The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Animal models of anxiety in mice
Abstract
Among the multiple possibilities to study human pathologies, animal models remain one of the most used pathways. They allow to access to unavailable answers in human patients and to learn about mechanisms of action of drugs. Primarily developed with rats, animal models in anxiety have been adapted with a mixed success for mice, an easy‐to‐use mammal with better genetic possibilities than rats. In this review, we have focused on the most used animal models in anxiety in mice. Both conditioned and unconditioned models are described, to represent all types of animal models of anxiety. Behavioural studies require strong care for variable parameters, linked to environment, handling or paradigm; we have discussed about this topic. Finally, we focused on the consequences of re‐exposure to the apparatus. Test–retest procedures can bring in new answers, but should be deeply studied, to revalidate the whole paradigm as an animal model of anxiety.
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Citations
Cites
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Cited by
Hsiao, E. Y., McBride, S. W., Hsien, S., Sharon, G., Hyde, E. R., McCue, T., Codelli, J. A., Chow, J., Reisman, S. E., Petrosino, J. F., et al. (2013) · Cell · doi:10.1016/j.cell.2013.11.024 · Cited by 3,283
Stress-Induced Metabolic Disorder in Peripheral CD4+ T Cells Leads to Anxiety-like Behavior
Fan, K.-Q., Li, Y.-Y., Wang, H.-L., Mao, X.-T., Guo, J.-X., Wang, F., Huang, L.-J., Li, Y.-N., Ma, X.-Y., Gao, Z.-J., et al. (2019) · Cell · doi:10.1016/j.cell.2019.10.001 · Cited by 312
Behavioral methods to study anxiety in rodents
Lezak, K. R., Missig, G., & Carlezon Jr, W. A. (2017) · Dialogues in Clinical Neuroscience · doi:10.31887/dcns.2017.19.2/wcarlezon · Cited by 290
Gouveia, K., & Hurst, J. L. (2017) · Scientific Reports · doi:10.1038/srep44999 · Cited by 193
Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities
Rueda, N., Flórez, J., & Martínez-Cué, C. (2012) · Neural Plasticity · doi:10.1155/2012/584071 · Cited by 171
Metadata
- Authors
- Bourin, M., Petit‐Demoulière, B., Nic Dhonnchadha, B., & Hascöet, M.
- Venue
- Fundamental & Clinical Pharmacology
- Publisher
- Wiley
- Published
- 2007-11-20
- Volume
- 21
- Issue
- 6
- Pages
- 567-574
- ISSN
- 0767-3981 (ISSN-L)
- 1472-8206
- OpenAlex
- W2004429380
- Cited by
- 276
- References
- 33
- FWCI
- 3.02
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
