Cited by 57Gambling Behavior and TreatmentsSubstance Abuse Treatment and OutcomesPersonality Disorders and Psychopathology

Towards a comprehensive developmental model of pathological gambling

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Blanco, Carlos, Hanania, Joan, Petry, Nancy M., Wall, Melanie M., Wang, Shuai, Jin, Chelsea J., Kendler, Kenneth S.·2015·Addiction

Abstract

Aims: To develop a comprehensive etiological model of pathological gambling (PG) for men and women based on Kendler's development model for major depression, which groups 22 risk factors into five developmental tiers (childhood, early adolescence, late adolescence, adulthood, last year). We hypothesized that: (1) all risk factors would be associated significantly with PG; (2) the effect of risk factors in earlier developmental tiers would be accounted for by later tiers; and (3) there would be few gender differences. Design: Separate models were built for life‐time gambling and for 12‐month PG among those with life‐time gambling. Setting: Data drawn from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) in the United States. Participants: Respondents to NESARC wave 1 (n = 43 093). Measurements: Odds ratios (OR) and adjusted OR (AOR) were used to determine the risk factors in multiple models. Findings: After mutually adjusting for other risk factors, family history of substance use disorders (SUD) or depression, impulsivity, childhood‐onset anxiety, number of Axis I and II disorders, history of SUD, nicotine dependence, social deviance in adulthood, and past‐year history of SUD, nicotine dependence and independent stressful life events predicted life‐time gambling. Past history of PG, number of personality disorders and past year nicotine dependence were associated significantly with 12‐month PG (all P < 0.05). There were no significant gender interactions for 12‐month PG. Conclusions: A modification of Kendler's model for major depression provides a foundation for the development of a comprehensive developmental model of pathological gambling. Life‐time history of gambling and 12‐month pathological gambling appear to be determined by risk factors in several developmental levels, with the effect of earlier development tiers accounted for by later ones.

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  1. [46]Kendler KS Gardner CO Prescott CA Am J Psychiatry 2006 163 115 24 16390898

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Authors
Blanco, C., Hanania, J., Petry, N. M., Wall, M. M., Wang, S., Jin, C. J., & Kendler, K. S.
Affiliations
  • New York State Psychiatric Institute (US)
  • University of Connecticut (US)
  • Virginia Commonwealth University (US)
Venue
Addiction
Publisher
Wiley
Published
2015-06-06
Volume
110
Issue
8
Pages
1340-1351
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
OpenAlex
W1516572448
Cited by
57
References
83
Citations by year
2026: 3 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 3 · 2021: 6 · 2020: 2 · 2019: 11 · 2018: 7 · 2017: 13 · 2016: 7
FWCI
11.18
Type
journal article
Language
en
Open access
Locations
  • Addiction (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institutes of Health (DA019606, DA023200, DA023973, CA133050, MH082773, DA023918, DA021567, DA027615, DA022739, DA024667, DA09241, AA03510)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Gambling Behavior and Treatments
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
  • Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords
gambling addiction, developmental model, etiology, risk factors, gender differences, nicotine dependence, personality disorders, substance use disorders, impulsivity, childhood anxiety, life events
MeSH terms
Adolescent, Adult, Aged, Anxiety, Depression, Female, Gambling, Humans, Impulsive Behavior, Life Change Events, Male, Middle Aged, Models, Psychological, Personality Disorders, Risk Factors, Social Behavior Disorders, Socioeconomic Factors, United States, Age Distribution, Sex Distribution, Substance-Related Disorders, Young Adult, Self Report

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