Predictive validity of objective measures of physical fitness for the new onset of mental disorders in adolescents and young adults
Open accessAbstract
Aim: To systematically review evidence that objectively assessed level of physical fitness is associated with future risk of adverse mental health outcomes during the peak age range for onset of adult mental disorders. Methods: Searches of Electronic databases (EBSCOhost, SPORTDISCUS, EMBASE, MedLINE, Cochrane database, CINAHL, PsychInfo, and Dissertation Abstracts), supplemented by hand searches of journals, conference proceedings and citations. Random‐effects meta‐analysis models were used to pool the intervention effects. Results: Eight studies of adolescents and young adults were included in the qualitative review and six studies derived from four independent cohorts were included in the statistical analyses. Most publications reported on large samples (including >1 million), but male conscripts were over‐represented in the study cohorts; quality of included studies was modest, and heterogeneity was significant. Meta‐analytic estimates were conducted for different adverse mental health outcomes, but all showed an inverse association between fitness and incidence of mental disorders or suicidality. Overall, higher level of physical fitness was associated with lower rates of onset of mental health problems (odds ratio: 0.59; 95% confidence intervals: 0.54, 0.65). Conclusions: All eligible studies were undertaken since 2010, suggesting this is an emerging but unfinished field of research. The study design and methodological limitations indicate that the reported results should be treated with caution. However, if the meta‐analytic findings are reliably replicated for new cohorts of males and females, they have implications for research into the prevention of non‐communicable diseases, as our review suggests that interventions should target physical and mental health in equal measure.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Cardiorespiratory fitness reduces risk of psychiatric disorders.
“with growing evidence of cardiorespiratory fitness itself reducing risk of psychiatric disorders 85-87”
From A meta-review of "lifestyle psychiatry": the role of exercise, smoking, diet and sleep in the prevention and treatment of mental disorders (2020) · cites this paper as [87]
Cites
Measuring inconsistency in meta-analyses
Higgins, J. P. T., Thompson, S. G., Deeks, J. J., & Altman, D. G. (2003) · BMJ · doi:10.1136/bmj.327.7414.557 · Cited by 63,139 · see citing works
Bias in meta-analysis detected by a simple, graphical test
Egger, M., Smith, G. D., Schneider, M., & Minder, C. (1997) · BMJ · doi:10.1136/bmj.315.7109.629 · Cited by 56,722 · see citing works
PRISMA-P Group, Moher, D., Shamseer, L., Clarke, M., Ghersi, D., Liberati, A., Petticrew, M., Shekelle, P., & Stewart, L. A. (2015) · Systematic Reviews · doi:10.1186/2046-4053-4-1 · Cited by 26,223 · see citing works
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gotzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · BMJ · doi:10.1136/bmj.b2700 · Cited by 17,648 · see citing works
Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Annals of Internal Medicine · doi:10.7326/0003-4819-151-4-200908180-00136 · Cited by 10,349 · see citing works
Physical fitness in childhood and adolescence: a powerful marker of health
Ortega, F. B., Ruiz, J. R., Castillo, M. J., & Sjöstróm, M. (2007) · International Journal of Obesity · doi:10.1038/sj.ijo.0803774 · Cited by 2,885 · see citing works
Physical activity and mental health in children and adolescents: a review of reviews
Biddle, S. J. H., & Asare, M. (2011) · British Journal of Sports Medicine · doi:10.1136/bjsports-2011-090185 · Cited by 2,447 · see citing works
Warren, J. M., Ekelund, U., Besson, H., Mezzani, A., Geladas, N., & Vanhees, L. (2010) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e32832ed875 · Cited by 587 · see citing works
Firth, J., Stubbs, B., Rosenbaum, S., Vancampfort, D., Malchow, B., Schuch, F., Elliott, R., Nuechterlein, K. H., & Yung, A. R. (2016) · Schizophrenia Bulletin · doi:10.1093/schbul/sbw115 · Cited by 488 · see citing works
The Current State of Physical Activity Assessment Tools
Ainsworth, B. E., Cahalin, L. P., Buman, M. P., & Ross, R. (2014) · Progress in Cardiovascular Diseases · doi:10.1016/j.pcad.2014.10.005 · Cited by 441 · see citing works
Physical activity and prevalence and incidence of mental disorders in adolescents and young adults
STRÖHLE, A., HÖFLER, M., PFISTER, H., MÜLLER, A.-G., HOYER, J., WITTCHEN, H.-U., & LIEB, R. (2007) · Psychological Medicine · doi:10.1017/s003329170700089x · Cited by 273 · see citing works
Health Survey for England 2008: Physical activity and fitness
Craig, R. T., Mindell, J. S., & Hirani (2009) · Cited by 240 · see citing works
Cardiorespiratory fitness in severe mental illness: a systematic review and meta-analysis
Vancampfort, D., Rosenbaum, S., Schuch, F., Ward, P. B., Richards, J., Mugisha, J., Probst, M., & Stubbs, B. (2017) · Sports Medicine · doi:10.1007/s40279-016-0574-1 · Cited by 224 · see citing works
Physical activity and depressive symptoms in adolescents: a prospective study
Rothon, C., Edwards, P., Bhui, K., Viner, R. M., Taylor, S., & Stansfeld, S. A. (2010) · BMC Medicine · doi:10.1186/1741-7015-8-32 · Cited by 204 · see citing works
Stubbs, B., Rosenbaum, S., Vancampfort, D., Ward, P. B., & Schuch, F. B. (2016) · Journal of Affective Disorders · doi:10.1016/j.jad.2015.10.010 · Cited by 163 · see citing works
Sassen, B., Cornelissen, V., Kiers, H., Wittink, H., Kok, G., & Vanhees, L. (2009) · European Journal of Cardiovascular Prevention & Rehabilitation · doi:10.1097/hjr.0b013e3283312e94 · Cited by 151 · see citing works
Prospective study of cardiorespiratory fitness and depressive symptoms in women and men
Sui, X., Laditka, J. N., Church, T. S., Hardin, J. W., Chase, N. L., Davis, K. E., & Blair, S. N. (2008) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2008.08.002 · Cited by 147 · see citing works
Physical fitness in adolescents with normal weight and overweight
Fogelholm, M., Stigman, S., Huisman, T., & Metsämuuronen, J. (2007) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2007.00685.x · Cited by 124 · see citing works
Åberg, M., Wærn, M., Nyberg, J., Pedersen, N. L., Bergh, Y., Åberg, N. D., Nilsson, M., Kuhn, H. G., & Torén, K. (2012) · The British Journal of Psychiatry · doi:10.1192/bjp.bp.111.103416 · Cited by 112 · see citing works
Schuch, F. B., Vancampfort, D., Sui, X., Rosenbaum, S., Firth, J., Richards, J., Ward, P. B., & Stubbs, B. (2016) · Preventive Medicine · doi:10.1016/j.ypmed.2016.10.011 · Cited by 111 · see citing works
Physical activity and health-related fitness in youth: amultivariate analysis
Katzmarzyk, P. T., Malina, R. M., Song, T. M. K., & Bouchard, C. (1998) · Medicine & Science in Sports & Exercise · doi:10.1097/00005768-199805000-00011 · Cited by 110 · see citing works
Exercise, fitness, and health: the consensus statement.
Bouchard, C., Shephard, R. J., Stephens, T. W., et al. (1990) · Cited by 95 · see citing works
Koivukangas, J., Tammelin, T., Kaakinen, M., Mäki, P., Moilanen, I., Taanila, A., & Veijola, J. (2010) · Schizophrenia Research · doi:10.1016/j.schres.2009.10.022 · Cited by 88 · see citing works
Latvala, A., Kuja-Halkola, R., Rück, C., D’Onofrio, B. M., Jernberg, T., Almqvist, C., Mataix-Cols, D., Larsson, H., & Lichtenstein, P. (2016) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2016.2717 · Cited by 82 · see citing works
Baumeister, S. E., Leitzmann, M. F., Bahls, M., Dörr, M., Schmid, D., Schomerus, G., Appel, K., Markus, M. R. P., Völzke, H., Gläser, S., et al. (2017) · The Journal of Clinical Psychiatry · doi:10.4088/jcp.15m10474 · Cited by 72 · cited 2× · see citing works
“Four studies reported several mental outcomes including mood, anxiety, psychotic, and other disorders (Baumeister et al., 2017; Gubata et al., 2013; Nyberg et al., 2018; Taanila et al., 2011); two studies report mood disorder outcomes (Aberg et al., 2012; Ruggero et al., 2015); one study focused on…”
BackgroundDecline in Cardiorespiratory Fitness and Odds of Incident Depression
Dishman, R. K., Sui, X., Church, T. S., Hand, G. A., Trivedi, M. H., & Blair, S. N. (2012) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2012.06.011 · Cited by 67 · see citing works
Taanila, H., Hemminki, A. J., Suni, J. H., PIHLAJAMÄKI, H. K., & Parkkari, J. P. (2011) · BMC Public Health · doi:10.1186/1471-2458-11-590 · Cited by 58 · see citing works
Cardiorespiratory Fitness May Help in Protecting Against Depression Among Middle School Adolescents
Ruggero, C. J., Petrie, T. A., Sheinbein, S. T., Greenleaf, C. A., & Martin, S. B. (2015) · Journal of Adolescent Health · doi:10.1016/j.jadohealth.2015.03.016 · Cited by 52 · see citing works
SU106. Investigating the Short- and Long-Term Benefits of Exercise in Early Psychosis
Firth, J., Carney, R., French, P., Elliott, R., & Yung, A. R. (2017) · Schizophrenia Bulletin · doi:10.1093/schbul/sbx024.102 · Cited by 46 · see citing works
Secular trends in aerobic fitness performance in a cohort of Norwegian adolescents
Dyrstad, S. M., van den Berg, T. I. J., & Tjelta, L. I. (2011) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2011.01315.x · Cited by 39 · see citing works
Åberg, M., Nyberg, J., Torén, K., Wallin, A. S., Kuhn, H. G., & Wærn, M. (2013) · Psychological Medicine · doi:10.1017/s0033291713001207 · Cited by 38 · see citing works
Veses, A. M., Martínez‐Gómez, D., Gómez‐Martínez, S., Vicente‐Rodríguez, G., Castillo, R., Ortega, F. B., González‐Gross, M., Calle, M. E., Veiga, Ó. L., Marcos, A., et al. (2013) · Pediatric Obesity · doi:10.1111/j.2047-6310.2012.00138.x · Cited by 32 · see citing works
Suetani, S., Mamun, A. A., Williams, G. M., Najman, J. M., McGrath, J. J., & Scott, J. G. (2017) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2017.06.013 · Cited by 32 · see citing works
Self-citationGubata, M. E., Urban, N., Cowan, D. N., & Niebuhr, D. W. (2013) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2013.04.003 · Cited by 31 · see citing works
Kaseva, K., Rosenström, T. H., Hintsa, T., Pulkki-Råbäck, L., Tammelin, T., Lipsanen, J. O., Yang, X., Hintsanen, M., Hakulinen, C. A., Pahkala, K., et al. (2016) · Journal of Sports Medicine · doi:10.1155/2016/8947375 · Cited by 20 · see citing works
Nyberg, J., Henriksson, M., Åberg, M., Rosengren, A., Söderberg, M., Åberg, N. D., Kuhn, H. G., & Wærn, M. (2017) · Psychological Medicine · doi:10.1017/s0033291717001763 · Cited by 17 · see citing works
Kuiper, J., Broer, J., & van der Wouden, J. C. (2017) · European Journal of Public Health · doi:10.1093/eurpub/ckx230 · Cited by 9 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Firth, J., Solmi, M., Wootton, R. E., Vancampfort, D., Schuch, F. B., Hoare, E., Gilbody, S., Torous, J., Teasdale, S. B., Jackson, S. E., et al. (2020) · World Psychiatry · doi:10.1002/wps.20773 · Cited by 1,148 · see citing works
Giusti, L., Bianchini, V., Aggio, A., Mammarella, S., Salza, A., Necozione, S., Alunno, A., Ferri, C., Casacchia, M., & Roncone, R. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.903759 · Cited by 6 · see citing works
- Authors
- Tacchi, M. J., Heggelund, J., & Scott, J.
- Affiliations
- Cumbria Northumberland Tyne and Wear NHS Foundation Trust (GB)
- Department of Mental Health Norwegian University of Science and Technology Trondheim Norway
- Newcastle University (GB)
- Corresponding author
- Scott, Jan
- ORCID
- Scott, Jan
- Venue
- Early Intervention in Psychiatry
- Publisher
- Wiley
- Published
- 2019-01-21
- Volume
- 13
- Issue
- 6
- Pages
- 1310-1318
- ISSN
- 1751-7885 (ISSN-L)
- 1751-7893
- OpenAlex
- W2914763920
- Cited by
- 24
- References
- 37
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 5 · 2022: 2 · 2021: 3 · 2020: 6 · 2019: 1
- FWCI
- 0.35
- Type
- journal article
- Language
- en
- Open access
- green
- doi.org
- Locations
- Early Intervention in Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Newcastle University ePrints (Newcastle Univesity)
- References
- Funders
- Research for Patient Benefit Programme
- Medical Research Council Canada
- Topics
- Health Sciences › Medicine › Physiology › Physical Activity and Health
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
- Keywords
- physical fitness, mental illness, adolescents, young adults, predictive validity, suicide, mental health risk, physical activity, non-communicable disease prevention, conscripts
- MeSH terms
- Mental Disorders, Humans, Physical Fitness, Predictive Value of Tests
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review