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Review Article: A new wrinkle on old skin: the role of elastic fibres in skin ageing
Open accessAbstract
Synopsis: Cutaneous ageing is the result of two distinct, biological processes which may occur concurrently: (i) the passage of time, termed intrinsic ageing and (ii) environmental influences, termed extrinsic ageing. Intrinsic ageing of the skin is a slow process which causes changes in tissue structure and impairs function in the absence of additional biological, chemical and physical factors. The clinical features of intrinsically aged skin are not usually evident until old age when, although smooth and unblemished, the skin surface appears pale and is characterized by fine wrinkles with occasional exaggerated expression lines. Functionally, intrinsically aged skin is dry and less elastic than more youthful skin. In contrast, extrinsically aged skin is exemplified by deep, coarse wrinkles, mottled hyperpigmentation and a marked loss of elasticity and recoil. The two major environmental influences which induce extrinsic ageing are: (i) chronic exposure to solar ultraviolet (UV) irradiation (termed photoageing) and (ii) smoking. This review discusses the changes associated with the ageing process in the skin, with particular emphasis on the role played by the elastic fibre network in maintaining dermal function. The review concludes with a discussion of a short‐term assay for independent assessment of the efficacy of anti‐ageing cosmetic products using the elastic fibre component fibrillin‐1 as a biomarker of extracellular matrix repair.
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“According to Farage et al. [12], skin ageing occurs inevitably as a consequence of physiological changes over time due to genetic factors and changes in cell metabolism and the tissue structure [13 -16].”
From Elastin structure and its involvement in skin photoageing (2017) · cites this paper as [14]
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“Components such as fibrillins, fibulins, microfibril-associated glycoproteins (MAGPs) -mainly MAGP1 and MAGP2, and proteoglycans form a scaffold in which tropoelastin molecules are deposited on preformed bundles of fibrillin microfibrils in the pericellular space [14, 46, 48].”
From Elastin structure and its involvement in skin photoageing (2017) · cites this paper as [14]
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In the citing paper
“Acute exposure of skin to UV radiation can cause sunburn, resulting in a large inflammatory response causing characteristic redness, swelling and heat. In addition, altered pigmentation, immune suppression and damage to the dermal extracellular matrix can occur [24,25,56,142,143].”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“Delivery of nutrients is dependent on diffusion from the vascularized dermis [24]”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“The epidermis is a challenged environment for nutrient delivery, as it lacks the blood vessels that normally deliver nutrients to cells.”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“By comparison, chronic long-term exposure to UV radiation causes premature aging of the skin, with dramatic and significant disruption to skin structure, and leads to the development of skin cancer [6,24].”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“Elastic fibres throughout the dermis are also susceptible to UV radiation, with accumulation of disorganised elastic fibre proteins evident in severely photoaged skin. Indeed, this accumulation, termed ‘solar elastosis’, is considered to be a defining characteristic of severely photoaged skin [6,22,24,126].”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“Both the epidermal and dermal layers of skin are susceptible to chronic UV exposure; however, the most profound changes occur in the extracellular matrix of the dermis [24].”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“Acute exposure of skin to UV radiation can cause sunburn, resulting in a large inflammatory response causing characteristic redness, swelling and heat. In addition, altered pigmentation, immune suppression and damage to the dermal extracellular matrix can occur [24,25,56,142,143].”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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“Elastic fibres throughout the dermis are also susceptible to UV radiation, with accumulation of disorganised elastic fibre proteins evident in severely photoaged skin. Indeed, this accumulation, termed ‘solar elastosis’, is considered to be a defining characteristic of severely photoaged skin [6,22,24,126].”
From The Roles of Vitamin C in Skin Health. (2017) · cites this paper as [24]
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Citations
Cites
Matrix Metalloproteinases: A Review
Birkedal‐Hansen, H., Moore, W. G. I., Bodden, M., Windsor, L. J., BIRKEDAL‐HANSEN, B., DeCarlo, A. A., & Engler, J. A. (1993) · Critical Reviews in Oral Biology & Medicine · doi:10.1177/10454411930040020401 · Cited by 2,980
Pathophysiology of Premature Skin Aging Induced by Ultraviolet Light
Fisher, G. J., Wang, Z., Datta, S. C., Varani, J., Kang, S., & Voorhees, J. J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711133372003 · Cited by 1,501
Van Wart, H. E., & Birkedal-Hansen, H. (1990) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.87.14.5578 · Cited by 1,475
Molecular basis of sun-induced premature skin ageing and retinoid antagonism
Fisher, G. J., Datta, S. C., Talwar, H. S., Wang, Z.-Q., Varani, J., Kang, S., & Voorhees, J. J. (1996) · Nature · doi:10.1038/379335a0 · Cited by 1,410
Kielty, C. M., Sherratt, M. J., & Shuttleworth, C. A. (2002) · Journal of Cell Science · doi:10.1242/jcs.115.14.2817 · Cited by 870
Self-citationMatrix-Degrading Metalloproteinases in Photoaging
Quan, T., Qin, Z., Xia, W., Shao, Y., Voorhees, J. J., & Fisher, G. J. (2009) · Journal of Investigative Dermatology Symposium Proceedings · doi:10.1038/jidsymp.2009.8 · Cited by 740
Varani, J., Warner, R. L., Gharaee-Kermani, M., Phan, S. H., Kang, S., Chung, J., Wang, Z., Datta, S. C., Fisher, G. J., & Voorhees, J. J. (2000) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2000.00902.x · Cited by 643
Topical tretinoin for photoaged skin
Kligman, A. M., Grove, G. L., Hirose, R., & Leyden, J. J. (1986) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(86)70242-9 · Cited by 620
Vrhovski, B., & Weiss, A. S. (1998) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1998.2580001.x · Cited by 544
Structural and functional changes of normal aging skin
Fenske, N. A., & Lober, C. W. (1986) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(86)70208-9 · Cited by 535
Mithieux, S. M., & Weiss, A. S. (2005) · Advances in protein chemistry · doi:10.1016/s0065-3233(05)70013-9 · Cited by 511
Topical Tretinoin Improves Photoaged Skin
Weiss, J. (1988) · JAMA · doi:10.1001/jama.1988.03720040019020 · Cited by 490
Photoaging of the skin from phenotype to mechanisms
Scharffetter‐Kochanek, K., Brenneisen, P., Wenk, J., Herrmann, G., Ma, W., Kuhr, L., Meewes, C., & Wlaschek, M. (2000) · Experimental Gerontology · doi:10.1016/s0531-5565(00)00098-x · Cited by 487
Zhang, H., Apfelroth, S., Hu, W., Davis, E., Sanguineti, C., Bonadio, J. F., Mecham, R. P., & Ramirez, F. (1994) · The Journal of Cell Biology · doi:10.1083/jcb.124.5.855 · Cited by 379
Pereira, L. V., D’Alessio, M., Ramirez, F., Lynch, J. R., Sykes, B. C., Pangilinan, T., & Bonadio, J. F. (1993) · Human Molecular Genetics · doi:10.1093/hmg/2.10.1762 · Cited by 356
Tissue elasticity and the ageing elastic fibre
Sherratt, M. J. (2009) · AGE · doi:10.1007/s11357-009-9103-6 · Cited by 342
Self-citationIndik, Z., Yeh, H., Ornstein-Goldstein, N., Sheppard, P., Anderson, N., Rosenbloom, J. C., Peltonen, L., & Rosenbloom, J. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.16.5680 · Cited by 334
Effects of Aging and Chronic Sun Exposure on Melanocytes in Human Skin
Gilchrest, B. A., Blog, F. B., & Szabo, G. (1979) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12581580 · Cited by 328
Oxytalan, Elaunin, And Elastic Fibers In The Human Skin
Cotta-Pereira, G., Rodrigo, G., & Bittencourt-Sampaio, S. (1976) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12481882 · Cited by 327
Structural Changes in Aging Human Skin
Montagna, W., & Carlisle, K. S. (1979) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12532761 · Cited by 323
Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils.
Zhang, H., Hu, W., & Ramirez, F. (1995) · The Journal of Cell Biology · doi:10.1083/jcb.129.4.1165 · Cited by 317
Fibrillin degradation by matrix metalloproteinases: implications for connective tissue remodelling
Ashworth, J. L., Murphy, G., Rock, M. J., Sherratt, M. J., SHAPIRO, S. D., Shuttleworth, C. A., & Kielty, C. M. (1999) · Biochemical Journal · doi:10.1042/bj3400171 · Cited by 291
Self-citationAge, sunlight, and facial skin: A histologic and quantitative study
Warren, R., Gartstein, V., Kligman, A. M., Montagna, W., Allendorf, R. A., & Ridder, G. M. (1991) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(08)80964-4 · Cited by 271
Fibrillin-1: Organization in Microfibrils and Structural Properties
Reinhardt, D. P., Keene, D. R., Corson, G. M., Pöschl, E., Bächinger, H. P., Gambee, J. E., & Sakai, L. Y. (1996) · Journal of Molecular Biology · doi:10.1006/jmbi.1996.0237 · Cited by 253
Cigarette Smoking: Risk Factor for Premature Facial Wrinkling
Kadunce, D. P., Burr, R., Gress, R. E., Kanner, R. E., Lyon, J. L., & Zone, J. J. (1991) · Annals of Internal Medicine · doi:10.7326/0003-4819-114-10-840 · Cited by 253
Enhanced Elastin and Fibrillin Gene Expression in Chronically Photodamaged Skin
Chen, Y. Q., Bernstein, E. F., Tamai, K., Shepley, K. J., Resnik, K. S., Zhang, H., Tuan, R. S., Mauviel, A., & Uitto, J. (1994) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12392693 · Cited by 234
Biochemistry of the Elastic Fibers in Normal Connective Tissues and its Alterations in Diseases
Uitto, J. (1979) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12530093 · Cited by 220
Ultraviolet A Irradiation Stimulates Collagenase Production in Cultured Human Fibroblasts
Petersen, M. J., Hansen, C. D., & Craig, S. (1992) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12616142 · Cited by 212
Facial wrinkling in men and women, by smoking status.
Ernster, V. L., Grady, D., Miike, R., Black, D., Selby, J. V., & Kerlikowske, K. M. (1995) · American Journal of Public Health · doi:10.2105/ajph.85.1.78 · Cited by 209
Matrix metalloproteinase-1 and skin ageing in smokers
Lahmann, C., Bergemann, J., Harrison, G., & Young, A. R. (2001) · The Lancet · doi:10.1016/s0140-6736(00)04220-3 · Cited by 206
Keene, D. R., Maddox, B. K., Kuo, H., Sakai, L. Y., & Glanville, R. W. (1991) · Journal of Histochemistry & Cytochemistry · doi:10.1177/39.4.2005373 · Cited by 206
Cell Adhesion to Fibrillin-1 Molecules and Microfibrils Is Mediated by α5β1 and αvβ3 Integrins
Bax, D. V., Bernard, S. E., Lomas, A., McGovern, A., Humphries, J. D., Shuttleworth, C. A., Humphries, M. J., & Kielty, C. M. (2003) · Journal of Biological Chemistry · doi:10.1074/jbc.m303159200 · Cited by 205
Daniell, H. (1971) · Annals of Internal Medicine · doi:10.7326/0003-4819-75-6-873 · Cited by 198
Histology of sun-damaged human skin
Montagna, W., Kirchner, S. J., & Carlisle, K. S. (1989) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(89)70276-0 · Cited by 194
Cell-type Specific Recognition of RGD- and Non-RGD-containing Cell Binding Domains in Fibrillin-1
Sakamoto, H., Broekelmann, T. J., Cheresh, D. A., Ramirez, F., Rosenbloom, J., & Mecham, R. P. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.9.4916 · Cited by 191
Tassabehji, M. (1998) · Human Molecular Genetics · doi:10.1093/hmg/7.6.1021 · Cited by 186
Corson, G. M., Charbonneau, N. L., Keene, D. R., & Sakai, L. Y. (2003) · Genomics · doi:10.1016/j.ygeno.2003.08.023 · Cited by 185
Watson, R. E. B., Griffiths, C. E. M., Craven, N. M., Shuttleworth, C. A., & Kielty, C. M. (1999) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.1999.00562.x · Cited by 185
Self-citationCellular, Immunologic and Biochemical Characterization of Topical Retinoic Acid—Treated Human Skin
Fisher, G. J., Esmann, J., Grifliths, C. E. M., Talwar, H. S., Duell, E. A., Hammerberg, C., Elder, J. T., Karabin, G. D., Nickoloff, B. J., Cooper, K. D., et al. (1991) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12470632 · Cited by 182
Understanding Premature Skin Aging
Uitto, J. (1997) · New England Journal of Medicine · doi:10.1056/nejm199711133372011 · Cited by 180
Chronic Solar Dermatosis: A Light and Electron Microscopic Study of the Dermis*
Mitchell, R. E. (1967) · Journal of Investigative Dermatology · doi:10.1038/jid.1967.33 · Cited by 176
Yin, L., Morita, A., & Tsuji, T. (2001) · Photodermatology, Photoimmunology & Photomedicine · doi:10.1034/j.1600-0781.2001.170407.x · Cited by 172
Cell adhesion and integrin binding to recombinant human fibrillin‐1
Pfaff, M., Reinhardt, D. P., Sakai, L. Y., & Timpl, R. (1996) · FEBS Letters · doi:10.1016/0014-5793(96)00325-0 · Cited by 169
Lin, G., Tiedemann, K., Vollbrandt, T., Peters, H., Bätge, B., Brinckmann, J., & Reinhardt, D. P. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m210611200 · Cited by 157
Nagase, T. (2001) · DNA Research · doi:10.1093/dnares/8.2.85 · Cited by 154
Elastic Fiber Structure and Assembly
Mecham, R. P., & Davis, E. C. (1994) · Elsevier eBooks · doi:10.1016/b978-0-12-775170-2.50014-7 · Cited by 153
Griffiths, C. E. M. (1995) · Archives of Dermatology · doi:10.1001/archderm.131.9.1037 · Cited by 152
Self-citationSmoker's face: an underrated clinical sign?
Model, D. (1985) · BMJ · doi:10.1136/bmj.291.6511.1760 · Cited by 139
Fibrillin mutations in Marfan syndrome and related phenotypes
Ramirez, F. (1996) · Current Opinion in Genetics & Development · doi:10.1016/s0959-437x(96)80007-4 · Cited by 135
Lee, S. S. J., Knott, V., Jovanović, J., Harlos, K., Grimes, J. M., Choulier, L., Mardon, H. J., Stuart, D. I., & Handford, P. A. (2004) · Structure · doi:10.1016/j.str.2004.02.023 · Cited by 133
Kielty, C. M., Sherratt, M. J., Marson, A., & Baldock, C. (2005) · Advances in protein chemistry · doi:10.1016/s0065-3233(05)70012-7 · Cited by 133
Self-citationBrown‐Augsburger, P., Broekelmann, T. J., Rosenbloom, J., & Mecham, R. P. (1996) · Biochemical Journal · doi:10.1042/bj3180149 · Cited by 128
Kielty, C. M., Cummings, C., Whittaker, S. P., Shuttleworth, C. A., & Grant, M. E. (1991) · Journal of Cell Science · doi:10.1242/jcs.99.4.797 · Cited by 124
Cigarette smoking associated with premature facial wrinkling: image analysis of facial skin replicas
Koh, J. S., Kang, H., Choi, S. W., & Kim, H. O. (2002) · International Journal of Dermatology · doi:10.1046/j.1365-4362.2002.01352.x · Cited by 121
Fibrillin: from domain structure to supramolecular assembly
Handford, P. A., Downing, A. K., Reinhardt, D. P., & Sakai, L. Y. (2000) · Matrix Biology · doi:10.1016/s0945-053x(00)00100-1 · Cited by 119
The aging of skin: chronoaging versus photoaging.
Oikarinen, A. (1990) · PubMed · Cited by 114
Dahlbäck, K., Ljungquist, A., Löfberg, H., Dahlbäck, B., Engvall, E., & Sakai, L. Y. (1990) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12874430 · Cited by 104
FAZIO, M. J., Olsen, D. R., Kauh, E. A., Baldwin, C. T., Indik, Z. K., Ornstein‐Goldstein, N., Yeh, H., Rosenbloom, J., & Uitto, J. (1988) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12476591 · Cited by 101
Effect of smoking on skin elastic fibres: morphometric and immunohistochemical analysis
Just, M., Ribera, M., Monsó, E., Lorenzo, J. C., & Ferrándiz, C. (2006) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2006.07575.x · Cited by 99
Petersen, E., Wågberg, F., & Ängquist, K. A. (2002) · European Journal of Vascular and Endovascular Surgery · doi:10.1053/ejvs.2002.1750 · Cited by 97
Fibrillin-rich microfibrils of the extracellular matrix: ultrastructure and assembly
Sherratt, M. J., Wess, T. J., Baldock, C., Ashworth, J. L., Purslow, P. P., Shuttleworth, C. A., & Kielty, C. M. (2001) · Micron · doi:10.1016/s0968-4328(99)00082-7 · Cited by 97
Self-citation[35] Lysyl oxidase: Preparation and role in elastin biosynthesis
Kagan, H. M., & Sullivan, K. A. (1982) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/0076-6879(82)82092-2 · Cited by 89
Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix
Kielty, C. M., Wess, T. J., Haston, L., Ashworth, J. L., Sherratt, M. J., & Shuttleworth, C. A. (2002) · Journal of Muscle Research and Cell Motility · doi:10.1023/a:1023479010889 · Cited by 87
Self-citationRepair of photoaged dermal matrix by topical application of a cosmetic ‘antiageing’ product
Watson, R. E. B., Long, S., Bowden, J. J., Bastrilles, J., Barton, S. P., & Griffiths, C. E. M. (2007) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2007.08364.x · Cited by 84
Self-citationWatson, R. E. B., Craven, N. M., Griffiths, C. E. M., Kang, S., Jones, C. J. P., & Kielty, C. M. (2001) · Journal of Investigative Dermatology · doi:10.1046/j.1523-1747.2001.01322.x · Cited by 81
Self-citationRaghunath, M., Bächi, T., Meuli, M., Altermatt, S., Gobet, R., Bruckner-Tuderman, L., & Steinmann, B. (1996) · Journal of Investigative Dermatology · doi:10.1111/1523-1747.ep12339373 · Cited by 80
Watson, R. E. B., Ogden, S., Cotterell, L., Bowden, J. J., Bastrilles, J., Long, S., & Griffiths, C. E. M. (2009) · British Journal of Dermatology · doi:10.1111/j.1365-2133.2009.09216.x · Cited by 78
Self-citationTrask, T. M., Ritty, T. M., Broekelmann, T. J., Tisdale, C., & Mecham, R. P. (1999) · Biochemical Journal · doi:10.1042/bj3400693 · Cited by 75
Fibrillin-rich microfibrils: elastic biopolymers of the extracellular matrix.
Kielty, C. M., Wess, T. J., Haston, L., Ashworth, J. L., Sherratt, M. J., & Shuttleworth, C. A. (2002) · PubMed · Cited by 73
Self-citationAge-related changes in human dermal elastic fibres
Tsuji, T., & Hamada, T. (1981) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1981.tb00882.x · Cited by 72
Berton, A., Godeau, G., Emonard, H., Baba, K., Bellon, P., Hornebeck, W., & Bellon, G. (2000) · Matrix Biology · doi:10.1016/s0945-053x(00)00057-3 · Cited by 66
Zhang, M., Pierce, R. A., Wachi, H., Mecham, R. P., & Parks, W. C. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.11.7314 · Cited by 64
Catabolism of intact fibrillin microfibrils by neutrophil elastase, chymotrypsin and trypsin
Kielty, C. M., Woolley, D. E., Whittaker, S. P., & Shuttleworth, C. A. (1994) · FEBS Letters · doi:10.1016/0014-5793(94)00818-3 · Cited by 60
Fibrillin assembly: dimer formation mediated by amino-terminal sequences
Ashworth, J. L., Kelly, V., Wilson, R., Shuttleworth, C. A., & Kielty, C. M. (1999) · Journal of Cell Science · doi:10.1242/jcs.112.20.3549 · Cited by 56
Haynes, S. L., Shuttleworth, C. A., & Kielty, C. M. (1997) · British Journal of Dermatology · doi:10.1046/j.1365-2133.1997.1762185.x · Cited by 54
Allen, H. B. (1973) · JAMA · doi:10.1001/jama.1973.03220370019004 · Cited by 51
TOPICAL RETINOIC ACID IN ACNE VULGARIS
Pedace, F. J., & Stoughton, R. B. (1971) · British Journal of Dermatology · doi:10.1111/j.1365-2133.1971.tb02533.x · Cited by 48
Piontkivska, H., Zhang, Y., Green, E. D., Program, N. C. S., & Elnitski, L. L. (2004) · BMC Genomics · doi:10.1186/1471-2164-5-31 · Cited by 41
Sherratt, M. J., Holmes, D. F., Shuttleworth, C. A., & Kielty, C. M. (2004) · Biophysical Journal · doi:10.1016/s0006-3495(04)74369-6 · Cited by 41
Self-citationSalicyloyl‐phytosphingosine: a novel agent for the repair of photoaged skin
Farwick, M., Watson, R. E. B., Rawlings, A. V., Wollenweber, U., Lersch, P., Bowden, J. J., Bastrilles, J., & Griffiths, C. E. M. (2007) · International Journal of Cosmetic Science · doi:10.1111/j.1467-2494.2007.00394.x · Cited by 32
Self-citationRaitio, A., Kontinen, J., Rasi, M., Bloigu, R., Röning, J., & Oikarinen, A. (2004) · Acta Dermato Venereologica · doi:10.1080/00015550410014969 · Cited by 24
The area of the dermo‐epidermal junction in human skin
Katzberg, A. A. (1958) · The Anatomical Record · doi:10.1002/ar.1091310408 · Cited by 24
Soffer, A. (1986) · CHEST Journal · doi:10.1378/chest.89.5.622a · Cited by 10
Age-related deterioration in the mechanical function of human dermal fibrillin microfibrils
Sherratt, M. J., Bastrilles, J., Bowden, J., Watson, R., & Griffiths, C. E. M. (2006) · Research Explorer (The University of Manchester) · Cited by 5
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- 10.1001/archderm.1995.01690210067011 · DOI
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Metadata
- Authors
- Langton, A. K., Sherratt, M. J., Griffiths, C. E. M., & Watson, R. E. B.
- Affiliations
- Manchester Academic Health Science Centre (GB)
- Corresponding author
- Watson, R. E. B.
- Venue
- International Journal of Cosmetic Science
- Publisher
- Wiley
- Published
- 2010-06-21
- Volume
- 32
- Issue
- 5
- Pages
- 330-339
- ISSN
- 0142-5463 (ISSN-L)
- 1468-2494
- OpenAlex
- W2129424926
- Cited by
- 177
- References
- 84
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 9 · 2023: 9 · 2022: 13 · 2021: 22 · 2020: 19 · 2019: 14 · 2018: 7 · 2017: 10 · 2016: 11 · 2015: 9 · 2014: 5 · 2013: 10 · 2012: 5
- FWCI
- 1.12
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- International Journal of Cosmetic Science (publishedVersion)
- PubMed (publishedVersion)
- Research Explorer (The University of Manchester) (submittedVersion, other-oa)
- Funders
- National Institute for Health and Care Research
- Manchester Biomedical Research Centre
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Connective tissue disorders research
- Health Sciences › Medicine › Dermatology › Facial Rejuvenation and Surgery Techniques
- Keywords
- skin aging, elastic fibers, intrinsic aging, extrinsic aging, photoaging, UV irradiation, smoking, fibrillin-1, extracellular matrix, anti-aging cosmetics, biomarkers, wrinkles
- MeSH terms
- Aging, Elastin, Extracellular Matrix, Humans, Protein Conformation, Skin Aging
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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