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Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: A Review

Carbonell‐Capella, Juana M., Buniowska, Magdalena, Barba, Francisco J., Esteve, María J., Frígola, Ana.·2014·Comprehensive Reviews in Food Science and Food Safety

Abstract

Determination of bioactive compounds content directly from foodstuff is not enough for the prediction of potential in vivo effects, as metabolites reaching the blood system may be different from the original compounds found in food, as a result of an intensive metabolism that takes place during absorption. Nutritional efficacy of food products may be ensured by the determination of bioaccessibility, which provides valuable information in order to select the appropriate dosage and source of food matrices. However, between all the methods available, there is a need to establish the best approach for the assessment of specific compounds. Comparison between in vivo and in vitro procedures used to determine bioaccessibility and bioavailability is carried out, taking into account the strengths and limitations of each experimental technique, along with an intensive description of actual approaches applied to assess bioaccessibility of bioactive compounds. Applications of these methods for specific bioactive compound's bioaccessibility or bioavailability are also discussed, considering studies regarding the bioavailability of carotenoids, polyphenolic compounds, glucosinolates, vitamin E, and phytosterols.

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Metadata

Authors
Carbonell‐Capella, J. M., Buniowska, M., Barba, F. J., Esteve, M. J., & Frígola, A.
Venue
Comprehensive Reviews in Food Science and Food Safety
Publisher
Wiley
Published
2014-02-21
Volume
13
Issue
2
Pages
155-171
ISSN
1541-4337 (ISSN-L)
OpenAlex
W1842175440
Cited by
656
References
6
FWCI
18.55
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: A Review. https://app.cochat.ai/papers/10.1111/1541-4337.12049
The paper
Carbonell‐Capella, J. M., Buniowska, M., Barba, F. J., Esteve, M. J., & Frígola, A. (2014). Analytical Methods for Determining Bioavailability and Bioaccessibility of Bioactive Compounds from Fruits and Vegetables: A Review. Comprehensive Reviews in Food Science and Food Safety. https://doi.org/10.1111/1541-4337.12049

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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