Cited by 69Forensic Toxicology and Drug AnalysisAlcohol Consumption and Health EffectsSubstance Abuse Treatment and Outcomes

Unrecorded alcohol consumption in Russia: toxic denaturants and disinfectants pose additional risks

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Solodun, Yuriy, Monakhova, Yulia, Kuballa, Thomas, Samokhvalov, Andriy, Rehm, Jürgen, Lachenmeier, Dirk·2011·Interdisciplinary Toxicology

Abstract

Unrecorded alcohol consumption in Russia: toxic denaturants and disinfectants pose additional risks: In 2005, 30% of all alcohol consumption in Russia was unrecorded. This paper describes the chemical composition of unrecorded and low cost alcohol, including a toxicological evaluation. Alcohol products (n=22) from both recorded and unrecorded sources were obtained from three Russian cities (Saratov, Lipetsk and Irkutsk) and were chemically analyzed. Unrecorded alcohols included homemade samogons, medicinal alcohols and surrogate alcohols. Analysis included alcoholic strength, levels of volatile compounds (methanol, acetaldehyde, higher alcohols), ethyl carbamate, diethyl phthalate (DEP) and polyhexamethyleneguanidine hydrochloride (PHMG). Single samples showed contamination with DEP (275-1269 mg/l) and PHMG (515 mg/l) above levels of toxicological concern. Our detailed chemical analysis of Russian alcohols showed that the composition of vodka, samogon and medicinal alcohols generally did not raise major public health concerns other than for ethanol. It was shown, however, that concentration levels of DEP and PHMG in some surrogate alcohols make these samples unfit for human consumption as even moderate drinking would exceed acceptable daily intakes.

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  • While there have been some instances where ingredients of unrecorded alcohol have been found which could cause liver problems over and above the impact of ethanol, these instances are limited.

    “While there have been some instances where ingredients of unrecorded alcohol have been found which could cause liver problems over and above the impact of ethanol 288, 289 these instances are limited, and the overall conclusion of relevant reviews has been that there is not sufficient evidence to link a sizable portion of liver cirrhosis mortality to unrecorded alcohol (290, 291; see also 292).”

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Research works printed but not linked: 3

  1. Nuzhnyi V Haworth A Simpson R Chemical composition, toxic, and organoleptic properties of noncommercial alcohol samples Moonshine Markets. Issues in unrecorded alcohol beverage production and consumption 2004 New York Brunner-Routledge 177 199
  2. Yushkov BG Sencov VG Bogdanov SI Tyumenceva NV Medvedeva SU Danilova IG Gafarova RK Gette IF Krohina NB Zobnini UV Zilberman FA Influence of polyhexamethyleneguanidine hydrochloride and CCl4 on structured-functional dates of the rat's liver in process of the shaping sharp hepatitis toxic genesis Vest Ural Med Nauki 2011 4 114 118
  3. Zaigraev G Haworth A Simpson R The Russian model of noncommercial alcohol composition Moonshine market: issues in unrecorded alcohol beverage production and consumption 2004 New York and Hove Brunner-Routledge 31 40

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Authors
Solodun, Y., Monakhova, Y., Kuballa, T., Samokhvalov, A., Rehm, J., & Lachenmeier, D.
Affiliations
  • Saratov State University (RU)
  • Chemisches und Veterinäruntersuchungsamt Karlsruhe (DE)
  • Centre for Addiction and Mental Health (CA)
Corresponding author
Lachenmeier, Dirk
Venue
Interdisciplinary Toxicology
Published
2011-12-01
Volume
4
Issue
4
Pages
198-205
ISSN
  • 1337-6853 (ISSN-L)
  • 1337-9569
OpenAlex
W2131437411
Cited by
69
References
51
Citations by year
2024: 4 · 2023: 2 · 2022: 2 · 2021: 3 · 2020: 4 · 2019: 6 · 2018: 6 · 2017: 8 · 2016: 6 · 2015: 6 · 2014: 7 · 2013: 12 · 2012: 3
FWCI
8.99
Type
journal article
Language
en
Open access
Licence
cc-by-nc-nd
Locations
  • Interdisciplinary Toxicology (publishedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • Zenodo (CERN European Organization for Nuclear Research) (submittedVersion, cc-by)
Funders
Deutscher Akademischer Austauschdienst
Topics
  • Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Forensic Toxicology and Drug Analysis
  • Health Sciences › Medicine › Pathology and Forensic Medicine › Alcohol Consumption and Health Effects
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
unrecorded alcohol, diethyl phthalate, ethyl carbamate, methanol, acetaldehyde, higher alcohols, toxicological evaluation, acceptable daily intake

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