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Cited by 10Sperm and Testicular FunctionMale Reproductive Health StudiesReproductive Health and Technologies

Efficacy of varicocelectomy in primary infertile patients with isolated teratozoospermia. A retrospective analysis

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Ilktac, Abdullah, Hamidli, Seyidali, Ersoz, Cevper, Dogan, Bayram, Akcay, Muzaffer·2020·Andrologia
DOI 10.1111/and.13875
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Abstract

The present study assessed the results of varicocelectomy in patients with isolated teratozoospermia. Sixty-two infertile men with isolated teratozoospermia were evaluated retrospectively. There were significant improvements between preoperative and postoperative mean percentages of spermatozoa with normal morphology (1.15 ± 1.1% versus 2.3 ± 1.8%, p < .001) and spermatozoa with head abnormalities (92.9 ± 4.5% versus 88.6 ± 7.4%, p < .001). Nineteen (31%) patients had children through natural conception, 4 (6%) patients had children with assisted reproductive techniques and 39 (63%) patients had got no children within a mean follow-up period of 31.3 months. In patients who had children with natural conception, significant improvements were detected in postoperative mean percentages of spermatozoa with normal morphology (p < .001), head abnormalities (p < .001), neck/midpiece abnormalities (p = .003) and tail abnormalities (p = .007). When semen parameters of men who had children via natural conception was compared with the men with no children, we found that the percentage of spermatozoa with normal morphology was significantly higher (p = .008) and percentage of spermaztozoa with head anomalies was significantly lower (p = .019) in men who had children via natural conception. We believe that varicocelectomy is a beneficial surgical method for the treatment of isolated teratozoospermia and better postoperative rates of spermatozoa having normal morphology and head abnormalities are related with natural conception.

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  • Several studies have evaluated the role of varicocelectomy and antioxidants in improving sperm morphology, particularly for immature sperm and those with head and tail defects based on Kruger's classification.

    “Several studies have evaluated the role of varicocelectomy and antioxidants in improving sperm morphology, particularly for immature sperm and those with head and tail defects based on Kruger’s classification (97-104).”

    From Isolated teratozoospermia: revisiting its relevance in male infertility: a narrative review (2024) · cites this paper as [99]

    The Methods section says sperm morphology was assessed using Kruger’s strict criteria, and the Results report improved normal morphology and fewer head abnormalities after varicocelectomy. Tail abnormalities improved only in the subgroup whose partners conceived naturally, not in the full group. The paper does not evaluate antioxidant treatment or report an improvement specifically in immature sperm; its discussion of increased antioxidant capacity concerns an effect of varicocelectomy. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

  • Among men who underwent varicocelectomy, those who attained natural conception had a higher rate of sperm with normal morphology and a lower rate of sperm with head anomalies compared to those who failed to achieve pregnancy or those who should undergo ART.

    “Furthermore, Ilktac et al. observed that subjects who attained natural conception after varicocelectomy had a higher rate of sperm with normal morphology and a lower rate of sperm with head anomalies compared to those who failed to achieve pregnancy or those who should undergo ART (99).”

    From Isolated teratozoospermia: revisiting its relevance in male infertility: a narrative review (2024) · cites this paper as [99]

    The Abstract and Table 4 report higher postoperative normal sperm morphology and fewer head abnormalities among men who conceived naturally than among men who had no children. The paper mentions four men who had children through assisted reproductive techniques, but the cited comparison is with the no-children group; it does not establish the same comparison with men who underwent or should undergo ART. (LLM, conf=0.88)

    Experimental — accuracy not yet measured

  • Around one-sixth to one-third of subjects with isolated teratozoospermia achieve spontaneous pregnancy after varicocelectomy.

    “Studies also found that around one-sixth to one-third of subjects with isolated teratozoospermia achieve spontaneous pregnancy after varicocelectomy (98,99).”

    From Isolated teratozoospermia: revisiting its relevance in male infertility: a narrative review (2024) · cites this paper as [99]

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Cited by

Sorted by citations

Authors
Ilktac, A., Hamidli, S., Ersoz, C., Dogan, B., & Akcay, M.
Affiliations
  • Department of Urology Faculty of Medicine Bezmialem Vakif University Istanbul Turkey
  • Bezmiâlem Vakıf Üniversitesi (TR)
ORCID
Venue
Andrologia
Publisher
Wiley
Published
2020-10-28
Volume
52
Issue
11
Pages
e13875-e13875
ISSN
  • 0303-4569 (ISSN-L)
  • 1439-0272
DOI
10.1111/and.13875
OpenAlex
W3096872736
Cited by
10
References
3
Citations by year
2025: 2 · 2024: 5 · 2023: 1 · 2022: 1 · 2021: 1
FWCI
0.66
Type
journal article
Language
en
Open access
Licence
Locations
  • Andrologia (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Sperm and Testicular Function
  • Health Sciences › Health Professions › General Health Professions › Male Reproductive Health Studies
  • Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
Keywords
varicocelectomy, teratozoospermia, male infertility, sperm morphology, sperm head abnormalities, spontaneous conception, assisted reproduction
MeSH terms
Teratozoospermia, Child, Humans, Infertility, Male, Male, Retrospective Studies, Spermatozoa, Varicocele

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