Cited by 72Smoking Behavior and CessationTuberculosis Research and EpidemiologySubstance Abuse Treatment and Outcomes

Efficacy of brief motivational interviewing on smoking cessation at tuberculosis clinics in T shwane, S outh A frica: a randomized controlled trial

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Louwagie, Goedele M. C., Okuyemi, Kolawole S., Ayo‐Yusuf, Olalekan A.·2014·Addiction

Abstract

Background and Aims: Tuberculosis (TB) patients who smoke risk adverse TB outcomes and other long‐term health effects of smoking. This study aimed to determine the efficacy of brief motivational interviewing by lay health‐care workers (LHCW s) in assisting TB patients to quit smoking. Design: Multi‐centre two‐group parallel individual randomized controlled trial. Setting: Six primary care tuberculosis clinics in a S outh A frican township. Participants: Newly diagnosed adult TB patients identified as current smokers were randomized to brief motivational interviewing by a LHCW (intervention group, n = 205) or brief smoking cessation advice from a TB nurse (control group, n = 204). Measurements: The primary outcome was self‐reported sustained 6‐month smoking abstinence. Exhaled carbon monoxide (CO) testing was offered to about half the participants. Secondary outcomes were sustained abstinence at 3 months; 7‐day point prevalence abstinence at 1, 3 and 6 months; and quit attempts. Allocation was concealed. Primary analysis relied on intention to treat. Multi‐level analysis accounted for site heterogeneity of effect. Findings: Self‐reported 6‐month sustained abstinence was 21.5% for the intervention group versus 9.3% for the control group [relative risk (RR) = 2.29, 95% confidence interval (CI) = 1.34, 3.92]. Biochemically verified 6‐month sustained abstinence was also higher in the intervention group (RR 2.21, 95% CI = 1.08, 4.51) for the 166 participants who were offered carbon monoxide testing. Self‐reported 3‐month sustained abstinence was 25.4% for the intervention group and 12.8% for the control group (RR = 1.98, 95% CI = 1.24, 3.18). Conclusions: Motivational interviewing by lay counsellors to promote smoking cessation in tuberculosis patients in S outh A frica approximately doubled sustained smoking abstinence for at least 6 months compared with brief advice alone.

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  • Single-session brief interventions resulted in reduced tobacco use at 6 months.

    “The BI resulted in reduced tobacco use at month 3 [55,56], and at 6 months [56,62].”
  • Some studies found no effect on total ASSIST scores.

    “Some studies found no effect on total Alcohol Smoking and Substance Involvement Screening Test (ASSIST) scores [62,68], while others reported a statistically significant reduction in total ASSIST scores [49,69].”

    From A scoping review of substance use brief interventions in Africa (2024) · cites this paper as [62]

    The Outcome measures section defines smoking abstinence and quit attempts as outcomes, and the Primary outcome section reports smoking-cessation results. A search for ASSIST, its full name, and total substance-involvement scores found no passage reporting a total ASSIST score or an effect on it. (LLM, conf=0.76)

    Experimental — accuracy not yet measured
  • Single-session brief interventions resulted in reduced alcohol use at 3 months.

    “Concerning alcohol use, single session BI resulted in reduced use at month 1 [50,54]; 6 weeks [72], 3 months [50,61–64], and 6 months [50,52,60,72].”

    From A scoping review of substance use brief interventions in Africa (2024) · cites this paper as [62]

    The Outcome measures and Secondary outcomes sections (page not available in our copy) report smoking abstinence at three months, not alcohol use. A search for alcohol-use outcomes found alcohol mentioned as an adjustment variable, but no result showing reduced alcohol use at three months. (LLM, conf=0.76)

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2 of the 69 references couldn’t be matched to a known paper.

Research works printed but not linked: 5

  1. Rollnick S., Butler C. C., Stott N. Helping smokers make deci- sions: the enhancement of brief intervention for general medical practice. Patient Educ Couns 1997; 31: 191-203.
  2. Heckman C. J., Egleston B. L., Hofmann M. T. Efficacy of motivational interviewing for smoking cessation: a system- atic review and meta-analysis. Tob Control 2010; 19: 410-6.
  3. Department of Health Republic of South Africa. Government Gazette Vol. 554, No.34523. National Health Act (61/2003): Policy on National Health Insurance. Pretoria: Government Printing Works; 2011. References
  4. Miller WR, Rollnick.S. 1991, " Chapter 5. Principles of Motivational Interviewing" in Motivational interviewing. Preparing People to Change Addictive Behaviours. The Guilford Press, New York/London, pp.51-63.
  5. Rollnick S, M.W. 1995, "What is motivational interviewing?", Behavioral and Cognitive Psychotherapy, vol. 23, pp. 325-334.

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Authors
Louwagie, G. M. C., Okuyemi, K. S., & Ayo‐Yusuf, O. A.
Affiliations
  • University of Pretoria (ZA)
  • University of Minnesota (US)
  • School of Health Systems and Public Health Faculty of Health Sciences University of Pretoria South Africa
Corresponding author
Louwagie, Goedele M. C.
Venue
Addiction
Publisher
Wiley
Published
2014-07-18
Volume
109
Issue
11
Pages
1942-1952
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W2111028651
Cited by
72
References
69
Citations by year
2026: 2 · 2025: 5 · 2024: 7 · 2023: 9 · 2022: 6 · 2021: 4 · 2020: 10 · 2019: 7 · 2018: 8 · 2017: 3 · 2016: 5 · 2015: 5 · 2014: 1
FWCI
3.10
Type
journal article
Language
en
Open access
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
  • UpSpace Institutional Repository (University of Pretoria) (submittedVersion)
Funders
  • Global Bridges Health Care Alliance for Tobacco Dependence Treatment
  • KNCV tuberculosis foundation (Grant 12.402.2/MvdW/U.10.0696/cal)
  • National Research Foundation South Africa (Grant# 80843)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Medicine › Infectious Diseases › Tuberculosis Research and Epidemiology
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
motivational interviewing, smoking cessation, tuberculosis, smoking abstinence, exhaled carbon monoxide, primary health centers, Tshwane
MeSH terms
Smoking Prevention, Adult, Female, Follow-Up Studies, Health Facilities, Humans, Male, Middle Aged, Smoking, South Africa, Tuberculosis, Smoking Cessation, Treatment Outcome, Multilevel Analysis, Motivational Interviewing

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