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Cited by 303

The DOI matches its Crossref record; 55 of the 55 references it cites were found in a registry or an index.

Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II

Yuan, Hsiangkuo, Silberstein, Stephen D.·2016·Headache: The Journal of Head and Face Pain

Abstract

The development of vagus nerve stimulation (VNS) began in the 19th century. Although it did not work well initially, it introduced the idea that led to many VNS‐related animal studies for seizure control. In the 1990s, with the success of several early clinical trials, VNS was approved for the treatment of refractory epilepsy, and later for the refractory depression. To date, several novel electrical stimulating devices are being developed. New invasive devices are designed to automate the seizure control and for use in heart failure. Non‐invasive transcutaneous devices, which stimulate auricular VN or carotid VN, are also undergoing clinical trials for treatment of epilepsy, pain, headache, and others. Noninvasive VNS (nVNS) exhibits greater safety profiles and seems similarly effective to their invasive counterpart. In this review, we discuss the history and development of VNS, as well as recent progress in invasive and nVNS.

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Metadata

Authors
Yuan, H., & Silberstein, S. D.
Venue
Headache: The Journal of Head and Face Pain
Publisher
Wiley
Published
2015-09-18
Volume
56
Issue
2
Pages
259-266
ISSN
  • 0017-8748 (ISSN-L)
  • 1526-4610
OpenAlex
W4243537131
Cited by
303
References
55
FWCI
4.51
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II. https://app.cochat.ai/papers/10.1111/head.12650
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Yuan, H., & Silberstein, S. D. (2016). Vagus Nerve and Vagus Nerve Stimulation, a Comprehensive Review: Part II. Headache: The Journal of Head and Face Pain. https://doi.org/10.1111/head.12650

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.