The DOI matches its Crossref record; 67 of the 67 references it cites were found in a registry or an index.
Serotonin: a review
Open accessAbstract
5‐Hydroxytryptamine, or serotonin, is a biogenic amine most noted for its role as a neurotransmitter. Manipulation of serotonin in animal models was used as a tool for studying its role in humans. Through such research serotonin has been shown to modulate gastrointestinal motility, peripheral vascular tone, cerebral vascular tone, and platelet function and has been implicated in the pathophysiology of mood disorders, emesis, migraine, irritable bowel syndrome (IBS), and pulmonary and systemic hypertension. The knowledge gained is being directly applied back to animals in research on drugs that manipulate the serotonergic system in dogs and cats. Increasing use and availability of drugs that manipulate the serotonergic system has created a circumstance through which a novel toxicity was discovered in both humans and animals. Serotonin Syndrome describes the clinical picture seen in humans and animals with serotonin toxicity. This paper provides a review the physiology of serotonin and its involvement in the pathophysiologic mechanisms of various conditions, including the Serotonin Syndrome.
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Cites
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Cited by
Serotonin, tryptophan metabolism and the brain-gut-microbiome axis
O’Mahony, S. M., Clarke, G., Borre, Y. E., Dinan, T. G., & Cryan, J. F. (2015) · Behavioural Brain Research · doi:10.1016/j.bbr.2014.07.027 · Cited by 2,012
Tryptophan metabolism and gut-brain homeostasis
Roth, W., Zadeh, K., Vekariya, R., Ge, Y., & Mohamadzadeh, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22062973 · Cited by 519
Circadian rhythm dysregulation and restoration: the role of melatonin
Vasey, C., McBride, J., & Penta, K. (2021) · Nutrients · doi:10.3390/nu13103480 · Cited by 351
Serotonin stimulates secretion of exosomes from microglia cells
Glebov, K., Löchner, M., Jabs, R., Lau, T., Merkel, O., Schloss, P., Steinhäuser, C., & Walter, J. (2015) · Glia · doi:10.1002/glia.22772 · Cited by 221
Role of Gut Microbiome in Autism Spectrum Disorder and Its Therapeutic Regulation
Taniya, M. A., Chung, H.-J., Al Mamun, A., Alam, S., Aziz, M. A., Emon, N. U., Islam, M. M., Hong, S.-T. S., Podder, B. R., Ara Mimi, A., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.915701 · Cited by 207
Metadata
- Authors
- MOHAMMAD‐ZADEH, L. F., MOSES, L., & GWALTNEY‐BRANT, S. M.
- Venue
- Journal of Veterinary Pharmacology and Therapeutics
- Publisher
- Wiley
- Published
- 2008-04-17
- Volume
- 31
- Issue
- 3
- Pages
- 187-199
- ISSN
- 0140-7783 (ISSN-L)
- 1365-2885
- OpenAlex
- W1996889745
- Cited by
- 522
- References
- 67
- FWCI
- 4.27
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
