The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.
A review of applications of tea tree oil in dermatology
Abstract
Tea tree oil (TTO) is an essential oil, steam‐distilled from the Australian native plant, Melaleuca alternifolia. It has a minimum content of terpinen‐4‐ol and a maximum content of 1, 8‐cineole. Terpinen‐4‐ol is a major TTO component which exhibits strong antimicrobial and anti‐inflammatory properties. Tea tree oil exerts antioxidant activity and has been reported to have broad‐spectrum antimicrobial activity against bacterial, viral, fungal, and protozoal infections affecting skin and mucosa. Several studies have suggested the uses of TTO for the treatment of acne vulgaris, seborrheic dermatitis, and chronic gingivitis. It also accelerates the wound healing process and exhibits anti‐skin cancer activity. This review opens up new horizons for dermatologists in the use of this herbal agent.
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“Alternative therapies have been reported as well, such as tea tree oil [40,41].”
From Seborrheic Dermatitis and Dandruff: A Comprehensive Review (2015) · cites this paper as [40]
In the citing paper
“According to the Oxford evidence hierarchy, this would fall under the category of Level IV evidence. Additionally, the paper could benefit from a more critical analysis of the potential risks and side effects associated with the use of tea tree oil in dermatology.”
From Cosmeceuticals in photoaging: A review. (2024) · cites this paper as [14]
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Liberati, A., Altman, D. G., Tetzlaff, J., Mulrow, C., Gøtzsche, P. C., Ioannidis, J. P. A., Clarke, M., Devereaux, P. J., Kleijnen, J., & Moher, D. (2009) · Italian Journal of Public Health · doi:10.2427/5768 · Cited by 3,374
Melaleuca alternifolia (Tea Tree) Oil: a Review of Antimicrobial and Other Medicinal Properties
Carson, C. F., Hammer, K. A., & Riley, T. V. (2006) · Clinical Microbiology Reviews · doi:10.1128/cmr.19.1.50-62.2006 · Cited by 1,429
A review of the toxicity of Melaleuca alternifolia (tea tree) oil
Hammer, K. A., Carson, C. F., Riley, T. V., et al. (2005) · Food and Chemical Toxicology · doi:10.1016/j.fct.2005.09.001 · Cited by 313
A comparative study of tea‐tree oil versus benzoylperoxide in the treatment of acne
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In vitro and in vivo killing of ocular Demodex by tea tree oil
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“…is used in traditional medicine to treat skin infections, insect bites, bruises, vertigo, convulsions, toothache, rheumatism, colds, and flu (Pazyar et al. 2013; Usia et al. 2006 ; Greay et al. 2010 ), and TTO is thought to be effective in treating diseases caused by bacteria, fungi, and…”
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“Extracted from the Australian plant Melaleuca alternifolia, tea tree oil (TTO) contains nearly a hundred compounds, primarily terpene hydrocarbons with notable antimicrobial properties [2].”
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“The histopathological evaluation of treated wounded tissues, on Day 21 revealed a distorted epidermis with pure shikonin scaffolds (SK-NF) and MKTD, partial regeneration and hyperkeratosis of epidermis in blank formulations containing TTo (B-NE-gel; B-NE-NF), complete creation of epidermis with ST-NE-gel with evidence…”
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Metadata
- Authors
- Pazyar, N., Yaghoobi, R., Bagherani, N., & Kazerouni, A.
- Affiliations
- Ahvaz Jundishapur University of Medical Sciences (IR)
- Corresponding author
- Pazyar, Nader
- Venue
- International Journal of Dermatology
- Publisher
- Wiley
- Published
- 2012-09-24
- Volume
- 52
- Issue
- 7
- Pages
- 784-790
- ISSN
- 0011-9059 (ISSN-L)
- 1365-4632
- OpenAlex
- W2016711385
- Semantic Scholar
- 8af9fc3638195427a56def3e97838ca793b73aea
- Cited by
- 252
- References
- 46
- Citations by year
- 2026: 14 · 2025: 23 · 2024: 23 · 2023: 32 · 2022: 37 · 2021: 31 · 2020: 23 · 2019: 15 · 2018: 9 · 2017: 14 · 2016: 8 · 2015: 12 · 2014: 7 · 2013: 4
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- International Journal of Dermatology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Essential Oils and Antimicrobial Activity
- Health Sciences › Medicine › Dermatology › Acne and Rosacea Treatments and Effects
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- tea tree oil, Melaleuca alternifolia, terpinen-4-ol, 1,8-cineole, antimicrobial activity, anti-inflammatory activity, antioxidant activity, acne, seborrheic dermatitis, chronic gingivitis, wound healing, anticancer activity, herbal medicine, skin infections
- MeSH terms
- Anti-Infective Agents, Local, Humans, Skin Diseases, Tea Tree Oil
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