Extracellular Matrix: Functions in the Nervous System

Barros, C. S.; Franco, S. J.; Muller, U.

doi:10.1101/cshperspect.a005108

Cited by 506Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal SignalingNeuroscience and Neuropharmacology Research

Extracellular Matrix: Functions in the Nervous System

Open access

Barros, C. S., Franco, S. J., Muller, U.·2011·Cold Spring Harbor Perspectives in Biology

DOI 10.1101/cshperspect.a005108PMC PMC3003458

Open this paper in CoChat — free account Open PDF

Abstract

An astonishing number of extracellular matrix glycoproteins are expressed in dynamic patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia express receptors that mediate interactions with specific extracellular matrix molecules. Functional studies in vitro and genetic studies in mice have provided evidence that the extracellular matrix affects virtually all aspects of nervous system development and function. Here we will summarize recent findings that have shed light on the specific functions of defined extracellular matrix molecules on such diverse processes as neural stem cell differentiation, neuronal migration, the formation of axonal tracts, and the maturation and function of synapses in the peripheral and central nervous system.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1101/cshperspect.a005108

Cites

327 of 327 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The neural ECM differs from non-neural ECM by having low fibrous proteins and high GAGs and PGs.
“the neural ECM, in contrast, is composed of low levels of fibrous proteins, high amount of GAGs (Novak and Kaye, 2000) as well as PGs”
From Perineuronal nets and schizophrenia: The importance of neuronal coatings (2014) · cites this paper as Barros et al., 2011

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

2 retracted

RETRACTED: A Ligand-Gated Association between Cytoplasmic Domains of UNC5 and DCC Family Receptors Converts Netrin-Induced Growth Cone Attraction to Repulsion
Hong, K., Hinck, L., Nishiyama, M., Poo, M.-M., Tessier‐Lavigne, M., & Stein, E. (1999) · Cell · doi:10.1016/s0092-8674(00)80804-1 · Cited by 684 · see citing works
Retracted
RETRACTED: Hierarchical Organization of Guidance Receptors: Silencing of Netrin Attraction by Slit Through a Robo/DCC Receptor Complex
Stein, E., & Tessier-Lavigne, M. (2001) · Science · doi:10.1126/science.1058445 · Cited by 601 · see citing works
Retracted
Regeneration beyond the glial scar
Silver, J., & Miller, J. H. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1326 · Cited by 3,090 · see citing works
Chondroitinase ABC promotes functional recovery after spinal cord injury
Bradbury, E. J., Moon, L. D. F., Popat, R. J., King, V. R., Bennett, G. S., Patel, P. N., Fawcett, J. W., & McMahon, S. B. (2002) · Nature · doi:10.1038/416636a · Cited by 2,357 · see citing works
Laminin–a glycoprotein from basement membranes
Timpl, R., Rohde, H., Robey, P. G., Rennard, S. I., Foidart, J. M., & Martin, G. R. (1979) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)83607-4 · Cited by 1,780 · see citing works
Thrombospondins are astrocyte-secreted proteins that promote CNS synaptogenesis
Christopherson, K. S., Ullian, E. M., Stokes, C. C. A., Mullowney, C. E., Hell, J. W., Agah, A., Lawler, J., Mosher, D. F., Bornstein, P., & Barres, B. A. (2005) · Cell · doi:10.1016/j.cell.2004.12.020 · Cited by 1,688 · see citing works
Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex
Pizzorusso, T., Medini, P., Berardi, N., Chierzi, S., Fawcett, J. W., & Maffei, L. (2002) · Science · doi:10.1126/science.1072699 · Cited by 1,679 · see citing works
The development of neural stem cells
Temple, S. (2001) · Nature · doi:10.1038/35102174 · Cited by 1,494 · see citing works
Control of Synapse Number by Glia
Ullian, E. M., Sapperstein, S. K., Christopherson, K. S., & Barres, B. A. (2001) · Science · doi:10.1126/science.291.5504.657 · Cited by 1,380 · see citing works
Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2
Trommsdorff, M., Gotthardt, M., Hiesberger, T., Shelton, J., Stockinger, W., Nimpf, J., Hammer, R. E., Richardson, J. A., & Herz, J. (1999) · Cell · doi:10.1016/s0092-8674(00)80782-5 · Cited by 1,261 · see citing works
Deleted in Colorectal Cancer (DCC) Encodes a Netrin Receptor
Keino‐Masu, K., Masu, M., Hinck, L., Leonardo, E. D., Chan, S. S.-Y., Culotti, J. G., & Tessier‐Lavigne, M. (1996) · Cell · doi:10.1016/s0092-8674(00)81336-7 · Cited by 1,013 · see citing works
Neurexins Induce Differentiation of GABA and Glutamate Postsynaptic Specializations via Neuroligins
Graf, E. R., Zhang, X., Jin, S., Linhoff, M. W., & Craig, A. M. (2004) · Cell · doi:10.1016/j.cell.2004.11.035 · Cited by 1,001 · see citing works
Slit Is the Midline Repellent for the Robo Receptor in Drosophila
Kidd, T., Bland, K. S., & Goodman, C. S. (1999) · Cell · doi:10.1016/s0092-8674(00)80589-9 · Cited by 953 · see citing works
The unc-5, unc-6, and unc-40 genes guide circumferential migrations of pioneer axons and mesodermal cells on the epidermis in C. elegans
Hedgecock, E. M., Culotti, J. G., & Hall, D. H. (1990) · Neuron · doi:10.1016/0896-6273(90)90444-k · Cited by 935 · see citing works
Oligodendrocytes: biology and pathology
Bradl, M., & Lassmann, H. (2010) · Acta Neuropathologica · doi:10.1007/s00401-009-0601-5 · Cited by 933 · see citing works
Defective Neuromuscular Synaptogenesis in Agrin-Deficient Mutant Mice
Gautam, M., Noakes, P. G., Moscoso, L. M., Rupp, F., Scheller, R. H., Merlie, J. P., & Sanes, J. R. (1996) · Cell · doi:10.1016/s0092-8674(00)81253-2 · Cited by 933 · see citing works
Gabapentin Receptor α2δ-1 Is a Neuronal Thrombospondin Receptor Responsible for Excitatory CNS Synaptogenesis
Eroglu, Ç., Allen, N. J., Susman, M. W., O'Rourke, N. A., Park, C. Y., Özkan, E., Chakraborty, C., Mulinyawe, S. B., Annis, D. S., Huberman, A. D., et al. (2009) · Cell · doi:10.1016/j.cell.2009.09.025 · Cited by 893 · see citing works
The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons
Ogawa, M., Miyata, T., Nakajimat, K., Yagyu, K., Seike, M., Ikenaka, K., Yamamoto, H., & Mikoshibat, K. (1995) · Neuron · doi:10.1016/0896-6273(95)90329-1 · Cited by 889 · cited 2× · see citing works
“Reelin has variably been proposed to be a chemoattractant (Gilmore and Herrup 2000), repellent (Ogawa et al. 1995; Schiffmann et al. 1997), stop (Sheppard and Pearlman 1997), or detachment (Sheppard and Pearlman 1997; Dulabon et al. 2000; Sanada et al. 2004) signal for migrating neurons.”
Background
Autosomal recessive lissencephaly with cerebellar hypoplasia is associated with human RELN mutations
Hong, S. E., Shugart, Y. Y., Huang, D. T.-C., Shahwan, S. A., Grant, P. E., Hourihane, J. O., Martin, N. D. T., & Walsh, C. A. (2000) · Nature Genetics · doi:10.1038/79246 · Cited by 878 · see citing works
GSK-3β Regulates Phosphorylation of CRMP-2 and Neuronal Polarity
Yoshimura, T., Kawano, Y., Arimura, N., Kawabata, S., Kikuchi, A., & Kaibuchi, K. (2005) · Cell · doi:10.1016/j.cell.2004.11.012 · Cited by 877 · see citing works
Reelin Is a Ligand for Lipoprotein Receptors
D'Arcangelo, G., Homayouni, R., Keshvara, L., Rice, D. S., Sheldon, M., & Curran, T. (1999) · Neuron · doi:10.1016/s0896-6273(00)80860-0 · Cited by 808 · cited 5× · see citing works
“Reelin binds to the lipoprotein receptors ApoER2 and VLDLR (D’Arcangelo et al. 1999), which are expressed by migrating neurons and RGCs (Luque et al. 2003).”
BackgroundInfluential
Post-translational disruption of dystroglycan–ligand interactions in congenital muscular dystrophies
Michele, D. E., Barresi, R., Kanagawa, M., Saito, F., Cohn, R. D., Satz, J. S., Dollar, J., Nishino, I., Kelley, R. I., Somer, H., et al. (2002) · Nature · doi:10.1038/nature00837 · Cited by 779 · see citing works
Perineuronal Nets Protect Fear Memories from Erasure
Gogolla, N., Caroni, P., Lüthi, A., & Herry, C. (2009) · Science · doi:10.1126/science.1174146 · Cited by 760 · see citing works
Extracellular Matrix Molecules And Their Receptors: Functions In Neural Development
Reichardt, L. F., & Tomaselli, K. J. (1991) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.14.030191.002531 · Cited by 750 · see citing works
Muscular Dystrophy and Neuronal Migration Disorder Caused by Mutations in a Glycosyltransferase, POMGnT1
Yoshida, A., Kobayashi, K., Manya, H., Taniguchi, K., Kano, H., Mizuno, M., Inazu, T., Mitsuhashi, H., Takahashi, S., Takeuchi, M., et al. (2001) · Developmental Cell · doi:10.1016/s1534-5807(01)00070-3 · Cited by 706 · see citing works
Supramolecular assembly of basement membranes
Timpl, R., & Brown, J. C. (1996) · BioEssays · doi:10.1002/bies.950180208 · Cited by 701 · see citing works
Two modes of radial migration in early development of the cerebral cortex
Nadarajah, B., Brunstrom, J. E., Grutzendler, J., Wong, R., & Pearlman, A. L. (2001) · Nature Neuroscience · doi:10.1038/83967 · Cited by 689 · see citing works
Mutations in the O-Mannosyltransferase Gene POMT1 Give Rise to the Severe Neuronal Migration Disorder Walker-Warburg Syndrome
de Bernabé, D. B.-V., Currier, S., Steinbrecher, A., Celli, J., van Beusekom, E., van der Zwaag, B., Kayserili, H., Merlini, L., Chitayat, D. A., Dobyns, W. B., et al. (2002) · The American Journal of Human Genetics · doi:10.1086/342975 · Cited by 683 · see citing works
Lrp4 is a receptor for Agrin and forms a complex with MuSK
Kim, N., Stiegler, A. L., Cameron, T. O., Hallock, P. T., Gomez, A. M., Huang, J. H., Hubbard, S. R., Dustin, M. L., & Burden, S. J. (2008) · Cell · doi:10.1016/j.cell.2008.10.002 · Cited by 676 · see citing works
The bright side of the glial scar in CNS repair
Rolls, A., Shechter, R., & Schwartz, M. (2009) · Nature Reviews Neuroscience · doi:10.1038/nrn2591 · Cited by 674 · see citing works
The extracellular matrix: an active or passive player in fibrosis?
Wight, T. N., & Potter‐Perigo, S. (2011) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00132.2011 · Cited by 669 · see citing works
Mechanisms of axon ensheathment and myelin growth
Sherman, D. L., & Brophy, P. J. (2005) · Nature Reviews Neuroscience · doi:10.1038/nrn1743 · Cited by 668 · see citing works
Agrin Acts via a MuSK Receptor Complex
Glass, D. J., Bowen, D. C., Stitt, T. N., Radziejewski, C. H., Bruno, J., RYAN, T. E., Gies, D. R., Shah, S., Mattsson, K., Burden, S. J., et al. (1996) · Cell · doi:10.1016/s0092-8674(00)81252-0 · Cited by 662 · see citing works
Patterns of neuronal migration in the embryonic cortex
Kriegstein, A. R., & Noctor, S. C. (2004) · Trends in Neurosciences · doi:10.1016/j.tins.2004.05.001 · Cited by 648 · see citing works
Lecticans: organizers of the brain extracellular matrix
Yamaguchi, Y. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000690 · Cited by 642 · see citing works
Neocortical histogenesis in normal and reeler mice: A developmental study based upon [3H]thymidine autoradiography
Caviness, V. S. (1982) · Developmental Brain Research · doi:10.1016/0165-3806(82)90141-9 · Cited by 639 · see citing works
Proteoglycans in the Developing Brain: New Conceptual Insights for Old Proteins
Bandtlow, C. E., & Zimmermann, D. R. (2000) · Physiological Reviews · doi:10.1152/physrev.2000.80.4.1267 · Cited by 632 · see citing works
Mutations in the laminin α2–chain gene (LAMA2) cause merosin–deficient congenital muscular dystrophy
Helbling-Leclerc, A., Zhang, X., Topaloğlu, H., Cruaud, C., Tesson, F., Weissenbach, J., Tomé, F. M. S., Schwartz, K., Fardeau, M., Tryggvason, K., et al. (1995) · Nature Genetics · doi:10.1038/ng1095-216 · Cited by 631 · see citing works
Reelin and ApoE receptors cooperate to enhance hippocampal synaptic plasticity and learning
Weeber, E. J., Beffert, U., Jones, C., Christian, J. M., Förster, E., Sweatt, J. D., & Herz, J. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m205147200 · Cited by 623 · see citing works
Reelin Binds α3β1 Integrin and Inhibits Neuronal Migration
Dulabon, L., Olson, E. C., Taglienti, M. G., Eisenhuth, S., McGrath, B., Walsh, C. A., Kreidberg, J. A., & Anton, E. S. (2000) · Neuron · doi:10.1016/s0896-6273(00)00007-6 · Cited by 577 · see citing works
The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system
Galtrey, C. M., & Fawcett, J. W. (2007) · Brain Research Reviews · doi:10.1016/j.brainresrev.2006.09.006 · Cited by 575 · see citing works
Deletion of brain dystroglycan recapitulates aspects of congenital muscular dystrophy
Moore, S. A., Saito, F., Chen, J., Michele, D. E., Henry, M. D., Messing, A., Cohn, R. D., Ross, S. E., Westra, S., Williamson, R. A., et al. (2002) · Nature · doi:10.1038/nature00838 · Cited by 574 · see citing works
Regional and Cellular Patterns ofreelinmRNA Expression in the Forebrain of the Developing and Adult Mouse
Alcántara, S., Ruiz, M., D’Arcangelo, G., Ezan, F., de Lecea, L., Curran, T., Sotelo, C., & Soriano, E. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-19-07779.1998 · Cited by 568 · see citing works
Regeneration of CNS axons back to their target following treatment of adult rat brain with chondroitinase ABC
Moon, L. D. F., Asher, R. A., Rhodes, K. E., & Fawcett, J. W. (2001) · Nature Neuroscience · doi:10.1038/87415 · Cited by 563 · see citing works
β1-Class Integrins Regulate the Development of Laminae and Folia in the Cerebral and Cerebellar Cortex
Graus-Porta, D., Blaess, S., Senften, M., Littlewood-Evans, A., Damsky, C. H., Huang, Z., Orban, P. C., Klein, R., Schittny, J. C., & Müller, U. (2001) · Neuron · doi:10.1016/s0896-6273(01)00374-9 · Cited by 559 · see citing works
Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity
Frischknecht, R., Heine, M., Perrais, D., Seidenbecher, C. I., Choquet, D., & Gundelfinger, E. D. (2009) · Nature Neuroscience · doi:10.1038/nn.2338 · Cited by 554 · see citing works
Absence of Basement Membranes after Targeting the LAMC1 Gene Results in Embryonic Lethality Due to Failure of Endoderm Differentiation
Smyth, N. R., Vatansever, S., Murray, P. A., Meyer, M., Frie, C., Paulsson, M., & Edgar, D. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.144.1.151 · Cited by 551 · see citing works
Extracellular Matrix Molecules that Influence Neural Development
Sanes, J. R. (1989) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.12.030189.002423 · Cited by 532 · see citing works
LRP4 serves as a coreceptor of Agrin
Zhang, B., Luo, S., Wang, Q., Suzuki, T., Xiong, W. C., & Mei, L. (2008) · Neuron · doi:10.1016/j.neuron.2008.10.006 · Cited by 525 · see citing works
To build a synapse: signaling pathways in neuromuscular junction assembly
Wu, H., Xiong, W., & Mei, L. (2010) · Development · doi:10.1242/dev.038711 · Cited by 519 · see citing works
UNC-40, a C. elegans Homolog of DCC (Deleted in Colorectal Cancer), Is Required in Motile Cells Responding to UNC-6 Netrin Cues
Chan, S., Zheng, H., Su, M., Wilk, R., Killeen, M. T., Hedgecock, E. M., & Culotti, J. G. (1996) · Cell · doi:10.1016/s0092-8674(00)81337-9 · Cited by 503 · see citing works
Perineuronal nets: past and present
Celio, M. R., Spreafico, R., De Biasi, S., & Vitellaro-Zuccarello, L. (1998) · Trends in Neurosciences · doi:10.1016/s0166-2236(98)01298-3 · Cited by 497 · see citing works
Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2
Beffert, U., Weeber, E. J., Durudas, A., Qiu, S., Masiulis, I., Sweatt, J. D., Li, W.-P., Adelmann, G., Frotscher, M., Hammer, R. E., et al. (2005) · Neuron · doi:10.1016/j.neuron.2005.07.007 · Cited by 497 · see citing works
Growth-cone attraction to netrin-1 is converted to repulsion by laminin-1
Höpker, V. H., Shewan, D. A., Tessier‐Lavigne, M., Poo, M., & Holt, C. E. (1999) · Nature · doi:10.1038/43441 · Cited by 493 · see citing works
Injury-Induced Proteoglycans Inhibit the Potential for Laminin-Mediated Axon Growth on Astrocytic Scars
McKeon, R. J., Höke, A., & Silver, J. (1995) · Experimental Neurology · doi:10.1006/exnr.1995.1081 · Cited by 486 · see citing works
The Basement Membrane/Basal Lamina of Skeletal Muscle
Sanes, J. R. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.r200027200 · Cited by 471 · see citing works
Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain.
Bagri, A., Marín, O., Plump, A., Mak, J., Pleasure, S., Rubenstein, J., & Tessier-Lavigne, M. (2002) · Neuron · doi:10.1016/s0896-6273(02)00561-5 · Cited by 467 · see citing works
Extracellular matrix of the central nervous system: from neglect to challenge
Zimmermann, D. R., & Dours-Zimmermann, M. T. (2008) · Histochemistry and Cell Biology · doi:10.1007/s00418-008-0485-9 · Cited by 465 · see citing works
NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis
Chen, Z., Paquette, A. J., & Anderson, D. J. (1998) · Nature Genetics · doi:10.1038/2431 · Cited by 461 · see citing works
frazzled Encodes a Drosophila Member of the DCC Immunoglobulin Subfamily and Is Required for CNS and Motor Axon Guidance
Kolodziej, P. A., Timpe, L. C., Mitchell, K. J., Fried, S. R., Goodman, C. S., Jan, L. Y., & Jan, Y. N. (1996) · Cell · doi:10.1016/s0092-8674(00)81338-0 · Cited by 460 · see citing works
Binding of the G domains of laminin α1 and α2 chains and perlecan to heparin, sulfatides, α‐dystroglycan and several extracellular matrix proteins
Talts, J. F., Andac, Z., Göhring, W., Brancaccio, A., & Timpl, R. (1999) · The EMBO Journal · doi:10.1093/emboj/18.4.863 · Cited by 454 · see citing works
Aberrant differentiation of neuromuscular junctions in mice lacking s-laminin/laminin β2
Noakes, P. G., Gautam, M., Mudd, J. L., Sanes, J. R., & Merlie, J. P. (1995) · Nature · doi:10.1038/374258a0 · Cited by 453 · see citing works
Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: A structural prototype for diversity in integrin signaling
Calderwood, D., Fujioka, Y., de Pereda, J. M., García‐Álvarez, B., Nakamoto, T., Margolis, B. L., McGlade, C. J., Liddington, R., & Ginsberg, M. H. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.262791999 · Cited by 427 · see citing works
Reelin-induced tryosine phosphorylation of Disabled 1 during neuronal positioning
Howell, B. W., Herrick, T. M., & Cooper, J. A. (1999) · Genes & Development · doi:10.1101/gad.13.6.643 · Cited by 411 · see citing works
Identification of potential target genes for the neuron-restrictive silencer factor.
Schoenherr, C. J., Paquette, A. J., & Anderson, D. J. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.18.9881 · Cited by 406 · see citing works
Anatomical, Physiological and biochemical studies of the cerebellum from reeler mutant mouse
Mariani, J., Crépel, F., Mikoshiba, K., Changeux, J., & Sotelo, C. (1977) · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · doi:10.1098/rstb.1977.0121 · Cited by 398 · see citing works
F-spondin: A gene expressed at high levels in the floor plate encodes a secreted protein that promotes neural cell adhesion and neurite extension
Klar, A., Baldassare, M., & Jessell, T. M. (1992) · Cell · doi:10.1016/0092-8674(92)90121-r · Cited by 390 · see citing works
J1/tenascin is a repulsive substrate for central nervous system neurons
Faissner, A., & Kruse, J. (1990) · Neuron · doi:10.1016/0896-6273(90)90217-4 · Cited by 378 · see citing works
Reelin promotes hippocampal dendrite development through the VLDLR/ApoER2-Dab1 pathway
Niu, S., Renfro, A., Quattrocchi, C. C., Sheldon, M., & D'Arcangelo, G. (2004) · Neuron · doi:10.1016/s0896-6273(03)00819-5 · Cited by 375 · see citing works
A Critical Function for β-Amyloid Precursor Protein in Neuronal Migration Revealed by In Utero RNA Interference
Young-Pearse, T. L., Bai, J., Chang, R., Zheng, J. B., LoTurco, J. J., & Selkoe, D. J. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.4701-07.2007 · Cited by 369 · see citing works
Laminin is associated with the "neurite outgrowth-promoting factors" found in conditioned media.
Lander, A. D., Fujii, D. K., & Reichardt, L. F. (1985) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.82.7.2183 · Cited by 346 · see citing works
Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components
Carulli, D., Rhodes, K. E., Brown, D. J., Bonnert, T. P., Pollack, S. J., Oliver, K., Strata, P., & Fawcett, J. W. (2006) · Journal of Comparative Neurology · doi:10.1002/cne.20822 · Cited by 341 · see citing works
Regulation of Commissural Axon Pathfinding by Slit and its Robo Receptors
Dickson, B. J., & Gilestro, G. F. (2006) · Annual Review of Cell and Developmental Biology · doi:10.1146/annurev.cellbio.21.090704.151234 · Cited by 331 · see citing works
Conditional disruption of β1 integrin in Schwann cells impedes interactions with axons
Feltri, M. L., Porta, D. G., Previtali, S. C., Nodari, A., Migliavacca, B., Cassetti, A., Littlewood-Evans, A., Reichardt, L. F., Messing, A., Quattrini, A., et al. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200109021 · Cited by 325 · see citing works
Comm Sorts Robo to Control Axon Guidance at the Drosophila Midline
Keleman, K., Rajagopalan, S., Cleppien, D., Teis, D., Paiha, K., Huber, L. A., Technau, G. M., & Dickson, B. J. (2002) · Cell · doi:10.1016/s0092-8674(02)00901-7 · Cited by 321 · see citing works
Short- and Long-Range Repulsion by the Drosophila Unc5 Netrin Receptor
Keleman, K., & Dickson, B. J. (2001) · Neuron · doi:10.1016/s0896-6273(01)00505-0 · Cited by 314 · see citing works
β1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance
Campos, L. S., Leone, D. P., Relvas, J. B., Brakebusch, C., Fässler, R., Suter, U., & ffrench‐Constant, C. (2004) · Development · doi:10.1242/dev.01199 · Cited by 313 · see citing works
Generation of an environmental niche for neural stem cell development by the extracellular matrix molecule tenascin C
Garcion, E., Halilagic, A., Faissner, A., & ffrench‐Constant, C. (2004) · Development · doi:10.1242/dev.01202 · Cited by 309 · see citing works
Essential role of α6 integrins in cortical and retinal lamination
Georges‐Labouesse, E., Mark, M. P., Messaddeq, N., & Gansmüller, A. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70402-6 · Cited by 304 · see citing works
Still More Complexity in Mammalian Basement Membranes
Erickson, A., & Couchman, J. (2000) · Journal of Histochemistry & Cytochemistry · doi:10.1177/002215540004801001 · Cited by 303 · see citing works
Mutant glycosyltransferase and altered glycosylation of α-dystroglycan in the myodystrophy mouse
Grewal, P. K., Holzfeind, P. J., Bittner, R. E., & Hewitt, J. E. (2001) · Nature Genetics · doi:10.1038/88865 · Cited by 301 · see citing works
Reelin modulates NMDA receptor activity in cortical neurons
Chen, Y., Beffert, U., Ertunc, M., Tang, T.-S., Kavalali, E. T., Bezprozvanny, I., & Herz, J. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1951-05.2005 · Cited by 299 · see citing works
Dendritic Spine Dynamics Are Regulated by Monocular Deprivation and Extracellular Matrix Degradation
Oray, S., Majewska, A., & Sur, M. (2004) · Neuron · doi:10.1016/j.neuron.2004.12.001 · Cited by 296 · see citing works
A Critical Function of the Pial Basement Membrane in Cortical Histogenesis
Halfter, W. M., Dong, S., Yip, Y.-P., Willem, M., & Mayer, U. (2002) · Journal of Neuroscience · doi:10.1523/jneurosci.22-14-06029.2002 · Cited by 290 · see citing works
Cell-extracellular matrix interactions regulate neural differentiation of human embryonic stem cells
Ma, W., Tavakoli, T., Derby, E. G., Serebryakova, Y., Rao, M. S., & Mattson, M. P. (2008) · BMC Developmental Biology · doi:10.1186/1471-213x-8-90 · Cited by 283 · see citing works
Fyn Tyrosine Kinase Is a Critical Regulator of Disabled-1 during Brain Development
Arnaud, L., Ballif, B. A., Förster, E., & Cooper, J. A. (2003) · Current Biology · doi:10.1016/s0960-9822(02)01397-0 · Cited by 283 · see citing works
Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily
Crossin, K. L., & Krushel, L. A. (2000) · Developmental Dynamics · doi:10.1002/(sici)1097-0177(200006)218:2 · Cited by 283 · see citing works
Maturation and Maintenance of the Neuromuscular Synapse
Grady, R. M., Zhou, H. H., Cunningham, J. M., Henry, M. D., Campbell, K. P., & Sanes, J. R. (2000) · Neuron · doi:10.1016/s0896-6273(00)80894-6 · Cited by 281 · see citing works
Signaling Mechanisms Underlying Slit2-Induced Collapse of Xenopus Retinal Growth Cones
Piper, M., Anderson, R. B., Dwivedy, A., Weinl, C., van Horck, F., Leung, K.-M., Cogill, E., & Holt, C. E. (2006) · Neuron · doi:10.1016/j.neuron.2005.12.008 · Cited by 272 · see citing works
Expression of tenascin in the developing and adult cerebellar cortex
Bartsch, S., Bartsch, U., Dörries, U., Faissner, A., Weller, A., Ekblom, P., & Schachner, M. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-03-00736.1992 · Cited by 271 · see citing works
J1-160 and J1-180 are oligodendrocyte-secreted nonpermissive substrates for cell adhesion.
Pesheva, P., Spieß, E., & Schachner, M. (1989) · The Journal of Cell Biology · doi:10.1083/jcb.109.4.1765 · Cited by 270 · see citing works
Role of the extracellular matrix during neural crest cell migration
Perris, R., & Perissinotto, D. (2000) · Mechanisms of Development · doi:10.1016/s0925-4773(00)00365-8 · Cited by 269 · see citing works
Extracellular Matrix 2: Role of extracellular matrix molecules and their receptors in the nervous system
Venstrom, K. A., & Reichardt, L. F. (1993) · The FASEB Journal · doi:10.1096/fasebj.7.11.8370483 · Cited by 269 · see citing works
The Reelin signaling pathway promotes dendritic spine development in hippocampal neurons
Niu, S., Yabut, O., & D'Arcangelo, G. (2008) · The Journal of Neuroscience · doi:10.1523/jneurosci.1917-08.2008 · Cited by 266 · see citing works
Narp and NP1 Form Heterocomplexes that Function in Developmental and Activity-Dependent Synaptic Plasticity
Xu, D., Hopf, C., Reddy, R., Cho, R. W., Guo, L., Lanahan, A., Petralia, R. S., Wenthold, R. J., O'Brien, R. J., & Worley, P. (2003) · Neuron · doi:10.1016/s0896-6273(03)00463-x · Cited by 265 · see citing works
DSCAM Is a Netrin Receptor that Collaborates with DCC in Mediating Turning Responses to Netrin-1
Ly, A., Nikolaev, A. Y., Suresh, G., Zheng, Y., Tessier‐Lavigne, M., & Stein, E. (2008) · Cell · doi:10.1016/j.cell.2008.05.030 · Cited by 265 · see citing works
A synaptic laminin–calcium channel interaction organizes active zones in motor nerve terminals
Nishimune, H., Sanes, J. R., & Carlson, S. S. (2004) · Nature · doi:10.1038/nature03112 · Cited by 264 · see citing works
Laminin and the mechanism of neuronal outgrowth
Luckenbill‐Edds, L. (1997) · Brain Research Reviews · doi:10.1016/s0165-0173(96)00013-6 · Cited by 257 · see citing works
Netrins: beyond the brain
Cirulli, V., & Yebra, M. (2007) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2142 · Cited by 257 · see citing works
Endorepellin causes endothelial cell disassembly of actin cytoskeleton and focal adhesions through α2β1 integrin
Bix, G. J., Fu, J., González, E. M. G., Macro, L., Barker, A., Campbell, S., Zutter, M. M., Santoro, S. A., Kim, J. K., Höök, M., et al. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200401150 · Cited by 252 · see citing works
Alternative Splicing of the Robo3 Axon Guidance Receptor Governs the Midline Switch from Attraction to Repulsion
Chen, Z., Gore, B. B., Long, H., Ma, L., & Tessier‐Lavigne, M. (2008) · Neuron · doi:10.1016/j.neuron.2008.02.016 · Cited by 251 · see citing works
Unique Role of Dystroglycan in Peripheral Nerve Myelination, Nodal Structure, and Sodium Channel Stabilization
Saito, F., Moore, S. A., Barresi, R., Henry, M. D., Messing, A., Ross, S. E., Cohn, R. D., Williamson, R. A., Sluka, K. A., Sherman, D. L., et al. (2003) · Neuron · doi:10.1016/s0896-6273(03)00301-5 · Cited by 250 · see citing works
Mice Deficient for Tenascin-R Display Alterations of the Extracellular Matrix and Decreased Axonal Conduction Velocities in the CNS
Weber, P., Bartsch, U., Rasband, M. N., Czaniera, R., Lang, Y., Bluethmann, H., Margolis, R. U., Levinson, S. R., Shrager, P., Montag, D., et al. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-11-04245.1999 · Cited by 247 · see citing works
CNS integrins switch growth factor signalling to promote target-dependent survival
Colognato, H., Baron, W., Avellana‐Adalid, V., Relvas, J. B., Evercooren, A. B., Georges‐Labouesse, E., & ffrench‐Constant, C. (2002) · Nature Cell Biology · doi:10.1038/ncb865 · Cited by 246 · see citing works
Embryonic neural retinal cell response to extracellular matrix proteins: developmental changes and effects of the cell substratum attachment antibody (CSAT).
Hall, D. E., Neugebauer, K. M., & Reichardt, L. F. (1987) · The Journal of Cell Biology · doi:10.1083/jcb.104.3.623 · Cited by 246 · see citing works
Regulation of human neural precursor cells by laminin and integrins
Flanagan, L. A., Rebaza, L. M., Derzic, S., Schwartz, P. H., & Monuki, E. S. (2006) · Journal of Neuroscience Research · doi:10.1002/jnr.20778 · Cited by 243 · see citing works
Molecular domains of myelinated axons.
Peles, E., & Salzer, J. (2000) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00122-7 · Cited by 242 · see citing works
Moving away from the midline: new developments for Slit and Robo
Ypsilanti, A., Zagar, Y., & Chédotal, A. (2010) · Development · doi:10.1242/dev.044511 · Cited by 242 · see citing works
Distinct Target-Derived Signals Organize Formation, Maturation, and Maintenance of Motor Nerve Terminals
Fox, M. A., Sanes, J. R., Borza, D., Eswarakumar, V. P., Fässler, R., Hudson, B. G., John, S. W. M., Ninomiya, Y., Pedchenko, V. K., Pfaff, S. L., et al. (2007) · Cell · doi:10.1016/j.cell.2007.02.035 · Cited by 241 · see citing works
The F3/11 cell adhesion molecule mediates the repulsion of neurons by the extracellular matrix glycoprotein J1-160/180
Pesheva, P., Gennarini, G., Goridis, C., & Schachner, M. (1993) · Neuron · doi:10.1016/0896-6273(93)90243-k · Cited by 241 · see citing works
Obstructed neuronal migration along radial glial fibers in the neocortex of the reeler mouse: A golgi-EM analysis
Pinto-Lord, M. C., Evrard, P., & Caviness, V. S. (1982) · Developmental Brain Research · doi:10.1016/0165-3806(82)90181-x · Cited by 240 · see citing works
A mechanism for inside-out lamination in the neocortex
Cooper, J. A. (2008) · Trends in Neurosciences · doi:10.1016/j.tins.2007.12.003 · Cited by 236 · see citing works
Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus
Bukalo, O., Schachner, M., & Dityatev, A. (2001) · Neuroscience · doi:10.1016/s0306-4522(01)00082-3 · Cited by 236 · see citing works
Acetylcholine receptor-aggregating activity of agrin isoforms and mapping of the active site.
Gesemann, M., Denzer, A. J., & Ruegg, M. A. (1995) · The Journal of cell biology · doi:10.1083/jcb.128.4.625 · Cited by 236 · see citing works
Knockout mice reveal a contribution of the extracellular matrix molecule tenascin-C to neural precursor proliferation and migration
Garcion, E., Faissner, A., & ffrench‐Constant, C. (2001) · Development · doi:10.1242/dev.128.13.2485 · Cited by 235 · see citing works
Vitronectin and thrombospondin promote retinal neurite outgrowth: Developmental regulation and role of integrins
Neugebauer, K. M., Emmett, C. J., Venstrom, K., & Reichardt, L. F. (1991) · Neuron · doi:10.1016/0896-6273(91)90244-t · Cited by 234 · see citing works
Synergistic activities of α3 and α6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse
Arcangelis, A. D., Mark, M. P., Kreidberg, J. A., Sorokin, L. M., & Georges‐Labouesse, E. (1999) · Development · doi:10.1242/dev.126.17.3957 · Cited by 231 · see citing works
Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain
Saghatelyan, A., de Chevigny, A., Schachner, M., & Lledo, P. (2004) · Nature Neuroscience · doi:10.1038/nn1211 · Cited by 229 · see citing works
Wrapping it up: the cell biology of myelination
Simons, M., & Trotter, J. (2007) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2007.08.003 · Cited by 227 · see citing works
Reelin mRNA Expression During Mouse Brain Development
Schiffmann, S. N., Bernier, B., & Goffinet, A. M. (1997) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.1997.tb01456.x · Cited by 227 · see citing works
Down-regulation of dendritic spine and glutamic acid decarboxylase 67 expressions in the reelin haploinsufficient heterozygous reeler mouse
Liu, W., Pesold, C., Rodríguez, M. Á., Carboni, G., Auta, J., Lacor, P. N., Larson, J., Condie, B. G., Guidotti, A., & Costa, E. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.051614698 · Cited by 226 · see citing works
A New Binding Motif for the Transcriptional Repressor REST Uncovers Large Gene Networks Devoted to Neuronal Functions
Otto, S. J., McCorkle, S., Hover, J., Conaco, C., Han, J., Impey, S., Yochum, G. S., Dunn, J. J., Goodman, R. H., & Mandel, G. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.0091-07.2007 · Cited by 226 · see citing works
Radial glia and neural stem cells
Malatesta, P., Appolloni, I., & Calzolari, F. (2007) · Cell and Tissue Research · doi:10.1007/s00441-007-0481-8 · Cited by 225 · see citing works
NMDA receptor surface trafficking and synaptic subunit composition are developmentally regulated by the extracellular matrix protein Reelin
Groc, L., Choquet, D., Stephenson, F. A., Verrier, D., Manzoni, O. J., & Chavis, P. (2007) · The Journal of Neuroscience · doi:10.1523/jneurosci.1772-07.2007 · Cited by 225 · see citing works
Neurons from radial glia: the consequences of asymmetric inheritance
Fishell, G., & Kriegstein, A. R. (2003) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(03)00013-8 · Cited by 224 · see citing works
Interaction of reelin signaling and Lis1 in brain development
Assadi, A. H., Zhang, G., Beffert, U., McNeil, R. S., Renfro, A., Niu, S., Quattrocchi, C. C., Antalffy, B. A., Sheldon, M., Armstrong, D. D., et al. (2003) · Nature Genetics · doi:10.1038/ng1257 · Cited by 219 · see citing works
Reelin regulates postnatal neurogenesis and enhances spine hypertrophy and long-term potentiation
Pujadas, L., Gruart, A., Bosch, C., Delgado, L., Teixeira, C. M., Rossi, D., de Lecea, L., Martínez, A., Delgado-García, J. M., & Soriano, E. (2010) · The Journal of Neuroscience · doi:10.1523/jneurosci.5284-09.2010 · Cited by 219 · see citing works
Neuron-glia communication in the control of oligodendrocyte function and myelin biogenesis
Simons, M., & Trajković, K. (2006) · Journal of Cell Science · doi:10.1242/jcs.03242 · Cited by 218 · see citing works
Interaction between Reelin and Notch Signaling Regulates Neuronal Migration in the Cerebral Cortex
Hashimoto‐Torii, K., Torii, M., Sarkisian, M. R., Bartley, C. M., Shen, J., Radtke, F., Gridley, T., Šestan, N., & RAKIC, P. T. (2008) · Neuron · doi:10.1016/j.neuron.2008.09.026 · Cited by 216 · see citing works
Phosphatidylinositol 3-kinase interacts with the adaptor protein Dab1 in response to Reelin signaling and is required for normal cortical lamination
Bock, H. H., Jossin, Y., Liu, P., Förster, E., May, P., Goffinet, A. M., & Herz, J. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m306416200 · Cited by 213 · see citing works
Local Presentation of Substrate Molecules Directs Axon Specification by Cultured Hippocampal Neurons
Esch, T., Lemmon, V., & Banker, G. A. (1999) · Journal of Neuroscience · doi:10.1523/jneurosci.19-15-06417.1999 · Cited by 212 · see citing works
The integrin family of cell adhesion molecules has multiple functions within the CNS
Milner, R., & Campbell, I. L. (2002) · Journal of Neuroscience Research · doi:10.1002/jnr.10321 · Cited by 212 · see citing works
PIP3 is involved in neuronal polarization and axon formation
Ménager, C., Arimura, N., Fukata, Y., & Kaibuchi, K. (2004) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2004.02302.x · Cited by 211 · see citing works
The Netrin family of guidance factors: emphasis on Netrin-1 signalling
Barallobre, M. J., Pascual, M., del Rı́o, J. A., & Soriano, E. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2004.11.003 · Cited by 211 · see citing works
Purification of a factor that promotes neurite outgrowth: isolation of laminin and associated molecules.
Lander, A. D., Fujii, D. K., & Reichardt, L. F. (1985) · The Journal of Cell Biology · doi:10.1083/jcb.101.3.898 · Cited by 208 · see citing works
Activation of a Dab1/CrkL/C3G/Rap1 Pathway in Reelin-Stimulated Neurons
Ballif, B. A., Arnaud, L., Arthur, W. T., Guris, D. L., Imamoto, A., & Cooper, J. A. (2004) · Current Biology · doi:10.1016/j.cub.2004.03.038 · Cited by 208 · see citing works
Contributions of astrocytes to synapse formation and maturation — Potential functions of the perisynaptic extracellular matrix
Faissner, A., Pyka, M., Geissler, M., Sobik, T., Frischknecht, R., Gundelfinger, E. D., & Seidenbecher, C. (2010) · Brain Research Reviews · doi:10.1016/j.brainresrev.2010.01.001 · Cited by 207 · see citing works
Acetylcholinesterase Clustering at the Neuromuscular Junction Involves Perlecan and Dystroglycan
Peng, H. B., Xie, H. M., Rossi, S. G., & Rotundo, R. L. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.145.4.911 · Cited by 207 · see citing works
Extracellular matrix components associated with remodeling processes in brain
Rauch, U. (2004) · Cellular and Molecular Life Sciences (CMLS) · doi:10.1007/s00018-004-4043-x · Cited by 205 · see citing works
Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin‐R in the rat spinal cord
Galtrey, C. M., Kwok, J. C. F., Carulli, D., Rhodes, K. E., & Fawcett, J. W. (2008) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2008.06108.x · Cited by 203 · see citing works
Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice
QIU, S., KORWEK, K., PRATTDAVIS, A., PETERS, M., BERGMAN, M., & WEEBER, E. (2006) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2005.11.001 · Cited by 202 · see citing works
Cell-surface heparan sulfate is involved in the repulsive guidance activities of Slit2 protein
Hu, H. (2001) · Nature Neuroscience · doi:10.1038/89482 · Cited by 201 · see citing works
Interaction of the N-Terminal Domain of the AMPA Receptor GluR4 Subunit with the Neuronal Pentraxin NP1 Mediates GluR4 Synaptic Recruitment
Sia, G.-M., Béïque, J.-C., Rumbaugh, G., Cho, R., Worley, P. F., & Huganir, R. L. (2007) · Neuron · doi:10.1016/j.neuron.2007.06.020 · Cited by 201 · see citing works
Thrombospondin 1 accelerates synaptogenesis in hippocampal neurons through neuroligin 1
Xu, J., Xiao, N., & Xia, J. (2009) · Nature Neuroscience · doi:10.1038/nn.2459 · Cited by 200 · see citing works
The Dystroglycan Complex Is Necessary for Stabilization of Acetylcholine Receptor Clusters at Neuromuscular Junctions and Formation of the Synaptic Basement Membrane
Jacobson, C., Côté, P. D., Rossi, S. G., Rotundo, R. L., & Carbonetto, S. (2001) · The Journal of Cell Biology · doi:10.1083/jcb.152.3.435 · Cited by 199 · see citing works
The Central Fragment of Reelin, Generated by Proteolytic ProcessingIn Vivo, Is Critical to Its Function during Cortical Plate Development
Jossin, Y., Ignatova, N. G., Hiesberger, T., Herz, J., de Rouvroit, C. L., & Goffinet, A. M. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.3408-03.2004 · Cited by 198 · see citing works
Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin β4 cytoplasmic domain
Murgia, C., Blaikie, P., Kim, N. V., Dans, M. J., Petrie, H. T., & Giancotti, F. G. (1998) · The EMBO Journal · doi:10.1093/emboj/17.14.3940 · Cited by 198 · see citing works
Regulation of Schwann cell function by the extracellular matrix
Chernousov, M. A., Yu, W., Chen, Z., Carey, D. J., & Strickland, S. (2008) · Glia · doi:10.1002/glia.20740 · Cited by 197 · see citing works
Chondroitinase ABCI Improves Locomotion and Bladder Function following Contusion Injury of the Rat Spinal Cord
Caggiano, A. O., Zimber, M. P., Ganguly, A., Blight, A. R., & Gruskin, E. A. (2005) · Journal of Neurotrauma · doi:10.1089/neu.2005.22.226 · Cited by 189 · see citing works
BMP and FGF regulate the development of EGF-responsive neural progenitor cells
Lillien, L. E., & Raphael, H. E. (2000) · Development · doi:10.1242/dev.127.22.4993 · Cited by 188 · see citing works
Properly formed but improperly localized synaptic specializations in the absence of laminin α4
Patton, B. L., Cunningham, J. M., Thyboll, J., Kortesmaa, J., Westerblad, H., Edström, L., Tryggvason, K., & Sanes, J. R. (2001) · Nature Neuroscience · doi:10.1038/88414 · Cited by 187 · see citing works
β1 Integrin Maintains Integrity of the Embryonic Neocortical Stem Cell Niche
Loulier, K., Lathia, J. D., Marthiens, V., Relucio, J. L. V., Mughal, M. R., Tang, S., Coksaygan, T., Hall, P. E., Chigurupati, S., Patton, B. L., et al. (2009) · PLoS Biology · doi:10.1371/journal.pbio.1000176 · Cited by 184 · see citing works
Neural differentiation of human embryonic stem cells
Dhara, S. K., & Stice, S. L. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21891 · Cited by 179 · see citing works
Neuronal Pentraxins Mediate Synaptic Refinement in the Developing Visual System
Bjartmar, L., Huberman, A. D., Ullian, E. M., Renteria, R. C., Liu, X., Xu, W., Prezioso, J., Susman, M. W., Stellwagen, D., Stokes, C. C., et al. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.4212-05.2006 · Cited by 179 · see citing works
Molecular characterization and in situ mRNA localization of the neural recognition molecule J1-160/180: a modular structure similar to tenascin.
Fuss, B., Wintergerst, E. S., Bartsch, U., & Schachner, M. (1993) · The Journal of Cell Biology · doi:10.1083/jcb.120.5.1237 · Cited by 177 · see citing works
Integrins direct Src family kinases to regulate distinct phases of oligodendrocyte development
Colognato, H., Ramachandrappa, S., Olsen, I. M. L., & ffrench‐Constant, C. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200404076 · Cited by 177 · see citing works
A neuronal cell line (PC12) expresses two β1-class integrins—α1β1, and α3β1—that recognize different neurite outgrowth-promoting domains in laminin
Tomaselli, K. J., Hall, D. E., Flier, L. A., Gehlsen, K. R., Turner, D. C., Carbonetto, S., & Reichardt, L. F. (1990) · Neuron · doi:10.1016/0896-6273(90)90219-6 · Cited by 177 · see citing works
Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system
Itoh, A., Miyabayashi, T., Ohno, M., & Sakano, S. (1998) · Molecular Brain Research · doi:10.1016/s0169-328x(98)00224-1 · Cited by 177 · see citing works
Impairment of L-type Ca2+Channel-Dependent Forms of Hippocampal Synaptic Plasticity in Mice Deficient in the Extracellular Matrix Glycoprotein Tenascin-C
Evers, M. R., Salmen, B., Bukalo, O., Rollenhagen, A., Bösl, M. R., Morellini, F., Bartsch, U., Dityatev, A., & Schachner, M. (2002) · The Journal of Neuroscience · doi:10.1523/jneurosci.22-16-07177.2002 · Cited by 172 · see citing works
Coordinate control of axon defasciculation and myelination by laminin-2 and -8
Yang, D., Bierman, J., Tarumi, Y. S., Zhong, Y.-P., Rangwala, R. A., Proctor, T. M., Miyagoe‐Suzuki, Y., Takeda, S., Miner, J. H., Sherman, L. S., et al. (2005) · The Journal of Cell Biology · doi:10.1083/jcb.200411158 · Cited by 171 · see citing works
Influence of janusin and tenascin on growth cone behavior in vitro
Taylor, J., Pesheva, P., & Schachner, M. (1993) · Journal of Neuroscience Research · doi:10.1002/jnr.490350402 · Cited by 170 · see citing works
Demyelinating Peripheral Neuropathy in Merosin-Deficient Congenital Muscular Dystrophy
Shorer, Z., Philpot, J., Francesco Muntoni, A., Sewry, C. A., & Dubowitz, V. (1995) · Journal of Child Neurology · doi:10.1177/088307389501000610 · Cited by 170 · see citing works
Integrin-linked kinase is required for laminin-2–induced oligodendrocyte cell spreading and CNS myelination
Chun, S. J., Rasband, M. N., Sidman, R. L., Habib, A. A., & Vartanian, T. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200304154 · Cited by 170 · see citing works
Identification of integrin α3β1 as a neuronal thrombospondin receptor mediating neurite outgrowth
DeFreitas, M. F., Yoshida, C. K., Frazier, W. A., Mendrick, D. L., Kypta, R. M., & Reichard, L. F. (1995) · Neuron · doi:10.1016/0896-6273(95)90038-1 · Cited by 169 · see citing works
Brevican Is Degraded by Matrix Metalloproteinases and Aggrecanase-1 (ADAMTS4) at Different Sites
Nakamura, H., Fujii, Y., Inoki, I., Sugimoto, K., Tanzawa, K., Matsuki, H., Miura, R., Yamaguchi, Y., & Okada, Y. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m003875200 · Cited by 168 · see citing works
Disabled-1-Regulated Adhesion of Migrating Neurons to Radial Glial Fiber Contributes to Neuronal Positioning during Early Corticogenesis
Sanada, K., Gupta, A., & Tsai, L. (2004) · Neuron · doi:10.1016/s0896-6273(04)00222-3 · Cited by 166 · see citing works
Susceptibility of developing cochlear nucleus neurons to deafferentation-induced death abruptly ends just before the onset of hearing
Tierney, T. S., Russell, F. A., & Moore, D. R. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970210)378:2 · Cited by 166 · see citing works
β1 Integrins Control the Formation of Cell Chains in the Adult Rostral Migratory Stream
Belvindrah, R., Hankel, S., Walker, J. R., Patton, B. L., & Müller, U. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.2991-06.2007 · Cited by 166 · see citing works
Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice
Arikawa‐Hirasawa, E., Rossi, S. G., Rotundo, R. L., & Yamada, Y. (2002) · Nature Neuroscience · doi:10.1038/nn801 · Cited by 166 · see citing works
β1-Integrins Are Required for Hippocampal AMPA Receptor-Dependent Synaptic Transmission, Synaptic Plasticity, and Working Memory
Chan, C.-S., Weeber, E. J., Zong, L., Fuchs, E., Sweatt, J. D., & Davis, R. L. (2006) · The Journal of Neuroscience · doi:10.1523/jneurosci.4110-05.2006 · Cited by 165 · see citing works
Extracellular Matrix and Visual Cortical Plasticity
Berardi, N., Pizzorusso, T., & Maffei, L. (2004) · Neuron · doi:10.1016/j.neuron.2004.12.008 · Cited by 163 · see citing works
Time of neuron origin in the hippocampus and dentate gyrus of normal and reeler mutant mice: An autoradiographic analysis
Caviness, V. S. (1973) · Journal of Comparative Neurology · doi:10.1002/cne.901510203 · Cited by 163 · see citing works
Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons
Hack, I., Hellwig, S., Junghans, D., Brunne, B., Bock, H. H., Zhao, S., & Frotscher, M. (2007) · Development · doi:10.1242/dev.005447 · Cited by 162 · see citing works
Schwann Cell-Specific Ablation of Laminin γ1 Causes Apoptosis and Prevents Proliferation
Yu, W., Feltri, M. L., Wrabetz, L. G., Strickland, S., & Chen, Z. (2005) · Journal of Neuroscience · doi:10.1523/jneurosci.5032-04.2005 · Cited by 162 · see citing works
Comm function in commissural axon guidance: cell-autonomous sorting of Robo in vivo
Keleman, K., Ribeiro, C., & Dickson, B. J. (2005) · Nature Neuroscience · doi:10.1038/nn1388 · Cited by 160 · see citing works
Distinct Roles of the β1-Class Integrins at the Developing and the Mature Hippocampal Excitatory Synapse
Huang, Z., Shimazu, K., Woo, N. H., Zang, K., Müller, U., Lu, B., & Reichardt, L. F. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3526-06.2006 · Cited by 159 · see citing works
The thrombospondin type 1 repeat superfamily
Tucker, R. P. (2004) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2003.12.011 · Cited by 159 · see citing works
Upregulation of aggrecan, link protein 1, and hyaluronan synthases during formation of perineuronal nets in the rat cerebellum
Carulli, D., Rhodes, K. E., & Fawcett, J. W. (2007) · Journal of Comparative Neurology · doi:10.1002/cne.21231 · Cited by 158 · see citing works
Induction by agrin of ectopic and functional postsynaptic-like membrane in innervated muscle
Jones, G., Meier, T., Lichtsteiner, M., Witzemann, V., Sakmann, B. J., & Brenner, H. R. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.6.2654 · Cited by 157 · see citing works
Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes
Haubst, N., Georges‐Labouesse, E., Arcangelis, A. D., Mayer, U., & Götz, M. (2006) · Development · doi:10.1242/dev.02486 · Cited by 157 · see citing works
The embryonic development of the cerebellum in normal and reeler mutant mice
Goffinet, A. M. (1983) · Anatomy and Embryology · doi:10.1007/bf00305400 · Cited by 152 · see citing works
Neuron-Astrocyte Signaling in the Development and Plasticity of Neural Circuits
Stevens, B. (2008) · Neurosignals · doi:10.1159/000123038 · Cited by 151 · see citing works
Cholinergic and noncholinergic tegmental pedunculopontine projection neurons in rats revealed by intracellular labeling
Takakusaki, K., Shiroyama, T., Yamamoto, T., & Kitai, S. T. (1996) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19960729)371:3 · Cited by 150 · see citing works
Increased axon regeneration in astrocytes grown in the presence of proteoglycan synthesis inhibitors
Smith‐Thomas, L. C., Stevens, J., Fok‐Seang, J., Faissner, A., ROGERS, J. H., & Fawcett, J. W. (1995) · Journal of Cell Science · doi:10.1242/jcs.108.3.1307 · Cited by 149 · see citing works
The Roles of the Dystrophin-Associated Glycoprotein Complex at the Synapse
Pilgram, G. S. K., Potikanond, S., Baines, R., Fradkin, L. G., & Noordermeer, J. N. (2009) · Molecular Neurobiology · doi:10.1007/s12035-009-8089-5 · Cited by 148 · see citing works
β1 Integrins in Radial Glia But Not in Migrating Neurons Are Essential for the Formation of Cell Layers in the Cerebral Cortex
Belvindrah, R., Graus-Porta, D., Goebbels, S., Nave, K., & Müller, U. (2007) · Journal of Neuroscience · doi:10.1523/jneurosci.4494-07.2007 · Cited by 147 · see citing works
Home at Last: Neural Stem Cell Niches Defined
Miller, F. D., & Gauthier-Fisher, A. (2009) · Cell stem cell · doi:10.1016/j.stem.2009.05.008 · Cited by 140 · see citing works
Laminin enhances the growth of human neural stem cells in defined culture media
Hall, P. E., Lathia, J. D., Caldwell, M. A., & ffrench‐Constant, C. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-71 · Cited by 139 · see citing works
Axon guidance at the midline: of mice and flies
Evans, T. A., & Bashaw, G. J. (2010) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2009.12.006 · Cited by 138 · see citing works
Regulation of Radial Glial Survival by Signals from the Meninges
Radakovits, R., Barros, C. S., Belvindrah, R., Patton, B., & Muller, U. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.5537-08.2009 · Cited by 135 · see citing works
Self-citation
Patterns of laminins and integrins in the embryonic ventricular zone of the CNS
Lathia, J. D., Patton, B. L., Eckley, D. M., Magnus, T., Mughal, M. R., Sasaki, T., Caldwell, M. A., Rao, M. S., Mattson, M. P., & ffrench‐Constant, C. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21520 · Cited by 135 · see citing works
Laminins promote postsynaptic maturation by an autocrine mechanism at the neuromuscular junction
Nishimune, H., Valdez, G., Jarad, G., Moulson, C. L., Müller, U., Miner, J. H., & Sanes, J. R. (2008) · The Journal of Cell Biology · doi:10.1083/jcb.200805095 · Cited by 131 · see citing works
Emerging topics in Reelin function
Förster, E., Bock, H. H., Herz, J., Chai, X., Frotscher, M., & Zhao, S. (2010) · European Journal of Neuroscience · doi:10.1111/j.1460-9568.2010.07222.x · Cited by 130 · see citing works
β1-Integrins Are Critical for Cerebellar Granule Cell Precursor Proliferation
Blaess, S., Graus-Porta, D., Belvindrah, R., Radakovits, R., Pons, S., Littlewood-Evans, A., Senften, M., Guo, H., Li, Y., Miner, J. H., et al. (2004) · Journal of Neuroscience · doi:10.1523/jneurosci.5241-03.2004 · Cited by 130 · see citing works
Proteoglycans in the nervous system — the quest for functional roles in vivo
Hartmann, U., & Maurer, P. (2001) · Matrix Biology · doi:10.1016/s0945-053x(00)00137-2 · Cited by 129 · see citing works
Quaternary Associations of Acetylcholinesterase
Bon, S., Coussen, F., & Massoulié, J. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.5.3016 · Cited by 128 · see citing works
SCO-spondin: a new member of the thrombospondin family secreted by the subcommissural organ is a candidate in the modulation of neuronal aggregation
Gobron, S., Monnerie, H., Meiniel, R., Creveaux, I., Lehmann, W., Lamalle, D., Dastugue, B., & Meiniel, A. (1996) · Journal of Cell Science · doi:10.1242/jcs.109.5.1053 · Cited by 128 · see citing works
Reelin, Very-Low-Density Lipoprotein Receptor, and Apolipoprotein E Receptor 2 Control Somatic NMDA Receptor Composition during Hippocampal MaturationIn Vitro
Sinagra, M., Verrier, D., Frankova, D., Korwek, K. M., Blahos, J., Weeber, E. J., Manzoni, O. J., & Chavis, P. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.1757-05.2005 · Cited by 128 · see citing works
The extracellular matrix and synapses
Dityatev, A., & Schachner, M. (2006) · Cell and Tissue Research · doi:10.1007/s00441-006-0217-1 · Cited by 128 · see citing works
Impaired Neuronal Positioning and Dendritogenesis in the Neocortex after Cell-Autonomous Dab1 Suppression
Olson, E. C., Kim, S., & Walsh, C. A. (2006) · Journal of Neuroscience · doi:10.1523/jneurosci.3000-05.2006 · Cited by 126 · see citing works

Flagged first, then by citations

5 of the 332 references couldn’t be matched to a known paper.

Sorted by citations

The Fibroblast Growth Factor signaling pathway
Ornitz, D. M., & Itoh, N. (2015) · WIREs Developmental Biology · doi:10.1002/wdev.176 · Cited by 2,050 · see citing works
Three-dimensional in vitro cell culture models in drug discovery and drug repositioning
Langhans, S. A. (2018) · Frontiers in Pharmacology · doi:10.3389/fphar.2018.00006 · Cited by 1,522 · see citing works
Extracellular Matrix Assembly: A Multiscale Deconstruction
Mouw, J. K., Ou, G., & Weaver, V. M. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3902 · Cited by 1,534 · see citing works
The Matrisome: In Silico Definition and In Vivo Characterization by Proteomics of Normal and Tumor Extracellular Matrices
Naba, A., Clauser, K. R., Hoersch, S., Liu, H., Carr, S. A., & Hynes, R. O. (2012) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m111.014647 · Cited by 1,354 · see citing works
Overview of the Matrisome--An Inventory of Extracellular Matrix Constituents and Functions
Hynes, R. O., & Naba, A. (2012) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a004903 · Cited by 1,349 · see citing works
Extracellular matrix: A dynamic microenvironment for stem cell niche
Gattazzo, F., Urciuolo, A., & Bonaldo, P. (2014) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2014.01.010 · Cited by 1,304 · see citing works
Proteoglycan form and function: A comprehensive nomenclature of proteoglycans
Iozzo, R. V., & Schaefer, L. (2015) · Matrix Biology · doi:10.1016/j.matbio.2015.02.003 · Cited by 1,264 · see citing works
A guide to the composition and functions of the extracellular matrix
Karamanos, N. K., Theocharis, A. D., Piperigkou, Z., Manou, D., Passi, A. G., Skandalis, S. S., Vynios, D. H., Orian‐Rousseau, V., Ricard‐Blum, S., Schmelzer, C. E. H., et al. (2021) · FEBS Journal · doi:10.1111/febs.15776 · Cited by 1,100 · see citing works
The extracellular matrix: tools and insights for the "omics" era
Naba, A., Clauser, K. R., Ding, H., Whittaker, C. A., Carr, S. A., & Hynes, R. O. (2016) · Matrix Biology · doi:10.1016/j.matbio.2015.06.003 · Cited by 1,037 · see citing works
Molecular Identity of Human Outer Radial Glia during Cortical Development
Pollen, A. A., Nowakowski, T. J., Chen, J., Retallack, H., Sandoval-Espinosa, C., Nicholas, C. R., Shuga, J., Liu, S. J., Oldham, M. C., Diaz, A., et al. (2015) · Cell · doi:10.1016/j.cell.2015.09.004 · Cited by 908 · see citing works
Materials and technologies for soft implantable neuroprostheses
Lacour, S. P., Courtine, G., & Guck, J. (2016) · Nature Reviews Materials · doi:10.1038/natrevmats.2016.63 · Cited by 738 · see citing works
The ThrombospondinsPreprint
Adams, J. C., & Lawler, J. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a009712 · Cited by 468 · see citing works
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
Cho, A.-N., Jin, Y., An, Y., Kim, J., Choi, Y. S., Lee, J. S., Kim, J., Choi, W.-Y., Koo, D.-J., Yu, W., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-24775-5 · Cited by 397 · see citing works
Transcriptomes of germinal zones of human and mouse fetal neocortex suggest a role of extracellular matrix in progenitor self-renewal
Fietz, S. A., Lachmann, R., Brandl, H., Kircher, M., Samusik, N., Schröder, R., Lakshmanaperumal, N., Henry, I., Vogt, J., Riehn, A., et al. (2012) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1209647109 · Cited by 337 · see citing works
Astrocyte-encoded positional cues maintain sensorimotor circuit integrity
Molofsky, A. V., Kelley, K. W., Tsai, H., Redmond, S., Chang, S., Madireddy, L., Chan, J. R., Baranzini, S. E., Ullian, E. M., & Rowitch, D. H. (2014) · Nature · doi:10.1038/nature13161 · Cited by 316 · see citing works
Heparan Sulfate: Biosynthesis, Structure, and Function
Li, J.-P., & Kusche‐Gullberg, M. (2016) · International review of cytology · doi:10.1016/bs.ircmb.2016.02.009 · Cited by 302 · see citing works
The evolution of metazoan extracellular matrix
Hynes, R. O. (2012) · The Journal of Cell Biology · doi:10.1083/jcb.201109041 · Cited by 274 · see citing works
3D neural tissue models: From spheroids to bioprinting
Zhuang, P., Sun, A. X., An, J., Chua, C. K., & Chew, S. Y. (2017) · Biomaterials · doi:10.1016/j.biomaterials.2017.10.002 · Cited by 269 · see citing works
How the extracellular matrix shapes neural development
Long, K. R., & Huttner, W. Β. (2019) · Open Biology · doi:10.1098/rsob.180216 · Cited by 270 · see citing works
Organic electrode coatings for next-generation neural interfaces
Robles, U. A. A., Woolley, A. J., Poole-Warren, L. A., Lovell, N. H., & Green, R. A. (2014) · Frontiers in Neuroengineering · doi:10.3389/fneng.2014.00015 · Cited by 255 · see citing works
Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing
Ishihara, J., Ishihara, A., Fukunaga, K., Sasaki, K., White, M. J. V., Briquez, P. S., & Hubbell, J. A. (2018) · Nature Communications · doi:10.1038/s41467-018-04525-w · Cited by 234 · see citing works
Astrocyte-immune cell interactions in physiology and pathology
Han, R. T., Kim, R. D., Molofsky, A. V., & Liddelow, S. A. (2021) · Immunity · doi:10.1016/j.immuni.2021.01.013 · Cited by 223 · see citing works
Cartilage oligomeric matrix protein: COMPopathies and beyond
Posey, K. L., Coustry, F., & Hecht, J. T. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.02.023 · Cited by 221 · see citing works
The brain interstitial system: Anatomy, modeling, in vivo measurement, and applications
Lei, Y., Han, H., Yuan, F., Javeed, A., & Zhao, Y. L. (2016) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2015.12.007 · Cited by 215 · see citing works
Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys
Aïd, M., Abbink, P., Larocca, R. A., Boyd, M. B., Nityanandam, R., Nanayakkara, O., Martinot, A. J., Moseley, E. T., Blass, E., Borducchi, E. N., et al. (2017) · Cell · doi:10.1016/j.cell.2017.04.008 · Cited by 201 · see citing works
Hydrogel systems and their role in neural tissue engineering
Madhusudanan, P., Raju, G., & Shankarappa, S. A. (2020) · Journal of The Royal Society Interface · doi:10.1098/rsif.2019.0505 · Cited by 201 · see citing works
Regulation of protein glycosylation and sorting by the Golgi matrix proteins GRASP55/65
Xiang, Y., Zhang, X., Nix, D. B., Katoh, T., Aoki, K., Tiemeyer, M., & Wang, Y. (2013) · Nature Communications · doi:10.1038/ncomms2669 · Cited by 189 · see citing works
Secretory phospholipase A2 enzymes as pharmacological targets for treatment of disease
Quach, N. D., Arnold, R. D., & Cummings, B. S. (2014) · Biochemical Pharmacology · doi:10.1016/j.bcp.2014.05.022 · Cited by 180 · see citing works
Wiring the Vascular Network with Neural Cues: A CNS Perspective
Wälchli, T., Wacker, A., Frei, K., Regli, L., Schwab, M. E., Hoerstrup, S. P., Gerhardt, H., & Engelhardt, B. (2015) · Neuron · doi:10.1016/j.neuron.2015.06.038 · Cited by 178 · see citing works
Astrocyte-Secreted Matricellular Proteins in CNS Remodelling during Development and Disease
Jones, E. V., & Bouvier, D. S. (2014) · Neural Plasticity · doi:10.1155/2014/321209 · Cited by 171 · see citing works
Design of Injectable Materials to Improve Stem Cell Transplantation
Marquardt, L. M., & Heilshorn, S. C. (2016) · Current Stem Cell Reports · doi:10.1007/s40778-016-0058-0 · Cited by 170 · see citing works
Role of CD47 in Hematological Malignancies
Eladl, E., Tremblay‐LeMay, R., Rastgoo, N., Musani, R., Chen, W.-M., Liu, A., & Chang, H. (2020) · Journal of Hematology & Oncology · doi:10.1186/s13045-020-00930-1 · Cited by 161 · see citing works
Extracellular Matrix Regulation in Physiology and in Brain Disease
Soles, A., Selimovic, A., Sbrocco, K., Ghannoum, F. J., Hamel, K. A., Labrada-Moncada, F. E., Gilliat, S., & Cvetanović, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24087049 · Cited by 157 · see citing works
Losing the sugar coating: Potential impact of perineuronal net abnormalities on interneurons in schizophrenia
Berretta, S., Pantazopoulos, H., Markota, M., Brown, C., & Batzianouli, E. T. (2015) · Schizophrenia Research · doi:10.1016/j.schres.2014.12.040 · Cited by 152 · see citing works
Golgi Structure and Function in Health, Stress, and Diseases
Li, J., Ahat, E., & Wang, Y. (2019) · Results and problems in cell differentiation · doi:10.1007/978-3-030-23173-6_19 · Cited by 148 · see citing works
The Interplay between Glioblastoma and Its Microenvironment
Dapash, M., Hou, D., Castro, B. A., Lee-Chang, C., & Lesniak, M. S. (2021) · Cells · doi:10.3390/cells10092257 · Cited by 148 · see citing works
3D Bioprinting of Neural Tissues
Cadena, M., Ning, L., King, A. T., Hwang, B., Jin, L., Serpooshan, V., & Sloan, S. A. (2020) · Advanced Healthcare Materials · doi:10.1002/adhm.202001600 · Cited by 147 · see citing works
Neuron-Glia Interactions in Neural Plasticity: Contributions of Neural Extracellular Matrix and Perineuronal Nets
Dzyubenko, E., Gottschling, C., & Faissner, A. (2016) · Neural Plasticity · doi:10.1155/2016/5214961 · Cited by 134 · see citing works
Extracellular Matrix in Development: Insights from Mechanisms Conserved between Invertebrates and VertebratesPreprint
Brown, N. H. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a005082 · Cited by 127 · see citing works
Microfluidic Brain-on-a-Chip: Perspectives for Mimicking Neural System Disorders
Jahromi, M. A. M., Abdoli, A., Rahmanian, M., Bardania, H., Bayandori, M., Basri, S. M. M., Kalbasi, A., Aref, A. R., Karimi, M., & Hamblin, M. R. (2019) · Molecular Neurobiology · doi:10.1007/s12035-019-01653-2 · Cited by 138 · see citing works
Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies
Dingle, Y. L., Boutin, M. E., Chirila, A. M., Livi, L. L., Labriola, N. R., Jakubek, L. M., Morgan, J. R., Darling, E. M., Kauer, J. A., & Hoffman–Kim, D. (2015) · Tissue Engineering Part C Methods · doi:10.1089/ten.tec.2015.0135 · Cited by 132 · see citing works
Astrocyte-derived small extracellular vesicles promote synapse formation via fibulin-2-mediated TGF-β signaling
Patel, M. R., & Weaver, A. M. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108829 · Cited by 120 · see citing works
Cell migration promotes dynamic cellular interactions to control cerebral cortex morphogenesis
Silva, C. G., Peyre, E., & Nguyen, L. (2019) · Nature reviews. Neuroscience · doi:10.1038/s41583-019-0148-y · Cited by 117 · see citing works
Generation of retinal ganglion cells with functional axons from human induced pluripotent stem cells
Tanaka, T., Yokoi, T., Tamalu, F., Watanabe, S., Nishina, S., & Azuma, N. (2015) · Scientific Reports · doi:10.1038/srep08344 · Cited by 121 · see citing works
A bimodular mechanism of calcium control in eukaryotes
Tidow, H., Poulsen, L. R., Andreeva, A. E., Knudsen, M., Hein, K. L., Wiuf, C., Palmgren, M. B., & Nissen, P. (2012) · Nature · doi:10.1038/nature11539 · Cited by 122 · see citing works
Advancing models of neural development with biomaterials
Roth, J. G., Huang, M. S., Li, T. L., Feig, V. R., Jiang, Y., Cui, B., Greely, H. T., Bao, Z., Pașca, S. P., & Heilshorn, S. C. (2021) · Nature reviews. Neuroscience · doi:10.1038/s41583-021-00496-y · Cited by 120 · see citing works
Conical expansion of the outer subventricular zone and the role of neocortical folding in evolution and development
Lewitus, É., Kelava, I., & Huttner, W. Β. (2013) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2013.00424 · Cited by 121 · see citing works
In Sickness and in Health: Perineuronal Nets and Synaptic Plasticity in Psychiatric Disorders
Pantazopoulos, H., & Berretta, S. (2015) · Neural Plasticity · doi:10.1155/2016/9847696 · Cited by 118 · see citing works
Roles of Heat Shock Factor 1 in Neuronal Response to Fetal Environmental Risks and Its Relevance to Brain Disorders
Hashimoto‐Torii, K., Torii, M., Fujimoto, M., Nakai, A., Fatimy, R. E., Mezger, V., Ju, M. J., Ishii, S., Chao, S.-H., Brennand, K., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.03.002 · Cited by 118 · see citing works
The extracellular matrix compartment of neural stem and glial progenitor cells
Faissner, A., & Reinhard, J. (2015) · Glia · doi:10.1002/glia.22839 · Cited by 117 · see citing works
Cell Membrane Transport Mechanisms: Ion Channels and Electrical Properties of Cell Membranes
Kulbacka, J., Choromańska, A., Rossowska, J., Weżgowiec, J., Saczko, J., & Rols, M. (2017) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-319-56895-9_3 · Cited by 113 · see citing works
Heparan Sulfate Proteoglycans as Emerging Players in Synaptic Specificity
Condomitti, G., & de Wit, J. (2018) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2018.00014 · Cited by 110 · see citing works
Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons
Álvarez, Z., Ortega, J. A., Sato, K., Sasselli, I. R., Edelbrock, A. N., Qiu, R., Marshall, K. A., Nguyen, T. P., Smith, C. S., Quinlan, K. A., et al. (2023) · Cell stem cell · doi:10.1016/j.stem.2022.12.010 · Cited by 109 · see citing works
Regional variations in stiffness in live mouse brain tissue determined by depth-controlled indentation mapping
Antonovaité, N., Beekmans, S. V., Hol, E. M., Wadman, W. J., & Iannuzzi, D. (2018) · Scientific Reports · doi:10.1038/s41598-018-31035-y · Cited by 107 · see citing works
Three dimensional in vitro models of cancer: Bioprinting multilineage glioblastoma models
Hermida, M. A., Kumar, J. D., Schwarz, D., Laverty, K. G., Bartolo, A. D., Ardron, M., Bogomolnijs, M., Clavreul, A., Brennan, P. M., Wiegand, U. K., et al. (2019) · Advances in Biological Regulation · doi:10.1016/j.jbior.2019.100658 · Cited by 105 · see citing works
Collagen in the central nervous system: contributions to neurodegeneration and promise as a therapeutic target
Wareham, L. K., Baratta, R. O., Buono, B. J. D., Schlumpf, E., & Calkins, D. J. (2024) · Molecular Neurodegeneration · doi:10.1186/s13024-024-00704-0 · Cited by 104 · see citing works
ADAMTS expression and function in central nervous system injury and disorders
Gottschall, P. E., & Howell, M. D. (2015) · Matrix Biology · doi:10.1016/j.matbio.2015.01.014 · Cited by 100 · see citing works
Extracellular matrix control of dendritic spine and synapse structure and plasticity in adulthood
Levy, A. D., Omar, M. H., & Koleske, A. J. (2014) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00116 · Cited by 96 · see citing works
Perineuronal nets and schizophrenia: The importance of neuronal coatings
Bitanihirwe, B. K. Y., & Woo, T.-U. W. (2014) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2014.03.018 · Cited by 95 · see citing works
Harnessing cerebrospinal fluid circulation for drug delivery to brain tissues
Naseri Kouzehgarani, G., Feldsien, T., Engelhard, H. H., Mirakhur, K. K., Phipps, C., Nimmrich, V., Clausznitzer, D., & Lefebvre, D. R. (2021) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2021.03.002 · Cited by 95 · see citing works
Cell adhesion promotion strategies for signal transduction enhancement in microelectrode array in vitro electrophysiology: An introductory overview and critical discussion
Blau, A. W. (2013) · Current Opinion in Colloid & Interface Science · doi:10.1016/j.cocis.2013.07.005 · Cited by 93 · see citing works
N-Glycosylation in Regulation of the Nervous System
Scott, H. A., & Panin, V. M. (2014) · Advances in neurobiology · doi:10.1007/978-1-4939-1154-7_17 · Cited by 90 · see citing works
Gastrointestinal disorders in joint hypermobility syndrome/Ehlers‐Danlos syndrome hypermobility type: A review for the gastroenterologist
Beckers, A. B., Keszthelyi, D., Fikree, A., Vork, L., Masclee, A., Farmer, A. D., & Aziz, Q. (2017) · Neurogastroenterology & Motility · doi:10.1111/nmo.13013 · Cited by 90 · see citing works
Roles of blood-brain barrier integrins and extracellular matrix in stroke
Edwards, D. N., & Bix, G. J. (2018) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00151.2018 · Cited by 90 · see citing works
Tenascin-C in the matrisome of neural stem and progenitor cells
Faissner, A., Roll, L., & Theocharidis, U. (2016) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2016.11.003 · Cited by 89 · see citing works
Matrices, scaffolds & carriers for cell delivery in nerve regeneration
Wang, Z. Z., & Sakiyama‐Elbert, S. E. (2018) · Experimental Neurology · doi:10.1016/j.expneurol.2018.09.020 · Cited by 88 · see citing works
Laminins and their receptors in the CNS
Nirwane, A. M., & Yao, Y. (2018) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12454 · Cited by 85 · see citing works
High and Low Molecular Weight Hyaluronic Acid Differentially Influences Oxylipins Synthesis in Course of Neuroinflammation
Chistyakov, D. V., Astakhova, A. A., Azbukina, N. V., Goriainov, S. V., Chistyakov, V. V., & Sergeeva, M. G. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20163894 · Cited by 87 · see citing works
The Extracellular Matrix in Glioblastomas: A Glance at Its Structural Modifications in Shaping the Tumoral Microenvironment—A Systematic Review
Marino, S., Menna, G., Bonaventura, R. D., Lisi, L., Mattogno, P. P., Figà, F., Bilgin, L., D’Alessandris, Q. G., Olivi, A., & Pepa, G. M. D. (2023) · Cancers · doi:10.3390/cancers15061879 · Cited by 86 · see citing works
Prospects of peripheral nerve tissue engineering using nerve guide conduits based on silk fibroin protein and other biopolymers
Farokhi, M., Mottaghitalab, F., Shokrgozar, M. A., Kaplan, D. L., Kim, H., & Kundu, S. C. (2016) · International Materials Reviews · doi:10.1080/09506608.2016.1252551 · Cited by 84 · see citing works
Impairments in dendrite morphogenesis as etiology for neurodevelopmental disorders and implications for therapeutic treatments
Copf, T. (2016) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2016.04.008 · Cited by 85 · see citing works
A Targeted Glycan-Related Gene Screen Reveals Heparan Sulfate Proteoglycan Sulfation Regulates WNT and BMP Trans-Synaptic Signaling
Dani, N., Nahm, M., Lee, S., & Broadie, K. S. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1003031 · Cited by 81 · see citing works
Heparanase mediates renal dysfunction during early sepsis in mice
Lygizos, M. I., Yang, Y., Altmann, C. J., Okamura, K., Andrés-Hernando, A., Perez, M. J., Smith, L. P., Koyanagi, D. E., Gandjeva, A., Bhargava, R., et al. (2013) · Physiological Reports · doi:10.1002/phy2.153 · Cited by 80 · see citing works
Subtle left-right asymmetry of gene expression profiles in embryonic and foetal human brains
de Kovel, C., Lisgo, S., Fisher, S., & Francks, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-29496-2 · Cited by 71 · see citing works
T he extracellular matrix: F ocus on oligodendrocyte biology and targeting CSPG s for remyelination therapies
Pu, A., Stephenson, E. L., & Yong, V. W. (2018) · Glia · doi:10.1002/glia.23333 · Cited by 77 · see citing works
Enhanced In Vitro Biocompatibility of Chemically Modified Poly(dimethylsiloxane) Surfaces for Stable Adhesion and Long-term Investigation of Brain Cerebral Cortex Cells
Kuddannaya, S., Bao, J., & Zhang, Y. (2015) · ACS Applied Materials & Interfaces · doi:10.1021/acsami.5b09032 · Cited by 77 · see citing works
Nerve Guidance by a Decellularized Fibroblast Extracellular Matrix
Harris, G. M., Madigan, N. N., Lancaster, K. Z., Enquist, L. W., Windebank, A. J., Schwartz, J., & Schwarzbauer, J. E. (2016) · Matrix Biology · doi:10.1016/j.matbio.2016.08.011 · Cited by 76 · see citing works
Extracellular matrix and biomimetic engineering microenvironment for neuronal differentiation
Yim, E. K. F., Jain, D., Mattiassi, S., & Goh, E. K. (2019) · Neural Regeneration Research · doi:10.4103/1673-5374.266907 · Cited by 75 · see citing works
Regulation of Oligodendrocyte Functions: Targeting Lipid Metabolism and Extracellular Matrix for Myelin Repair
Marangon, D., Boccazzi, M., Lecca, D., & Fumagalli, M. (2020) · Journal of Clinical Medicine · doi:10.3390/jcm9020470 · Cited by 77 · see citing works
Adult Neurogenesis in the Subventricular Zone and Its Regulation After Ischemic Stroke: Implications for Therapeutic Approaches
Dillen, Y., Kemps, H., Gervois, P., Wolfs, E., & Bronckaers, A. (2019) · Translational Stroke Research · doi:10.1007/s12975-019-00717-8 · Cited by 75 · see citing works
Implantation of Brain-Derived Extracellular Matrix Enhances Neurological Recovery after Traumatic Brain Injury
Wu, Y., Wang, J., Shi, Y., Pu, H., Leak, R. K., Liou, A. K. F., Badylak, S. F., Liu, Z., Zhang, J., Chen, J., et al. (2017) · Cell Transplantation · doi:10.1177/0963689717714090 · Cited by 74 · see citing works
Hematopoietic versus leukemic stem cell quiescence: Challenges and therapeutic opportunities
O’Reilly, E., Zeinabad, H. A., & Szegezdi, É. (2021) · Blood Reviews · doi:10.1016/j.blre.2021.100850 · Cited by 72 · see citing works
Functional maturation of human neural stem cells in a 3D bioengineered brain model enriched with fetal brain-derived matrix
Sood, D., Cairns, D. M., Dabbi, J. M., Ramakrishnan, C., Deisseroth, K. A., Black, L. D., Santaniello, S., & Kaplan, D. L. (2019) · Scientific Reports · doi:10.1038/s41598-019-54248-1 · Cited by 70 · see citing works
CRISPR/Cas9 Screens Reveal Requirements for Host Cell Sulfation and Fucosylation in Bacterial Type III Secretion System-Mediated Cytotoxicity
Blondel, C. J., Park, J. S., Hubbard, T. P., Pacheco, A. R., Kuehl, C. J., Walsh, M. J., Davis, B. M., Gewurz, B. E., Doench, J. G., & Waldor, M. K. (2016) · Cell Host & Microbe · doi:10.1016/j.chom.2016.06.010 · Cited by 69 · see citing works
Extracellular matrix proteins involved in Alzheimer's disease.
Ma, J., Ma, C., Li, J.-J., Sun, Y., Ye, F.-F., Liu, K., & Zhang, H.-J. (2020) · Chemistry · doi:10.1002/chem.202000782 · Cited by 64 · see citing works
Collagen XV, a multifaceted multiplexin present across tissues and species
Bretaud, S., Guillon, E., Karppinen, S., Pihlajaniemi, T. A., & Ruggiero, F. (2020) · Matrix Biology Plus · doi:10.1016/j.mbplus.2020.100023 · Cited by 67 · see citing works
Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth
Iida, J., Dorchak, J., Clancy, R., Slavik, J., Ellsworth, R. E., Katagiri, Y., Pugacheva, E. N., Kuppevelt, T. H. V., Mural, R., Cutler, M. L., et al. (2014) · Experimental Cell Research · doi:10.1016/j.yexcr.2014.11.002 · Cited by 65 · see citing works
β1 Integrin-Focal Adhesion Kinase (FAK) Signaling Modulates Retinal Ganglion Cell (RGC) Survival
Santos, A. R. C., Corredor, R. G., Obeso, B. A., Trakhtenberg, E. F., Wang, Y., Ponmattam, J., Dvoriantchikova, G., Ivanov, D., Shestopalov, V. I., Goldberg, J. L., et al. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048332 · Cited by 64 · see citing works
The role of Gpi-anchored axonal glycoproteins in neural development and neurological disorders.
Gennarini, G., Bizzoca, A., Picocci, S., Puzzo, D., Corsi, P., & Furley, A. (2017) · Molecular and cellular neurosciences · doi:10.1016/j.mcn.2016.11.006 · Cited by 59 · see citing works
The multifaceted roles of perlecan in fibrosis
Lord, M. S., Tang, F., Rnjak‐Kovacina, J., Smith, J. G. W., Melrose, J., & Whitelock, J. M. (2018) · Matrix Biology · doi:10.1016/j.matbio.2018.02.013 · Cited by 63 · see citing works
Schwann cell–derived periostin promotes autoimmune peripheral polyneuropathy via macrophage recruitment
Allard, D., Wang, Y., Li, J. J., Conley, B. E., Xu, E., Sailer, D., Kimpston, C. N., Notini, R., Smith, C.-J., Köseoğlu, E., et al. (2018) · Journal of Clinical Investigation · doi:10.1172/jci99308 · Cited by 60 · see citing works
Extracellular Matrix in the Regulation of Stem Cell Differentiation
Novoseletskaya, E. S., Grigorieva, O., Efimenko, A. Y., & Kalinina, N. (2019) · Biochemistry (Moscow) · doi:10.1134/s0006297919030052 · Cited by 60 · see citing works
Laminin-derived Ile-Lys-Val-ala-Val: a promising bioactive peptide in neural tissue engineering in traumatic brain injury
Negah, S. S., khooei, A. T., Samini, F., & Gorji, A. (2017) · Cell and Tissue Research · doi:10.1007/s00441-017-2717-6 · Cited by 59 · see citing works
Review: Synthetic scaffolds to control the biochemical, mechanical, and geometrical environment of stem cell-derived brain organoids
Oksdath, M., Perrin, S. L., Bardy, C., Hilder, E. F., DeForest, C. A., Arrua, R. D., & Gomez, G. A. (2018) · APL Bioengineering · doi:10.1063/1.5045124 · Cited by 59 · see citing works
Neuromuscular junction‐on‐a‐chip: ALS disease modeling and read‐out development in microfluidic devices
de Jongh, R., Spijkers, X. M., Pasteuning-Vuhman, S., Vulto, P., & Pasterkamp, R. J. (2020) · Journal of Neurochemistry · doi:10.1111/jnc.15289 · Cited by 58 · see citing works
Lipid monolayer spontaneous curvatures: A collection of published values
Dymond, M. K. (2021) · Chemistry and Physics of Lipids · doi:10.1016/j.chemphyslip.2021.105117 · Cited by 58 · see citing works
Age‐related impairment of endothelial progenitor cell migration correlates with structural alterations of heparan sulfate proteoglycans
Williamson, K., Hamilton, A., Reynolds, J. A., Sipos, P., Crocker, I. P., Stringer, S. E., & Alexander, M. Y. (2012) · Aging Cell · doi:10.1111/acel.12031 · Cited by 58 · see citing works
Role of Matricellular Proteins in Disorders of the Central Nervous System
Jayakumar, A. R., Apeksha, A., & Norenberg, M. D. (2016) · Neurochemical Research · doi:10.1007/s11064-016-2088-5 · Cited by 58 · see citing works
The Extracellular Matrix in the Evolution of Cortical Development and Folding
Amin, S., & Borrell, V. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.604448 · Cited by 58 · see citing works
Regulation of the neural stem cell compartment by extracellular matrix constituents
Theocharidis, U., Long, K. R., ffrench‐Constant, C., & Faissner, A. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63486-3.00001-3 · Cited by 57 · see citing works

Authors: Barros, C. S., Franco, S. J., & Muller, U.
Affiliations: Scripps Research Institute (US)
ORCID: Barros, C. S.
Franco, S. J.
Venue: Cold Spring Harbor Perspectives in Biology
Publisher: Cold Spring Harbor Laboratory
Published: 2010-12-01
Volume: 3
Issue: 1
Pages: a005108-a005108
ISSN: 1943-0264 (ISSN-L)
DOI: 10.1101/cshperspect.a005108
PMC: PMC3003458
OpenAlex: W2106176161
Cited by: 506
References: 332
Citations by year: 2026: 33 · 2025: 32 · 2024: 32 · 2023: 33 · 2022: 30 · 2021: 57 · 2020: 48 · 2019: 39 · 2018: 44 · 2017: 33 · 2016: 36 · 2015: 24 · 2014: 25 · 2013: 15 · 2012: 19
Type: posted content
Language: en
Open access: bronze
doi.org
Locations: Cold Spring Harbor Perspectives in Biology (publishedVersion)
Europe PMC (PubMed Central) (publishedVersion)
PubMed Central (publishedVersion)
PubMed (publishedVersion)
PEARL (University of Plymouth) (submittedVersion)
Funders: National Institutes of Health
National Institute of Mental Health (MH078833, U01MH078833)
National Institute of Neurological Disorders and Stroke (F32NS060355, R01NS046456, NS060355)
Topics: Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Axon Guidance and Neuronal Signaling
Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
Keywords: extracellular matrix, brain development, neural stem cells, neural stem cell differentiation, neuronal migration, synapse maturation, synaptic function, extracellular matrix receptors, glycoproteins, glia, peripheral nervous system, central nervous system
MeSH terms: Reelin Protein, Animals, Axons, Cell Differentiation, Cell Movement, Extracellular Matrix, Laminin, Nerve Tissue Proteins, Nervous System, Proteoglycans, Serine Endopeptidases, Synapses, Cell Adhesion Molecules, Neuronal, Extracellular Matrix Proteins, Tenascin, Mice, Neural Stem Cells

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Extracellular Matrix: Functions in the Nervous System

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks