing · doi:10.1177/2331216518797838 · Cited by 48
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Klosterhoff, B. S., Tsang, M., She, D., Ong, K. G., Allen, M. G., Willett, N. J., & Guldberg, R. E. (2016) · Journal of Biomechanical Engineering · doi:10.1115/1.4035436 · Cited by 47
A High-Efficiency ASK-Modulated Class-E Power and Data Transmitter for Medical Implants
Ahmadi, M. M., Pezeshkpour, S., & Kabirkhoo, Z. (2021) · IEEE Transactions on Power Electronics · doi:10.1109/tpel.2021.3092829 · Cited by 48
Laughlin, M. M., Lu, T., Dimitrijevic, A., & Zeng, F. (2012) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2012.2186982 · Cited by 47
Self-citationRecent Advances in Cochlear Implant Electrode Array Design Parameters
Ertaş, Y. N., Ozpolat, D., Karasu, S. N., & Ashammakhi, N. A. (2022) · Micromachines · doi:10.3390/mi13071081 · Cited by 48
Hsieh, C., & Ker, M. (2021) · IEEE Transactions on Biomedical Circuits and Systems · doi:10.1109/tbcas.2021.3087036 · Cited by 46
Wang, S.-H., Huang, Y.-K., Chen, C.-Y., Tang, L.-Y., Tu, Y.-F., Chang, P.-C., Lee, C.-F., Yang, C., Hung, C.-C., Liu, C., et al. (2021) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2021.3087629 · Cited by 46
Noise Reduction in Cochlear Implant Signal Processing: A Review and Recent Developments
Henry, F., Glavin, M., & Jones, E. (2021) · IEEE Reviews in Biomedical Engineering · doi:10.1109/rbme.2021.3095428 · Cited by 46
Gels, jets, mosquitoes, and magnets: a review of implantation strategies for soft neural probes
Apollo, N. V., Murphy, B. B., Prezelski, K., Driscoll, N., Richardson, A. G., Lucas, T. H., & Vitale, F. (2020) · Journal of Neural Engineering · doi:10.1088/1741-2552/abacd7 · Cited by 47
Hanekom, T., & Hanekom, J. J. (2016) · Network Computation in Neural Systems · doi:10.3109/0954898x.2016.1171411 · Cited by 45
Efficient ASK Data and Power Transmission by the Class-E With a Switchable Tuned Network
Navaii, M. L., Sadjedi, H., & Sarrafzadeh, A. (2018) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2018.2808189 · Cited by 45
An RF-Powered FDD Radio for Neural Microimplants
Rajavi, Y., Taghivand, M., Aggarwal, K., Ma, A., & Poon, A. S. Y. (2017) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2016.2645601 · Cited by 43
Speech and Language Outcomes in Adults and Children with Cochlear Implants
Tamati, T. N., Pisoni, D. B., & Moberly, A. C. (2022) · Annual Review of Linguistics · doi:10.1146/annurev-linguistics-031220-011554 · Cited by 42
Progress on Medical Implant: A Review and Prospects
Pandey, A., & Sahoo, S. (2022) · Journal of Bionic Engineering · doi:10.1007/s42235-022-00284-z · Cited by 41
Audio-visual temporal perception in children with restored hearing
Gori, M., Chilosi, A. M., Forlì, F., & Burr, D. C. (2017) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2017.03.025 · Cited by 42
Kim, S., Song, W. J., Jang, J., Jang, J. H., & Choi, H. (2013) · Journal of Micromechanics and Microengineering · doi:10.1088/0960-1317/23/9/095018 · Cited by 40
A Novel Current Source Gate Driver for ultra-low voltage applications
Mashhadi, I. A., Ovaysi, E., Adib, E., & Farzanehfard, H. (2016) · IEEE Transactions on Industrial Electronics · doi:10.1109/tie.2016.2554539 · Cited by 40
Bioinspired Soft Elastic Metamaterials for Reconstruction of Natural Hearing
Tang, H., Zhang, S., Tian, Y., Kang, T., Zhou, C., Yang, S., Liu, Y., Liu, X., Chen, Q.-C., Xiao, H., et al. (2023) · Advanced Science · doi:10.1002/advs.202207273 · Cited by 39
Magnetic Guidance of Cochlear Implants: Proof-of-Concept and Initial Feasibility Study
Clark, J. R., Leon, L., Warren, F. M., & Abbott, J. J. (2012) · Journal of Medical Devices · doi:10.1115/1.4007099 · Cited by 39
Tinnitus suppression by electric stimulation of the auditory nerve
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Speech enhancement based on neural networks applied to cochlear implant coding strategies
Bolner, F., Goehring, T., Monaghan, J. J. M., van Dijk, B., Wouters, J. M., & Bleeck, S. (2016) · IEEE International Conference on Acoustics Speech and Signal Processing · doi:10.1109/icassp.2016.7472933 · Cited by 38
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Ghosh, R., Ali, H., & Hansen, J. H. L. (2021) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2021.3123241 · Cited by 38
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Mamun, N., Khorram, S., & Hansen, J. H. L. (2019) · Interspeech (USB) · doi:10.21437/interspeech.2019-1850 · Cited by 37
Nogueira, W., Dolhopiatenko, H., Schierholz, I., Büchner, A., Mirkovic, B., Bleichner, M. G., & Debener, S. (2019) · Frontiers in Neuroscience · doi:10.3389/fnins.2019.00720 · Cited by 37
EEG-based diagnostics of the auditory system using cochlear implant electrodes as sensors
Somers, B., Long, C. J., & Francart, T. (2021) · Scientific Reports · doi:10.1038/s41598-021-84829-y · Cited by 37
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Eshraghi, A. A., Gupta, C., Özdamar, Ö., Bałkany, T. J., Truy, É., & Nazarian, R. (2012) · The Anatomical Record · doi:10.1002/ar.22584 · Cited by 36
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Won, J. H., Humphrey, E. L., Yeager, K. R., Martinez, A. A., Robinson, C. H., Mills, K. E. T., Johnstone, P. M., Moon, I. J., & Woo, J. (2014) · The Journal of the Acoustical Society of America · doi:10.1121/1.4895702 · Cited by 34
Development and Characterization of a Sucrose Microneedle Neural Electrode Delivery System
Apollo, N. V., Jiang, J. L., Cheung, W., Baquier, S. H., Lai, A., Mirebedini, A., Foroughi, J., Wallace, G. G., Shivdasani, M. N., Prawer, S., et al. (2017) · Advanced Biosystems · doi:10.1002/adbi.201700187 · Cited by 34
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Trevlakis, S. E., Boulogeorgos, A. A., Sofotasios, P. C., Muhaidat, S., & Karagiannidis, G. K. (2019) · Biomedical Optics Express · doi:10.1364/boe.10.000707 · Cited by 33
Leake, P. A., Rebscher, S. J., Dore‘, C., & Akil, O. (2019) · Journal of the Association for Research in Otolaryngology · doi:10.1007/s10162-019-00723-5 · Cited by 33
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Latif, R., Noor, M. M., Yunas, J., & Hamzah, A. A. (2021) · Polymers · doi:10.3390/polym13142276 · Cited by 32
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Takeda, K., & Torikai, H. (2020) · IEEE Transactions on Circuits and Systems I Regular Papers · doi:10.1109/tcsi.2020.2971786 · Cited by 31
Beker, L., Zorlu, Ö., Göksu, N., & Külah, H. (2013) · International Conference on Solid-State Sensors, Actuators and Microsystems · doi:10.1109/transducers.2013.6627104 · Cited by 30
Dalrymple, A. N., Huynh, M., Robles, U. A. A., Marroquin, J. B., Lee, C. D., Petrossians, A., Whalen, J. J., Li, D., Parkington, H. C., Forsythe, J. S., et al. (2019) · Journal of Neural Engineering · doi:10.1088/1741-2552/ab5163 · Cited by 30
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Qian, X.-H., Lee, Y.-C., Chang, J.-H., Lin, S., Li, S., Wu, T.-C., Huang, C., Wang, S.-H., Lee, C.-F., Yang, C., et al. (2019) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2019.2901374 · Cited by 27
Intartaglia, B., Zeitnouni, A. G., & Lehmann, A. (2022) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2022.109592 · Cited by 27
Applications and challenges of rhodopsin-based optogenetics in biomedicine
Zhang, H., Fang, H., Liu, D., Zhang, Y., Adu‐Amankwaah, J., Yuan, J., Tan, R., & Zhu, J. (2022) · Frontiers in Neuroscience · doi:10.3389/fnins.2022.966772 · Cited by 27
Implications of Neural Plasticity in Retinal Prosthesis
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Advances in Microelectronics for Implantable Medical Devices
Demosthenous, A. (2014) · Advances in Electronics · doi:10.1155/2014/981295 · Cited by 29
In vivo microelectrode arrays for neuroscience
Williams, N. P., Vöröslakos, M., Shi, D., Pwint, M. Y., Lanzio, V., Mao, H., Zolotavin, P., Yoon, E., Stieglitz, T., Xie, C., et al. (2025) · Nature Reviews Methods Primers · doi:10.1038/s43586-025-00399-7 · Cited by 30
Optogenetic Stimulation of the Auditory Nerve
Hernández, V. H., Gehrt, A., Jing, Z., Hoch, G., Jeschke, M., Strenzke, N., & Moser, T. (2014) · Journal of Visualized Experiments · doi:10.3791/52069 · Cited by 26
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Won, J.-H., Moon, I. J., Jin, S.-H., Park, H., Woo, J., Cho, Y., Chung, W., & Hong, S. H. (2015) · PLoS ONE · doi:10.1371/journal.pone.0140920 · Cited by 26
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Nogueira, W., Cosatti, G., Schierholz, I., Egger, M., Mirkovic, B., & Büchner, A. (2019) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2019.2907638 · Cited by 26
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Chen, H., & Conn, A. T. (2020) · IEEE Sensors Journal · doi:10.1109/jsen.2020.2979076 · Cited by 26
Wong, P., George, S. S., Tran, P., Sue, A., Carter, P., & Li, Q. (2015) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2015.2480601 · Cited by 26
A 10 mm3Inductive Coupling Radio for Syringe-Implantable Smart Sensor Nodes
Shi, Y. H., Choi, M., Li, Z., Luo, Z., Kim, G., Foo, Z., Kim, H.-S., Wentzloff, D. D., & Blaauw, D. T. (2016) · IEEE Journal of Solid-State Circuits · doi:10.1109/jssc.2016.2606162 · Cited by 26
Danilov, A. A., Рафаэльевич, А. Р., Mindubaev, E. A., Олегович, Г. К., Telyshev, D. V., & Selishchev, S. V. (2019) · IEEE Access · doi:10.1109/access.2019.2919259 · Cited by 26
Stochastic resonance in the sensory systems and its applications in neural prosthetics
Matthews, P., Raul, P., Ward, L. M., & van Boxtel, J. J. A. (2024) · Clinical Neurophysiology · doi:10.1016/j.clinph.2024.07.004 · Cited by 26
Hannan, M. A., Hussein, H. M., Mutashar, S., Samad, S. A., & Hussain, A. (2014) · Sensors · doi:10.3390/s141223843 · Cited by 25
Huang, J., Lu, T., Sheffield, B. M., & Zeng, F. (2019) · Ear and Hearing · doi:10.1097/aud.0000000000000749 · Cited by 25
Self-citation
Metadata
- Authors
- Zeng, F.-G., Rebscher, S., Harrison, W., Sun, X., & Feng, H.
- Affiliations
- University of California, Irvine (US)
- University of California, San Francisco (US)
- Silere Med. Technol., Inc., Kirkland, WA
- Nurotron Biotechnol. Inc., Irvine, CA
- Chinese Academy of Sciences (CN)
- Corresponding author
- Zeng, Fan-Gang
- Venue
- IEEE Reviews in Biomedical Engineering
- Published
- 2008
- Volume
- 1
- Pages
- 115-142
- ISSN
- 1937-3333 (ISSN-L)
- 1941-1189
- PMC
- PMC2782849
- OpenAlex
- W2112854909
- Cited by
- 878
- References
- 227
- Citations by year
- 2026: 60 · 2025: 75 · 2024: 65 · 2023: 62 · 2022: 57 · 2021: 79 · 2020: 69 · 2019: 70 · 2018: 50 · 2017: 48 · 2016: 44 · 2015: 39 · 2014: 43 · 2013: 40 · 2012: 27
- FWCI
- 1.24
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Licence
- Locations
- IEEE Reviews in Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (HHS-N-263-2007-00054-C, 5r01dc008858-05)
- U.S. Public Health Service (HHSN-263-2007-00054C)
- National Institute on Deafness and Other Communication Disorders (P30DC008369, HHSN263200700054C, R01-DC008858, R01DC002267)
- Topics
- Health Sciences › Health Professions › Speech and Hearing › Hearing Loss and Rehabilitation
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Computer Science › Signal Processing › Speech and Audio Processing
- Keywords
- cochlear implants, neural prostheses, hearing loss, system design, radio frequency transmission, stimulator, electrode arrays, system integration, safety and reliability, functional assessment, pediatric cochlear implant users, vestibular implant, retinal prosthesis
- MeSH terms
- Animals, Cochlear Implants, Humans, Prosthesis Design
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