Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii

Ramirez-Farias, Carlett; Slezak, Kathleen; Fuller, Zoë; Duncan, Alan; Holtrop, Grietje; Louis, Petra

doi:10.1017/s0007114508019880

Cited by 822Microbial Metabolites in Food BiotechnologyGut microbiota and healthProbiotics and Fermented Foods

Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii

Open access

Ramirez-Farias, Carlett, Slezak, Kathleen, Fuller, Zoë, Duncan, Alan, Holtrop, Grietje, Louis, Petra·2008·British Journal of Nutrition

DOI 10.1017/s0007114508019880

Open this paper in CoChat — free account Open PDF

Abstract

Prebiotics are food ingredients that improve health by modulating the colonic microbiota. The bifidogenic effect of the prebiotic inulin is well established; however, it remains unclear which species of Bifidobacterium are stimulated in vivo and whether bacterial groups other than lactic acid bacteria are affected by inulin consumption. Changes in the faecal microbiota composition were examined by real-time PCR in twelve human volunteers after ingestion of inulin (10 g/d) for a 16-d period in comparison with a control period without any supplement intake. The prevalence of most bacterial groups examined did not change after inulin intake, although the low G+C % Gram-positive species Faecalibacterium prausnitzii exhibited a significant increase (10.3% for control period v. 14.5% during inulin intake, P=0.019). The composition of the genus Bifidobacterium was studied in four of the volunteers by clone library analysis. Between three and five Bifidobacterium spp. were found in each volunteer. Bifidobacterium adolescentis and Bifidobacterium longum were present in all volunteers, and Bifidobacterium pseudocatenulatum, Bifidobacterium animalis, Bifidobacterium bifidum and Bifidobacterium dentium were also detected. Real-time PCR was employed to quantify the four most prevalent Bifidobacterium spp., B. adolescentis, B. longum, B. pseudocatenulatum and B. bifidum, in ten volunteers carrying detectable levels of bifidobacteria. B. adolescentis showed the strongest response to inulin consumption, increasing from 0.89 to 3.9% of the total microbiota (P=0.001). B. bifidum was increased from 0.22 to 0.63% (P<0.001) for the five volunteers for whom this species was present.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Integrity signals

Registry

Crossref · 10.1017/s0007114508019880

Cites

64 of 64 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Supplementing the diet with the plant polysaccharide inulin as a prebiotic significantly increases Faecalibacterium and Bifidobacterium species.
“Other studies have focused on supplementation of the diet with plant polysaccharide inulin prebiotics, demonstrating significant increases of both Faecalibacterium and Bifidobacterium species with this dietary intervention (Ramirez-Farias et al., 2009).”
From The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy (2018) · cites this paper as Ramirez-Farias et al., 2009

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Basic local alignment search tool
Altschul, S. F., Gish, W., Miller, W., Myers, E. W., & Lipman, D. J. (1990) · Journal of Molecular Biology · doi:10.1006/jmbi.1990.9999 · Cited by 98,669 · see citing works
MUSCLE: multiple sequence alignment with high accuracy and high throughput
Edgar, R. C. (2004) · Nucleic Acids Research · doi:10.1093/nar/gkh340 · Cited by 44,662 · see citing works
Base-Calling of Automated Sequencer Traces Using Phred. I. Accuracy AssessmentPreprint
Ewing, B., Hillier, L., Wendl, M. C., & Green, P. (1998) · Genome Research · doi:10.1101/gr.8.3.175 · Cited by 6,993 · see citing works
Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities
Ewing, B., & Green, P. (1998) · Genome Research · doi:10.1101/gr.8.3.186 · Cited by 5,439 · see citing works
Multiple sequence alignment with the Clustal series of programs
Chenna, R. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg500 · Cited by 4,865 · see citing works
Dietary modulation of the human colonic microbiota: updating the concept of prebiotics
Gibson, G. R., Probert, H. M., Loo, J. V., Rastall, R. A., & Roberfroid, M. B. (2004) · Nutrition Research Reviews · doi:10.1079/nrr200479 · Cited by 2,539 · see citing works
Introducing DOTUR, a Computer Program for Defining Operational Taxonomic Units and Estimating Species Richness
Schloss, P. D., & Handelsman, J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.3.1501-1506.2005 · Cited by 2,503 · see citing works
The Phylogeny of the Genus Clostridium: Proposal of Five New Genera and Eleven New Species Combinations
Collins, M. D., Lawson, P. A., Willems, A. L., Córdoba, J. J., Fernández‐Garayzábal, J. F., GARCIA, P., Cai, J., Hippe, H., & Farrow, J. A. E. (1994) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-44-4-812 · Cited by 1,670 · see citing works
The Jalview Java alignment editor
Clamp, M. E., Cuff, J. A., Searle, S. M. J., & Barton, G. J. (2004) · Bioinformatics · doi:10.1093/bioinformatics/btg430 · Cited by 1,581 · see citing works
Current Protocols in Molecular Biology
(2018) · Current Protocols in Molecular Biology · doi:10.1002/(issn)1934-3647 · Cited by 1,395 · see citing works
The ribosomal database project (RDP-II): introducing myRDP space and quality controlled public data
Cole, J. R., Chai, B., Farris, R. J., Wang, Q., Kulam-Syed-Mohideen, A. S., McGarrell, D. M., Bandela, A. M., Cardenas, E., Garrity, G. M., & Tiedje, J. M. (2006) · Nucleic Acids Research · doi:10.1093/nar/gkl889 · Cited by 1,171 · see citing works
Development of an extensive set of 16S rDNA-targeted primers for quantification of pathogenic and indigenous bacteria in faecal samples by real-time PCR
Rinttilä, T., Kassinen, A., Malinen, E., Krogius-Kurikka, L., & Palva, A. (2004) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2004.02409.x · Cited by 1,018 · see citing works
Phylogenetic Relationships of Butyrate-Producing Bacteria from the Human Gut
Barcenilla, A., Pryde, S. E., Martin, J. C., Duncan, S. H., Stewart, C. S., Henderson, C., & Flint, H. J. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.4.1654-1661.2000 · Cited by 996 · see citing works
Reduced dietary intake of carbohydrates by obese subjects results in decreased concentrations of butyrate and butyrate-producing bacteria in feces
Duncan, S. H., Belenguer, A., Holtrop, G., Johnstone, A. M., Flint, H. J., & Lobley, G. E. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02340-06 · Cited by 941 · see citing works
Self-citation
Two Routes of Metabolic Cross-Feeding between Bifidobacterium adolescentis and Butyrate-Producing Anaerobes from the Human Gut
Belenguer, A., Duncan, S. H., Calder, A. G., Holtrop, G., Louis, P., Lobley, G. E., & Flint, H. J. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.72.5.3593-3599.2006 · Cited by 856 · see citing works
Self-citation
pH and Peptide Supply Can Radically Alter Bacterial Populations and Short-Chain Fatty Acid Ratios within Microbial Communities from the Human Colon
Walker, A. W., Duncan, S. H., McWilliam Leitch, E. C., Child, M. W., & Flint, H. J. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.7.3692-3700.2005 · Cited by 796 · see citing works
Characterization of Bacterial Communities in Feces from Healthy Elderly Volunteers and Hospitalized Elderly Patients by Using Real-Time PCR and Effects of Antibiotic Treatment on the Fecal Microbiota
Bartosch, S., Fite, A., Macfarlane, G. T., & McMurdo, M. E. T. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.6.3575-3581.2004 · Cited by 762 · see citing works
Growth requirements and fermentation products of Fusobacterium prausnitzii, and a proposal to reclassify it as Faecalibacterium prausnitzii gen. nov., comb. nov
Duncan, S. H., Hold, G. L., Harmsen, H. J. M., Stewart, C. S., & Flint, H. J. (2002) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-52-6-2141 · Cited by 735 · see citing works
Analysis of the Fecal Microbiota of Irritable Bowel Syndrome Patients and Healthy Controls with Real-Time PCR
Malinen, E., Rinttila, T., Kajander, K., Matto, J., Kassinen, A., Krogius, L., Saarela, M., Korpela, R., & Palva, A. (2005) · The American Journal of Gastroenterology · doi:10.1111/j.1572-0241.2005.40312.x · Cited by 699 · see citing works
Development of 16S rRNA-Gene-Targeted Group-Specific Primers for the Detection and Identification of Predominant Bacteria in Human Feces
Matsuki, T., Watanabe, K., Fujimoto, J., Miyamoto, Y., Takada, T., Matsumoto, K., Oyaizu, H., & Tanaka, R. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.11.5445-5451.2002 · Cited by 656 · see citing works
Review article: prebiotics in the gastrointestinal tract
Macfarlane, S., Macfarlane, G. T., & Cummings, J. H. (2006) · Alimentary Pharmacology & Therapeutics · doi:10.1111/j.1365-2036.2006.03042.x · Cited by 624 · see citing works
Fermentation of Fructooligosaccharides and Inulin by Bifidobacteria: a Comparative Study of Pure and Fecal Cultures
Rossi, M., Corradini, C., Amaretti, A., Nicolini, M., Pompei, A., Zanoni, S., & Matteuzzi, D. (2005) · Applied and Environmental Microbiology · doi:10.1128/aem.71.10.6150-6158.2005 · Cited by 546 · see citing works
DNA sequence quality trimming and vector removal
Chou, H.-H., & Holmes, M. H. (2001) · Bioinformatics · doi:10.1093/bioinformatics/17.12.1093 · Cited by 522 · see citing works
Quantification of Bacterial Groups within Human Fecal Flora by Oligonucleotide Probe Hybridization
Sghir, A., Gramet, G., Suau, A., Rochet, V., Pochart, P., & Dore, J. M. (2000) · Applied and Environmental Microbiology · doi:10.1128/aem.66.5.2263-2266.2000 · Cited by 521 · see citing works
Restricted Distribution of the Butyrate Kinase Pathway among Butyrate-Producing Bacteria from the Human Colon
Louis, P., Duncan, S. H., McCrae, S. I., Millar, J., Jackson, M. S., & Flint, H. J. (2004) · Journal of Bacteriology · doi:10.1128/jb.186.7.2099-2106.2004 · Cited by 517 · see citing works
Self-citation
PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples
Wang, R. F., Cao, W. W., & Cerniglia, C. E. (1996) · Applied and Environmental Microbiology · doi:10.1128/aem.62.4.1242-1247.1996 · Cited by 502 · see citing works
Molecular Ecological Analysis of the Gastrointestinal Microbiota: A Review
Zoetendal, E. G., Collier, C. T., Koike, S., Mackie, R. I., & Gaskins, H. R. (2004) · Journal of Nutrition · doi:10.1093/jn/134.2.465 · Cited by 481 · see citing works
Distribution of Bifidobacterial Species in Human Intestinal Microflora Examined with 16S rRNA-Gene-Targeted Species-Specific Primers
Matsuki, T., Watanabe, K., Tanaka, R., Fukuda, M., & Oyaizu, H. (1999) · Applied and Environmental Microbiology · doi:10.1128/aem.65.10.4506-4512.1999 · Cited by 457 · see citing works
Bifidobacterial Diversity in Human Feces Detected by Genus-Specific PCR and Denaturing Gradient Gel Electrophoresis
Satokari, R. M., Vaughan, E. E., Akkermans, A. D. L., Saarela, M., & de Vos, W. M. (2001) · Applied and Environmental Microbiology · doi:10.1128/aem.67.2.504-513.2001 · Cited by 444 · see citing works
Virulence Mechanisms of Bacterial Pathogens
Kudva, I. T. (2016) · ASM Press eBooks · doi:10.1128/9781555819286 · Cited by 408 · see citing works
High‐Throughput Real‐Time Quantitative Reverse Transcription PCR
Bookout, A. L., Cummins, C. L., Mangelsdorf, D. J., Pesola, J. M., & Kramer, M. F. (2006) · Current Protocols in Molecular Biology · doi:10.1002/0471142727.mb1508s73 · Cited by 401 · see citing works
Extensive Set of 16S rRNA-Based Probes for Detection of Bacteria in Human Feces
Harmsen, H. J. M., Raangs, G. C., He, T., Degener, J. E., & Welling, G. W. (2002) · Applied and Environmental Microbiology · doi:10.1128/aem.68.6.2982-2990.2002 · Cited by 401 · see citing works
Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces.
Duncan, S. H., Hold, G. L., Barcenilla, A., Stewart, C. S., & Flint, H. J. (2002) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/00207713-52-5-1615 · Cited by 368 · see citing works
Cross-Feeding between Bifidobacterium longum BB536 and Acetate-Converting, Butyrate-Producing Colon Bacteria during Growth on Oligofructose
Falony, G., Vlachou, A., Verbrugghe, K., & Vuyst, L. D. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.01296-06 · Cited by 362 · see citing works
Oligonucleotide Probes That Detect Quantitatively Significant Groups of Butyrate-Producing Bacteria in Human Feces
Hold, G. L., Schwiertz, A., Aminov, R. I., Blaut, M., & Flint, H. J. (2003) · Applied and Environmental Microbiology · doi:10.1128/aem.69.7.4320-4324.2003 · Cited by 350 · see citing works
Lactate is mainly fermented to butyrate by human intestinal microfloras but inter-individual variation is evident
Bourriaud, C., Robins, R. J., Martin, L., Kozlowski, F., Tenailleau, E., Cherbut, C., & Michel, C. (2005) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2005.02605.x · Cited by 345 · see citing works
Distribution of Î²-glucosidase and Î²-glucuronidase activity and of Î²-glucuronidase gene gus in human colonic bacteria: Î²-Glycosidase activity in human gut bacteria
Dabek, M., McCrae, S. I., Stevens, V. J., Duncan, S. H., & Louis, P. (2008) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2008.00520.x · Cited by 332 · see citing works
Self-citation
Simultaneous determination of volatile and non-volatile acidic fermentation products of anaerobes by capillary gas chromatography
Richardson, A. J., Calder, A. G., Stewart, C. S., & Smith, A. C. (1989) · Letters in Applied Microbiology · doi:10.1111/j.1472-765x.1989.tb00278.x · Cited by 326 · see citing works
Culture-dependent and culture-independent qualitative analysis of probiotic products claimed to contain bifidobacteria
Masco, L., Huys, G., De Brandt, E., Temmerman, R., & Swings, J. (2005) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2004.11.018 · Cited by 247 · see citing works
Impact of pH on Lactate Formation and Utilization by Human Fecal Microbial Communities
Belenguer, Á., Duncan, S. H., Holtrop, G., Anderson, S. E., Lobley, G. E., & Flint, H. J. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.00508-07 · Cited by 240 · see citing works
Self-citation
Proposal of Roseburia faecis sp. nov., Roseburia hominis sp. nov. and Roseburia inulinivorans sp. nov., based on isolates from human faeces
Duncan, S. H., Aminov, R. I., Scott, K. P., Louis, P., Stanton, T. B., & Flint, H. J. (2006) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.64098-0 · Cited by 197 · see citing works
Self-citation
Fusobacterium prausnitzii and Related Species Represent a Dominant Group Within the Human Fecal Flora
Suau, A., Rochet, V., Sghir, A., Gramet, G., Brewaeys, S., Sutren, M., Rigottier‐Gois, L., & Dore, J. M. (2001) · Systematic and Applied Microbiology · doi:10.1078/0723-2020-00015 · Cited by 195 · see citing works
Development of a Semiquantitative Degenerate Real-Time PCR-Based Assay for Estimation of Numbers of Butyryl-Coenzyme A (CoA) CoA Transferase Genes in Complex Bacterial Samples
Louis, P., & Flint, H. J. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.02561-06 · Cited by 192 · see citing works
Self-citation
Jerusalem artichoke and chicory inulin in bakery products affect faecal microbiota of healthy volunteers
Kleessen, B., Schwarz, S., Boehm, A., Fuhrmann, H., Richter, A., Henle, T., & Krueger, M. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507730751 · Cited by 177 · see citing works
New Real-Time Quantitative PCR Procedure for Quantification of Bifidobacteria in Human Fecal Samples
Gueimonde, M., Tölkkö, S., Korpimäki, T., & Salminen, S. (2004) · Applied and Environmental Microbiology · doi:10.1128/aem.70.7.4165-4169.2004 · Cited by 177 · see citing works
Design and validation of 16S rRNA probes to enumerate members of the Clostridium leptum subgroup in human faecal microbiota
Lay, C., Sutren, M., Rochet, V., Saunier, K., Dore, J. M., & Rigottier‐Gois, L. (2005) · Environmental Microbiology · doi:10.1111/j.1462-2920.2005.00763.x · Cited by 166 · see citing works
Fermentation and bulking capacity of indigestible carbohydrates: the case of inulin and oligofructose
NYMAN, M. E. (2002) · British Journal Of Nutrition · doi:10.1079/bjn/2002533 · Cited by 158 · see citing works
Roseburia intestinalis sp. nov., a novel saccharolytic, butyrate-producing bacterium from human faeces
Duncan, S. H. (2002) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.02143-0 · Cited by 151 · see citing works
Bifidobacteriummicrobiota and parameters of immune function in elderly subjects
Ouwehand, A. C., Bergsma, N., Parhiala, R., Lahtinen, S., Gueimonde, M., Finne-Soveri, H., Strandberg, T., PitkÃ¤lÃ¤, K., & Salminen, S. (2008) · FEMS Immunology & Medical Microbiology · doi:10.1111/j.1574-695x.2008.00392.x · Cited by 148 · see citing works
Molecular Diversity, Cultivation, and Improved Detection by Fluorescent In Situ Hybridization of a Dominant Group of Human Gut Bacteria Related toRoseburiaspp. orEubacterium rectale
Aminov, R. I., Walker, A. W., Duncan, S. H., Harmsen, H. J. M., Welling, G. W., & Flint, H. J. (2006) · Applied and Environmental Microbiology · doi:10.1128/aem.00701-06 · Cited by 129 · see citing works
Reinstatement of Species Rank for Bacteroides fragilis, B. ovatus, B. distasonis, B. thetaiotaomicron, and B. vulgatus: Designation of Neotype Strains for Bacteroides fragilis (Veillon and Zuber) Castellani and Chalmers and Bacteroides thetaiotaomicron (Distaso) Castellani and Chalmers
Cato, E. P., & JOHNSON, J. L. (1976) · International Journal of Systematic Bacteriology · doi:10.1099/00207713-26-2-230 · Cited by 123 · see citing works
Rapid identification of the species of theBacteroides fragilisgroup by multiplex PCR assays using group- and species-specific primers
Liu, C., Song, Y., McTeague, M., Vu, A., Wexler, H. M., & Finegold, S. M. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(03)00296-9 · Cited by 111 · see citing works
Inulin and oligofructose: impact on intestinal diseases and disorders
Guarner, F. (2005) · British Journal Of Nutrition · doi:10.1079/bjn20041345 · Cited by 100 · see citing works
Molecular cloning of genes from Ruminococcus flavefaciens encoding xylanase and beta(1-3,1-4)glucanase activities
Flint, H. J., McPherson, C. A., & Bisset, J. (1989) · Applied and Environmental Microbiology · doi:10.1128/aem.55.5.1230-1233.1989 · Cited by 82 · see citing works
Influence of cabbage processing methods and prebiotic manipulationof colonic microflora on glucosinolate breakdown in man
Fuller, Z., Louis, P., Mihajlovski, A., Rungapamestry, V., Ratcliffe, B., & Duncan, A. J. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507709091 · Cited by 70 · see citing works
Self-citation
Ruminal cellulolytic bacteria and protozoa from bison, cattle-bison hybrids, and cattle fed three alfalfa-corn diets
Varel, V. H., & Dehority, B. A. (1989) · Applied and Environmental Microbiology · doi:10.1128/aem.55.1.148-153.1989 · Cited by 68 · see citing works
Multiplex PCR using 16S rRNA gene-targeted primers for the identification of bifidobacteria from human origin
MulliÃ©, C., Odou, M., Singer, E., et al. (2003) · FEMS Microbiology Letters · doi:10.1016/s0378-1097(03)00245-3 · Cited by 61 · see citing works
The Effect of the Prebiotic Inulin and the Probiotic Bifidobacterium longum on the Fecal Microflora of Healthy Volunteers Measured by FISH and DGGE
Harmsen, H. J. M., Raangs, G. C., Franks, A. H., Wildeboer-Veloo, A. C. M., & Welling, G. W. (2002) · Microbial Ecology in Health and Disease · doi:10.1080/08910600310002091 · Cited by 56 · see citing works
The genes for three xylan-degrading activities from Bacteroides ovatus are clustered in a 3.8-kilobase region
Whitehead, T. R., & Hespell, R. B. (1990) · Journal of Bacteriology · doi:10.1128/jb.172.5.2408-2412.1990 · Cited by 54 · see citing works
The Effect of the Prebiotic Inulin and the ProbioticBifidobacterium longumon the Fecal Microflora of Healthy Volunteers Measured by FISH and DGGE
Harmsen, H. J. M., Raangs, G. C., Franks, A. H., Wildeboer-Veloo, A. C. M., & Welling, G. W. (2002) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v14i4.8246 · Cited by 52 · see citing works
Characterization of human intestinal bifidobacteria using competitive PCR and PCR-TTGE
Mangin, I., Suau, A., Magne, F., Garrido, D. A., Gotteland, M., Neut, C., & Pochart, P. (2005) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2005.00005.x · Cited by 44 · see citing works
Virulence Mechanisms of Bacterial Pathogens
(2007) · Wiley eBooks · doi:10.1128/9781555815851 · Cited by 44 · see citing works
Commensal Bacteria in Health and Disease
Kolenbrander, P. E., Flint, H. J., Louis, P., Scott, K. P., & Duncan, S. H. (2007) · Wiley eBooks · doi:10.1128/9781555815851.ch8 · Cited by 10 · see citing works
Self-citation
Diversity of the butyrate-producing microflora of the human gut
Barcenilla, A. (2025) · OpenGrey (Institut de l'Information Scientifique et Technique) · doi:10.48526/rgu-wt-2807291 · Cited by 5 · see citing works

Flagged first, then by citations

Sorted by citations

The Microbiota-Gut-Brain Axis
Cryan, J. F., O'Riordan, K. J., Cowan, C. S. M., Sandhu, K. V., Bastiaanssen, T. F. S., Boehme, M., Codagnone, M. G., Cussotto, S., Fulling, C., Golubeva, A. V., et al. (2019) · Physiological Reviews · doi:10.1152/physrev.00018.2018 · Cited by 5,286 · see citing works
Functional interactions between the gut microbiota and host metabolism
Tremaroli, V., & Bäckhed, F. (2012) · Nature · doi:10.1038/nature11552 · Cited by 4,387 · see citing works
Microbial degradation of complex carbohydrates in the gut
Flint, H. J., Scott, K. P., Duncan, S. H., Louis, P., & Forano, E. (2012) · Gut Microbes · doi:10.4161/gmic.19897 · Cited by 2,331 · see citing works
Self-citation
Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine
Louis, P., & Flint, H. J. (2009) · FEMS Microbiology Letters · doi:10.1111/j.1574-6968.2009.01514.x · Cited by 2,179 · see citing works
Self-citation
Dietary fiber and prebiotics and the gastrointestinal microbiota
Holscher, H. D. (2017) · Gut Microbes · doi:10.1080/19490976.2017.1290756 · Cited by 1,808 · see citing works
Dominant and diet-responsive groups of bacteria within the human colonic microbiota
Walker, A. W., Ince, J., Duncan, S. H., Webster, L. M., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., et al. (2011) · The ISME Journal · doi:10.1038/ismej.2010.118 · Cited by 1,632 · see citing works
Self-citation
How glycan metabolism shapes the human gut microbiota
Koropatkin, N. M., Cameron, E. A., & Martens, E. C. (2012) · Nature Reviews Microbiology · doi:10.1038/nrmicro2746 · Cited by 1,419 · see citing works
The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy
Gopalakrishnan, V., Helmink, B. A., Spencer, C. N., Reuben, A., & Wargo, J. A. (2018) · Cancer Cell · doi:10.1016/j.ccell.2018.03.015 · Cited by 1,392 · see citing works
Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers
Wang, T., Cai, G., Qiu, Y., Fei, N., Zhang, M., Pang, X., Jia, W., Cai, S., & Zhao, L. (2012) · The ISME Journal · doi:10.1038/ismej.2011.109 · Cited by 1,287 · see citing works
Short chain fatty acids in human gut and metabolic health
Blaak, E. E., Canfora, E. E., Theis, S., Frost, G., Groen, A. K., Mithieux, G., Nauta, A., Scott, K., Stahl, B., van Harsselaar, J., et al. (2020) · Beneficial Microbes · doi:10.3920/bm2020.0057 · Cited by 1,103 · see citing works
The influence of diet on the gut microbiota
Scott, K. P., Gratz, S. W., Sheridan, P. O., Flint, H. J., & Duncan, S. H. (2013) · Pharmacological Research · doi:10.1016/j.phrs.2012.10.020 · Cited by 1,052 · see citing works
Dietary fibre in gastrointestinal health and disease
Gill, S. K., Rossi, M., Bajka, B., & Whelan, K. (2021) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-020-00375-4 · Cited by 979 · see citing works
Effects of gut microbes on nutrient absorption and energy regulation
Krajmalnik‐Brown, R., Ilhan, Z., Kang, D., & DiBaise, J. K. (2012) · Nutrition in Clinical Practice · doi:10.1177/0884533611436116 · Cited by 852 · see citing works
Dietary fiber intervention on gut microbiota composition in healthy adults: a systematic review and meta-analysis
So, D., Whelan, K., Rossi, M., Morrison, M., Holtmann, G., Kelly, J. T., Shanahan, E. R., Staudacher, H. M., & Campbell, K. L. (2018) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqy041 · Cited by 683 · see citing works
Dietary fibre modulates the gut microbiota
Cronin, P., Joyce, S. A., O’Toole, P. W., & O’Connor, E. M. (2021) · Nutrients · doi:10.3390/nu13051655 · Cited by 658 · see citing works
Impact of diet and individual variation on intestinal microbiota composition and fermentation products in obese men
Salonen, A., Lahti, L., Salojärvi, J., Holtrop, G., Korpela, K., Duncan, S. H., Date, P., Farquharson, F., Johnstone, A. M., Lobley, G. E., et al. (2014) · The ISME Journal · doi:10.1038/ismej.2014.63 · Cited by 626 · see citing works
Self-citation
Review article: dietary fibre-microbiota interactions
Simpson, H. L., & Campbell, B. J. (2015) · Alimentary Pharmacology & Therapeutics · doi:10.1111/apt.13248 · Cited by 602 · see citing works
Fermentable carbohydrate restriction reduces luminal bifidobacteria and gastrointestinal symptoms in patients with irritable bowel syndrome
Staudacher, H. M., Lomer, M. C. E., Anderson, J. L., Barrett, J. S., Muir, J. G., Irving, P. M., & Whelan, K. (2012) · The Journal of Nutrition · doi:10.3945/jn.112.159285 · Cited by 590 · see citing works
The health benefits of dietary fiber: beyond the usual suspects of type 2 diabetes mellitus, cardiovascular disease and colon cancer
Kaczmarczyk, M. M., Miller, M. J., & Freund, G. G. (2012) · Metabolism · doi:10.1016/j.metabol.2012.01.017 · Cited by 554 · see citing works
Prebiotic inulin-type fructans induce specific changes in the human gut microbiota
Vandeputte, D., Falony, G., Vieira-Silva, S., Wang, J., Sailer, M., Theis, S., Verbeke, K., & Raes, J. (2017) · Gut · doi:10.1136/gutjnl-2016-313271 · Cited by 554 · see citing works
The Effects of Iron Fortification on the Gut Microbiota in African Children: A Randomized Controlled Trial in Cote d’Ivoire
Zimmermann, M. B., Chassard, C., Rohner, F., N'Goran, E. K., Nindjin, C., Dostal, A., Utzinger, J., Ghattas, H., Lacroix, C., & Hurrell, R. F. (2010) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.110.004564 · Cited by 520 · see citing works
Nondigestible carbohydrates, butyrate, and butyrate-producing bacteria
Fu, X., Liu, Z., Zhu, C., Mou, H., & Kong, Q. (2019) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2018.1542587 · Cited by 497 · see citing works
Increased Proportions of Bifidobacterium and the Lactobacillus Group and Loss of Butyrate-Producing Bacteria in Inflammatory Bowel Disease
Wang, W., Chen, L., Zhou, R., Wang, X., Song, L., Huang, S., Wang, G., & Xia, B. (2014) · Journal of Clinical Microbiology · doi:10.1128/jcm.01500-13 · Cited by 509 · see citing works
Feeding the microbiota–gut–brain axis: Diet, microbiome, and neuropsychiatry
Sandhu, K. V., Sherwin, E., Schellekens, H., Stanton, C., Dinan, T. G., & Cryan, J. F. (2017) · Translational Research · doi:10.1016/j.trsl.2016.10.002 · Cited by 491 · see citing works
Prebiotic Effects of Wheat Arabinoxylan Related to the Increase in Bifidobacteria, Roseburia and Bacteroides/Prevotella in Diet-Induced Obese Mice
Neyrinck, A. M., Possemiers, S., Druart, C., Van de Wiele, T., De Backer, F., Cani, P. D., Larondelle, Y., & Delzenne, N. M. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020944 · Cited by 465 · see citing works
The role of the microbiome for human health: From basic science to clinical applications
Mohajeri, M. H., Brummer, R. J. M., Rastall, R. A., Weersma, R. K., Harmsen, H. J. M., Faas, M., & Eggersdorfer, M. (2018) · European Journal of Nutrition · doi:10.1007/s00394-018-1703-4 · Cited by 440 · see citing works
Cultured Representatives of Two Major Phylogroups of Human Colonic Faecalibacterium prausnitzii Can Utilize Pectin, Uronic Acids, and Host-Derived Substrates for Growth
Lopez-Siles, M., Khan, T. M., Duncan, S. H., Harmsen, H. J. M., Garcia-Gil, L. J., & Flint, H. J. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.06858-11 · Cited by 433 · see citing works
The rumen microbial metagenome associated with high methane production in cattle
Wallace, R. J., Rooke, J. A., McKain, N., Duthie, C.-A., Hyslop, J. J., Ross, D. W., Waterhouse, A., Watson, M., & Roehe, R. (2015) · BMC Genomics · doi:10.1186/s12864-015-2032-0 · Cited by 416 · see citing works
Modulation of the human gut microbiota by dietary fibres occurs at the species level
Chung, W. S. F., Walker, A. W., Louis, P., Parkhill, J., Vermeiren, J., Bosscher, D., Duncan, S. H., & Flint, H. J. (2016) · BMC Biology · doi:10.1186/s12915-015-0224-3 · Cited by 409 · see citing works
Self-citation
A heritable subset of the core rumen microbiome dictates dairy cow productivity and emissions
Wallace, R. J., Sasson, G., Garnsworthy, P. C., Tapio, I., Gregson, E., Bani, P., Huhtanen, P., Bayat, A. R., Strozzi, F., Biscarini, F., et al. (2019) · Science Advances · doi:10.1126/sciadv.aav8391 · Cited by 410 · see citing works
The gut microbiome and its role in obesity
Davis, C. D. (2016) · Nutrition Today · doi:10.1097/nt.0000000000000167 · Cited by 407 · see citing works
Enhanced butyrate formation by cross-feeding between Faecalibacterium prausnitzii and Bifidobacterium adolescentis
Rios-Covian, D., Gueimonde, M., Duncan, S. H., Flint, H. J., & de los Reyes-Gavilan, C. G. (2015) · FEMS Microbiology Letters · doi:10.1093/femsle/fnv176 · Cited by 371 · see citing works
Randomised, double-blind, placebo-controlled trial of fructo-oligosaccharides in active Crohn's disease
Benjamin, J. L., Hedin, C. R. H., Koutsoumpas, A., Ng, S. C., McCarthy, N. E., Hart, A. L., Kamm, M. A., Sanderson, J. D., Knight, S. C., Forbes, A., et al. (2011) · Gut · doi:10.1136/gut.2010.232025 · Cited by 361 · see citing works
Probiotic Bifidobacterium strains and galactooligosaccharides improve intestinal barrier function in obese adults but show no synergism when used together as synbiotics
Krumbeck, J. A., Rasmussen, H. E., Hutkins, R. W., Clarke, J., Shawron, K., Keshavarzian, A., & Walter, J. (2018) · Microbiome · doi:10.1186/s40168-018-0494-4 · Cited by 342 · see citing works
Gastrointestinal Transit Time, Glucose Homeostasis and Metabolic Health: Modulation by Dietary Fibers
Müller, M., Canfora, E., & Blaak, E. (2018) · Nutrients · doi:10.3390/nu10030275 · Cited by 329 · see citing works
Decreased dietary fiber intake and structural alteration of gut microbiota in patients with advanced colorectal adenoma
Chen, H.-M., Yu, Y.-N., Wang, J.-L., Lin, Y.-W., Kong, X., Yang, C.-Q., Yang, L., Liu, Z.-J., Yuan, Y.-Z., Liu, F., et al. (2013) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.112.046607 · Cited by 321 · see citing works
Decreased abundance of <scp>F</scp> aecalibacterium prausnitzii in the gut microbiota of <scp>C</scp> rohn's disease
Fujimoto, T., Imaeda, H., Takahashi, K., Kasumi, E., Bamba, S., Fujiyama, Y., & Andoh, A. (2013) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.12073 · Cited by 304 · see citing works
Potential for enriching next-generation health-promoting gut bacteria through prebiotics and other dietary components
Lordan, C., Thapa, D., Ross, R. P., & Cotter, P. D. (2020) · Gut Microbes · doi:10.1080/19490976.2019.1613124 · Cited by 289 · see citing works
16S rRNA gene-based profiling of the human infant gut microbiota is strongly influenced by sample processing and PCR primer choice
Walker, A. W., Martin, J. C., Scott, P., Parkhill, J., Flint, H. J., & Scott, K. P. (2015) · Microbiome · doi:10.1186/s40168-015-0087-4 · Cited by 273 · see citing works
The hypersensitivity to colonic distension of <scp>IBS</scp> patients can be transferred to rats through their fecal microbiota
Crouzet, L., Gaultier, E., Del'Homme, C., Cartier, C., Delmas, E., Dapoigny, M., Fioramonti, J., & Bernalier‐Donadille, A. (2013) · Neurogastroenterology & Motility · doi:10.1111/nmo.12103 · Cited by 280 · see citing works
Characterization of the gut microbial community of obese patients following a weight-loss intervention using whole metagenome shotgun sequencing
Louis, S., Tappu, R.-M., Damms-Machado, A., Huson, D. H., & Bischoff, S. C. (2016) · PLoS ONE · doi:10.1371/journal.pone.0149564 · Cited by 269 · see citing works
Habitual dietary fibre intake influences gut microbiota response to an inulin-type fructan prebiotic: a randomised, double-blind, placebo-controlled, cross-over, human intervention study
Healey, G., Murphy, R., Butts, C., Brough, L., Whelan, K., & Coad, J. (2018) · British Journal Of Nutrition · doi:10.1017/s0007114517003440 · Cited by 267 · see citing works
Is butyrate the link between diet, intestinal microbiota and obesity-related metabolic diseases?
Brahe, L. K., Astrup, A., & Larsen, L. H. (2013) · Obesity Reviews · doi:10.1111/obr.12068 · Cited by 264 · see citing works
Specific substrate-driven changes in human faecal microbiota composition contrast with functional redundancy in short-chain fatty acid production
Reichardt, N., Vollmer, M., Holtrop, G., Farquharson, F. M., Wefers, D., Bunzel, M., Duncan, S. H., Drew, J. E., Williams, L. M., Milligan, G., et al. (2018) · The ISME Journal · doi:10.1038/ismej.2017.196 · Cited by 249 · see citing works
Self-citation
Dietary fiber type reflects physiological functionality: comparison of grain fiber, inulin, and polydextrose: Nutrition Reviews® Vol. 69(1): ••-••
Raninen, K., Lappi, J., Mykkänen, H., & Poutanen, K. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2010.00358.x · Cited by 254 · see citing works
Gut microbiota dysbiosis and bacterial community assembly associated with cholesterol gallstones in large-scale study
Wu, T., Zhang, Z., Liu, B., Hou, D., Liang, Y., Zhang, J., & Shi, P. (2013) · BMC Genomics · doi:10.1186/1471-2164-14-669 · Cited by 234 · see citing works
Synbiotics Alter Fecal Microbiomes, But Not Liver Fat or Fibrosis, in a Randomized Trial of Patients With Nonalcoholic Fatty Liver Disease
Scorletti, E., Afolabi, P. R., Miles, E. A., Smith, D. E., Almehmadi, A., Alshathry, A., Childs, C. E., Del Fabbro, S., Bilson, J., Moyses, H. E., et al. (2020) · Gastroenterology · doi:10.1053/j.gastro.2020.01.031 · Cited by 237 · see citing works
Causal relationship between diet-induced gut microbiota changes and diabetes: a novel strategy to transplant Faecalibacterium prausnitzii in preventing diabetes
Ganesan, K., Chung, S. K., Vanamala, J., & Xu, B. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123720 · Cited by 221 · see citing works
Association betweenFaecalibacterium prausnitziiand dietary fibre in colonic fermentation in healthy human subjects
Benus, R. F. J., van der Werf, T. S., Welling, G. W., Judd, P. A., Taylor, M. A., Harmsen, H. J. M., & Whelan, K. (2010) · British Journal Of Nutrition · doi:10.1017/s0007114510001030 · Cited by 210 · see citing works
Gut microbiota, diet, and obesity-related disorders: the good, the bad, and the future challenges
Portune, K. J., Benítez‐Páez, A., Del Pulgar, E. M. G., Cerrudo, V., & Sanz, Y. (2017) · Molecular Nutrition & Food Research · doi:10.1002/mnfr.201600252 · Cited by 201 · see citing works
Alcohol or gut microbiota: who is the guilty?
Meroni, M., Longo, M., & Dongiovanni, P. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20184568 · Cited by 183 · see citing works
Human gut microbiota: Does diet matter?
Maukonen, J., & Saarela, M. (2015) · Proceedings of The Nutrition Society · doi:10.1017/s0029665114000688 · Cited by 177 · see citing works
Understanding the prebiotic potential of different dietary fibers using an in vitro continuous adult fermentation model (PolyFermS)
Poeker, S. A., Geirnaert, A., Berchtold, L., Greppi, A., Krych, L., Steinert, R. E., de Wouters, T., & Lacroix, C. (2018) · Scientific Reports · doi:10.1038/s41598-018-22438-y · Cited by 176 · see citing works
High-Fiber, Whole-Food Dietary Intervention Alters the Human Gut Microbiome but Not Fecal Short-Chain Fatty Acids
Oliver, A., Chase, A. B., Weihe, C., Orchanian, S. B., Riedel, S. F., Hendrickson, C. L., Lay, M., Sewall, J. M., Martiny, J. B. H., & Whiteson, K. (2021) · mSystems · doi:10.1128/msystems.00115-21 · Cited by 171 · see citing works
Microbiome and Breast Cancer: New Role for an Ancient Population
Eslami-S, Z., Majidzadeh-A, K., Halvaei, S., Babapirali, F., & Esmaeili, R. (2020) · Frontiers in Oncology · doi:10.3389/fonc.2020.00120 · Cited by 153 · see citing works
Emerging prospects of macro- and microalgae as prebiotic
Patel, A. K., Singhania, R. R., Awasthi, M. K., Varjani, S., Bhatia, S. K., Tsai, M.-L., Hsieh, S.-L., Chen, C.-W., & Dong, C.-D. (2021) · Microbial Cell Factories · doi:10.1186/s12934-021-01601-7 · Cited by 156 · see citing works
The impact of nutrition on intestinal bacterial communities
Flint, H. J., Duncan, S. H., & Louis, P. (2017) · Current Opinion in Microbiology · doi:10.1016/j.mib.2017.04.005 · Cited by 149 · see citing works
Self-citation
Insights into Roseburia intestinalis which alleviates experimental colitis pathology by inducing anti‐inflammatory responses
Shen, Z., Zhu, C., Quan, Y., Yang, J., Yuan, W., Yang, Z., Wu, S., Luo, W., Tan, B., & Wang, X. (2018) · Journal of Gastroenterology and Hepatology · doi:10.1111/jgh.14144 · Cited by 133 · see citing works
Low iron availability in continuousin vitrocolonic fermentations induces strong dysbiosis of the child gut microbial consortium and a decrease in main metabolites
Dostal, A., Fehlbaum, S., Chassard, C., Zimmermann, M. B., & Lacroix, C. (2013) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2012.01461.x · Cited by 129 · see citing works
Oral Samples as non-invasive proxies for assessing the composition of the rumen microbial community
Tapio, I., Shingfield, K. J., McKain, N., Bonin, A., Fischer, D., Bayat, A. R., Vilkki, J., Taberlet, P., Snelling, T. J., & Wallace, R. J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0151220 · Cited by 125 · see citing works
Shift of hindgut microbiota and microbial short chain fatty acids profiles in dairy calves from birth to pre-weaning
Song, Y., Malmuthuge, N., Steele, M. A., & Guan, L. L. (2017) · FEMS Microbiology Ecology · doi:10.1093/femsec/fix179 · Cited by 115 · see citing works
Archaeal abundance in post-mortem ruminal digesta may help predict methane emissions from beef cattle
Wallace, R. J., Rooke, J. A., Duthie, C.-A., Hyslop, J. J., Ross, D. W., McKain, N., de Souza, S. M., Snelling, T. J., Waterhouse, A., & Roehe, R. (2014) · Scientific Reports · doi:10.1038/srep05892 · Cited by 100 · see citing works
Detrimental effect of broad-spectrum antibiotics on intestinal microbiome diversity in patients after allogeneic stem cell transplantation: lack of commensal sparing antibiotics.
Weber, D., Hiergeist, A., Weber, M., Dettmer, K., Wolff, D., Hahn, J., Herr, W., Gessner, A., & Holler, E. (2019) · Clinical Infectious Diseases · doi:10.1093/cid/ciy711 · Cited by 92 · see citing works
Molecular Nutrition Research—The Modern Way Of Performing Nutritional Science
Norheim, F., Gjelstad, I., Hjorth, M., Vinknes, K., Langleite, T., Holen, T., Jensen, J., Dalen, K., Karlsen, A., Kielland, A., et al. (2012) · Nutrients · doi:10.3390/nu4121898 · Cited by 83 · see citing works
A Novel Non-Digestible, Carrot-Derived Polysaccharide (cRG-I) Selectively Modulates the Human Gut Microbiota while Promoting Gut Barrier Integrity: An Integrated In Vitro Approach
Van den Abbeele, P., Verstrepen, L., Ghyselinck, J., Albers, R., Marzorati, M., & Mercenier, A. (2020) · Nutrients · doi:10.3390/nu12071917 · Cited by 73 · see citing works
Between Dysbiosis, Maternal Immune Activation and Autism: Is There a Common Pathway?
Suprunowicz, M., Tomaszek, N., Urbaniak, A., Zackiewicz, K., Modzelewski, S., & Waszkiewicz, N. (2024) · Nutrients · doi:10.3390/nu16040549 · Cited by 44 · see citing works
Short-term feeding of fermentable dietary fibres influences the gut microbiota composition and metabolic activity in rats
Paturi, G., Butts, C. A., Stoklosinski, H., Herath, T. D., & Monro, J. A. (2017) · International Journal of Food Science & Technology · doi:10.1111/ijfs.13543 · Cited by 35 · see citing works

Cross-feeding among bifidobacteria on glycomacropeptide
Morozumi, M., Wada, Y., Tsuda, M., Tabata, F., Ehara, T., Nakamura, H., & Miyaji, K. (2023) · Journal of Functional Foods · doi:10.1016/j.jff.2023.105463 · Cited by 13 · see citing works
Bifidobacterium-bifidum/bifidobacterium-breve/bifidobacterium-infantis/bifidobacterium-longum/lactobacillus-rhamnosus
(2021) · Reactions Weekly · doi:10.1007/s40278-021-96461-6
Characterization of Bifidobacterium Strains Using Box Primers
Gómez‐Zavaglia, A., de Urraza, P. J., & Antoni, G. D. (2000) · Anaerobe · doi:10.1006/anae.1999.0316 · Cited by 19 · see citing works
Comparative Genomics Revealed Genetic Diversity and Species/Strain-Level Differences in Carbohydrate Metabolism of Three Probiotic Bifidobacterial Species
Odamaki, T., Horigome, A., Sugahara, H., Hashikura, N., Minami, J., Xiao, J.-Z., & Abe, F. (2015) · International Journal of Genomics · doi:10.1155/2015/567809 · Cited by 50 · see citing works
Short communication: Genotype-phenotype association analysis revealed different utilization ability of 2'-fucosyllactose in Bifidobacterium genus
He, Z., Yang, B. K., Liu, X., Ross, R. P., Stanton, C., Zhao, J., Zhang, H., & Chen, W. (2020) · Journal of Dairy Science · doi:10.3168/jds.2020-19013 · Cited by 15 · see citing works

Authors: Ramirez-Farias, C., Slezak, K., Fuller, Z., Duncan, A., Holtrop, G., & Louis, P.
Affiliations: Biomathematics and Statistics Scotland (GB)
Corresponding author: Louis, Petra
ORCID: Duncan, Alan
Holtrop, Grietje
Louis, Petra
Venue: British Journal of Nutrition
Publisher: Cambridge University Press (CUP)
Published: 2008-07-01
Volume: 101
Issue: 4
Pages: 541-550
ISSN: 0007-1145 (ISSN-L)
1475-2662
DOI: 10.1017/s0007114508019880
OpenAlex: W2036057672
Cited by: 822
References: 64
Citations by year: 2026: 21 · 2025: 37 · 2024: 40 · 2023: 57 · 2022: 55 · 2021: 75 · 2020: 60 · 2019: 59 · 2018: 60 · 2017: 65 · 2016: 43 · 2015: 36 · 2014: 51 · 2013: 59 · 2012: 28
FWCI: 24.02
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.cambridge.org/core/terms (unspecified)
Locations: British Journal Of Nutrition (publishedVersion)
PubMed (publishedVersion)
Funders: Scottish Government
Topics: Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
Keywords: inulin, prebiotics, gut microbiota, Bifidobacterium adolescentis, Faecalibacterium prausnitzii, Bifidobacterium longum, Bifidobacterium bifidum, Bifidobacterium pseudocatenulatum, Bifidobacterium animalis, Bifidobacterium dentium, bifidogenic effect, fecal microbiota composition, dietary supplementation
MeSH terms: Adult, Analysis of Variance, Base Sequence, Bifidobacterium, DNA, Bacterial, Fatty Acids, Volatile, Feces, Food Microbiology, Humans, Hydrogen-Ion Concentration, Intestinal Mucosa, Inulin, Molecular Sequence Data, Species Specificity, Stimulation, Chemical, Colony Count, Microbial, Gene Library, Linear Models, DNA Fingerprinting, DNA Primers, Probiotics, Reverse Transcriptase Polymerase Chain Reaction

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Effect of inulin on the human gut microbiota: stimulation of Bifidobacterium adolescentis and Faecalibacterium prausnitzii

Abstract

Integrity signals

Claims the paper makes

Claims other papers make about this one

Self-check

Cites

Cited by

Related

Record

About these checks