The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Pandemic lineages of extraintestinal pathogenic Escherichia coli
Open accessAbstract
Pathogenic Escherichia coli strains cause a wide variety of intestinal and extraintestinal infections. The widespread geographical clonal dissemination of intestinal pathogenic E. coli strains, such as E. coli O157:H7, is well recognized, and its spread is most often attributed to contaminated food products. On the other hand, the clonal dissemination of extraintestinal pathogenic E. coli (ExPEC) strains is also recognized, but the mechanism of their spread is not well explained. Here, I describe major pandemic clonal lineages of ExPEC based on multilocus sequence typing (MLST), and discuss possible reasons for their global dissemination. These lineages include sequence type (ST)131, ST393, ST69, ST95, and ST73, which are all associated with both community-onset and healthcare-associated infections, in particular urinary tract infections and bloodstream infections. As with many other types of drug-resistant Gram-negative and Gram-positive bacterial infections, drug-resistant ExPEC infections are recognized to be caused by a limited set of clonal lineages. However, reported observations on these major pandemic lineages suggest that the resistance phenotype is not necessarily the determinant of their clonal dissemination. Both epidemiological factors and their intrinsic biological 'fitness' are likely to contribute. An important public health and clinical concern is that pandemicity itself may be a determinant of progressive drug resistance acquisition by clonal lineages. New research is urgently needed to better understand the epidemiological and biological causes of ExPEC pandemicity.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Indeed, we identified specific STs linked to neonatal infections, such as E. coli ST119347, ST73 and ST9547,48, and K. pneumoniae ST43249 strains, which are typically drug-resistant strains and of clinical significance.”
From Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants. (2025) · cites this paper as [48]
Citations
Cites
Tenover, F. C., Arbeit, R. D., Goering, R. V., Mickelsen, P. A., Murray, B. E., Persing, D. H., & Swaminathan, B. (1995) · Journal of Clinical Microbiology · doi:10.1128/jcm.33.9.2233-2239.1995 · Cited by 8,203
Diarrheagenic Escherichia coli
Nataro, J. P., & Kaper, J. B. (1998) · Clinical Microbiology Reviews · doi:10.1128/cmr.11.1.142 · Cited by 5,109
Sex and virulence in Escherichia coli : an evolutionary perspective
Wirth, T., Falush, D., Lan, R., Colles, F. M., Mensa, P., Wieler, L. H., Karch, H., Reeves, P. R., Maiden, M. C. J., Ochman, H., et al. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05172.x · Cited by 2,075
Extended-spectrum β-lactamase-producing Enterobacteriaceae: an emerging public-health concern
Pitout, J. D. D., & Laupland, K. B. (2008) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(08)70041-0 · Cited by 2,068
Johnson, J. R., & Stell, A. L. (2000) · The Journal of Infectious Diseases · doi:10.1086/315217 · Cited by 1,269
Epidemic Profile of Shiga-Toxin–Producing Escherichia coli O104:H4 Outbreak in Germany
Frank, C., Werber, D., Cramer, J. P., Askar, M., Faber, M., an der Heiden, M., Bernard, H., Fruth, A., Prager, R., Spode, A., et al. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1106483 · Cited by 1,139
Woodford, N., Turton, J. F., & Livermore, D. M. (2011) · FEMS Microbiology Reviews · doi:10.1111/j.1574-6976.2011.00268.x · Cited by 881
OUTCOME FOR INFANTS OF VERY LOW BIRTHWEIGHT: SURVEY OF WORLD LITERATURE
Stewart, A. C. (1981) · The Lancet · doi:10.1016/s0140-6736(81)92198-x · Cited by 835
Intercontinental emergence of Escherichia coli clone O25:H4-ST131 producing CTX-M-15
Nicolas-Chanoine, M.-H., Blanco, J., Leflon‐Guibout, V., Demarty, R., Alonso, M. P., Caniça, M., Park, Y. J., Lavigne, J., Pitout, J. D. D., & Johnson, J. R. (2007) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkm464 · Cited by 815
Increasing prevalence of ESBL-producing Enterobacteriaceae in Europe
Coque, T. M., Baquero, F., & Cantón, R. (2008) · Eurosurveillance · doi:10.2807/ese.13.47.19044-en · Cited by 808
Cited by
Sorted by citations
Items 401–413 of 413
Mabandza, B. D. B. (2024) · theses.fr (ABES) · doi:10.70675/9ae1dd65z81c2z4558z93e5zf2b97f4efecf
Establishment of a Rapid Escherichia coli Detection Method Based on MIRA-PfAgo
Chen, X., Liu, Y., Wang, J., Dai, Y., Shen, X., Pan, X., & Yin, D. (2026) · Biosensors · doi:10.3390/bios16050248
Fuerte-Stone, J., Ghali, J., Valaitis, S. R., & Mimee, M. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.05.11.724322
Gao, L., Wu, J. Y., Huang, X. R., Lin, X. Y., Lin, D. T., Zhu, Y., Lin, X.-Z., & Lai, J. D. (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1855839
Molecular Epidemiology of blaNDM-Positive E. coli in Jiangsu Chicken Production Chain
MengJun, T., Zhou, Q., Zhang, X., Jia, X., Tang, X., Yang, X., & Gao, Y. (2026) · Agriculture · doi:10.3390/agriculture16131438
Prince, R. J. D., Bogati, R., Lytle, T., Silva, A. C., LeBaron, R. A., Sorge, T., Olson, M. A., Wilson, E., & Erickson, D. L. (2026) · mSphere · doi:10.1128/msphere.00237-26
Souza, B. D. V. L., Solveira, G., de Souza, G. F. R., Orsi, H., de Lira, D. R. P., Fernandes, I. D. A., Ferreira, A. M., Mondelli, A. L., Sacchi, C. T., Campos, K. R., et al. (2026) · Brazilian Journal of Microbiology · doi:10.1007/s42770-026-02018-3
Vorimore, F., Tran, M.-L., Jaudou, S., Fach, P., & Delannoy, S. (2026) · Microbial Genomics · doi:10.1099/mgen.0.001794
Popa, L.-I., Dinu, S., Cristea, D., Ghiță, A., Ionescu, G., & Oprea, M. M. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1891649
Environmental monitoring for antimicrobial resistance in a metropolitan watershed
Holcomb, D., Cantrell, M. E., Feistel, D. J., Meyer, M., Sterling, J., Chen, J. C., Krishnan, K., Im, S. B., Folster, J. P., Kim, J., et al. (2026) · Journal of Water and Health · doi:10.2166/wh.2026.219
Lignieres, G., Bidet, P., Birgy, A., La, K., Geslain, G., Denamur, É., Béchet, S., Cotto, O., Blanquart, F., Thollot, F., et al. (2026) · International Journal of Medical Microbiology · doi:10.1016/j.ijmm.2026.151734
Nyondo, F. C. (2026) · Access Microbiology · doi:10.1099/acmi.0.001165.v3
Aurich, S., Pirolo, M., Giarratana, L. R., Nielsen, K. L., Damborg, P., & Guardabassi, L. (2026) · Comparative Immunology Microbiology and Infectious Diseases · doi:10.1016/j.cimid.2026.102536
Metadata
- Authors
- Riley, L. W.
- Affiliations
- University of California, Berkeley (US)
- Corresponding author
- Riley, L.W.
- ORCID
- Riley, L.W.
- Venue
- Clinical Microbiology and Infection
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 20
- Issue
- 5
- Pages
- 380-390
- ISSN
- 1198-743X (ISSN-L)
- OpenAlex
- W2027836512
- Cited by
- 412
- References
- 115
- Citations by year
- 2026: 18 · 2025: 43 · 2024: 42 · 2023: 46 · 2022: 47 · 2021: 37 · 2020: 57 · 2019: 36 · 2018: 22 · 2017: 24 · 2016: 17 · 2015: 19 · 2014: 4
- FWCI
- 2.79
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Clinical Microbiology and Infection (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Immunology and Microbiology › Microbiology › Escherichia coli research studies
- Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
- Health Sciences › Medicine › Urology › Urinary Tract Infections Management
- Keywords
- extraintestinal pathogenic Escherichia coli, multilocus sequence typing, ST131, ST69, ST95, ST73, antimicrobial resistance, urinary tract infection, bloodstream infection, community-onset infection, nosocomial infections, clonal spread, bacterial fitness
- MeSH terms
- Escherichia coli, Escherichia coli Infections, Humans, Virulence, Bacterial Typing Techniques, Molecular Epidemiology, Cell Lineage, Drug Resistance, Bacterial, Pandemics, Multilocus Sequence Typing
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
