Prevalence of impaired awareness of hypoglycaemia in adults with Type 1 diabetes
Abstract
Aims Impaired awareness of hypoglycaemia (IAH) is thought to affect approximately 25% of people with Type 1 diabetes. While this estimate was based on retrospective information from patients in several small studies performed several years ago, validated methods of assessment have not been used in a large hospital clinic-based population to ascertain the prevalence in the present era. Methods Five hundred and eighteen people with Type 1 diabetes were recruited by random selection over a 2-year period. Participants completed a questionnaire documenting baseline characteristics and assessment of their awareness status using the method described by Gold et al. The number of episodes of severe hypoglycaemia they had experienced in the preceding year was recorded retrospectively. Results IAH was present in 19.5% of the cohort. Compared to those with normal awareness of hypoglycaemia, those with IAH were significantly older [mean +/- standard deviation (sd); 39.3 +/- 12.9 vs. 45.9 +/- 13.5 years, P Conclusions The present survey of a large hospital-based clinic population has confirmed that a significant proportion of people with Type 1 diabetes (19.5%) continue to have IAH. Despite improvements in insulin therapies, intensification of insulin regimens and innovative patient education, the prevalence of IAH remains high in Type 1 diabetes.
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The prevalence of impaired awareness of hypoglycemia (IAH) is estimated to be close to 25% in people with type 1 diabetes but is likely to be underestimated according to CGM data.
“Its prevalence is estimated to be close to 25% in people with type 1 diabetes but is likely to be underestimated according to CGM data (113).”
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- Authors
- Geddes, J., Schopman, J. E., Zammitt, N. N., & Frier, B. M.
- Affiliations
- Edinburgh Royal Infirmary (GB)
- Corresponding author
- Frier, B. M.
- Venue
- Diabetic Medicine
- Publisher
- Wiley
- Published
- 2008-04
- Volume
- 25
- Issue
- 4
- Pages
- 501-504
- ISSN
- 0742-3071 (ISSN-L)
- 1464-5491
- OpenAlex
- W2144991899
- Cited by
- 387
- References
- 5
- Citations by year
- 2026: 11 · 2025: 13 · 2024: 23 · 2023: 27 · 2022: 26 · 2021: 30 · 2020: 31 · 2019: 32 · 2018: 40 · 2017: 15 · 2016: 25 · 2015: 26 · 2014: 14 · 2013: 23 · 2012: 10
- FWCI
- 9.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Diabetic Medicine (publishedVersion)
- PubMed (publishedVersion)
- Pure Amsterdam UMC (publishedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Diabetes and associated disorders
- Keywords
- impaired awareness of hypoglycaemia, type 1 diabetes, hypoglycemia, prevalence, severe hypoglycemia, diabetes duration, age
- MeSH terms
- Adult, Ambulatory Care, Awareness, Diabetes Mellitus, Type 1, Female, Humans, Hypoglycemia, Hypoglycemic Agents, Male, Middle Aged
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