Cited by 180Human Mobility and Location-Based AnalysisMental Health Research TopicsBipolar Disorder and Treatment

Detecting Bipolar Depression From Geographic Location Data

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Palmius, N., Tsanas, A., Saunders, K. E. A., Bilderbeck, A. C., Geddes, J. R., Goodwin, G. M., De Vos, M.·2017·IEEE Transactions on Biomedical Engineering

Abstract

OBJECTIVE: This paper aims to identify periods of depression using geolocation movements recorded from mobile phones in a prospective community study of individuals with bipolar disorder (BD). METHODS: ). Recorded location data were preprocessed by detecting and removing imprecise data points and features were extracted to assess the level and regularity of geographic movements of the participant. A subset of features were selected using a wrapper feature selection method and presented to 1) a linear regression model and a quadratic generalized linear model with a logistic link function for questionnaire score estimation; and 2) a quadratic discriminant analysis classifier for depression detection in BD participants based on their questionnaire responses. R esults: HC participants did not report depressive symptoms and their features showed similar distributions to nondepressed BD participants. Questionnaire score estimation using geolocation-derived features from BD participants demonstrated an optimal mean absolute error rate of 3.73, while depression detection demonstrated an optimal (median ± IQR) [Formula: see text] score of 0.857 ± 0.022 using five features (classification accuracy: 0.849 ± 0.016; sensitivity: 0.839 ± 0.014; specificity: 0.872 ± 0.047). CONCLUSION: These results demonstrate a strong link between geographic movements and depression in bipolar disorder. S ignificance: To our knowledge, this is the first community study of passively recorded objective markers of depression in bipolar disorder of this scale. The techniques could help individuals monitor their depression and enable healthcare providers to detect those in need of care or treatment.

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  1. [40]Hastie T Tibshirani R Friedman J The Elements of Statistical Learning: Data Mining, Inference, and Prediction (Springer Series in Statistics) 2nd ed New York, NY, USA Springer-Verlag 2009

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Authors
Palmius, N., Tsanas, A., Saunders, K. E. A., Bilderbeck, A. C., Geddes, J. R., Goodwin, G. M., & De Vos, M.
Affiliations
University of Oxford (GB)
Venue
IEEE Transactions on Biomedical Engineering
Published
2017-08
Volume
64
Issue
8
Pages
1761-1771
ISSN
  • 0018-9294 (ISSN-L)
  • 1558-2531
OpenAlex
W2538898996
Cited by
180
References
40
Citations by year
2026: 8 · 2025: 15 · 2024: 16 · 2023: 24 · 2022: 22 · 2021: 16 · 2020: 39 · 2019: 14 · 2018: 16 · 2017: 10
FWCI
21.86
Type
journal article
Language
en
Open access
Locations
  • IEEE Transactions on Biomedical Engineering (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion, cc-by)
  • PubMed Central (acceptedVersion, cc-by)
  • Edinburgh Research Explorer (University of Edinburgh) (submittedVersion, cc-by)
Funders
  • EPSRC
  • Wellcome Trust Centre (098461/Z/12/Z)
  • Sleep, Circadian Rhythms & Neuroscience Institute (102616/Z)
  • RCUK Digital Economy Programme (EP/G036861/1)
Topics
  • Social Sciences › Transportation › Human Mobility and Location-Based Analysis
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Mental Health Research Topics
  • Health Sciences › Medicine › Psychiatry and Mental health › Bipolar Disorder and Treatment
Keywords
bipolar depression, bipolar disorder, geolocation data, depression detection, passive monitoring, quadratic discriminant analysis, community-based research
MeSH terms
Adult, Bipolar Disorder, Female, Humans, Male, Middle Aged, Patient Identification Systems, Sensitivity and Specificity, Reproducibility of Results, Geographic Information Systems, Cell Phone, Actigraphy, Remote Sensing Technology

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