Mechanical factors in the design of chronic recording intracortical microelectrodes
Abstract
To obtain chronic recordings from single nerve cells in the cerebral cortex it is necessary to prevent motion of the microelectrode tip with respect to the adjacent neural tissue. This paper presents an engineering analysis to estimate these motions in terms of the geometry and material properties of the electrode, its lead wire, and the cortex. The results are used to gain an understanding of a recently reported successful recording system, and to thereby provide a design guide for future systems. In addition, a buckling analysis is presented for a class of microelectrodes to enable a minimum size to be achieved with an adequate safety margin.
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As implants fail to move together with tissue, compression and sliding along the interface cause damage to surrounding tissue.
“As implants fail to move together with tissue, the compression and sliding along the interface causes damage to the surrounding tissue (Goldstein and Salcman, 1973; Sharp et al., 2009; Barrese et al., 2016).”
From Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics (2021) · cites this paper as Goldstein and Salcman, 1973
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- Authors
- Goldstein, S. R., & Salcman, M.
- Affiliations
- United States Department of Health and Human Services (US)
- NewYork–Presbyterian Hospital (US)
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 1973-07
- Volume
- BME-20
- Issue
- 4
- Pages
- 260-269
- ISSN
- 0018-9294 (ISSN-L)
- OpenAlex
- W1978266133
- Cited by
- 53
- References
- 9
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2022: 1 · 2021: 4 · 2020: 3 · 2019: 5 · 2018: 4 · 2017: 2 · 2016: 4 · 2015: 2 · 2014: 4 · 2013: 1 · 2012: 3
- FWCI
- 0.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- IEEE Transactions on Biomedical Engineering (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
- Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
- Physical Sciences › Engineering › Electrical and Electronic Engineering › Advanced MEMS and NEMS Technologies
- Keywords
- intracortical microelectrodes, chronic neural recording, mechanical design, buckling analysis, electrode geometry, lead wire, cerebral cortex, single-unit recording
- MeSH terms
- Animals, Haplorhini, Biomedical Engineering, Electrodes, Implanted, Mathematics, Microelectrodes, Motion
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