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Modulation of NF‐κB‐dependent transcription and cell survival by the SIRT1 deacetylase

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A comprehensive definition for metabolic syndrome

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Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ

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Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

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SIRT7 Deficiency Protects against Aging-Associated Glucose Intolerance and Extends Lifespan in Male Mice

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The Peroxisome Proliferator-Activated Receptor-Gamma Coactivator-1α–Heme Oxygenase 1 Axis, a Powerful Antioxidative Pathway with Potential to Attenuate Diabetic Cardiomyopathy

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Association of SIRT6 circulating levels with urinary and glycometabolic markers in pre-diabetes and diabetes

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Intermittent Fasting: A User-Friendly Method for Type 2 Diabetes Mellitus

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Human centenarian–associated SIRT6 mutants modulate hepatocyte metabolism and collagen deposition in multilineage hepatic 3D spheroids

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Sirtuin 6 and metabolic genes interplay in Warburg effect in cancers

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The role of mammalian Sirtuin 6 in cardiovascular diseases and diabetes mellitus

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Sequence variants in the bovine silent information regulator 6, their linkage and their associations with body measurements and carcass quality traits in Qinchuan cattle

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Two tagSNPs rs352493 and rs3760908 withinSIRT6Gene Are Associated with the Severity of Coronary Artery Disease in a Chinese Han Population

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Decreased Levels of Proapoptotic Factors and Increased Key Regulators of Mitochondrial Biogenesis Constitute New Potential Beneficial Features of Long-lived Growth Hormone Receptor Gene-Disrupted Mice

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SIRT6 expression and oxidative DNA damage in individuals with prediabetes and type 2 diabetes mellitus

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Role of sirtuins in hepatocellular carcinoma progression and multidrug resistance: Mechanistical and pharmacological perspectives

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Role of the histone deacetylase family in lipid metabolism: Structural specificity and functional diversity

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Macrophages Upregulate Estrogen Receptor Expression in the Model of Obesity-Associated Breast Carcinoma

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Sirtuin 6 nuclear localization at cortical brain level of young diabetic mice: An immunohistochemical study

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Aging Epigenetics

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Will the real aging Sirtuin please stand up?

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Pachymic acid modulates sirtuin 6 activity to alleviate lipid metabolism disorders

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Overexpression of SIRT6 in Porcine Fetal Fibroblasts Attenuates Cytotoxicity and Premature Senescence Caused by D-Galactose and Tert-Butylhydroperoxide

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Sequence Variants of SIRT6 Gene Promoter in Myocardial Infarction

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High calorie diet background alters the expression of sirtuins in the testes of mice under caloric restriction

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Sirtuins as Therapeutic Targets for Treating Cancer, Metabolic Diseases, and Neurodegenerative Diseases

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Liver‐specific Sirtuin6 ablation impairs liver regeneration after 2/3 partial hepatectomy

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Multiple Roles of Sirtuin 6 in Adipose Tissue Inflammation

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Hepatocyte Sirtuin 6 Protects against Atherosclerosis and Steatohepatitis by Regulating Lipid Homeostasis

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Role of sirtuins in obesity and osteoporosis: molecular mechanisms and therapeutic targets

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SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice

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Impaired reciprocal regulation between SIRT6 and TGF‐β signaling in fatty liver

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Resveratrol suppresses hepatic fatty acid synthesis and increases fatty acid β-oxidation via the microRNA-33/SIRT6 signaling pathway

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Epigenetics and Ageing

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Sirtuins as regulators of mammalian aging

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The effect of 4-hexylresorinol administration on NAD+ level and SIRT activity in Saos-2 cells

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SIRT6 in Regulation of Mitochondrial Damage and Associated Cardiac Dysfunctions: A Possible Therapeutic Target for CVDs

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Akt2 deficiency alleviates oxidative stress in the heart and liver via up-regulating SIRT6 during high-fat diet-induced obesity

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Skeletal muscle‐specific over‐expression of the nuclear sirtuin SIRT6 blocks cancer‐associated cachexia by regulating multiple targets

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Sirtuin 6 Is a Critical Epigenetic Regulator of Cancer

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Molecular integrative study on interaction domains of nuclear factor erythroid 2-related factor 2 with sirtuin 6

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Myeloid sirtuin 6 deficiency causes obesity in mice by inducing norepinephrine degradation to limit thermogenic tissue function

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The rosetta stone of successful ageing: does oral health have a role?

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A Perspective on Sirtuins in the Metabolic Syndrome

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Sirtuins in Adipose Tissue Metabolism

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Implications of altered sirtuins in metabolic regulation and oral cancer

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Obesity Prevention Effects of Avocado (Persea americana) Seed Powder in High-Fat Diet-Induced Obesity in Rats

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Caloric Restriction and Sirtuins as New Players to Reshape Male Fertility

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SIRT6 Is a Key Regulator of Pancreatic β-Cell Survival and Function During Aging

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Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

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A Practical Approach for Restoring Homeostasis in Diseases Characterized by a Chronic Oxidative Stress

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Sirtuins – universal regulators of cell function

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DNA stimulates the deacetylase SIRT6 to mono-ADP-ribosylate proteins with histidine repeats

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DNA stimulates SIRT6 to mono-ADP-ribosylate proteins within histidine repeatsPreprint

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Modulation of SIRT6 related signaling pathways of p-AKT/mTOR and NRF2/HO-1 by memantine contributes to curbing the progression of tamoxifen/HFD-induced MASH in rats

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Stimulation of auricular vagus nerve ameliorates chronic stress induced metabolic syndrome via activation of Sirtuin-6

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Sirtuins and Their Implications in the Physiopathology of Gestational Diabetes Mellitus

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Predictive Value of Sirtuins in Acute Myocardial Infarction - Bridging the Bench to the Clinical Practice

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A unique adipocyte progenitor population promotes age-related adiposityPreprint

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Lithocholic acid targets TULP3 to activate sirtuins and AMPK to retard ageingPreprint

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SIRT Family: Biological Functions and Therapeutic Targets

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Sirtuins and metabolic regulation: food and supplementation

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Biogerontology research in Israel

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Sirtuins and Aging

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Sirtuins and next generation hallmarks of cancer: cellular energetics and tumor promoting inflammation

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Inflammaging Signaling in Health Span and Life Span Regulation

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DNA Damage Responses in Atherosclerosis

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Multitasking Roles of the Mammalian Deacetylase SIRT6

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Role of Sirtuins in Adipose Tissue Development and Metabolism

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Human genetic analyses of organelles highlight the nucleus in age-related trait heritabilityPreprint

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Sirtuins as therapeutic targets in diabetes

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Rifampicin prevents diet-induced obesity through Sirt6-dependent lipolysis, adipocyte browning and lipogenesis inhibition

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Sirt6 prevents the age-related decline of H 2 S through the control of one-carbon metabolism

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Global Sirt5 deletion reshapes gut microbiota and impairs glucose metabolism in high-fat diet-induced obese mice

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Bupleurum chinense ameliorates metabolic-associated fatty liver disease by modulating Sirtuin 6

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Diverse Roles for SIRT6 in Mammalian Healthspan and Longevity

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Silent Information Regulator 2 from Trypanosoma cruzi Is a Potential Target to Infection Control

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4-Hexylresorcinol as Histone Deacetylase Inhibitor

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Nutrition in the Elderly

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Neh1 and Neh3 domains of nuclear factor erythroid 2-related factor 2 mediate its binding to NAD-dependent protein deacetylase sirtuin-6Preprint

Fu, W., Pei, J., Xiao, Z., Sun, Y., Zhang, Z., Wu, H., Wei, S., Pei, Y., & Wang, D. (2022) · Research Square · doi:10.21203/rs.3.rs-1552407/v1 · Cited by 1

Ageing in the mammalian brain

Khojah, S. M. (2015) · Enlighten: Theses (The University of Glasgow)

The Sirtuins in Aging and Metabolic Regulation

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Analysis of High Throughput Genomic Datasets Across Species

Zinman, G. (2012)

Análise de variantes polimórficas da região promotora do gene SIRT1 em pacientes com lúpus eritematoso sistêmico

Consiglio, C. R. (2013) · Americanae (AECID Library)

THE ROLE OF DENDRITIC BDNF TRANSCRIPTS ON ALTERED INHIBITORY CIRCUITRY IN AGING AND DEPRESSION

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Pentamethylquercetin inhibited the growth of hepatic ascitic tumor cell H22 by improving metabolic environment and aerobic glycolysis in monosodium glutamate-induced obese mice

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Line-1 Retrotransposition and the Impact on Aging Rodent Skeletal Muscle Tissue

Mumford, P. W. (2019)

Sirtuins in mechanistic target of rapamycin complex 1 signaling

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Sirtuin signaling in hematologic malignancies

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Recognition of nucleosomes by protein factors that regulate chromatin structure and dynamics

Lee, P. L. (2019) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/142395

Faculty Opinions recommendation of The hallmarks of aging.

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Akt2 deficiency alleviates oxidative stress in the heart and liver during high fat diet-induced obesityPreprint

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(2023) · PeerJ · doi:10.7287/peerj.14752v0.2/reviews/3

Peer Review #3 of "Implications of altered sirtuins in metabolic regulation and oral cancer (v0.1)"

(2023) · PeerJ · doi:10.7287/peerj.14752v0.1/reviews/3

Peer Review #1 of "Implications of altered sirtuins in metabolic regulation and oral cancer (v0.1)"

(2023) · PeerJ · doi:10.7287/peerj.14752v0.1/reviews/1

Peer Review #2 of "Implications of altered sirtuins in metabolic regulation and oral cancer (v0.1)"

(2023) · PeerJ · doi:10.7287/peerj.14752v0.1/reviews/2

Peer Review #2 of "Implications of altered sirtuins in metabolic regulation and oral cancer (v0.2)"

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Additional file 5 of Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

Fröhlich, J., Liorni, N., Mangoni, M., Lochmanová, G., Pírek, P., Kaštánková, N., Pata, P., Kucera, J., Chaldakov, G. N., Tonchev, A. B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26752207

Additional file 3 of Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

Fröhlich, J., Liorni, N., Mangoni, M., Lochmanová, G., Pírek, P., Kaštánková, N., Pata, P., Kucera, J., Chaldakov, G. N., Tonchev, A. B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26752201

Additional file 1 of Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

Fröhlich, J., Liorni, N., Mangoni, M., Lochmanová, G., Pírek, P., Kaštánková, N., Pata, P., Kučera, J., Chaldakov, G. N., Tonchev, A. B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26752195

Additional file 8 of Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant

Fröhlich, J., Liorni, N., Mangoni, M., Lochmanová, G., Pírek, P., Kaštánková, N., Pata, P., Kučera, J., Chaldakov, G. N., Tonchev, A. B., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26752216

The Role of Sirt6 in Obesity and Diabetes

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Oxidative Stress Induced by Excess of Adiposity Is Related to a Downregulation of Hepatic SIRT6 Expression in Obese Individuals

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IMPROVING HEALTHSPAN BY MANIPULATING SIRT6 LEVELS: HOW DOES IT WORK?

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Sirt1 protects against high-fat diet-induced metabolic damage

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