The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Fibroblasts and myofibroblasts in renal fibrosis
Open accessAbstract
Interstitial fibrosis, associated with extensive accumulation of extracellular matrix constituents in the cortical interstitium, is directly correlated to progression of renal disease. The earliest histological marker of this progression is the accumulation in the interstitium of fibroblasts with the phenotypic appearance of myofibroblasts. These myofibroblasts are contractile cells that express alpha smooth muscle actin and incorporate it into intracellular stress fibres. Although fibroblasts are histologically visible in normal kidneys, there are relatively few of them and proximal tubular epithelial cells predominate. In progressive disease, however, the interstitium becomes filled with myofibroblasts. In this review, we will examine the phenotype and function of fibroblasts and myofibroblasts in the cortical interstitium and the processes that may modulate them.
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Cites
Myofibroblasts and mechano-regulation of connective tissue remodelling
Tomasek, J. J., Gabbiani, G., Hinz, B., Chaponnier, C., & Brown, R. A. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm809 · Cited by 4,290
Formation and function of the myofibroblast during tissue repair
Hinz, B. (2007) · Journal of Investigative Dermatology · doi:10.1038/sj.jid.5700613 · Cited by 1,658
Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
Gabbiani, G., Ryan, G. B., & Majno, G. (1971) · Experientia · doi:10.1007/bf02147594 · Cited by 1,485
Peripheral Blood Fibrocytes: Differentiation Pathway and Migration to Wound Sites
Abe, R., Donnelly, S. C., Peng, T., Bucala, R., & Metz, C. N. (2001) · The Journal of Immunology · doi:10.4049/jimmunol.166.12.7556 · Cited by 967
Perspective Article: Tissue repair, contraction, and the myofibroblast
Desmoulière, A., Chaponnier, C., & Gabbiani, G. (2005) · Wound Repair and Regeneration · doi:10.1111/j.1067-1927.2005.130102.x · Cited by 892
Serini, G., Bochaton-Piallat, M.-L., Ropraz, P., Geinoz, A., Borsi, L., Zardi, L., & Gabbiani, G. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.142.3.873 · Cited by 847
Hinz, B. (2009) · Current Rheumatology Reports · doi:10.1007/s11926-009-0017-1 · Cited by 373
Myofibroblast development is characterized by specific cell-cell adherens junctions
Hinz, B., Pittet, P., Smith-Clerc, J., Chaponnier, C., & Meister, J.-J. (2004) · Molecular Biology of the Cell · doi:10.1091/mbc.e04-05-0386 · Cited by 231 · cited 1×
“This process is poorly understood, but the importance of mechanical factors is becoming increasingly apparent (Hinz & Gabbiani 2003a,b, Hinz et al. 2004; Tomasek et al. 2002, 2006) (Figure 1).”
BackgroundMoulin, V., Larochelle, S., Langlois, C., Thibault, I., Lopez‐Vallé, C. A., & Roy, M. (2004) · Journal of Cellular Physiology · doi:10.1002/jcp.10415 · Cited by 144
Cited by
Cellular and molecular mechanisms of renal fibrosis
Liu, Y. (2011) · Nature Reviews Nephrology · doi:10.1038/nrneph.2011.149 · Cited by 1,446
The myofibroblast matrix: implications for tissue repair and fibrosis
Klingberg, F., Hinz, B., & White, E. S. (2013) · The Journal of Pathology · doi:10.1002/path.4104 · Cited by 776
Transforming growth factor‐β in stem cells and tissue homeostasis
Xu, X., Zheng, L., Yuan, Q., Zhen, G., Crane, J. L., Zhou, X., & Cao, X. (2018) · Bone Research · doi:10.1038/s41413-017-0005-4 · Cited by 414
the Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium, Der, E., Suryawanshi, H., Morozov, P., Kustagi, M., Goilav, B., Ranabothu, S., Izmirly, P., Clancy, R., Belmont, H. M., et al. (2019) · Nature Immunology · doi:10.1038/s41590-019-0386-1 · Cited by 403
NOGUEIRA, A., PIRES, M. J., & OLIVEIRA, P. A. (2017) · In Vivo · doi:10.21873/invivo.11019 · Cited by 382
Metadata
- Authors
- Meran, S., & Steadman, R.
- Venue
- International Journal of Experimental Pathology
- Publisher
- Wiley
- Published
- 2011-02-28
- Volume
- 92
- Issue
- 3
- Pages
- 158-167
- ISSN
- 0959-9673 (ISSN-L)
- OpenAlex
- W1684625763
- Cited by
- 346
- References
- 9
- FWCI
- 14.25
- Type
- journal article
- Language
- en
- Open access
- green
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