Cited by 130Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal SignalingDevelopmental Biology and Gene Regulation

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Emerging topics in Reelin function

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Förster, Eckart, Bock, Hans H., Herz, Joachim, Chai, Xuejun, Frotscher, Michael, Zhao, Shanting·2010·European Journal of Neuroscience

DOI 10.1111/j.1460-9568.2010.07222.xPMC PMC2942760

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Abstract

Reelin signalling in the early developing cortex regulates radial migration of cortical neurons. Later in development, Reelin promotes maturation of dendrites and dendritic spines. Finally, in the mature brain, it is involved in modulating synaptic function. In recent years, efforts to identify downstream signalling events induced by binding of Reelin to lipoprotein receptors led to the characterization of novel components of the Reelin signalling cascade. In the present review, we first address distinct functions of the Reelin receptors Apoer2 and Vldlr in cortical layer formation, followed by a discussion on the recently identified downstream effector molecule n‐cofilin, involved in regulating actin cytoskeletal dynamics required for coordinated neuronal migration. Next, we discuss possible functions of the recently identified Reelin–Notch signalling crosstalk, and new aspects of the role of Reelin in the formation of the dentate radial glial scaffold. Finally, progress in characterizing the function of Reelin in modulating synaptic function in the adult brain is summarized. The present review has been inspired by a session entitled ‘Functions of Reelin in the developing and adult hippocampus’, held at the Spring Hippocampal Research Conference in Verona/Italy, June 2009.

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A protein related to extracellular matrix proteins deleted in the mouse mutant reeler
D'Arcangelo, G., G. Miao, G., Chen, S.-C., Scares, H. D., Morgan, J. I., & Curran, T. (1995) · Nature · doi:10.1038/374719a0 · Cited by 1,748
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Regulation of NMDA receptor trafficking by amyloid-β
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Laurén, J., Gimbel, D. A., Nygaard, H. B., Gilbert, J. W., & Strittmatter, S. M. (2009) · Nature · doi:10.1038/nature07761 · Cited by 1,560
Regulation of actin dynamics through phosphorylation of cofilin by LIM-kinase
Arber, S., Barbayannis, F. A., Hanser, H., Schneider, C., Stanyon, C. A., Bernard, O., & Caroni, P. (1998) · Nature · doi:10.1038/31729 · Cited by 1,426
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Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., & Herz, J. (1999) · Cell · doi:10.1016/s0092-8674(00)80782-5 · Cited by 1,261
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Malatesta, P., Hartfuss, E., & Götz, M. (2000) · Development · doi:10.1242/dev.127.24.5253 · Cited by 1,157
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Hsieh, H., Boehm, J., Sato, C., Iwatsubo, T., Tomita, T., Sisodia, S., & Malinow, R. (2006) · Neuron · doi:10.1016/j.neuron.2006.10.035 · Cited by 1,042
Proteins of the ADF/Cofilin Family: Essential Regulators of Actin Dynamics
Bamburg, J. R. (1999) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.15.1.185 · Cited by 1,015

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Authors: Förster, E., Bock, H. H., Herz, J., Chai, X., Frotscher, M., & Zhao, S.
Affiliations: Universität Hamburg (DE)
University of Freiburg (DE)
Corresponding author: Förster, Eckart
ORCID: Bock, Hans H.
Herz, Joachim
Chai, Xuejun
Frotscher, Michael
Zhao, Shanting
Venue: European Journal of Neuroscience
Publisher: Wiley
Published: 2010-04-30
Volume: 31
Issue: 9
Pages: 1511-1518
ISSN: 0953-816X (ISSN-L)
1460-9568
DOI: 10.1111/j.1460-9568.2010.07222.x
PMC: PMC2942760
OpenAlex: W1795146795
Cited by: 130
References: 109
Citations by year: 2026: 2 · 2025: 2 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 6 · 2020: 5 · 2019: 5 · 2018: 5 · 2017: 8 · 2016: 14 · 2015: 12 · 2014: 8 · 2013: 20 · 2012: 12
FWCI: 1.28
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Licence: onlinelibrary.wiley.com/termsAndConditions#vor (vor)
Locations: European Journal of Neuroscience (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
Funders: Deutsche Forschungsgemeinschaft
National Heart, Lung, and Blood Institute (R01HL063762, R37HL063762, P01HL020948)
National Institute of Neurological Disorders and Stroke (RC1NS068697, R01NS043408)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
Keywords: cortical development, radial neuronal migration, cortical lamination, dendritic spine maturation, synaptic function, ApoER2, VLDLR, actin cytoskeleton, dentate gyrus, hippocampus, lipoprotein receptors
MeSH terms: Reelin Protein, Animals, Cytoskeleton, Humans, Models, Neurological, Nerve Tissue Proteins, Neuroglia, Neurons, Receptors, Cell Surface, Serine Endopeptidases, Cell Adhesion Molecules, Neuronal, Extracellular Matrix Proteins

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