Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants

Kiu, Raymond; Darby, Elizabeth M.; Alcon-Giner, Cristina; Acuna-Gonzalez, Antia; Camargo, Anny; Lamberte, Lisa E.; Phillips, Sarah; Sim, Kathleen; Shaw, Alexander G.; Clarke, Paul; van Schaik, Willem; Kroll, J. Simon; Hall, Lindsay J.

doi:10.1038/s41467-025-62584-2

Impact of early life antibiotic and probiotic treatment on gut microbiome and resistome of very-low-birth-weight preterm infants

Preterm infants ( Bifidobacterium strains) may help restore a healthy gut microbiota. In this study, we investigated the effects of probiotics and antibiotics on the gut microbiome and resistome in two unique cohorts of 34 very-low-birth-weight, human-milk-fed preterm infants - one of which recei…