CoChat
Sign Up
Cited by 115Neuroscience and Neural EngineeringAnalog and Mixed-Signal Circuit DesignUndergraduate Neuroscience Education and Research

The future of neuroscience: flexible and wireless implantable neural electronics

Open access
McGlynn, Eve, Nabaei, Vahid, Ren, Elisa, Galeote‐Checa, Gabriel, Das, Rupam, Curia, Giulia, Heidari, Hadi·2021·Advanced Science
DOI 10.1002/advs.202002693PMC PMC8132070
Open this paper in CoChat — free accountOpen PDF

Abstract

Neurological diseases are a prevalent cause of global mortality and are of growing concern when considering an ageing global population. Traditional treatments are accompanied by serious side effects including repeated treatment sessions, invasive surgeries, or infections. For example, in the case of deep brain stimulation, large, stiff, and battery powered neural probes recruit thousands of neurons with each pulse, and can invoke a vigorous immune response. This paper presents challenges in engineering and neuroscience in developing miniaturized and biointegrated alternatives, in the form of microelectrode probes. Progress in design and topology of neural implants has shifted the goal post toward highly specific recording and stimulation, targeting small groups of neurons and reducing the foreign body response with biomimetic design principles. Implantable device design recommendations, fabrication techniques, and clinical evaluation of the impact flexible, integrated probes will have on the treatment of neurological disorders are provided in this report. The choice of biocompatible material dictates fabrication techniques as novel methods reduce the complexity of manufacture. Wireless power, the final hurdle to truly implantable neural interfaces, is discussed. These aspects are the driving force behind continued research: significant breakthroughs in any one of these areas will revolutionize the treatment of neurological disorders.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1002/advs.202002693

Cites

375 of 375 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The length of the cable can be a limiting factor in terms of mobility and comfort for human subjects, rodents or primates, affecting natural behavior of animals in experiments and potentially affecting the results.

    “However, the length of the cable can be a limiting factor in terms of mobility and comfort both for human subjects, rodents or primates affecting natural behavior of animals in experiments thus potentially affecting the results (McGlynn et al., 2021).”

    From Comparative analysis of energy transfer mechanisms for neural implants (2024) · cites this paper as McGlynn et al., 2021

    The ‘Untethered’ section (page unavailable) says physical tethers hamper animals’ natural behavior during experiments and that this matters when studying an implant’s neurological effects. ‘Energy Transfer and Harvesting’ also says wired devices may impede test animals’ movement, including rats. The paper does not specifically attribute those limitations to cable length or address comfort and mobility in human subjects or primates. (LLM, conf=0.85)

    Experimental — accuracy not yet measured

  • Wireless power transmission advancements could reduce the need for bulky batteries.

    “Wireless power transmission advancements could reduce the need for bulky batteries (McGlynn et al., 2021).”

    From Comparative analysis of energy transfer mechanisms for neural implants (2024) · cites this paper as McGlynn et al., 2021

  • Wired connections can affect micromotion inside the brain.

    “Moreover, there are concerns that wired connections can affect micromotion inside the brain (McGlynn et al., 2021)”

    From Comparative analysis of energy transfer mechanisms for neural implants (2024) · cites this paper as McGlynn et al., 2021

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

2 of the 377 references couldn’t be matched to a known paper.

Research works printed but not linked: 377

  1. [1]X. L. Chen, Y. Y. Xiong, G. L. Xu, X. F. Liu, Interv. Neurol. 2013, 1, 3. PMC4031775 25187779
  2. [2]X. Yang, T. Zhou, G. S. Hong, Y. Zhao, R. D. Viveros, T. M. Fu, T. Gao, C. M. Lieber, Nat. Mater. 2019, 18, 5. PMC6474791 30804509
  3. [3]G. N. D. C. Group, Lancet 2017, 16, 11.
  4. [4]K. J. Seo, P. Artoni, Y. Zhong, X. Han, Z. Shi, W. Yao, M. Fagiolini, H. Fang, Adv. Biosyst. 2019, 3, 3. 32627399
  5. [5]L. Karumbaiah, T. Saxena, D. Carlson, K. Patila, R. Patkara, E. A. Gaupp, M. Betancur, G. B. Stanley, L. Carin, R. V. Bellamkonda, Biomaterials 2013, 34, 8061. 23891081
  6. [6]J. M. Schwalb, C. Hamani, Neurotherapeutics 2008, 5, 1. PMC5084122 18164479
  7. [7]J. M. R. Delgado, in Electrical Stimulation of the Brain. An Interdisciplinary Survey of Neurobehavior, Vol. 2 (Ed: D. E. Sheer), University of Texas Press, Austin, TX 1961, pp. 25– 36.
  8. [10]D. Shahriari, D. Rosenfeld, P. Anikeeva, Neuron 2020, 108, 270. 33120023
  9. [11]D. Prodanov, J. Delbeke, Front. Neurosci. 2016, 10, 11. 26903786 PMC4746296
  10. [12]A. Lecomte, E. Descamps, C. Bergaud, J. Neural Eng. 2018, 15, 3. 28885187
  11. [13]E. Mariani, G. Lisignoli, R. M. Borzi, L. Pulsatelli, Int. J. Mol. Sci. 2019, 20, 636. PMC6386828 30717232
  12. [14]K. Tybrandt, D. Khodagholy, B. Dielacher, F. Stauffer, A. F. Renz, G. Buzsáki, J. Vörös, Adv. Mater. 2018, 30, 1706520. PMC5948103 29488263
  13. [15]M. Umair, I. Javed, M. Rehman, A. Madni, A. Javeed, A. Ghafoor, M. Ashraf, J. Pharm. Pharm. Sci. 2016, 19, 2. 27518167
  14. [16]H. A. Sackeim, JAMA Psychiatry. 2017, 74, 779. 28658461
  15. [17]C. Mohn, B. R. Rund, J. Affective Disord. 2016, 202. 27253211
  16. [18]C. Griffiths, A. O'Neill‐Kerr, Front. Psychiatry 2019, 10, 304. 31133895 PMC6514218
  17. [19]Z. Nahas, B. Short, C. Burns, M. Archer, M. Schmidt, J. Prudic, M. S. Nobler, D. Devanand, L. Fitzsimons, S. H. Lisanby, Brain Stimul. 2013, 6, 403. 23518262
  18. [20]J. Gomez, Br. J. Psychiatry 1975, 127, 6.
  19. [21]H. A. Sackeim, Clin. Neurosci. Rev. 2004, 4, 1.
  20. [22]J. C. Horvath, J. M. Perez, L. Forrow, F. Fregni, A. Pascual‐Leone, J. Med. Ethics 2011, 37, 137. 21106996
  21. [23]A. Valero‐Cabré, J. L. Amengual, C. Stengel, A. Pascual‐Leone, O. A. Coubard, Neurosci. Biobehav. Rev. 2017, 83, 381. 29032089
  22. [24]M. Hallett, Nature 2000, 406, 147. 10910346
  23. [25]M. Diana, T. Raij, M. Melis, A. Nummenmaa, L. Leggio, A. Bonci, Nat. Rev. Neurosci. 2017, 18, 685. 28951609
  24. [26]N. S. Rose, J. J. LaRocque, A. C. Riggall, O. Gosseries, M. J. Starrett, E. E. Meyering, B. R. Postle, Science 2016, 354, 1136. 27934762 PMC5221753
  25. [27]S. Hardy, L. Bastick, A. O'Neill‐Kerr, P. Sabesan, S. Lankappa, L. Palaniyappan, BJPsych. Adv. 2016, 22, 6.
  26. [28]A. Pascual‐Leone, J. Valls‐Solé, E. M. Wassermann, M. Hallett, Brain 1994, 117, 847. 7922470
  27. [29]A. Pascual‐Leone, J. M. Tormos, J. Keenan, F. Tarazona, C. Cañete, M. D. Catalá, J. Clin. Neurophys. 1998, 15, 4. 9736467
  28. [30]C. Griffiths, K. da Silva, R. De Vai, A. O'Neill‐Kerr, Open J. Depression 2019, 8, 59.
  29. [31]B. Manor, P. E. Greenstein, P. Davila‐Perez, S. Wakefield, J. Zhou, A. Pascual‐Leone, Front. Neurol. 2019, 10, 73. 30809184 PMC6380199
  30. [32]M. G. Christiansen, A. W. Senko, P. Anikeeva, Ann. Rev. Neurosci. 2019, 42, 271. 30939100 PMC6617523
  31. [33]G. Bonmassar, S. W. Lee, D. K. Freeman, M. Polasek, S. I. Fried, J. T. Gale, Nat. Commun. 2012, 3, 921. 22735449 PMC3621430
  32. [34]S. W. Lee, S. I. Fried, in Int. Conf. of the IEEE Engineering in Medicine and Biology Society, IEEE, Piscataway, NJ 2014.
  33. [35]D. C. Rodger, J. D. Weiland, M. S. Humayun, Y.‐C. Tai, Sens. Actuators B 2006, 117, 107.
  34. [36]S. W. Lee, J.‐M. Seo, S. Ha, E. T. Kim, H. Chung, S. J. Kim, Invest. Opthalmol. Vis. Sci. 2009, 50, 12. 19553608
  35. [37]S. W. Lee, K. S. Min, J. Jeong, J. Kim, S. J. Kim, IEEE Trans. Biomed. Eng. 2011, 58, 8.
  36. [38]S. W. Lee, F. Fallegger, B. D. F. Casse, S. I. Fried, Sci. Adv. 2016, 2, e1600889. 27957537 PMC5148213
  37. [39]H. Park, H. Kang, J. Jo, E. Chung, S. Kim, Sci. Rep‐UK 2018, 8, 13423. PMC6128857 30194395
  38. [41]V. S. Polikov, P. A. Tresco, W. M. Reichert, J. Neurosci. Methods 2005, 148, 1. 16198003
  39. [42]S. F. Cogan, Annu. Rev. Biomed. Eng. 2008, 10, 275. 18429704
  40. [43]S. F. Cogan, K. A. Ludwig, C. G. Welle, P. Takmakov, J. Neural Eng. 2016, 13, 2. PMC5386002 26792176
  41. [44]S. Kim, P. Tathireddy, R. A. Normann, F. Solzbacher, in Int. IEEE/EMBS Conf. on Neural Engineering, IEEE, Piscataway, NJ 2007. 18198706
  42. [45]M. L. Kringelbach, N. Jenkinson, S. L. Owen, T. Z. Aziz, Nat. Rev. Biosci. 2007, 8, 8. 17637800
  43. [46]A. Gautam, M. Rai, R. Srivastava, B. jyoti, P. K. Priyadarshi, IJCMSR 2018, 3, 3.
  44. [47]T. M. Herrington, J. J. Cheng, E. N. Eskandar, J. Neurophys. 2016, 115, 19. PMC4760496 26510756
  45. [48]A. Ramirez‐Zamora, J. L. Ostrem, JAMA Neurol. 2018, 75, 367. 29356826
  46. [49]S. M. Falowski, R. A. Bakay, Neuromodulation: Technol. Neural Interface 2016, 19, 5. 26899800
  47. [50]A. Boutet, C. T. Chow, K. Narang, G. J. Elias, C. Neudorfer, J. Germann, M. Ranjan, A. Loh, A. J. Martin, W. Kucharczyk, Radiology 2020, 296, 250. 32573388 PMC7543718
  48. [51]L. Golestanirad, J. Kirsch, G. Bonmassar, S. Downs, B. Elahi, A. Martin, M.‐I. Iacono, L. M. Angelone, B. Keil, L. L. Wald, NeuroImage 2019, 184, 566. 30243973 PMC6475594
  49. [53]J. Rivnay, H. Wang, L. Fenno, K. Deisseroth, G. G. Malliaras, Sci. Adv. 2017, 3, e1601649. 28630894 PMC5466371
  50. [54]P. Hegemann, W. Gärtner, R. Uhl, Biophys. J. 1991, 60, 1477. 19431816 PMC1260206
  51. [55]E. S. Boyden, F. Zhang, E. Bamberg, G. Nagel, K. Deisseroth, Nat. Neurosci. 2005, 8, 1263. 16116447
  52. [56]S. M. Won, E. Song, J. T. Reeder, J. A. Rogers, Cell 2020, 181, 115. 32220309
  53. [57]B. Ji, Z. Guo, M. Wang, B. Yang, X. Wang, W. Li, J. Liu, Microsyst. Nanoeng. 2018, 4, 27. 31057915 PMC6220173
  54. [58]P. Gutruf, V. Krishnamurthi, A. Vázquez‐Guardado, Z. Xie, A. Banks, C.‐J. Su, Y. Xu, C. R. Haney, E. A. Waters, I. Kandela, Nat. Electron. 2018, 1, 652.
  55. [59]J. S. Ho, A. J. Yeh, E. Neofytou, S. Kim, Y. Tanabe, B. Patlolla, R. E. Beygui, A. S. Poon, Proc. Natl. Acad. Sci. USA 2014, 111, 22. PMC4050616 24843161
  56. [60]C. E. Tedford, S. DeLapp, S. Jacques, J. Anders, Lasers Surg. Med. 2015, 47, 4. 25772014
  57. [61]N. Yu, L. Huang, Y. Zhou, T. Xue, Z. Chen, G. Han, Adv. Healthcare Mater. 2019, 8, 6. 30633858
  58. [62]L. S. Saleh, S. J. Bryant, Curr. Opin. Biomed. Eng. 2018, 6, 58. 30374467 PMC6203342
  59. [63]H. C. Lee, F. Ejserholm, J. Gaire, S. Currlin, J. Schouenborg, L. Wallman, M. Bengtsson, K. Park, K. J. Otto, J. Neural Eng. 2017, 14, 036026. 28470152
  60. [64]S. Sommakia, H. C. Lee, J. Gaire, K. J. Otto, Curr. Opin. Solid State Mater. Sci. 2014, 18, 319. 25530703 PMC4267064
  61. [65]J. P. Harris, D. J. Tyler, Crit. Rev. Biomed. Eng. 2013, 41, 6. 24940658
  62. [66]H. Neumann, M. R. Kotter, R. J. M. Franklin, Brain 2009, 132, 2. PMC2640215 18567623
  63. [67]L. A. Struzyna, K. Katiyar, D. K. Cullen, Curr. Opin. Solid State Mater. 2014, 18, 308. PMC5520662 28736499
  64. [68]J. M. Anderson, A. Rodriguez, D. T. Chang, Semin. Immunol. 2008, 20, 86. 18162407 PMC2327202
  65. [69]J. H. Morrison, P. R. Hof, Science 1997, 278, 412. 9334292
  66. [70]I. Sack, B. Beierbach, J. Wuerfel, D. Klatt, U. Hamhaber, S. Papazoglou, P. Martus, J. Braun, NeuroImage 2009, 46, 652. 19281851
  67. [71]D. Hachim, N. Wang, S. T. Lopresti, E. C. Stahl, Y. U. Umeda, R. D. Rege, S. T. Carey, D. Mani, B. N. Brown, J. Biomed. Mater. A 2017, 105, 5. PMC5963506 28130823
  68. [72]D. O. Adewole, M. D. Serruya, J. A. Wolf, D. K. Cullen, Front. Neurosci. 2019, 13, 169. 30983957 PMC6449725
  69. [73]R. Feiner, T. Dvir, iScience 2020, 23, 100833. 31982781 PMC6994631
  70. [74]T. Elsdale, J. Bard, J. Cell Biol. 1972, 54, 626. 4339818 PMC2200288
  71. [75]C. P. Barnes, S. A. Sell, E. D. Boland, D. G. Simpson, G. L. Bowlin, Adv. Drug Delivery Rev. 2007, 59, 1413. 17916396
  72. [76]B. Cragg, Neurosci. Lett. 1979, 15, 301. 394033
  73. [77]A. Dityatev, T. Fellin, Neuron. Glia Biol. 2008, 4, 3. 19497143
  74. [78]H. Pantazopoulos, T.‐U. W. Woo, M. P. Lim, N. Lange, S. Berretta, Arch. Gen. Psychiatry 2010, 67, 155. 20124115 PMC4208310
  75. [79]H. Tomlin, A. M. Piccinini, Immunology 2018, 155, 186. 29908065 PMC6142291
  76. [80]S. M. Willerth, S. E. Sakiyama‐Elbert, Adv. Drug Delivery Rev. 2007, 59, 325. PMC1976339 17482308
  77. [81]S. Chen, M. G. Allen, MRS Bull. 2012, 37, 606.
  78. [82]C. Xie, J. Liu, T. M. Fu, X. C. Dai, W. Zhou, C. M. Lieber, Nat. Mater. 2015, 14, 12. 26436341
  79. [83]J. Thelin, H. Jorntell, E. Psouni, M. Garwicz, J. Schouenbourg, N. Danielsen, C. E. Linsmeier, PLoS One 2011, 6, e16267. 21298109 PMC3027655
  80. [84]S. Arcot Desai, C.‐A. Gutekunst, S. M. Potter, R. E. Gross, Front. Neuroeng. 2014, 7, 16. 24971060 PMC4054883
  81. [85]T. D. Y. Kozai, X. Li, L. M. Bodily, E. M. Caparosa, G. A. Zenonos, D. L. Carlisle, R. M. Friedlander, X. T. Cui, Biomaterials 2014, 35, 9620. 25176060 PMC4174599
  82. [86]J. P. Seymour, D. R. Kipke, Biomaterials 2007, 28, 3594. 17517431
  83. [87]J. L. Skousen, M. E. Merriam, O. Srivannavit, G. Perlin, K. D. Wise, P. A. Tresco, Progress Brain Res. 2011, 194, 167. 21867802
  84. [88]E. Castagnola, E. Maggiolini, L. Ceseracciu, F. Ciarpella, E. Zucchini, S. De Faveri, L. Fadiga, D. Ricci, Front. Neurosci. 2016, 10, 151. 27147944 PMC4834343
  85. [89]A. J. Shoffstall, J. R. Capadona, Curr. Opin. Biomed. Eng. 2018, 6, 110.
  86. [90]S. F. Cogan, T. D. Plante, J. Ehrlich, in The 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Vol. 2, IEEE, New Jersey, United States of America 2004, pp. 4153– 4156. PMC2709748 17271216
  87. [91]F. Deku, Y. Cohen, A. Joshi‐Imre, A. Kanneganti, T. J. Gardner, S. F. Cogan, J. Neural Eng. 2018, 15, 016007. 28952963 PMC5786446
  88. [92]N. Ullah, S. Omanovic, Mater. Chem. Phys. 2015, 159, 119.
  89. [93]D. E. Discher, P. Janmey, Y. Wang, Science 2005, 310, 1139. 16293750
  90. [94]L. A. Flanagan, Y. E. Ju, B. Marg, M. Osterfied, P. A. Janmey, Neuroreport 2002, 13, 2411. 12499839 PMC2408859
  91. [95]S. R. Goldstein, M. Salcman, IEEE Trans. Biomed. Eng. 1973, BME‐20, 260. 4196687
  92. [96]M. S. Fee, Neuron 2000, 27, 461. 11055429
  93. [97]A. Giletti, J. Muthuswamy, J. Neural Eng. 2006, 3, 3. 16921202
  94. [98]R. Britt, G. Rossi, J. Neurosci. Methods 1982, 6, 3. 7144236
  95. [99]J. K. Nguyen, D. J. Park, J. L. Skousen, A. E. Hess‐Dunning, D. J. Tyler, S. J. Rowan, C. Weder, J. R. Capadona, J. Neural Eng. 2014, 11, 5. PMC4175058 25125443
  96. [100]J. Harris, A. E. Hess, S. J. Rowan, C. Weder, C. Zorman, D. Tyler, J. R. Capadona, J. Neural Eng. 2011, 8, 4. PMC4134134 21654037
  97. [101]J. P. Harris, J. R. Capadona, R. H. Miller, B. C. Healy, K. Shanmuganathan, S. J. Rowan, C. Weder, D. J. Tyler, J. Neural Eng. 2011, 8, 6. PMC3386315 22049097
  98. [102]W. Zhang, Z. Li, M. Gilles, D. Wu, J. Med. Biol. Eng. 2014, 34, 4.
  99. [103]R. Biran, D. C. Martin, P. A. Tresco, J. Biomed. Mater. Res. 2007, 82A, 169. 17266019
  100. [105]P. Gutruf, J. A. Rogers, Curr. Opin. Neurobiol. 2018, 50. 29289027
  101. [106]G. Shin, A. M. Gomez, R. Al‐Hasani, Y. R. Jeong, J. Kim, Z. Xie, A. Banks, S. M. Lee, S. Y. Han, C. J. Yoo, J.‐L. Lee, S. H. Lee, J. Kurniawan, J. Tureb, Z. Guo, J. Yoon, S.‐I. Park, S. Y. Bang, Y. Nam, M. C. Walicki, V. K. Samineni, A. D. Mickle, K. Lee, S. Y. Heo, J. G. McCall, T. Pan, L. Wang, X. Feng, T. Kim, J. K. Kim, Y. Li, Y. Huang, R. W. Gereau, J. S. Ha, M. R. Bruchas, J. A. Rogers, Neuron 2017, 93, 509. 28132830 PMC5377903
  102. [107]Y. Zhao, C. Liu, Z. Liu, W. Luo, L. Li, X. Cai, D. Liang, Y. Su, H. Ding, Q. Wang, L. Yin, J. Guan, M. Luo, X. Sheng, IEEE Trans. Electron Dev. 2019, 66, 1.
  103. [109]F. Barz, V. Trouillet, O. Paul, P. Ruther, IEEE Trans. Biomed. Eng. 2019, 67, 5. 31442966
  104. [110]A. Schander, H. Stemmann, A. K. Kreiter, W. Lang, Proceedings, 2017, 1, 511.
  105. [111]C. J. Wilson, R. E. Clegg, D. I. Leavesley, M. J. Pearcy, Tissue Eng. 2005, 11, 1. 15738657
  106. [112]Y. K. Kim, R. Que, S.‐W. Wang, W. F. Liu, Adv. Healthcare Mater. 2014, 3, 7. PMC4272238 24573988
  107. [113]E. S. Ereifej, C. S. Smith, S. M. Meade, K. Chen, H. Feng, J. R. Capadona, Adv. Funct. Mater. 2018, 28, 1704420.
  108. [114]J. Park, S. Choi, A. H. Janardhan, S.‐Y. Lee, S. Raut, J. Soares, K. Shin, S. Yang, C. Lee, K.‐W. Kang, H. R. Cho, S. J. Kim, P. Seo, W. Hyun, S. Jung, H.‐J. Lee, N. Lee, S. H. Choi, M. Sacks, N. Lu, M. E. Josephson, T. Hyeon, D.‐H. Kim, H. J. Hwang, Sci. Trans. Med. 2016, 8, 344. 27334261
  109. [115]N. Gomez, Y. Lu, S. Chen, C. E. Schmidt, Biomaterials 2007, 28, 271. 16919328
  110. [116]L. M. Y. Yu, N. D. Leipzig, M. S. Shoichet, Mater. Today 2008, 11, 5.
  111. [117]S. D. Faveri, E. Maggiolini, E. Miele, F. De Angelis, F. Cesca, F. Benfenati, L. Fadiga, Front. Neuroeng. 2014, 7, 7. 24782757 PMC3989589
  112. [118]M. Rizwan, R. Yahya, A. Hassan, M. Yar, A. D. Azzahari, V. Selvanathan, F. Sonsudin, C. N. Abouloula, Polymers 2017, 9, 137. PMC6432076 30970818
  113. [119]L. A. Struzyna, K. Katiyar, D. K. Cullen, Curr. Opin. Solid State Mater. Sci. 2014, 18, 308. 28736499 PMC5520662
  114. [120]U. A. Aregueta‐Robles, A. J. Woolley, L. A. Poole‐Warren, N. H. Lovell, R. A. Green, Front. Neuroeng. 2014, 7, 15. 24904405 PMC4034607
  115. [121]E. S. Ereifej, G. M. Rial, J. K. Hermann, C. S. Smith, S. M. Meade, J. M. Rayyan, K. Chen, H. Feng, J. R. Capadona, Front. Bioeng. Biotechnol. 2018, 6. PMC5816578 29487848
  116. [122]K. A. Potter‐Baker, J. K. Nguyen, K. M. Kovach, M. M. Gitomer, T. W. Srail, W. G. Stewart, J. L. Skousen, J. R. Capadona, J. Mater. Chem. B 2014, 2, 2248. 25132966 PMC4131700
  117. [123]D. F. Moyano, M. Goldsmith, D. J. Solfiell, D. Landesman‐Milo, O. R. Miranda, D. Peer, V. M. Rotello, J. Am. Chem. Soc. 2012, 134, 3965. 22339432 PMC3296893
  118. [124]P. Thevenot, W. Hu, L. Tang, Curr. Top. Med. Chem. 2008, 8, 4. PMC3230929 18393890
  119. [125]B. K. Leung, R. Biran, C. J. Underwood, P. A. Tresco, Biomaterials 2008, 29, 3289. 18485471
  120. [126]A. Higuchi, K. Shirano, M. Harashima, B. O. Yoon, M. Hara, M. Hattori, K. Imamura, Biomaterials 2002, 23, 2659. 12059015
  121. [127]D. E. MacDonald, N. Deo, B. Markovic, M. Stranick, P. Somasundaran, Biomaterials 2002, 23, 1269. 11791930
  122. [128]H. Hess, V. Vogel, Rev. Mol. Biotechnol. 2001, 82, 67. 11999714
  123. [129]R. Maitra, C. C. Clement, G. M. Crisi, N. Cobelli, L. Santambrogio, PLoS One 2008, 3, e2438. 18560588 PMC2413007
  124. [130]J. N. Barbosa, P. Madureira, M. A. Barbosa, A. P. Águas, J. Biomed. Mater. Res. A 2006, 76A, 737. 16331651
  125. [131]S. Kamath, D. Bhattacharyya, C. Padukudru, R. B. Timmons, L. Tang, J. Biomed. Mater. Res. A 2008, 86A, 617. PMC3230934 18022841
  126. [132]L. Tang, Y. Wu, R. B. Timmons, J. Biomed. Mater. Res. 1998, 42, 156. 9740018
  127. [133]K. M. Evans‐Nguyen, L. R. Tolles, O. V. Gorkun, S. T. Lord, M. H. Schoenfisch, Biochemistry 2005, 44, 15561. 16300405
  128. [134]A. Golabchi, B. Wu, B. Cao, C. J. Bettinger, X. T. Cui, Biomaterials 2019, 225, 119519. 31600673 PMC6896321
  129. [135]C.‐H. Chen, C.‐T. Lin, W.‐L. Hsu, Y.‐C. Chang, S.‐R. Yeh, L.‐J. Li, D.‐J. Yao, Nanomed. Nanotechnol. Biol. Med. 2013, 9, 5.
  130. [136]S. N. Christo, K. R. Diener, A. Bachhuka, K. Vasilev, J. D. Hayball, Biomed Res. Int. 2015, 2015, 342304. 26247017 PMC4515263
  131. [137]T. G. Schuhmann, T. Zhou, G. Hong, J. M. Lee, T.‐M. Fu, H.‐G. Park, C. M. Lieber, J. Vis. Exp. 2018, 137. PMC6126522 30080192
  132. [138]A. Ghazavi, J. Maeng, M. Black, S. Salvi, S. F. Cogan, J. Neural Eng. 2020, 17, 016022. 31665712 PMC7376958
  133. [139]A. S. Pranti, A. Schander, A. Bödecker, W. Lang, Sens. Actuators, B 2018, 275, 382.
  134. [140]J. J. Jun, N. A. Steinmetz, T. D. Harris, Nature 2017, 551, 232. 29120427 PMC5955206
  135. [141]G. Hong, C. M. Lieber, Nat. Rev. Neurosci. 2019, 20, 6. 30992558
  136. [142]A. Tooker, V. Tolosa, K. G. Shah, H. Sheth, S. Felix, T. Delima, S. Pannu, in 2012 Annual Int. Conf. of the IEEE Engineering in Medicine and Biology Society, IEEE, Piscataway, NJ 2012. 23367296
  137. [143]K. Scholten, C. E. Larson, H. Xu, D. Song, E. Meng, J. Microelectromech. Syst. 2020, 29, 1054. 33746477 PMC7978043
  138. [144]H.‐Y. Lai, L.‐D. Liao, C.‐T. Lin, J.‐H. Hsu, X. He, Y.‐Y. Chen, J.‐Y. Chang, H.‐F. Chen, S. Tsang, Y.‐Y. I. Shih, J. Neural Eng. 2012, 9, 3. 22488106
  139. [145]D. R. Merrill, M. Bikson, J. G. Jefferys, J. Neurosci. Methods 2005, 141, 171. 15661300
  140. [146]R. V. Shannon, IEEE Trans. Biomed. Eng. 1992, 39, 424. 1592409
  141. [147]S. Nimbalkar, E. Castagnola, A. Balasubramani, A. Scarpellini, S. Samejima, A. Khorasani, A. Boissenin, S. Thongpang, C. Moritz, S. Kassegne, Sci. Rep. 2018, 8, 6958. 29725133 PMC5934383
  142. [148]J. Rozman, I. MilosIev, M. Jenko, J. Med. Eng. Technol. 2000, 24, 123. 11036579
  143. [149]R. L. White, T. J. Gross, IEEE Trans. Biomed. Eng. 1974, BME‐21, 487.
  144. [150]T. M. Fu, G. S. Hong, R. D. Viveros, T. Zhou, C. M. Lieber, Proc. Natl. Acad. Sci. USA 2017, 114, 47. PMC5703340 29109247
  145. [151]S. Shim, H.‐Y. Park, G. J. Choi, H.‐C. Shin, S. J. Kim, ACS Omega 2019, 4, 2590.
  146. [152]S. Rezaei, Y. Xu, S. Pang, PLoS One 2019, 14, 7. PMC6655783 31339963
  147. [153]Z. Xiang, S.‐C. Yen, N. Xue, T. Sun, W. M. Tsang, S. Zhang, L.‐D. Liao, N. V. Thakor, C. Lee, J. Micromech. Microeng. 2014, 24, 065015.
  148. [154]P. L. Drake, K. J. Hazelwood, Ann. Occup. Hyg. 2005, 49, 7. 15964881
  149. [155]G. Buzsáki, C. A. Anastassiou, C. Koch, Nat. Rev. Neurosci. 2012, 13, 407. 22595786 PMC4907333
  150. [157]M. D. Ferro, N. A. Melosh, Adv. Funct. Mater. 2018, 28, 1704335.
  151. [158]J. Gimsa, B. Habel, U. Schreiber, U. van Rienen, U. Strauss, U. Gimsa, J. Neurosci. Methods 2005, 142, 251. 15698665
  152. [159]T. Zhou, G. Hong, T.‐M. Fu, X. Yang, T. G. Schuhmann, R. D. Viveros, C. M. Lieber, Proc. Natl. Acad. Sci. USA 2017, 114, 23. PMC5468665 28533392
  153. [160]E. Tóth, D. Fabó, L. Entz, I. Ulbert, L. Erőss, J. Neurosci. Methods 2016, 260, 261. 26453987
  154. [161]H. R. Joo, J. L. Fan, S. Chen, J. A. Pebbles, H. Liang, J. E. Chung, A. M. Yorita, A. Tooker, V. Tolosa, C. Geaghan‐Breiner, D. Roumis, D. Liu, R. Haque, L. Frank, J. Neural Eng. 2019, 16, 066021. 31216526 PMC7036288
  155. [162]Y. Wu, J. Zou, S. Huo, H. Lu, Y. Kong, T. Chen, W. Wu, J. Xu, Nanosci. Nanotechnol. 2015, 15, 8. 26369142
  156. [163]F. Awaja, S. Zhang, M. Tripathi, A. Nikiforov, N. Pugno, Prog. Mater. Sci. 2016, 83, 536.
  157. [164]T. D. Y. Kozai, K. Catt, X. Li, Z. V. Gugel, V. T. Olafsson, A. L. Vazquez, X. T. Cui, Biomaterials 2015, 37, 25. 25453935 PMC4312222
  158. [166]M. Asmah, in 2016 IEEE 37th Int. Electronics Manufacturing Technology (IEMT) & 18th Electronics Materials and Packaging, IEEE, Piscataway, NJ 2016.
  159. [167]B. S. Elkin, E. U. Azeloglu, K. D. Costa, B. Morrison Iii, J. Neurotrauma 2007, 24, 812. 17518536
  160. [168]A. Gefen, N. Gefen, Q. Zhu, R. Raghupathi, S. S. Marguiles, J. Neurotrauma 2003, 20, 1163. 14651804
  161. [169]S. A. Kruse, G. H. Rose, K. J. Glaser, A. Manduca, J. P. Felmlee, C. R. Jack, R. L. Ehman, NeuroImage 2008, 39, 231. 17913514 PMC2387120
  162. [170]S. W. Moore, M. P. Sheetz, Dev. Neurobiol. 2011, 71, 11. PMC3307797 21739614
  163. [171]H. Sekiguchi, H. Yasunaga, K. Tsuchiyama, R. Nitta, Electron. Lett. 2019, 55, 619.
  164. [172]C. Chen, W. Yao, W. Sun, T. Guo, H. Lv, X. Wang, H. Ying, Y. Wang, P. Wang, Int. J. Biol. Macromol. 2019, 122, 1. 30219514
  165. [173]M. HajjHassan, V. Chodavarapu, S. Musallam, Sensors 2008, 8, 6704. 27873894 PMC3707475
  166. [174]W. H. Pei, H. Zhao, S. S. Zhao, X. L. Fang, S. Y. Chen, Q. Gui, R. Y. Tang, Y. F. Chen, B. Hong, X. R. Gao, H. D. Chen, J. Micromech. Microeng. 2014, 24, 095015.
  167. [175]Z. Fekete, Sens. Actuators, B 2015, 215, 300.
  168. [176]K. Na, Z. J. Sperry, J. Lu, M. Vöröslakos, S. S. Parizi, T. M. Bruns, E. Yoon, J. P. Seymour, Microsyst. Nanoeng. 2020, 6, 37. 32528723 PMC7261651
  169. [177]G. S. Hong, R. D. Viveros, T. J. Zwang, X. Yang, C. M. Lieber, Biochemistry 2018, 57, 27. PMC6039269 29529359
  170. [178]M.‐c. Lo, S. Wang, S. Singh, V. B. Damodaran, I. Ahmed, K. Coffey, D. Barker, K. Saste, K. Kals, H. M. Kaplan, J. Neural Eng. 2018, 15, 3. PMC7381127 29485103
  171. [179]H. Shin, Y. Son, U. Chae, J. Kim, N. Choi, H. J. Lee, J. Woo, Y. Cho, S. H. Yang, C. J. Lee, I.‐J. Cho, Nat. Commun. 2019, 10, 3777. 31439845 PMC6706395
  172. [180]M. J. Leccardi, P. Vagni, D. Ghezzi, J. Neural Eng. 2019, 16. 30215607
  173. [181]T. M. Fu, G. S. Hong, T. Zhou, T. G. Schuhmann, R. D. Viveros, C. M. Lieber, Nat. Methods 2016, 13, 875. 27571550
  174. [182]L. Luan, X. L. Wei, Z. T. Zhao, J. J. Siegel, O. Potnis, C. A. Tuppen, S. Q. Lin, S. Kazmi, R. A. Fowler, S. Holloway, A. K. Dunn, R. A. Chitwood, C. Xie, Sci. Adv. 2017, 3, e1601966. 28246640 PMC5310823
  175. [183]C. Bezzina, L. Verret, C. Juan, J. Remaud, H. Halley, C. Rampon, L. Dahan, PLoS One 2015, 10, e0119910. 25768013 PMC4358928
  176. [184]A. L. Benabid, Curr. Opin. Neurobiol. 2003, 13, 696. 14662371
  177. [185]S. B. Goncalves, A. M. Loureiro, H. C. Fernandes, S. Pimenta, J. F. Ribeiro, J. H. Correia, J. Microelectromech. Syst. 2018, 27, 1097.
  178. [186]G. Buzsaki, Nat. Neurosci. 2004, 7, 446. 15114356
  179. [187]W. G. Song, A. Ramakrishnan, U. I. Udoekwere, S. F. Giszter, IEEE Trans. Biomed. Eng. 2009, 56, 2712. 19605313 PMC2883457
  180. [188]W. G. Song, S. F. Giszter, J. Neurosci. 2011, 31, 8. PMC3243498 21414932
  181. [189]M. Velliste, S. Perel, M. C. Spalding, A. S. Whitford, A. B. Schwartz, Nature 2008, 453, 1098. 18509337
  182. [190]M. Capogrosso, T. Milekovic, D. Borton, F. Wagner, E. M. Moraud, J. B. Mignardot, N. Buse, J. Gandar, Q. Barraud, D. Xing, E. Rey, S. Duis, J. Z. Yang, W. K. D. Ko, Q. Li, P. Detemple, T. Denison, S. Micera, E. Bezard, J. Bloch, G. Courtine, Nature 2016, 539, 284. 27830790 PMC5108412
  183. [191]J. D. Simeral, S. P. Kim, M. J. Black, J. P. Donoghue, L. R. Hochberg, J. Neural Eng. 2011, 8, 025027. 21436513 PMC3715131
  184. [192]P. K. Campbell, K. E. Jones, R. J. Huber, K. W. Horch, R. A. Normann, IEEE Trans. Biomed. Eng. 1991, 38, 758. 1937509
  185. [193]S. B. Frost, C. L. Dunham, S. Barbay, D. Krizsan‐Agbas, M. K. Winter, D. J. Guggenmos, R. J. Nudo, J. Neurotrauma 2015, 32, 1666. 26406381 PMC4638198
  186. [194]D. J. Guggenmos, M. Azin, S. Barbay, J. D. Mahnken, C. Dunham, P. Mohseni, R. J. Nudo, Proc. Natl. Acad. Sci. USA 2013, 110, 21177. 24324155 PMC3876197
  187. [195]K. Kampasi, D. F. English, J. Seymour, E. Stark, S. McKenzie, M. Vöröslakos, G. Buzsáki, K. D. Wise, E. Yoon, Microsyst. Nanoeng. 2018, 4, 10. 30766759 PMC6220186
  188. [196]A. Canales, X. T. Jia, U. P. Froriep, R. A. Koppes, C. M. Tringides, J. Selvidge, C. Lu, C. Hou, L. Wei, Y. Fink, P. Anikeeva, Nat. Biotechnol. 2015, 33, 277. 25599177
  189. [197]B. Rubehn, S. B. E. Wolff, P. Tovote, A. Luthi, T. Stieglitz, Lab Chip 2013, 13, 579. 23306183
  190. [198]I. R. Minev, P. Musienko, A. Hirsch, Q. Barraud, N. Wenger, E. M. Moraud, J. Gandar, M. Capogrosso, T. Milekovic, L. Asboth, R. F. Torres, N. Vachicouras, Q. H. Liu, N. Pavlova, S. Duis, A. Larmagnac, J. Voros, S. Micera, Z. G. Suo, G. Courtine, S. P. Lacour, Science 2015, 347, 159. 25574019
  191. [199]S. Il Park, D. S. Brenner, G. Shin, C. D. Morgan, B. A. Copits, H. U. Chung, M. Y. Pullen, K. N. Noh, S. Davidson, S. J. Oh, J. Yoon, K. I. Jang, V. K. Samineni, M. Norman, J. G. Grajales‐Reyes, S. K. Vogt, S. S. Sundaram, K. M. Wilson, J. S. Ha, R. X. Xu, T. S. Pan, T. I. Kim, Y. G. Huang, M. C. Montana, J. P. Golden, M. R. Bruchas, R. W. Gereau, J. A. Rogers, Nat. Biotechnol. 2015, 33, 12. 26551059 PMC4880021
  192. [200]S. Lachhman, C. A. Zorman, W. H. Ko, in IEEE Engineering in Medicine and Biology Society, Piscataway, NJ 2012. PMC3561723 23366225
  193. [201]S. K. Kelly, D. B. Shire, J. Chen, P. Doyle, M. D. Gingerich, S. F. Cogan, W. A. Drohan, S. Behan, L. Theogarajan, J. L. Wyatt, J. F. Rizzo, III, IEEE Trans. Biomed. Eng. 2011, 58, 11. PMC4876049 21859595
  194. [202]T. I. Kim, J. G. McCall, Y. H. Jung, X. Huang, E. R. Siuda, Y. H. Li, J. Z. Song, Y. M. Song, H. A. Pao, R. H. Kim, C. F. Lu, S. D. Lee, I. S. Song, G. Shin, R. Al‐Hasani, S. Kim, M. P. Tan, Y. G. Huang, F. G. Omenetto, J. A. Rogers, M. R. Bruchas, Science 2013, 340, 6129. PMC3769938 23580530
  195. [203]A. Williamson, M. Ferro, P. Leleux, E. Ismailova, A. Kaszas, T. Doublet, P. Quilichini, J. Rivnay, B. Rozsa, G. Katona, C. Bernard, G. G. Malliaras, Adv. Mater. 2015, 27, 30. 26129730
  196. [204]D. Khodagholy, T. Doublet, P. Quilichini, M. Gurfinkel, P. Leleux, A. Ghestem, E. Ismailova, T. Herve, S. Sanaur, C. Bernard, G. G. Malliaras, Nat. Commun. 2013, 4, 1. PMC3615373 23481383
  197. [205]D. Khodagholy, J. N. Gelinas, T. Thesen, W. Doyle, O. Devinsky, G. G. Malliaras, G. Buzsaki, Nat. Neurosci. 2015, 18, 310. 25531570 PMC4308485
  198. [206]J. Jeong, S. H. Bae, J.‐M. Seo, H. Chung, S. J. Kim, J. Neural Eng. 2016, 13, 2. 26905477
  199. [207]H. Yang, A. Buguin, J.‐M. Taulemesse, K. Kaneko, S. Méry, A. Bergeret, P. Keller, J. Am. Chem. Soc. 2009, 131, 41. 19778041
  200. [208]J. Maeng, R. T. Rihani, M. Javed, J. S. Rajput, H. Kim, I. G. Bouton, T. A. Criss, J. J. Pancrazio, B. J. Black, T. H. Ware, J. Mater. Chem. B 2020. 32315020

200 of 377 shown

Cited by

Sorted by citations

Related

Authors
McGlynn, E., Nabaei, V., Ren, E., Galeote‐Checa, G., Das, R., Curia, G., & Heidari, H.
Affiliations
  • University of Glasgow (GB)
  • University of Modena and Reggio Emilia (IT)
  • Microelectronics Lab James Watt School of Engineering University of Glasgow Glasgow G12 8QQ United Kingdom
Corresponding author
Heidari, Hadi
ORCID
Venue
Advanced Science
Publisher
Wiley
Published
2021-03-09
Volume
8
Issue
10
Pages
2002693-2002693
ISSN
2198-3844 (ISSN-L)
DOI
10.1002/advs.202002693
PMC
PMC8132070
OpenAlex
W3134520991
Cited by
115
References
377
Citations by year
2026: 17 · 2025: 25 · 2024: 26 · 2023: 17 · 2022: 21 · 2021: 9
FWCI
2.76
Type
journal article
Language
en
Update notices
correction (2021-07-21)
Open access
Licence
Locations
  • Advanced Science (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion, cc-by-sa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
  • IRIS UNIMORE (University of Modena and Reggio Emilia) (submittedVersion, cc-by)
Funders
H2020 Future and Emerging Technologies (824164)
Topics
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neural Engineering
  • Physical Sciences › Engineering › Biomedical Engineering › Analog and Mixed-Signal Circuit Design
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Undergraduate Neuroscience Education and Research
Keywords
wireless neural interface, deep brain stimulation alternative, foreign body reaction, biomaterials, wireless power transfer, neurological disorders
MeSH terms
Animals, Brain, Equipment Design, Humans, Microelectrodes, Nervous System Diseases, Neurosciences, Deep Brain Stimulation, Wireless Technology

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review