Cited by 52Gut microbiota and healthProbiotics and Fermented FoodsMicrobial Metabolites in Food Biotechnology

Different Flavonoids Can Shape Unique Gut Microbiota Profile In Vitro

Huang, Jiacheng, Chen, Long, Xue, Bin, Liu, Qianyue, Ou, Shiyi, Wang, Yong, Peng, Xichun·2016·Journal of Food Science

Abstract

The impact of flavonoids has been discussed on the relative viability of bacterial groups in human microbiota. This study was aimed to compare the modulation of various flavonoids, including quercetin, catechin and puerarin, on gut microbiota culture in vitro, and analyze the interactions between bacterial species using fructo-oligosaccharide (FOS) as carbon source under the stress of flavonoids. Three plant flavonoids, quercetin, catechin, and puerarin, were added into multispecies culture to ferment for 24 h, respectively. The bacterial 16S rDNA amplicons were sequenced, and the composition of microbiota community was analyzed. The results revealed that the tested flavonoids, quercetin, catechin, and puerarin, presented different activities of regulating gut microbiota; flavonoid aglycones, but not glycosides, may inhibit growth of certain species. Quercetin and catechin shaped unique biological webs. Bifidobacterium spp. was the center of the biological web constructed in this study.

Integrity signals

Registry

Crossref · 10.1111/1750-3841.13411

Cites

37 of 37 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Huang, J., Chen, L., Xue, B., Liu, Q., Ou, S., Wang, Y., & Peng, X.
Affiliations
Jinan University (CN)
Corresponding author
Peng, Xichun
Venue
Journal of Food Science
Publisher
Wiley
Published
2016-07-29
Volume
81
Issue
9
Pages
H2273-9
ISSN
  • 0022-1147 (ISSN-L)
  • 1750-3841
OpenAlex
W2483302157
Cited by
52
References
37
Citations by year
2025: 2 · 2024: 6 · 2023: 4 · 2022: 12 · 2021: 7 · 2020: 5 · 2019: 5 · 2018: 8 · 2017: 3
FWCI
2.77
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Food Science (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • National Natural Science (31471589)
  • Central Universities (21615404)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Keywords
flavonoids, gut microbiota, quercetin, catechins, puerarin, fructooligosaccharides, bacterial community composition, bacterial interactions, Bifidobacterium, flavonoid aglycones, bacterial growth inhibition
MeSH terms
Gastrointestinal Microbiome, Bifidobacterium, Catechin, Flavonoids, Glycosides, Humans, Isoflavones, Oligosaccharides, Plant Extracts, Quercetin, RNA, Ribosomal, 16S, Microbiota

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review