A Robust Fusion Model for Estimating Respiratory Rate From Photoplethysmography and Electrocardiography
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OBJECTIVE: Respiratory rate (RR) estimation algorithms based on the photoplethymogram (PPG) and electrocardiogram (ECG) lack clinical robustness. This is because the PPG and ECG respiratory modulations are dependent on patient physiology, regardless of general signal quality. The present work describes an RR estimation algorithm using respiratory quality indices (RQIs) that assess the presence or absence of the PPG- and ECG-derived respiratory modulations. METHODS: Six respiratory waveforms are derived from the amplitude modulation, frequency modulation, and baseline wander of the PPG and ECG. The respiratory quality of each modulation is assessed by using RQIs based on the fast Fourier transform, autoregression, and autocorrelation. The individual RQIs are fused to obtain a single RQI per modulation per time window. Based on a tunable threshold, the RQIs are used to discard poor modulations and weight the remaining modulations to provide a single RR estimation per time window. RESULTS: The proposed method was tested on two independent datasets and found that using a conservative threshold, the mean absolute error was 0.71 $\pm$ 0.89 and 3.12 $\pm$ 4.39 brpm while discarding only 1.3% and 23.2% of all time windows, for each dataset, respectively. CONCLUSION: These errors are either better than or comparable to current methods, and the number of windows discarded is far lower demonstrating improved robustness. SIGNIFICANCE: This work describes a novel preprocessing algorithm that can be implemented in conjunction with other RR estimation techniques to improve robustness by specifically considering the quality of the respiratory information.
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A key challenge for RR algorithms is to make them robust to signal artifact and only output values associated with a high degree of confidence, particularly when used with wearable data.
“A key challenge is to make algorithms robust to signal artifact and only output values associated with a high degree of confidence”
From Wearable Photoplethysmography for Cardiovascular Monitoring (2022) · cites this paper as [89]
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Respiratory Signal Extraction from ECG Signal
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- Authors
- Birrenkott, D. A., Pimentel, M. A. F., Watkinson, P. J., & Clifton, D. A.
- Affiliations
- University of Oxford (GB)
- Oxford University Hospitals NHS Trust (GB)
- Venue
- IEEE Transactions on Biomedical Engineering
- Published
- 2018-09
- Volume
- 65
- Issue
- 9
- Pages
- 2033-2041
- ISSN
- 0018-9294 (ISSN-L)
- 1558-2531
- OpenAlex
- W2776923905
- Cited by
- 71
- References
- 29
- Citations by year
- 2026: 6 · 2025: 6 · 2024: 7 · 2023: 8 · 2022: 11 · 2021: 9 · 2020: 13 · 2019: 8 · 2018: 2 · 2017: 1
- FWCI
- 2.95
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- IEEE Transactions on Biomedical Engineering (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Funders
- Wellcome Trust (WT 088877/Z/09/Z)
- The Rhodes Trust
- Topics
- Physical Sciences › Engineering › Biomedical Engineering › Non-Invasive Vital Sign Monitoring
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › ECG Monitoring and Analysis
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Keywords
- respiratory rate estimation, photoplethysmography, electrocardiogram, multimodal signal fusion, amplitude modulation, frequency modulation, baseline wander, signal quality assessment, autoregression, autocorrelation, fast Fourier transform, robustness
- MeSH terms
- Algorithms, Electrocardiography, Humans, Signal Processing, Computer-Assisted, Photoplethysmography, Respiratory Rate
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