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Cited by 438

The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.

Establishment and development of intestinal microbiota in preterm neonates

Open access
Arboleya, Silvia, Binetti, Ana, Salazar, Nuria, Fernández, Nuria, Solís, Gonzalo, Hernández-Barranco, Ana, Margolles, Abelardo, los Reyes-Gavilán, Clara G., Gueimonde, Miguel·2012·FEMS Microbiology Ecology

Abstract

Microbial colonization of the infant gut is essential for the development of the intestine and the immune system. The profile of intestinal microbiota in the full-term, vaginally delivered, breast-fed infant is considered as ideally healthy. However, in preterm infants this process is challenging, mainly because of organ immaturity, antibiotics use, and hospital stay. To assist in a proper microbiota development in these infants, a detailed knowledge of the colonization process, and the differences from that of full-term breast-fed infants, is needed. We assessed the establishment of the gut microbiota and its metabolic activity in preterm neonates (n = 21) during the first 3 months of life and compared it with that of vaginally delivered, exclusively breast-fed full-term infants (n = 20) using qualitative and quantitative culture-independent methods. Differences in the gut microbiota composition between both groups were observed. Preterm infants showed higher levels of facultative anaerobic microorganisms and reduced levels of strict anaerobes such as Bifidobacterium, Bacteroides, and Atopobium. Short-chain fatty acids concentrations were lower in preterm infants during the first days of life. Alterations occur in the process of microbiota establishment in preterm infants, indicating the need for intervention strategies to counteract them.

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Crossref · 10.1111/j.1574-6941.2011.01261.x

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Metadata

Authors
Arboleya, S., Binetti, A., Salazar, N., Fernández, N., Solís, G., Hernández-Barranco, A., Margolles, A., los Reyes-Gavilán, C. G., & Gueimonde, M.
Venue
FEMS Microbiology Ecology
Published
2011-12-15
Volume
79
Issue
3
Pages
763-772
ISSN
0168-6496 (ISSN-L)
OpenAlex
W2129532618
Cited by
438
References
41
FWCI
6.58
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Establishment and development of intestinal microbiota in preterm neonates. https://app.cochat.ai/papers/10.1111/j.1574-6941.2011.01261.x
The paper
Arboleya, S., Binetti, A., Salazar, N., Fernández, N., Solís, G., Hernández-Barranco, A., Margolles, A., los Reyes-Gavilán, C. G., & Gueimonde, M. (2012). Establishment and development of intestinal microbiota in preterm neonates. FEMS Microbiology Ecology. https://doi.org/10.1111/j.1574-6941.2011.01261.x

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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