Insight change in psychosis: relationship with neurocognition, social cognition, clinical symptoms and phase of illness
Open accessAbstract
Objective: Impaired insight is an important and prevalent symptom of psychosis. It remains unclear whether cognitive disturbances hamper improvements in insight. We investigated the neurocognitive, social cognitive, and clinical correlates of changes in insight. Method: One hundred and fifty‐four patients with a psychotic disorder were assessed at baseline (T0) and after three years (T3) with the Birchwood Insight Scale, the Positive And Negative Syndrome Scale, measures of neurocognition and social cognition. Linear regression analyses were conducted to examine to what extend neurocognition, social cognition, clinical symptoms and phase of illness could uniquely predict insight change. Subsequently, changes in these factors were related to insight change. Results: Better neurocognitive performance and fewer clinical symptoms at baseline explained insight improvements. The additional effect of clinical symptoms over and above the contribution of neurocognition was significant. Together, these factors explained 10% of the variance. Social cognition and phase of illness could not predict insight change. Changes in clinical symptoms, but not changes in neurocognitive performance were associated with insight change. Conclusion: Neurocognitive abilities may predict, in part, the development of insight in psychosis.
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Higher levels of symptoms at baseline predict lesser improvements in clinical insight over time.
“Higher levels of symptoms at baseline also predicted lesser improvements in clinical insight over time in individuals with psychosis 57 and schizophrenia 58 .”
From Insight in schizophrenia spectrum disorders: relationship with behavior, mood and perceived quality of life, underlying causes and emerging treatments (2018) · cites this paper as [57]
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- Authors
- Quee, P. J., van der Meer, L., Krabbendam, L., de Haan, L., Cahn, W., Wiersma, D., van Beveren, N., Pijnenborg, G. H. M., Mulder, C. L., Bruggeman, R., & Aleman, A.
- Affiliations
- University Medical Center Groningen (NL)
- Department of Rehabilitation Lentis Center for Mental Health Zuidlaren the Netherlands
- Faculty of Psychology and Education Vrije Universiteit Amsterdam Amsterdam the Netherlands
- Department of Psychiatry Academic Medical Center Amsterdam University of Amsterdam Amsterdam the Netherlands
- Utrecht University (NL)
- Delta Center for Mental Health Care Poortugaal the Netherlands
- University of Groningen (NL)
- Erasmus MC (NL)
- Corresponding author
- Quee, P. J.
- Venue
- Acta Psychiatrica Scandinavica
- Publisher
- Wiley
- Published
- 2013-04-18
- Volume
- 129
- Issue
- 2
- Pages
- 126-133
- ISSN
- 0001-690X (ISSN-L)
- 1600-0447
- OpenAlex
- W2148955207
- Cited by
- 29
- References
- 37
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 1 · 2022: 1 · 2021: 3 · 2020: 2 · 2019: 1 · 2018: 6 · 2017: 2 · 2016: 2 · 2015: 4 · 2014: 2 · 2013: 2
- FWCI
- 2.37
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Acta Psychiatrica Scandinavica (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- RePub (Erasmus University Rotterdam) (submittedVersion, other-oa)
- Pure Amsterdam UMC (submittedVersion)
- VU Research Portal (submittedVersion)
- University of Groningen research database (University of Groningen / Centre for Information Technology) (submittedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Arts and Humanities › Philosophy › Mental Health and Psychiatry
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- insight, psychosis, neurocognitive function, social cognition, clinical symptoms, PANSS, cognitive impairment
- MeSH terms
- Adult, Awareness, Cognition Disorders, Female, Humans, Male, Neuropsychological Tests, Psychotic Disorders, Schizophrenia, Schizophrenic Psychology, Self Concept, Severity of Illness Index, Social Behavior, Social Perception, Linear Models, Disease Progression, Young Adult
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