The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
Puberty as a highly vulnerable developmental period for the consequences of cannabis exposure
Abstract
During puberty, neuronal maturation of the brain, which began during perinatal development, is completed such that the behavioral potential of the adult organism can be fully achieved. These maturational events and processes of reorganization are needed for the occurrence of adult behavioral performance but simultaneously render the organism highly susceptible to perturbations, such as exposure to psychoactive drugs, during this critical developmental time span. Considering the variety of maturational processes occurring in the endocannabinoid system during this critical period, it is not surprising that the still‐developing brain might by highly susceptible to cannabis exposure. Emerging evidence from human studies and animal research demonstrates that an early onset of cannabis consumption might have lasting consequences on cognition, might increase the risk for neuropsychiatric disorders, promote further illegal drug intake and increase the likelihood of cannabis dependence. These findings suggest that young people represent a highly vulnerable cannabis consumer group and that they run a higher risk than adult consumers of suffering from adverse consequences from cannabinoid exposure. The aim of the present review is to provide an overview over the possible deleterious residual cannabinoid effects during critical periods of postnatal maturation and to offer a more precise delineation of the vulnerable time window for cannabinoid exposure.
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Self-citation
Metadata
- Authors
- Schneider, M.
- Venue
- Addiction Biology
- Publisher
- Wiley
- Published
- 2008-06
- Volume
- 13
- Issue
- 2
- Pages
- 253-263
- ISSN
- 1355-6215 (ISSN-L)
- 1369-1600
- OpenAlex
- W2130687867
- Cited by
- 316
- References
- 95
- FWCI
- 15.11
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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