The DOI matches its Crossref record, with a small difference in title or year; 71 of the 71 references it cites were found in a registry or an index.
NF‐κB: roles and regulation in different CD 4+ T‐cell subsets
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Summary: The nuclear factor‐κB (NF‐κB) family of transcription factors plays important roles in various biological processes including apoptosis, stress response, immunity, and inflammation. NF‐κB signaling is involved in both immune cell development and function, and it is critical in modulation of the immune response through the transcriptional regulation of cytokine and chemokine expression. An area of great interest in T‐cell‐mediated adaptive immunity is the ability of naive CD 4+ T cells generated in the thymus to differentiate into various subsets including T‐helper 1 (Th1), Th2, Th17, Th9, follicular helper T (Tfh), Th22, and regulatory T (Treg) cells, upon encountering different pathogens and microenvironments. In this review, we discuss the role of NF‐κB pathway in the development and functional divergence of the different helper T‐cell subsets as well as in regulatory T cells.
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From Inferring gene regulatory networks from single-cell multiome data using atlas-scale external data (2025) · cites this paper as [78]
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ABCD of IA: A multi-scale agent-based model of T cell activation in inflammatory arthritis
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“MPRA experiment is performed to screen noncoding SNVs in 25 significant GWAS loci associated with AD and nine loci associated with PSP in the HEK293T cell line [41] loci associated with melanoma [43].”
MethodLevonorgestrel enhanced Toxoplasma gondii infection risk via progesterone receptor upregulation
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Future prospective of microbiome-gut brain axis for treatment of CNS disorders
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Role of NF-KB signaling in recurrent pregnancy loss
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БИОЛОГИЧЕСКАЯ ЗНАЧИМОСТЬ МЕХАНИЗМА NF-κB ПРИ СТАРЕНИИ
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CD94/NKG2A-Qa-1b axis as a key modulator of vaccine responsiveness in aging populations
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Metadata
- Authors
- Oh, H., & Ghosh, S.
- Affiliations
- Department of Microbiology and Immunology Columbia University New York NY
- Columbia University (US)
- Corresponding author
- Ghosh, Sankar
- ORCID
- Ghosh, Sankar
- Venue
- Immunological Reviews
- Publisher
- Wiley
- Published
- 2013-02-13
- Volume
- 252
- Issue
- 1
- Pages
- 41-51
- ISSN
- 0105-2896 (ISSN-L)
- 1600-065X
- PMC
- PMC3576882
- OpenAlex
- W2070085523
- Cited by
- 408
- References
- 71
- Citations by year
- 2026: 16 · 2025: 36 · 2024: 43 · 2023: 46 · 2022: 43 · 2021: 39 · 2020: 28 · 2019: 25 · 2018: 27 · 2017: 26 · 2016: 26 · 2015: 24 · 2014: 21 · 2013: 7
- FWCI
- 2.15
- Type
- journal article
- Language
- en
- Open access
- green
- europepmc.org
- Locations
- Immunological Reviews (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- U.S. Public Health Service (R37-33443, R01-68977)
- National Institute of Allergy and Infectious Diseases (R01AI068977, R37AI033443)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cancer Research › NF-κB Signaling Pathways
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Life Sciences › Immunology and Microbiology › Immunology › Psoriasis: Treatment and Pathogenesis
- Keywords
- NF-κB signaling, CD4+ T cells, T helper cell differentiation, Th1 cells, Th2 cells, Th17 cells, Th9 cells, Th22 cells, T follicular helper cells, regulatory T cells, transcriptional regulation, cytokine and chemokine expression, adaptive immunity, inflammation
- MeSH terms
- Animals, Cell Differentiation, Gene Expression Regulation, Humans, Lymphocyte Activation, Transcription Factors, Transcription, Genetic, Signal Transduction, CD4-Positive T-Lymphocytes, T-Lymphocyte Subsets, Cytokines, NF-kappa B, Mice, Adaptive Immunity
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