Effect of Dietary Fish Oil Intake on Ubiquitin Ligase Expression During Muscle Atrophy Induced by Sciatic Nerve Denervation in Mice
Abstract
Dietary fish oil intake improves muscle atrophy in several atrophy models however the effect on denervation-induced muscle atrophy is not clear. Thus, the aim of this study was to investigate the effects of dietary fish oil intake on muscle atrophy and the expression of muscle atrophy markers induced by sciatic nerve denervation in mice. We performed histological and quantitative mRNA expression analysis of muscle atrophy markers in mice fed with fish oil with sciatic nerve denervation. Histological analysis indicated that dietary fish oil intake slightly prevented the decrease of muscle fiber diameter induced by denervation treatment. In addition, dietary fish oil intake suppressed the MuRF1 (tripartite motif-containing 63) expression up-regulated by denervation treatment, and this was due to decreased tumor necrosis factor-alpha (TNF-α) production in skeletal muscle. We concluded that dietary fish oil intake suppressed MuRF1 expression by decreasing TNF-α production during muscle atrophy induced by sciatic nerve denervation in mice.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Dietary menhaden fish oil intake suppresses MuRF1 expression by decreasing TNF-α production in denervation-induced muscle atrophy in C57BL/6J mice.
“Recently, in another study, dietary menhaden fish oil intake suppresses MuRF1 expression by decreasing TNF-α production in denervation-induced muscle atrophy in C57BL/6J mice [77].”
From Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy (2021) · cites this paper as [77]
Cites
Identification of ubiquitin ligases required for skeletal muscle atrophy.
Bodine, S. C., Latres, E., Baumhueter, S., Lai, V. K.-M., Nunez, L., Clarke, B. A., Poueymirou, W. T., Panaro, F. J., Na, E., Dharmarajan, K., et al. (2001) · Science · doi:10.1126/science.1065874 · Cited by 3,521 · see citing works
n−3 Polyunsaturated fatty acids, inflammation, and inflammatory diseases
Calder, P. C. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.6.1505s · Cited by 2,525 · see citing works
IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice
Cai, D., Frantz, J. D., Tawa, N. E., Melendez, P. A., Oh, B.-C., Lidov, H. G. W., Hasselgren, P.-O., Frontera, W. R., Lee, J., Glass, D. J., et al. (2004) · Cell · doi:10.1016/j.cell.2004.09.027 · Cited by 1,367 · see citing works
Skeletal muscle hypertrophy and atrophy signaling pathways
Glass, D. J. (2005) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2005.04.018 · Cited by 1,106 · see citing works
The Molecular Basis of Skeletal Muscle Atrophy
Jackman, R. W., & Kandarian, S. C. (2004) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00579.2003 · Cited by 1,008 · see citing works
Smith, G. I., Atherton, P., Reeds, D. N., Mohammed, B. S., Rankin, D., Rennie, M. J., & Mittendorfer, B. (2011) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.005611 · Cited by 665 · see citing works
Sacheck, J. M., Hyatt, J. K., Raffaello, A., Thomas Jagoe, R., Roy, R. R., Reggie Edgerton, V., Lecker, S. H., & Goldberg, A. L. (2007) · The FASEB Journal · doi:10.1096/fj.06-6604com · Cited by 585 · see citing works
Kamei, Y., Miura, S., SUZUKI, M. T., Kai, Y., Mizukami, J., Taniguchi, T., Mochida, K., Tomoko, H. A. T. A., Matsuda, J., Aburatani, H., et al. (2004) · Journal of Biological Chemistry · doi:10.1074/jbc.m400674200 · Cited by 574 · see citing works
FoxO transcription factors: their roles in the maintenance of skeletal muscle homeostasis
Sanchez, A. M. J., Candau, R. B., & Bernardi, H. (2013) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-013-1513-z · Cited by 335 · see citing works
Whitehouse, A., Smith, H. J., Drake, J. L., & Tisdale, M. J. (2001) · PubMed · Cited by 226 · see citing works
Effect of nutritional deprivation on diaphragm contractility and muscle fiber size
Lewis, M. I., Sieck, G. C., Fournier, M., et al. (1986) · Journal of Applied Physiology · doi:10.1152/jappl.1986.60.2.596 · Cited by 136 · see citing works
Kamolrat, T., & Gray, S. R. (2013) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2013.02.041 · Cited by 108 · see citing works
Magee, P., Pearson, S., & Allen, J. (2008) · Lipids in Health and Disease · doi:10.1186/1476-511x-7-24 · Cited by 105 · see citing works
Downregulation of ubiquitin-dependent proteolysis by eicosapentaenoic acid in acute starvation
Whitehouse, A. S., & Tisdale, M. J. (2001) · Biochemical and Biophysical Research Communications · doi:10.1006/bbrc.2001.5209 · Cited by 100 · see citing works
You, J.-S., Park, M.-N., Song, W., & Lee, Y.-S. (2010) · Applied Physiology Nutrition and Metabolism · doi:10.1139/h10-022 · Cited by 88 · see citing works
Polyunsaturated Fatty Acids and Their Relation with Bone and Muscle Health in Adults
Mangano, K. M., Sahni, S., Kerstetter, J. E., Kenny, R. A., & Hannan, M. T. (2013) · Current Osteoporosis Reports · doi:10.1007/s11914-013-0149-0 · Cited by 79 · see citing works
Liu, Y., Chen, F., Odle, J., Lin, X., Zhu, H., Shi, H., Hou, Y., & Yin, J. (2013) · The Journal of Nutrition · doi:10.3945/jn.113.176255 · Cited by 74 · see citing works
Uchida, T., Sakashita, Y., Kitahata, K., Yamashita, Y., Tomida, C., Kimori, Y., Komatsu, A., Hirasaka, K., Ohno, A., Nakao, R., et al. (2018) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00184.2017 · Cited by 62 · see citing works
Komiya, Y., Sawano, S., Mashima, D., Ichitsubo, R., Nakamura, M., Tatsumi, R., Ikeuchi, Y., & Mizunoya, W. (2017) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-017-9468-6 · Cited by 61 · see citing works
Self-citationHirasaka, K., Maeda, T., Ikeda, C., HARUNA, M., Kohno, S., Abe, T., Ochi, A., Mukai, R., Oarada, M., Kondo, S., et al. (2013) · Journal of Nutritional Science and Vitaminology · doi:10.3177/jnsv.59.317 · Cited by 59 · see citing works
Novel Intriguing Strategies Attenuating to Sarcopenia
Sakuma, K., & Yamaguchi, A. (2012) · Journal of Aging Research · doi:10.1155/2012/251217 · Cited by 58 · see citing works
Castillero, E., Martín, A. I., López-Menduiña, M., Villanúa, M. A., & López-Calderón, A. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00388.2009 · Cited by 53 · see citing works
Downregulation of muscle protein degradation in sepsis by eicosapentaenoic acid (EPA)
Khal, J., & Tisdale, M. J. (2008) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2008.08.004 · Cited by 51 · see citing works
Kamolrat, T., Gray, S. R., & Thivierge, M. C. (2012) · European Journal of Nutrition · doi:10.1007/s00394-012-0368-7 · Cited by 46 · see citing works
Slow myosin heavy chain expression in the absence of muscle activity
Agbulut, O., Vignaud, A., Hourdé, C., Mouisel, É., Fougerousse, F., Butler-Browne, G. S., & Ferry, A. (2008) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00408.2008 · Cited by 42 · see citing works
Sato, Y., Shimizu, M., Mizunoya, W., et al. (2009) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.90085 · Cited by 34 · see citing works
Shin, S. K., Kim, J. H., Lee, J. H., Son, Y. H., Lee, M. W., Kim, H. J., Noh, S. A., Kim, K. P., Kim, I. G., & Lee, M. J. (2017) · Experimental & Molecular Medicine · doi:10.1038/emm.2016.133 · Cited by 33 · see citing works
Abe, T., Kohno, S., Yama, T., Ochi, A., Suto, T., Hirasaka, K., Ohno, A., Teshima-Kondo, S., Okumura, Y., Oarada, M., et al. (2013) · International Journal of Endocrinology · doi:10.1155/2013/907565 · Cited by 32 · see citing works
Zhang, J., Xu, X., Liu, Y., Zhang, L., Odle, J., Lin, X., Zhu, H., Wang, X., & Liu, Y. (2019) · Genes · doi:10.3390/genes10010064 · Cited by 31 · see citing works
Impact of denervation‐induced muscle atrophy on housekeeping gene expression in mice
Nakao, R., Yamamoto, S., Yasumoto, Y., Kadota, K., & Oishi, K. (2014) · Muscle & Nerve · doi:10.1002/mus.24310 · Cited by 30 · see citing works
Distinct signal transductions in fast- and slow- twitch muscles upon denervation
Gao, H., & Li, Y. (2018) · Physiological Reports · doi:10.14814/phy2.13606 · Cited by 19 · see citing works
Fappi, A., Neves, J. D. C., Kawasaki, K. A., Bacelar, L., Sanches, L. N., da Silva, F. P., Larina-Neto, R., Chadi, G., & Zanoteli, E. (2019) · Physiological Reports · doi:10.14814/phy2.13966 · Cited by 13 · see citing works
Castillero, E., López-Menduiña, M., Martı́n, A. I., Villanúa, M. Á., & López‐Calderón, A. (2011) · Journal of Endocrinology · doi:10.1530/joe-11-0170 · Cited by 11 · see citing works
n-3 Fatty acids preserve muscle mass and insulin sensitivity in a rat model of energy restriction
Galmiche, G., Huneau, J., Mathé, V., Mourot, J., Simon, N., Guillou, C. L., & Hermier, D. (2016) · British Journal Of Nutrition · doi:10.1017/s0007114516003111 · Cited by 7 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy
Wang, Y., Liu, Q., Quan, H., Kang, S.-G., Huang, K., & Tong, T. (2021) · Nutrients · doi:10.3390/nu13061914 · Cited by 61 · see citing works
- Authors
- Komiya, Y., Kobayashi, C., Uchida, N., Otsu, S., Tanio, T., Yokoyama, I., Nagasao, J., & Arihara, K.
- Affiliations
- Kitasato University (JP)
- Corresponding author
- Komiya, Yusuke
- Venue
- Animal Science Journal
- Publisher
- Wiley
- Published
- 2019-05-27
- Volume
- 90
- Issue
- 8
- Pages
- 1018-1025
- ISSN
- 1344-3941 (ISSN-L)
- 1740-0929
- OpenAlex
- W2947997928
- Cited by
- 12
- References
- 34
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 3 · 2020: 1
- FWCI
- 0.50
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Animal Science Journal (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Japan Society for the Promotion of Science (17K15272)
- Kitasato University
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Muscle Physiology and Disorders
- Health Sciences › Nursing › Nutrition and Dietetics › Fatty Acid Research and Health
- Health Sciences › Medicine › Physiology › Nutrition and Health in Aging
- Keywords
- dietary fish oil, muscle atrophy, sciatic nerve denervation, ubiquitin ligase, MuRF1, TNF-α, skeletal muscle, muscle fiber diameter, omega-3 fatty acids, denervation-induced atrophy
- MeSH terms
- Tripartite Motif Proteins, Animals, Denervation, Dietary Fats, Unsaturated, Fish Oils, Male, Mice, Inbred C57BL, Muscle Proteins, Muscular Atrophy, RNA, Messenger, Sciatic Nerve, Tumor Necrosis Factor-alpha, Up-Regulation, Gene Expression, Muscle, Skeletal, Muscle Fibers, Skeletal, Ubiquitin-Protein Ligases
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review