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Cited by 271

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

The risk of alcohol

ANDERSON, PETER, CREMONA, ANNE, PATON, ALEX, TURNER, CHARLOTTE, WALLACE, PAUL·1993·Addiction
DOI 10.1111/j.1360-0443.1993.tb03135.x
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Abstract

We have reviewed 156 papers which provided sufficient information to relate individual alcohol consumption to risk for a variety of physical damage. Overall, there was evidence for a dose‐response relationship between level of alcohol consumption and risk of harm for liver cirrhosis, cancers of the oropharynx, larynx, oesophagus, rectum (beer only), liver and breast, and blood pressure and stroke. An increased risk of cardiac arrhythmias, cardiomyopathy and sudden coronary death was associated with heavy drinking. There was evidence for a protective effect of alcohol consumption against risk of coronary heart disease, which could be achieved at consumption levels of less than 10 g alcohol a day. The mortality of non‐drinkers was higher than that of moderate drinkers in some studies. Level of alcohol consumption and total mortality were dose‐related when non‐drinkers were excluded. The finding of a dose‐relationship between alcohol and harm suggested causality. It was not possible to define individual risk for all harms at a given level of alcohol consumption because of variations in methodology, but some idea of the order of magnitude of the increased risk can be obtained from calculating trends of pooled log‐odds ratios. At levels of alcohol consumption of more than 20–30 g a day, all individuals are likely to accumulate risk of harm. Current guidelines on upper limits of lower risk drinking in different countries (168–280 g of alcohol a week for men and 84–140 g a week for women) reflect levels at which the risk of total mortality is not greatly increased above one.

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Crossref · 10.1111/j.1360-0443.1993.tb03135.x

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Metadata

Authors
ANDERSON, P., CREMONA, A., PATON, A., TURNER, C., & WALLACE, P.
Venue
Addiction
Publisher
Wiley
Published
1993-11
Volume
88
Issue
11
Pages
1493-1508
ISSN
  • 0965-2140 (ISSN-L)
  • 1360-0443
DOI
10.1111/j.1360-0443.1993.tb03135.x
OpenAlex
W2046165975
Cited by
271
References
3
FWCI
7.01
Type
journal article
Language
en
Open access
closed

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