The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies
Open accessAbstract
1. A role of the immune system in muscular adaptation to physical exercise has been suggested but data from controlled human studies are scarce. The present study investigated immunological events in human blood and skeletal muscle by immunohistochemistry and flow cytometry after eccentric cycling exercise and multiple biopsies. 2. Immunohistochemical detection of neutrophil- (CD11b, CD15), macrophage- (CD163), satellite cell- (CD56) and IL-1beta-specific antigens increased similarly in human skeletal muscle after eccentric cycling exercise together with multiple muscle biopsies, or multiple biopsies only. 3. Changes in immunological variables in blood and muscle were related, and monocytes and natural killer (NK) cells appeared to have governing functions over immunological events in human skeletal muscle. 4. Delayed onset muscle soreness, serum creatine kinase activity and C-reactive protein concentration were not related to leukocyte infiltration in human skeletal muscle. 5. Eccentric cycling and/or muscle biopsies did not result in T cell infiltration in human skeletal muscle. Modes of stress other than eccentric cycling should therefore be evaluated as a myositis model in human. 6. Based on results from the present study, and in the light of previously published data, it appears plausible that muscular adaptation to physical exercise occurs without preceding muscle inflammation. Nevertheless, leukocytes seem important for repair, regeneration and adaptation of human skeletal muscle.
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Citations
Cites
Tissue Destruction by Neutrophils
Epstein, F. H., & Weiss, S. J. (1989) · New England Journal of Medicine · doi:10.1056/nejm198902093200606 · Cited by 3,950
Myofibrillar damage following intense eccentric exercise in man
Fridén, J., Sjöström, M., & Ekblom, B. (1983) · International Journal of Sports Medicine · doi:10.1055/s-2008-1026030 · Cited by 1,005 · cited 4×
“This protocol is similar to the one used by Friden et al. (1983).”
BackgroundMethodInfluentialSelf-citationSt Pierre, B. A., & Tidball, J. G. (1994) · Journal of Applied Physiology · doi:10.1152/jappl.1994.77.1.290 · Cited by 251 · cited 2×
“The appearance of CD56+ muscle cells before macrophage infiltration in both groups (Table 5) indicates a process of regeneration rather than necrosis (St Pierre & Tidball, 1994).”
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Metadata
- Authors
- Malm, C., Nyberg, P., Engström, M., Sjödin, B., Lenkei, R., Ekblom, B., & Lundberg, I.
- Venue
- The Journal of Physiology
- Publisher
- Wiley
- Published
- 2000-11
- Volume
- 529
- Issue
- 1
- Pages
- 243-262
- ISSN
- 0022-3751 (ISSN-L)
- 1469-7793
- OpenAlex
- W1992958292
- Cited by
- 388
- References
- 3
- FWCI
- 11.06
- Type
- journal article
- Language
- en
- Open access
- green
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