Cited by 105Advanced Chemical Sensor TechnologiesSpectroscopy and Laser ApplicationsArtificial Intelligence in Healthcare

Recent Advancements and Future Prospects on E-Nose Sensors Technology and Machine Learning Approaches for Non-Invasive Diabetes Diagnosis: A Review

Lekha, S., M, Suchetha·2021·IEEE Reviews in Biomedical Engineering

Abstract

Diabetes mellitus, commonly measured through an invasive process which although is accurate, has manifold drawbacks especially when multiple reading are required at regular intervals. Accordingly, there is a need to develop a dependable non-invasive diabetes detection technique. Recent studies have observed that other human serums such as tears, saliva, urine and breath indicate the presence of glucose in them. These parameters open quite a few ways for non-invasive blood glucose level prediction. The analysis of a persons breath poses as a good non-invasive technique to monitor the glucose levels. It is seen that in breath, there are many bio-markers and monitoring the levels of these bio-markers indicate the possibility of various chronic diseases. Among these bio-markers, acetone a volatile organic compound found in breath has shown a good correlation to the glucose levels present in blood. Therefore, by evaluating the acetone levels in breath samples it is possible to monitor diabetes non-invasively. This paper reviews the various approaches and sensory techniques used to monitor diabetes though human breath samples.

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Crossref · 10.1109/rbme.2020.2993591

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Authors
Lekha, S., & M, S.
Affiliations
Vellore Institute of Technology University (IN)
Venue
IEEE Reviews in Biomedical Engineering
Published
2021
Volume
14
Pages
127-138
ISSN
  • 1937-3333 (ISSN-L)
  • 1941-1189
OpenAlex
W3024571102
Cited by
105
References
91
Citations by year
2026: 7 · 2025: 27 · 2024: 25 · 2023: 25 · 2022: 10 · 2021: 10 · 2020: 1
FWCI
0.96
Type
journal article
Language
en
Open access
closed
Locations
  • IEEE Reviews in Biomedical Engineering (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Engineering › Biomedical Engineering › Advanced Chemical Sensor Technologies
  • Physical Sciences › Chemistry › Spectroscopy › Spectroscopy and Laser Applications
  • Health Sciences › Health Professions › Health Information Management › Artificial Intelligence in Healthcare
Keywords
electronic nose, breath analysis, acetone, volatile organic compounds, blood glucose monitoring, machine learning, breath biomarkers, diabetes mellitus
MeSH terms
Machine Learning, Acetone, Breath Tests, Diabetes Mellitus, Glucose, Humans, Monitoring, Physiologic, Signal Processing, Computer-Assisted, Biosensing Techniques, Biomarkers, Electronic Nose

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